Centre for Genomic Regulation

What Centre for Genomic Regulation does

The Centre for Genomic Regulation (CRG) is a Spanish non-profit biomedical research institute founded in 2000 and headquartered at the Barcelona Biomedical Research Park (PRBB). It operates four research programmes spanning bioinformatics, genome biology, cell and tissue biology, and gene regulation/stem cells/cancer, supported by a Core Technologies Programme offering genomics, proteomics, bioinformatics, advanced light microscopy, flow cytometry, and tissue engineering services. CRG produces proprietary computational tools (Geneid, AStalavista, CRISPETa, GEMtools, U12DB, Selenoprofiles, the Lifespan Machine), the Single Cell Genomics Platform for massively parallel cellular profiling, and the European Genome-Phenome Archive for secure cross-border human genetic data sharing.

The institute's commercial surface is intentionally non-monetised: CRG follows an Open Science policy (in force since April 2016) and derives its budget almost entirely from public research grants and institutional contributions from the Generalitat de Catalunya, Ministerio de Ciencia e Innovación, Universitat Pompeu Fabra, and "la Caixa" Foundation, supplemented by EU framework programme awards (Horizon 2020, ERC, EIC) and member consortium dues from BIST, SOMMa, ELIXIR, EuroBioImaging, and ISBE. Recent grant wins include €19.3M PrecisionTox, €10M ERC Synergy, €5M SYSAGING, and a record fourth ERC Advanced Grant to Luis Serrano.

Its customer base is the global scientific community served via open access publications, open-source software, training programmes for PhD students and postdoctoral researchers, and the Barcelona Collaboratorium. The institute operates a Technology and Business Development Office (TBDO) for IP transfer. Employing 501-1000 staff with Severo Ochoa excellence accreditation and HR Excellence in Research certification, CRG is positioned as a translational research platform rather than a commercial entity.

Name

Centre for Genomic Regulation

Legal name

FUNDACIO CENTRE DE REGULACIO GENOMICA

Website

https://crg.eu

Company type

Private

Founded year

2000

Operating status

Operating

Headcount range

501–1,000 employees

Short description

The Centre for Genomic Regulation (CRG) is a Barcelona-based international biomedical research institute of excellence, producing open-access genomic and computational biology research, AI/ML models, and core technology services for the global scientific community, funded primarily by public research grants.

Ownership category

akta.pro rank

Product category

Biomedical Research Services

NAICS

Scientific Research and Development Services (5417), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Clinical Data Management, Biostatistics & Statistical Programming CROs (HLAGAAAF)

akta.pro secondary industry

Central Laboratory & Clinical Trial Testing CROs (HLAGAAAE)

Keywords

• Biomedical research
• Genomic analysis
• Computational biology
• Single-cell genomics
• Life sciences training

Headquarters

HQ city

Barcelona

HQ country

Spain

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Infrastructure, Operations, Others

Revenue model

1. Public Research Funding: CRG is a publicly funded research institute receiving support from government agencies including Generalitat de Catalunya, Ministerio de Ciencia e Innovación, European Union funds, and international funding bodies. The institute has a track record of securing prestigious international public and private funding.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels6 records

Core offering

Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence that conducts fundamental and translational research in genomics, cell biology, and disease mechanisms. It provides shared scientific infrastructure (genomics, proteomics, bioinformatics, advanced imaging), develops open-source computational biology tools, manages the European Genome-Phenome Archive for human genetic data, and trains PhD students and postdoctoral researchers. Its output is disseminated through open access publications, research collaborations, and participation in pan-European research infrastructures.

Product overview

Centre for Genomic Regulation (CRG) is an international biomedical research institute offering a portfolio of research technologies, computational tools, and collaborative platforms. The core offerings include: (1) the Core Technologies Programme providing shared scientific infrastructure for genomics, proteomics, bioinformatics, and advanced imaging; (2) the European Genome-Phenome Archive (EGA) for secure human genetic data storage and sharing; (3) specialized software tools from research labs including AStalavista, Geneid, CRISPETa, and GEMtools; (4) Single Cell Genomics Platform for cellular-level genomic analysis; (5) AI/ML models including popEVE for rare disease diagnosis; and (6) the Barcelona Collaboratorium for interdisciplinary research collaboration.

Differentiator

Problem solved

Functional benefit

Products and services

• Core Technologies Programme Shared scientific infrastructure providing access to advanced research technologies including genomics, proteomics, bioinformatics, advanced light microscopy, flow cytometry, and tissue engineering services for researchers and scientific collaborators.
• European Genome-Phenome Archive (EGA) European archive service for securely storing and sharing human genetic and phenome data, enabling cross-border genomic data sharing for biomedical researchers.
• Single Cell Genomics Platform Transversal research platform providing single-cell level genomic analysis to study cellular heterogeneity in tissues and organisms, used in cancer research, stem cell biology, and gene regulation studies.
• Guigó Lab Computational Biology Tools Suite of open-source computational tools including AStalavista for alternative splicing analysis, Geneid for ab initio gene prediction, CRISPETa for CRISPR sgRNA design, GEMtools for sequence mapping, and gff2ps for genomic annotation visualization, made available to the research community.
• popEVE Deep generative AI model developed with Harvard Medical School that estimates deleteriousness of genetic variants across the proteome using evolutionary principles, supporting rare disease diagnosis.
• Barcelona Collaboratorium Collaborative platform combining scientific excellence with integration of early-career researchers through discussion sessions, networking, and community-building activities.
• Research Training Programmes Structured educational programmes for undergraduates, masters, PhD students, and postdoctoral researchers seeking training in genomics, cell biology, computational biology, and related life sciences disciplines.
• Neuroscience Resources Scientific resources and tools supporting neuroscience research at CRG and provided to the broader research community.
• PRBB μFabLab Microfabrication laboratory providing nanofabrication and prototyping capabilities to researchers across the Barcelona Biomedical Research Park (PRBB) and affiliated institutions.

Quantifiable outcome

• Roderic Guigó elected to EMBO Membership
• +2 more outcomes

Named customers2 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability14 records

Feature11 records

Partnerships

21 partnerships are on record, tiered major, core and minor.

• Shenzhen Institutes of Advanced Technology (SMART) and Shenzhen Bay Laboratory (SZBL)majorStrategic or Co-development Partner · 30 June 2026MoU signed to bring Barcelona science closer to the Guangdong-Hong Kong-Macao Greater Bay Area, fostering international research collaboration.
• Generalitat de CatalunyacoreStrategic or Co-development PartnerBoard of Trustees member providing institutional governance and support to CRG as part of the CERCA system of research institutes in Catalonia.
• Ministerio de Ciencia e InnovacióncoreStrategic or Co-development PartnerSpanish Ministry of Science and Innovation as Board of Trustees member, providing national-level governance and funding support.
• Universitat Pompeu FabracoreStrategic or Co-development PartnerUPF as founding university partner and Board of Trustees member, providing academic affiliation and collaborative research opportunities.
• "la Caixa" FoundationcoreStrategic or Co-development Partner"la Caixa" Foundation as Board of Trustees member supporting biomedical research through funding and institutional collaboration.
• Barcelona Institute of Science and Technology (BIST)coreStrategic or Co-development PartnerCRG is a member of BIST, a consortium of cutting-edge Barcelona research centers working on interdisciplinary science.
• SOMMacoreStrategic or Co-development PartnerAlliance of Severo Ochoa and María de Maeztu Excellence Centers, organizing events like SOMMa Connect.
• Barcelona Biomedical Research Park (PRBB)coreStrategic or Co-development PartnerCRG is located in and is a member of PRBB, sharing infrastructure with other biomedical research institutions.
• EU LifemajorStrategic or Co-development PartnerEuropean research infrastructure network for life sciences contributing to collaborative projects and knowledge sharing.
• Core for LifemajorStrategic or Co-development PartnerAlliance of European life science research centers facilitating collaborative research and technology sharing.
• AseBiominorStrategic or Co-development PartnerSpanish biotechnology association connecting research institutions with industry for innovation transfer.
• EMBL BarcelonamajorStrategic or Co-development PartnerEuropean Molecular Biology Laboratory Barcelona location, with James Sharpe (former CRG group leader) as Director.
• Institute for Bioengineering of Catalonia (IBEC)majorStrategic or Co-development PartnerBIST Ignite Grant collaboration to explore new ways of treating brain disorders using RNA technology.
• University of CambridgemajorStrategic or Co-development PartnerCollaboration to develop AID system for precise protein level control in C. elegans model organism for aging research.
• ELIXIRcoreStrategic or Co-development PartnerEuropean research infrastructure for life science data, with CRG participating in ELIXIR-CONVERGE and other data-related projects.
• EuroBioImagingcoreStrategic or Co-development PartnerEuropean research infrastructure for imaging technologies where CRG contributes imaging expertise and facilities.
• ISBEcoreStrategic or Co-development PartnerInfrastructure for systems biology enabling CRG participation in pan-European systems biology networks.
• IRB BarcelonamajorStrategic or Co-development PartnerBarcelona-based research institute collaboration including Toni Gabaldón affiliation and Barcelona-wide single cell data club.
• CNAG-CRGmajorStrategic or Co-development PartnerNational Center for Genomic Analysis working with CRG on Barcelona-wide single cell data club and joint research.
• Barcelona Supercomputing Center (BSC-CNS)majorStrategic or Co-development PartnerSupercomputing resources collaboration with Toni Gabaldón affiliated at BSC-CNS for computational genomics.
• EduCaixaminorStrategic or Co-development PartnerEducational foundation partner for citizen science project 'Stick your tongue out' studying mouth microbiome.

Scale indicators9 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• European Molecular Biology Laboratory (EMBL): Intergovernmental molecular biology research institute with comparable scope across genomics, bioinformatics, structural biology and training. EMBL is the most structurally analogous peer to CRG within Europe and competes with it for talent and EU funding.
• Wellcome Sanger Institute: UK-based genomics research institute with strong overlap in genome analysis, single-cell genomics, computational biology and disease-focused programs at similar headcount and funding scale.
• Broad Institute of MIT and Harvard: Major US biomedical and genomic research organization with parallel emphasis on computational biology, variant interpretation (e.g., gnomAD-like resources), single-cell analysis and AI for biology.
• Institute for Research in Biomedicine (IRB Barcelona): Barcelona-based biomedical research institute focused on molecular biology and disease mechanisms; shares location, BIST membership, and overlapping faculty collaboration (e.g., Toni Gabaldón).
• Centro Nacional de Análisis Genómico (CNAG-CRG): National genomic analysis centre co-located with CRG at the Barcelona Biomedical Research Park; sister organisation with overlapping large-scale sequencing, single-cell, and data infrastructure activities.
• Max Planck Institute for Molecular Genetics: German publicly-funded institute focused on genomics, gene regulation and computational biology — closely comparable research portfolio, public-funding model, and European institutional positioning.
• Whitehead Institute for Biomedical Research: MIT-affiliated non-profit biomedical research institute of similar headcount focused on fundamental genomics, stem cells and disease biology — close analog in mission, scale and non-profit research model.
• European Bioinformatics Institute (EMBL-EBI): EMBL's bioinformatics hub at Hinxton; close peer for CRG's bioinformatics programme, ELIXIR hosting role, and population-scale genomic data resources (similar data-infrastructure mandate).

Broad incumbents

• Institut Pasteur: Large French foundation-based biomedical research institute with comparable mix of fundamental research, training, and public funding, though broader disease scope than CRG.
• Helmholtz Centre for Infection Research (HZI): Large-scale German publicly-funded life sciences institute under the Helmholtz Association with similar research-grant-driven operating model, broader infectious-disease scope.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/CRGenomica
• LinkedInlinkedin.com/company/798595
• Facebookfacebook.com/centreforgenomicregulation

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Funding overview

Funding rounds

Investors

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M&A

Investments2 records

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Frequently asked questions about Centre for Genomic Regulation