UCI Health

What UCI Health does

UCI Health is the clinical enterprise of the University of California, Irvine, operating as a non-profit academic health system since 1976. It serves approximately 5.6 million people across Orange County, western Riverside County, and southeast Los Angeles County through 1,461 licensed beds, a network of ambulatory care centers, and a clinically integrated physician network. The system is anchored by UCI Medical Center in Orange — the only NCI-designated comprehensive cancer center in Orange County, a Level I adult and Level II pediatric trauma center, a regional burn center, and a gold-level 1 geriatric emergency department — alongside a newly opened $1.3 billion, 144-bed all-electric acute care hospital in Irvine.

The system's core offerings span tertiary and quaternary clinical care across oncology, cardiology, neurology, orthopaedics, digestive health, dermatology, and primary care, complemented by clinical trials, research programs (including CIRM-funded regenerative medicine), and digital channels such as OnCall Virtual Visits. Technology assets include AI-powered smart room patient engagement deployed at the Irvine campus (GW RhythmX Get Well platform), the FLAME multiphoton exoscope for non-invasive melanoma detection (in clinical trials), and a co-development partnership with TRUE-See and UC Irvine's A2IR center for AI-driven wound care and dermatology decision support.

UCI Health generates revenue primarily through patient care services reimbursed by commercial insurance, Medicare, and Medicaid, supplemented by clinical research grants and managed services through its clinically integrated physician network. Following its March 2024 acquisition of four Tenet Healthcare hospitals and the December 2025 Irvine campus opening, the system now operates a multi-site, multi-county footprint. Recent leadership changes — including Dr. Michael J. Stamos's appointment as interim Vice Chancellor of Health Affairs and a workforce restructuring tied to federal funding and reimbursement shifts — reflect the system's transition from regional expansion into integrated multi-site operating discipline.

Name

UCI Health

Legal name

The Regents of the University of California

Website

https://ucihealth.org

Company type

Public

Founded year

1976

Operating status

Operating

Headcount range

5,001–10,000 employees

Short description

UCI Health is the academic health system of the University of California, Irvine, operating 1,461 licensed beds across Orange and Los Angeles counties and serving 5.6 million people in Southern California with tertiary, quaternary, and oncology care.

Ownership category

akta.pro rank

Product category

Academic Healthcare Services

NAICS

General Medical and Surgical Hospitals (6221), Specialty (except Psychiatric and Substance Abuse) Hospitals (622310), Ambulatory Health Care Services (621)

SIC

Services-General Medical & Surgical Hospitals, Nec (8062), Services-Specialty Outpatient Facilities, Nec (8093)

akta.pro primary industry

Hospital-Integrated Cancer Centers (Acute Oncology Programs) (HLAFAAAM)

Keywords

• Academic medical center
• Healthcare services
• Cancer care
• Emergency medicine
• Clinical research

Headquarters

HQ city

South Orange

HQ country

United States

HQ region

North America

Offices13 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Technology or R&D, Supply Chain, Marketing or Sales

Revenue model

1. Patient Care Services: Direct patient care services including primary care, specialty care, tertiary/quaternary care, emergency services, and surgical procedures. Revenue generated through insurance reimbursements, Medicare/Medicaid, and patient payments.
2. Clinical Research and Grants: Revenue from clinical trials and research grants. UCI Health conducts clinical trials including regenerative medicine studies funded by organizations like the California Institute for Regenerative Medicine (CIRM).
3. UCI Health Physician Network: A clinically integrated network encompassing primary care and specialty services, fostering physician-led partnerships between UCI Health and external physician practices.

Go-to-market motion1 record

Distribution channels4 records

Marketing channels6 records

Core offering

UCI Health is an academic health system that delivers tertiary and quaternary hospital care, specialty clinical services, and emergency medicine across 1,461 licensed inpatient beds in Southern California. It operates the only National Cancer Institute-designated comprehensive cancer center in Orange County, along with Level I adult and Level II pediatric trauma centers, a regional burn center, and a network of ambulatory clinics. The organization also conducts clinical research and clinical trials as part of its affiliation with UC Irvine.

Product overview

UCI Health is a multi-site academic healthcare system comprising 1,461 inpatient beds across its main campus in Orange, a new 144-bed all-electric acute care hospital campus in Irvine opened in December 2025, and four acquired community hospitals from Tenet's Pacific Coast Network (adding 858 beds in Orange and Los Angeles counties). The system offers a broad range of medical specialties including cancer care (the only NCI-designated comprehensive cancer center in Orange County), cardiology, dermatology, digestive health, neurology, neurosurgery, orthopaedics, and primary care, along with a network of ambulatory care centers. UCI Health serves 5.6 million people across Orange County, western Riverside County, and southeast Los Angeles County. Key facilities include UCI Medical Center (flagship), UCI Health — Irvine (new AI-enabled campus), Joe C. Wen & Family Center for Advanced Care, and the Gavin Herbert Eye Institute. Technology offerings include the GW RhythmX Get Well AI-powered patient engagement platform (smart rooms, personalized care) deployed at the Irvine campus, and the FLAME laser diagnostic device for melanoma detection in clinical trials. UCI Health also operates the UCI Health Physician Network, a clinically integrated network of affiliated community physicians and practices.

Differentiator

Problem solved

Functional benefit

Products and services

• UCI Medical Center UCI Health's flagship hospital in Orange, CA, providing tertiary and quaternary care. Home to the only Orange County-based National Cancer Institute-designated comprehensive cancer center, high-risk perinatal/neonatal program, Level I adult and Level II pediatric trauma center, gold level 1 geriatric emergency department, and regional burn center.
• UCI Health - Irvine Acute Care Hospital A new 350,000-square-foot, 144-bed acute care hospital campus in Irvine, CA, integrating AI-powered smart room technology and personalized care tools through the GW RhythmX Get Well patient engagement platform.
• UCI Health Community Network Hospitals Four hospitals acquired from Tenet Healthcare in March 2024, providing acute care services across Orange and Los Angeles counties: UCI Health - Fountain Valley, UCI Health - Lakewood, UCI Health - Los Alamitos, and UCI Health - Placentia Linda.
• UCI Health Cancer Center The only Orange County-based National Cancer Institute-designated comprehensive cancer center, providing advanced cancer treatments and clinical trials.
• Joe C. Wen & Family Center for Advanced Care A multi-specialty outpatient care center at UCI Health - Irvine providing advanced care across multiple specialties.
• UCI Health Gavin Herbert Eye Institute A dedicated eye care institute providing ophthalmology services at the UCI Health - Irvine campus.
• UCI Health Physician Network A collaborative partnership between UCI Health and select community physicians and practices, supporting care coordination and value-based care delivery. Affiliates include Cancer and Blood Specialty Clinic, United Medical Doctors, Associated Gastroenterology Medical Group, Southland Neurologic Institute, Coury & Buehler Physical Therapy, and California Rehabilitation & Sports Therapy.
• UCI Health Senior Health Services Geriatric care services including senior health assessments and coordination of care for older adults.
• UCI Health SeniorHealth Center Dementia Care Model The UCI Health SeniorHealth Center was selected to test a new dementia care model, providing specialized services for patients with dementia.
• OnCall Virtual Visits Virtual urgent care, same-day care, and virtual appointments for patients seeking remote consultations.

Quantifiable outcome

• 22% reduction in 30-day readmissions and 63% reduction in hospital-acquired infections
• +1 more outcomes

Named customers1 record

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Seven partnerships are on record, tiered core, minor and strategic.

• GW RhythmX (Get Well / RhythmX AI)coreTechnology or Integration · 29 January 2026GW RhythmX, formed from the merger of Get Well and RhythmX AI, deployed its Get Well patient engagement solution including Smart Room technology at the new $1.3 billion UCI Health — Irvine campus. The technology platform aims to improve patient outcomes, reduce 30-day readmissions by 22% and hospital-acquired infections by 63% based on comparable deployments.
• Aesthetics, Inc.minorStrategic or Co-development Partner · 24 November 2025Aesthetics, Inc. and UCI Health launched a comprehensive art program at the new Irvine medical campus to enhance patient and community well-being through artwork inspired by local nature and culture. The program includes over 1,465 artworks created by more than 200 regional artists.
• TRUE-See and Center for Applied AI Research at UC IrvinestrategicStrategic or Co-development Partner · 17 September 2025TRUE-See announced a strategic partnership with Dr. Peter D. Chang and the Center for Applied AI Research (A2IR) at UC Irvine. Over 18 months, the partners will curate datasets, develop AI models, and pilot decision support tools for wound care, dermatology, and plastic surgery within UCI Health's clinical workflows. TRUE-See brings a database of over 2 million color-calibrated medical photographs.
• Lifepoint RehabilitationcoreStrategic or Co-development Partner · 1 January 2022UCI Health Rehabilitation Hospital is a joint venture partnership between UCI Health and Lifepoint Rehabilitation, announced in 2022 and expected to open in 2025. The facility features specialized acquired brain injury unit, dialysis suite, imaging suite, multidisciplinary therapy gymnasiums, and outdoor courtyards.
• Rady Children's Health (formerly Children's Hospital of Orange County)strategicStrategic or Co-development PartnerUCI Health and Rady Children's Health have worked closely together for more than 25 years to provide pediatric care. The affiliation forms a strategic alliance for pediatric physicians, services, academic education, and research. Both institutions are jointly designated as a National Organization for Rare Disorders (NORD) Rare Disease Center of Excellence.
• UCI Health Physician Network AffiliatescoreChannel Partner/ Reseller/ DistributorThe UCI Health Physician Network is a clinically integrated network encompassing primary care and specialty services. Current affiliates include: Cancer and Blood Specialty Clinic, United Medical Doctors, Associated Gastroenterology Medical Group, SoCal Eye, Orange County Urology Associates, Coury & Buehler Physical Therapy, California Rehabilitation & Sports Therapy, and Southland Neurologic Institute.
• Hyundai Motor America and Hyundai Hope on WheelsminorStrategic or Co-development PartnerHyundai's partnership with UCI Health expanded car seat safety programs and preventive healthcare access for underserved families in Orange County, California. The partnership earned multiple awards including a 2026 Merit Award Gold in Corporate Responsibility and 2025 Pinnacle Awards for business.

Scale indicators9 records

Recent moves10 records

Expansion highlights6 records

Direct peers

• Cedars-Sinai Medical Center: Large academic health system serving the Los Angeles region with comprehensive tertiary/quaternary care, an NCI-designated cancer program, and extensive research infrastructure. Directly comparable to UCI Health in scope, academic mission, and competitive overlap in Southern California.
• UCLA Health: University of California, Los Angeles academic health system operating multiple hospitals and ambulatory sites with NCI-designated cancer care, research, and a broad tertiary referral base. Comparable to UCI Health as a fellow UC-system academic health system with overlapping clinical and research capabilities.
• Keck Medicine of USC: University of Southern California's academic health system providing tertiary and quaternary care in Los Angeles, including cancer care and clinical research. Comparable to UCI Health as a competing academic medical center in the Southern California market.
• Hoag Memorial Hospital Presbyterian: Major Orange County-based health system providing tertiary care and competing directly with UCI Health in the Irvine and coastal Orange County market. Comparable as a non-profit regional system with overlapping specialty services and patient demographics.
• Stanford Health Care: Quaternary academic medical center in Northern California with NCI-designated cancer care, advanced research, and high-acuity case mix. Comparable to UCI Health in academic mission and clinical-trial leadership, though operating in a different catchment.

Broad incumbents

• Providence Southern California: Large multi-state Catholic health system with multiple hospitals across Southern California, including Orange County. Comparable to UCI Health as a regional incumbent competing for the same patient population across general and specialty services.
• Kaiser Permanente Southern California: Integrated payer-provider system with a dominant Southern California footprint and closed-network care model. Comparable to UCI Health as a major regional competitor for patient lives, though operating a fundamentally different integrated-delivery business model.

Regional players

• Sharp HealthCare: Largest private health system in San Diego County with multiple acute care hospitals and a broad ambulatory network. Comparable to UCI Health as a California-based, multi-site regional academic-affiliated health system competing for similar patient segments.
• Scripps Health: San Diego-based non-profit health system with multiple hospitals, clinical research programs, and a strong specialty care portfolio. Comparable to UCI Health as a California non-profit multi-hospital system with academic affiliations and research activity.

Emerging players

• Loma Linda University Health: Academic health system affiliated with Loma Linda University providing tertiary care and clinical research in the Inland Empire. Comparable to UCI Health as a California academic health system with overlapping reach into the Riverside/San Bernardino patient market.

Market position

Strengths5 records

Weaknesses4 records

Competitive moat6 records

Key risks6 records

Key highlights6 records

Customer concentration

• Facebookfacebook.com/UCIrvineHealth
• LinkedInlinkedin.com/company/uc-irvine-medical-center
• Instagraminstagram.com/ucihealth
• Xx.com/ucirvinehealth

Compliance8 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Subsidiaries5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A4 records

Investments1 record

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about UCI Health