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OncoArendi Therapeutics

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uuid0006xnl

Namestring
OncoArendi Therapeutics
Legal namestring
Molecure S.A.
Websiteurl
oncoarendi.com
Company typeenum
Private
Founded yearint
2012
Descriptiontext

Molecure S.A. (formerly OncoArendi Therapeutics until a March 2022 rebrand) is a publicly listed Polish biotechnology company focused on discovering, developing, and commercialising first-in-class small molecule therapeutics for neoplastic, inflammatory, and fibrotic diseases with significant unmet medical need. Founded in 2012 and headquartered in Wysokie Mazowieckie, Poland, the company trades on the Warsaw Stock Exchange under ticker OAT and operates with a clinical-stage workforce of 51-100 employees. Its lead programmes, OATD-01 and OATD-02, target inflammatory and fibrotic diseases, supported by an in-house discovery pipeline of unique and unexplored protein targets that was rationalised from five to three discovery-stage programs in October 2024.

The company's technological base combines in-house medicinal chemistry, biology, and discovery capabilities with novel target biology sourced from partnerships with leading universities worldwide, plus a cutting-edge small molecule mRNA targeting discovery platform. The approach is to identify and validate protein and mRNA targets that drive disease progression and modulate them with first-in-class small molecules, aiming to stop or reverse disease where existing therapies are inadequate. In January 2026 the company closed its RNA program and concentrated resources on its most commercially promising clinical assets, signalling a portfolio-focus pivot.

Molecure is pre-revenue with both lead candidates still in clinical development; pricing details are not publicly disclosed and there is no commercial product on market. The business model relies on equity capital via the public market, supplemented historically by non-dilutive grant funding from Poland's National Center for Research and Development (NCBiR), the Medical University of Warsaw, and EU structural funds, alongside a Seed/Series 1-2 financing history (aggregate disclosed funding roughly $16.5 million through 2017). Future monetisation is expected to follow standard pharmaceutical channels upon regulatory approval, with management including co-founder and Director of Chemistry Jacek Olczak, Chief Medical Officer Samson Fung, and President & CEO Marcin Szumowski.

Short descriptiontext

Molecure S.A. (formerly OncoArendi Therapeutics) is a publicly listed Polish biotechnology company developing first-in-class small molecule therapeutics for inflammatory, fibrotic, and neoplastic diseases, with clinical-stage assets OATD-01 and OATD-02 serving patients with high unmet medical need.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
51–100
akta.pro rankint
HeadquartersWysokie Mazowieckie, Poland
HQ citystring
Wysokie Mazowieckie
HQ countrystring
Poland
HQ regionstring
Europe
Markets served

Serves global market

Keyword5 values
small molecule drugs, inflammatory disease therapeutics, drug discovery platform, neoplastic disease treatment, protein target modulation
Industry3 codes
1Drug Discovery (Target ID/Validation & Hit Discovery)
CodeHLAIALAAPrimaryYes
2Target Identification & Validation Platforms (omics-driven, chemoproteomics, genetic validation)
CodeHLAAAIAIPrimaryNo
3Cheminformatics & Molecular Modeling / CADD
CodeHLAGAJAEPrimaryNo
NAICS code1 code
  • Pharmaceutical Preparation Manufacturing325412
SIC code1 code
  • Pharmaceutical Preparations2834
Product category
Clinical-stage Drug Discovery
Marketing channels4 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels1 record

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components5 values
Personnel, Technology or R&D, Operations, Marketing or Sales, Others
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Core offering1 text field

Molecure (formerly OncoArendi Therapeutics) discovers and develops first-in-class small molecule drugs for the treatment of neoplastic, inflammatory, and fibrotic diseases with unmet medical need. Its core pipeline comprises clinical-stage drug candidates OATD-01 and OATD-02, supported by an in-house medicinal chemistry and biology discovery capability and a small molecule mRNA targeting discovery platform that identifies and validates novel protein and mRNA targets.

Differentiator
Functional benefit
Problem solved
Product overview1 text field

Molecure (formerly OncoArendi Therapeutics) is an innovative biotechnology company discovering, developing, and commercializing novel therapeutics for neoplastic and inflammatory diseases. The company operates a diversified pipeline consisting of clinical-stage programs OATD-01 and OATD-02 for inflammatory and fibrotic diseases, alongside a cutting-edge small molecule mRNA targeting discovery platform. The company utilizes its in-house medicinal chemistry and biology capabilities to identify and validate unexplored protein and mRNA targets, modulating their activity with first-in-class small molecule drugs. The pipeline also includes discovery-stage protein target programs. In 2026, the company announced closure of its RNA program to focus on the most commercially promising projects.

Product and service2 records
1OATD-01
CategoryClinical Program
Description

A clinical-stage drug candidate targeting inflammatory and fibrotic diseases, forming part of Molecure's focused therapeutic strategy for diseases with significant unmet medical need.

2OATD-02
CategoryClinical Program
Description

A clinical-stage drug candidate for inflammatory and fibrotic diseases, part of Molecure's core clinical portfolio alongside OATD-01.

Scale indicator2 records

Each record includes

Type, Value, Description, Source

Recent move7 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight4 records

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

German drug discovery and development company with a similar model of medicinal chemistry-driven small molecule discovery partnerships; comparable in scale and pre-clinical/early-clinical focus.

TypeDirect peer
Description

Danish clinical-stage biotech developing innovative therapeutics including small molecules and peptides; comparable European biotech with similar pipeline-stage profile.

TypeBroad incumbent
Description

Finnish pharmaceutical company active in small molecule drug development, including specialty and inflammatory disease areas; broader portfolio but overlapping therapeutic focus.

TypeEmerging player
Description

UK biotech developing RNA-targeting therapeutics (siRNA); directly relevant as a peer in the small-molecule-RNA targeting space Molecure exited in 2026.

TypeDirect peer
Description

Belgian clinical-stage biotech focused on small molecule drug discovery in inflammatory and fibrotic diseases, with comparable pipeline depth and European listing (Nasdaq/AMS).

TypeEmerging player
Description

Public clinical-stage biotech developing therapeutic antibodies; different modality but comparable mid-stage clinical pipeline and discovery platform orientation.

TypeDirect peer
Description

UK-listed biotech developing first-in-class therapeutics, often in inflammatory and fibrotic disease, with a similar model of platform-driven drug discovery.

TypeEmerging player
Description

US computational chemistry/molecular modeling platform for small molecule drug discovery; comparable computational-discovery angle and peer for Molecure's cheminformatics approach.

TypeRegional player
Description

Polish clinical-stage biotech listed on the WSE developing small molecule drugs; comparable Central European peer in size, listing venue, and clinical-stage focus.

TypeBroad incumbent
Description

Italian specialty pharma with established inflammatory and rare disease franchises; comparable EU pharma peer with small molecule capabilities.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat3 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights6 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment1 record

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile1 record

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Feature3 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles3 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds5 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors3 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

OncoArendi Therapeutics

Clinical-stage Drug Discoveryoncoarendi.com

Molecure S.A. (formerly OncoArendi Therapeutics) is a publicly listed Polish biotechnology company developing first-in-class small molecule therapeutics for inflammatory, fibrotic, and neoplastic diseases, with clinical-stage assets OATD-01 and OATD-02 serving patients with high unmet medical need.

What OncoArendi Therapeutics does

Molecure S.A. (formerly OncoArendi Therapeutics until a March 2022 rebrand) is a publicly listed Polish biotechnology company focused on discovering, developing, and commercialising first-in-class small molecule therapeutics for neoplastic, inflammatory, and fibrotic diseases with significant unmet medical need. Founded in 2012 and headquartered in Wysokie Mazowieckie, Poland, the company trades on the Warsaw Stock Exchange under ticker OAT and operates with a clinical-stage workforce of 51-100 employees. Its lead programmes, OATD-01 and OATD-02, target inflammatory and fibrotic diseases, supported by an in-house discovery pipeline of unique and unexplored protein targets that was rationalised from five to three discovery-stage programs in October 2024.

The company's technological base combines in-house medicinal chemistry, biology, and discovery capabilities with novel target biology sourced from partnerships with leading universities worldwide, plus a cutting-edge small molecule mRNA targeting discovery platform. The approach is to identify and validate protein and mRNA targets that drive disease progression and modulate them with first-in-class small molecules, aiming to stop or reverse disease where existing therapies are inadequate. In January 2026 the company closed its RNA program and concentrated resources on its most commercially promising clinical assets, signalling a portfolio-focus pivot.

Molecure is pre-revenue with both lead candidates still in clinical development; pricing details are not publicly disclosed and there is no commercial product on market. The business model relies on equity capital via the public market, supplemented historically by non-dilutive grant funding from Poland's National Center for Research and Development (NCBiR), the Medical University of Warsaw, and EU structural funds, alongside a Seed/Series 1-2 financing history (aggregate disclosed funding roughly $16.5 million through 2017). Future monetisation is expected to follow standard pharmaceutical channels upon regulatory approval, with management including co-founder and Director of Chemistry Jacek Olczak, Chief Medical Officer Samson Fung, and President & CEO Marcin Szumowski.

OncoArendi Therapeutics firmographics

Firmographics
Name
OncoArendi Therapeutics
Legal name
Molecure S.A.
Website
https://oncoarendi.com
Company type
Private
Founded year
2012
Operating status
Operating
Headcount range
51–100 employees
Short description
Molecure S.A. (formerly OncoArendi Therapeutics) is a publicly listed Polish biotechnology company developing first-in-class small molecule therapeutics for inflammatory, fibrotic, and neoplastic diseases, with clinical-stage assets OATD-01 and OATD-02 serving patients with high unmet medical need.
Ownership category
akta.pro rank

OncoArendi Therapeutics industry classification

Industry
Product category
Clinical-stage Drug Discovery
NAICS
Pharmaceutical Preparation Manufacturing (325412)
SIC
Pharmaceutical Preparations (2834)
akta.pro primary industry
Drug Discovery (Target ID/Validation & Hit Discovery) (HLAIALAA)
akta.pro secondary industries
Target Identification & Validation Platforms (omics-driven, chemoproteomics, genetic validation) (HLAAAIAI), Cheminformatics & Molecular Modeling / CADD (HLAGAJAE)

Keywords

  • Small molecule drugs
  • Inflammatory disease therapeutics
  • Drug discovery platform
  • Neoplastic disease treatment
  • Protein target modulation

Where OncoArendi Therapeutics is headquartered

Location

Headquarters

HQ city
Wysokie Mazowieckie
HQ country
Poland
HQ region
Europe

Markets served

OncoArendi Therapeutics business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Personnel, Technology or R&D, Operations, Marketing or Sales, Others

Distribution channels1 record

Marketing channels4 records

OncoArendi Therapeutics product offering

Product offering

Core offering

Molecure (formerly OncoArendi Therapeutics) discovers and develops first-in-class small molecule drugs for the treatment of neoplastic, inflammatory, and fibrotic diseases with unmet medical need. Its core pipeline comprises clinical-stage drug candidates OATD-01 and OATD-02, supported by an in-house medicinal chemistry and biology discovery capability and a small molecule mRNA targeting discovery platform that identifies and validates novel protein and mRNA targets.

Product overview

Molecure (formerly OncoArendi Therapeutics) is an innovative biotechnology company discovering, developing, and commercializing novel therapeutics for neoplastic and inflammatory diseases. The company operates a diversified pipeline consisting of clinical-stage programs OATD-01 and OATD-02 for inflammatory and fibrotic diseases, alongside a cutting-edge small molecule mRNA targeting discovery platform. The company utilizes its in-house medicinal chemistry and biology capabilities to identify and validate unexplored protein and mRNA targets, modulating their activity with first-in-class small molecule drugs. The pipeline also includes discovery-stage protein target programs. In 2026, the company announced closure of its RNA program to focus on the most commercially promising projects.

Differentiator

Problem solved

Functional benefit

Products and services

  • OATD-01 A clinical-stage drug candidate targeting inflammatory and fibrotic diseases, forming part of Molecure's focused therapeutic strategy for diseases with significant unmet medical need.
  • OATD-02 A clinical-stage drug candidate for inflammatory and fibrotic diseases, part of Molecure's core clinical portfolio alongside OATD-01.

Companies that use OncoArendi Therapeutics

Customer profile

Segments1 record

Ideal customer profiles1 record

OncoArendi Therapeutics technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Feature3 records

OncoArendi Therapeutics partnerships and signals

Strategic signal

Scale indicators2 records

Recent moves7 records

Expansion highlights4 records

OncoArendi Therapeutics competitors and assessment

Company assessment

Direct peers

  • Evotec SE: German drug discovery and development company with a similar model of medicinal chemistry-driven small molecule discovery partnerships; comparable in scale and pre-clinical/early-clinical focus.
  • Zealand Pharma: Danish clinical-stage biotech developing innovative therapeutics including small molecules and peptides; comparable European biotech with similar pipeline-stage profile.
  • Galapagos NV: Belgian clinical-stage biotech focused on small molecule drug discovery in inflammatory and fibrotic diseases, with comparable pipeline depth and European listing (Nasdaq/AMS).
  • PureTech Health: UK-listed biotech developing first-in-class therapeutics, often in inflammatory and fibrotic disease, with a similar model of platform-driven drug discovery.

Broad incumbents

  • Orion Corporation: Finnish pharmaceutical company active in small molecule drug development, including specialty and inflammatory disease areas; broader portfolio but overlapping therapeutic focus.
  • Recordati S.p.A. Italian specialty pharma with established inflammatory and rare disease franchises; comparable EU pharma peer with small molecule capabilities.

Emerging players

  • Silence Therapeutics: UK biotech developing RNA-targeting therapeutics (siRNA); directly relevant as a peer in the small-molecule-RNA targeting space Molecure exited in 2026.
  • AbCellera Biologics: Public clinical-stage biotech developing therapeutic antibodies; different modality but comparable mid-stage clinical pipeline and discovery platform orientation.
  • Schrödinger, Inc. US computational chemistry/molecular modeling platform for small molecule drug discovery; comparable computational-discovery angle and peer for Molecure's cheminformatics approach.

Regional players

  • Celon Pharma S.A. Polish clinical-stage biotech listed on the WSE developing small molecule drugs; comparable Central European peer in size, listing venue, and clinical-stage focus.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks5 records

Key highlights6 records

Customer concentration

OncoArendi Therapeutics social profiles

Digital presence

OncoArendi Therapeutics financial estimates

Financial estimate

Revenue estimate

Valuation estimate

OncoArendi Therapeutics leadership team

Management profile

Number of profiles

Profiles3 records

OncoArendi Therapeutics funding detail

Funding detail

Funding overview

Funding rounds5 records

Investors3 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

OncoArendi Therapeutics M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about OncoArendi Therapeutics

What does OncoArendi Therapeutics do?

Molecure (formerly OncoArendi Therapeutics) discovers and develops first-in-class small molecule drugs for the treatment of neoplastic, inflammatory, and fibrotic diseases with unmet medical need. Its core pipeline comprises clinical-stage drug candidates OATD-01 and OATD-02, supported by an in-house medicinal chemistry and biology discovery capability and a small molecule mRNA targeting discovery platform that identifies and validates novel protein and mRNA targets.

Is OncoArendi Therapeutics a public or private company?

OncoArendi Therapeutics is a private company. It is classified as public and is currently operating.

When was OncoArendi Therapeutics founded?

OncoArendi Therapeutics was founded in 2012. It employs 51 to 100 people.

Where is OncoArendi Therapeutics based?

OncoArendi Therapeutics is headquartered in Wysokie Mazowieckie, Poland, in the Europe region.

Who are OncoArendi Therapeutics's main competitors?

Direct peers on record are Evotec SE, Zealand Pharma, Galapagos NV and PureTech Health. Broad incumbents are Orion Corporation and Recordati S.p.A.. Emerging players are Silence Therapeutics, AbCellera Biologics and Schrödinger, Inc.. Celon Pharma S.A. is listed as a regional player.

Does OncoArendi Therapeutics have an API?

No public API is recorded for OncoArendi Therapeutics.

What industry is OncoArendi Therapeutics in?

OncoArendi Therapeutics's product category is Clinical-stage Drug Discovery. Its primary akta.pro industry code is HLAIALAA, Drug Discovery (Target ID/Validation & Hit Discovery), with a secondary code of HLAAAIAI, Target Identification & Validation Platforms (omics-driven, chemoproteomics, genetic validation). Its NAICS code is 325412 and its SIC code is 2834.

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Live signals
PR NewswireOncoArendi Therapeutics Reports Continued Strategic and Operational Momentum for 12 Months ended 31 December 2021OncoArendi Therapeutics, a Polish clinical-stage biopharmaceutical company, reported its 2021 full-year results showing a net loss of PLN13.64 million compared to a profit of PLN64.27 million in 2020, primarily due to a one-time US$28 million upfront payment received from Galapagos in 2020. The company achieved key operational milestones including a strategic partnership with the International Institute of Molecular and Cell Biology in Warsaw to accelerate its small molecule RNA platform and completed preclinical development of OATD-02, a first-in-class dual arginase inhibitor scheduled to begin Phase 1/2 clinical trials in the second half of 2022. OncoArendi's cash position of PLN102 million is expected to fund operations into Q4 2023, with Galapagos advancing the licensed compound GLPG4716 toward Phase 2 studies.PR NewswireOncoArendi Therapeutics Announces a License Option Agreement with University of MichiganOncoArendi Therapeutics S.A. announced it has entered into an option-to-license agreement with Innovation Partnerships at the University of Michigan to develop novel small molecule inhibitors targeting fibrotic diseases, including pulmonary fibrosis. The novel inhibitors were initially generated and validated through a research collaboration with Michigan State University, with U-M entering the agreement on behalf of both U-M and MSU. OncoArendi will confirm certain properties of the selective small molecule inhibitors and then have the option to obtain exclusive worldwide license rights to these compounds.PR NewswireOncoArendi Therapeutics Appoints Dr. Adam Gołębiowski, Dr. Zbigniew Zasłona and Agnieszka Rajczuk-Szczepańska to its Management BoardOncoArendi Therapeutics, a clinical-stage Polish biotechnology company listed on the Warsaw Stock Exchange, announced the appointments of Dr. Adam Gołębiowski, Dr. Zbigniew Zasłona, and Agnieszka Rajczuk-Szczepańska to its Management Board. Dr. Gołębiowski, a co-founder with over 20 years of drug discovery experience at Procter & Gamble and pharmaceutical research institutes, brings deep scientific expertise, while Dr. Zasłona, an international expert in inflammatory processes and lung diseases, currently serves as the company's Director of Biology. The appointments are intended to strengthen the board's scientific and organizational capabilities as OncoArendi continues to develop its pipeline of small molecule drugs targeting mRNA and protein disease targets, including OATD-02 expected to enter clinical development in the second half of 2022.PR NewswireOncoArendi Therapeutics Appoints Samson Fung, M.D. as Chief Medical OfficerOncoArendi Therapeutics announced the appointment of Samson Fung, M.D. as its new Chief Medical Officer, effective immediately. Dr. Fung, who brings over two decades of experience in biotech and pharma, will oversee global clinical development, translational science, regulatory strategies, and lead the advancement of OATD-02 into Phase 1 trials. The appointment comes as OncoArendi prepares to progress its pipeline of first-in-class cancer and fibrosis therapies, with OATD-02 on track to begin Phase 1 in the second half of 2022.PR NewswireOncoArendi Therapeutics supervisory board welcomes international biopharmaceutical experts: Nancy Van Osselaer, Paul van der Horst and Rafal Kamiński as its new membersOncoArendi Therapeutics, a clinical-stage Polish biotechnology company listed on the Warsaw Stock Exchange, announced the appointment of Nancy Van Osselaer, Paul van der Horst, and Rafal Kamiński to its Supervisory Board. The new board members bring over 20-25 years of combined experience in drug development, business development, and M&A transactions across leading pharmaceutical companies including Galapagos, Johnson & Johnson, UCB, and Roche. Notably, Dr. Rafal Kamiński, who previously served as OncoArendi's Chief Scientific Officer, will depart after a brief supervisory board tenure to assume the CSO role at Angelini Pharma.