What APEX Biologix does

APEX Biologix is a privately held U.S. medical device manufacturer founded in 2014 and headquartered in Clearwater, Florida, with a second office near Salt Lake City, Utah. The company sells FDA-registered Class II autologous biologic processing systems under the XCELL brand — including XCELL PRP (Platelet-Rich Plasma), XCELL BMC (Bone Marrow Concentrate), XCELL PC (Protein Concentrate/A2M), and XCELL PRF (Platelet-Rich Fibrin) — along with supporting capital equipment such as the Drucker Boost 4+ Flex Centrifuge, a patented Benchtop Processing Station, and a Procedure Prep Cart. APEX targets clinicians across orthopedic surgery, non-operative sports medicine, interventional pain, integrative medicine, aesthetics, and extremities, providing both the kits and a clinical education infrastructure built around a 10,000 sq. ft. XCELL Learning Center, live webinars, and the "XCELL In Practice" ongoing training program.

The company's core technology is a closed-loop, hardware-based biologic processing platform with FDA 510(k) clearances on the PRP system, Drucker centrifuge, and the patented benchtop processing station (which provides integrated lighting and an intuitive dial for consistent buffy coat capture with minimal red blood cell contamination). Performance claims versus predicate devices include up to 10x platelet concentration over baseline, 83% average platelet recovery, an average 10.8 billion platelet dose, greater than 80% recovery of nucleated white cells from bone marrow aspirate, and Protein Concentrate A2M levels 5x higher than standard PRP and 1.2x higher than predicate devices, with 67% more efficient water removal. The product set is designed as an integrated ecosystem: kits, centrifuge, and processing station are engineered to interoperate, encouraging standardization across a practice's regenerative medicine procedures.

Commercially, APEX operates a sales-led GTM combining direct quote-based sales to clinicians and physicians with a formal distributor program ("Become a Distributor"). Pricing is not publicly disclosed and is negotiated on a quote basis. Revenue is generated through hardware sales of single-use kits and durable equipment, supported by recurring kit consumption per procedure. The company augments product sales with a substantial medical education function — including a dedicated SVP of Medical Education, vertical-specific managers for extremities, chiropractic, integrative/functional medicine, and PM&R, and a Translational Research VP — indicating that training and clinical evidence generation are core to its go-to-market rather than ancillary services. APEX served a 2014 founding cohort of customers in regenerative medicine and has since expanded into a multi-vertical U.S. business; a 2022-11-30 funding event with Three Bridges Private Capital was recorded, though no revenue or transaction value is disclosed.

Name

APEX Biologix

Legal name

APEX Biologix

Website

https://apexbiologix.com

Company type

Private

Founded year

2014

Operating status

Operating

Headcount range

11–50 employees

Short description

APEX Biologix is a privately held U.S. manufacturer of FDA-cleared XCELL autologous biologic processing systems (PRP, BMC, PC, PRF) and supporting equipment, selling direct and via distributors to clinicians across orthopedic, sports medicine, pain, aesthetics, and integrative medicine practices.

Ownership category

akta.pro rank

Product category

Regenerative Medicine Medical Devices

NAICS

Surgical and Medical Instrument Manufacturing (339112), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510), Medical Equipment and Supplies Manufacturing (3391)

SIC

Surgical & Medical Instruments & Apparatus (3841), Electromedical & Electrotherapeutic Apparatus (3845)

akta.pro primary industry

Cell Therapy Manufacturing Services (GMP, autologous/allogeneic) (HLAAAKAC)

akta.pro secondary industry

Training & Competency Programs for GxP Compliance (HLAGAKAM)

Keywords

• Autologous biologic systems
• Platelet-rich plasma kits
• Bone marrow concentrate
• Regenerative medicine devices
• Protein concentrate systems

Headquarters

HQ city

Clearwater

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Personnel, Supply Chain, Technology or R&D, Marketing or Sales

Revenue model

1. Biologic Processing Systems and Kits: APEX Biologix generates revenue through the sale of FDA-registered Class II medical devices including XCELL PRP kits, XCELL BMC kits, and XCELL Protein Concentrate kits. The company also sells associated equipment including centrifuges, benchtop processing stations, and procedure prep carts. Sales appear to be direct to clinicians and through distributor networks.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels7 records

Core offering

APEX Biologix designs, manufactures, and distributes FDA-registered Class II autologous biologic processing systems under the XCELL platform brand, including XCELL PRP (Platelet-Rich Plasma), XCELL BMC (Bone Marrow Concentrate), XCELL PC (Protein Concentrate/A2M), and XCELL PRF (Platelet-Rich Fibrin) kits, along with supporting accessories such as the Drucker Boost 4+ Flex Centrifuge, patented Benchtop Processing Station, and Procedure Prep Cart. The company sells these medical devices directly to clinicians and medical practices across orthopedics, sports medicine, interventional pain, integrative medicine, and aesthetics, complemented by clinical education, training, and practice integration services delivered through the XCELL Learning Center and XCELL In Practice program.

Product overview

APEX Biologix is a regenerative medicine company offering a comprehensive portfolio of FDA-registered Class II autologous biologic systems, forming the XCELL platform. The core portfolio consists of XCELL PRP (Platelet-Rich Plasma), XCELL BMC (Bone Marrow Concentrate), XCELL PC (Protein Concentrate/A2M), and XCELL PRF (Platelet-Rich Fibrin). These products are designed for precision, efficiency, and reproducibility to optimize biologic yield across orthopedics, sports medicine, interventional pain, integrative care, and aesthetics. The platform is supported by specialized accessories including the Drucker Boost 4+ Flex Centrifuge, Benchtop Processing Station, and Procedure Prep Cart. The XCELL PRP and PC systems process blood to produce therapeutic concentrates, while XCELL BMC processes bone marrow aspirate for MSC concentration. All systems are engineered to work together as an integrated biologic processing ecosystem.

Differentiator

Problem solved

Functional benefit

Brands

• XCELL: Product line brand for autologous biologic processing systems including XCELL PRP (Platelet-Rich Plasma), XCELL BMC (Bone Marrow Concentrate), XCELL PC (Protein Concentrate), and related equipment like centrifuges and benchtop processing stations.

Products and services

• XCELL PRP (Platelet-Rich Plasma) System FDA 510(k)-approved Platelet-Rich Plasma (PRP) processing system with patented benchtop processing station that enables customizable leukocyte concentrations and output volume, achieving up to 10x platelet concentration over baseline and 83% average platelet recovery. Designed for clinicians across orthopedics, sports medicine, interventional pain, primary care, and aesthetics.
• XCELL BMC (Bone Marrow Concentrate) System Bone Marrow Concentrate system designed to maximize mesenchymal stem cell (MSC) count, achieving greater than 80% recovery of nucleated white cells and 5x enrichment over baseline bone marrow aspirate levels. Used by orthopedic and sports medicine physicians for regenerative procedures.
• XCELL PC (Protein Concentrate) System Protein Concentrate system that captures beneficial proteins including A2M (Alpha-2-macroglobulin), IL-1ra, sTNF, and PDGF-BB from platelet-poor plasma. Removes 67% more water than predicate devices, delivers 5x more A2M concentration than standard PRP, and 1.2x higher A2M than predicate devices. Targeted at interventional pain and orthopedic use cases.
• XCELL PRF (Platelet-Rich Fibrin) System Platelet-Rich Fibrin system for regenerative medicine applications, part of the XCELL platform family, used by clinicians for autologous fibrin-based therapies.
• Drucker Boost 4+ Flex Centrifuge FDA 510(k)-approved centrifuge specifically engineered for XCELL PRP and BMC processing, with pre-programmed cycles, auto-locking lid, up to 15% quieter operation, 6 brake settings, fast abort function, max RCF 3,000, and a 2-year parts and labor warranty. Manufactured to ISO13485-compliant specifications.
• Procedure Prep Cart Extra Wide Core Cart with white drawers for storing and mobilizing biologic procedure supplies, with large work surface, HDPE plastic construction, clear PETG door, 3 white locking drawers, 1 locking bulk storage area, 3-inch casters, and storage for up to 25 kits. Lifetime guarantee, made in the USA.
• Benchtop Processing Station Patented processing station with integrated lighting, stable base, and intuitive dial for consistent, precise buffy coat capture with minimal red blood cell contamination. 510(k) Class II compliant, sold as a standalone accessory for the XCELL PRP workflow.

Quantifiable outcome

• Up to 10x platelet concentration over baseline with XCELL PRP system
• +5 more outcomes

Named customers3 records

Segments6 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Scale indicators6 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Emcyte Corporation: Emcyte is a direct competitor in autologous PRP and stem-cell concentrate kits for regenerative medicine, offering comparable point-of-care biologic processing systems and accessories for orthopedic and aesthetic practices.
• Royal Biologics: Royal Biologics sells orthobiologic and regenerative medicine kits (including PRP and BMC) directly to orthopedic and pain specialists, mirroring APEX's product offering and customer base.
• Isto Biologics: Isto Biologics provides autologous biologic solutions (including bone marrow concentrate and platelet-rich plasma kits) for orthopedic and spine applications, overlapping with APEX's XCELL BMC and PRP offerings.
• Celling Biosciences: Celling Biosciences develops autologous point-of-care cell therapy processing systems, including bone marrow concentrate devices, positioning it as a direct competitor to APEX's XCELL BMC platform.

Broad incumbents

• Arthrex: Arthrex is a dominant orthopedic surgical device maker whose Autologous Conditioned Plasma (ACP) system competes directly with XCELL PRP in sports medicine and orthopedic channels, backed by a far larger sales infrastructure.
• Stryker: Stryker is a large orthopedic and medical device incumbent with biologic and surgical offerings that compete for the same hospital and surgical-center budgets as APEX's regenerative medicine kits.
• Zimmer Biomet: Zimmer Biomet is a global orthopedic device leader with regenerative medicine and biologics offerings, competing with APEX in the orthopedic and sports medicine channels where both companies sell.
• Terumo BCT: Terumo BCT is a leading blood and cell processing technology company whose centrifuges and closed-system processing devices overlap with APEX's Drucker centrifuge and XCELL processing platform.

Emerging players

• Regenexx: Regenexx is a regenerative medicine clinic network and procedural technology provider that uses autologous biologics, positioning it as an emerging player in the same orthobiologics space where APEX sells kits.

Others

• Drucker Diagnostics: Drucker Diagnostics manufactures the centrifuges (including the Boost 4+ Flex) used by APEX, making it an enabling equipment partner and adjacent supplier within the same regenerative medicine workflow.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/Apex_Biologix
• Facebookfacebook.com/apexbiologix
• LinkedInlinkedin.com/company/apex-biologix

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about APEX Biologix