What Splash Clinical does

Splash Clinical is a private U.S.-based clinical trial enrollment services company headquartered in Wauwatosa, Wisconsin. Founded in 2016, the firm serves pharmaceutical sponsors, contract research organizations (CROs), and individual study sites with end-to-end patient recruitment, pre-screening, and retention services for global clinical trials. The company operates across more than 30 countries with multilingual capabilities and has facilitated over 875 studies spanning every major therapeutic category, delivering 250,000+ quality patient referrals to 5,500+ sites.

The company's technology stack centers on a suite of proprietary platforms, including the Patient Recruitment Platform (PRP) with real-time analytics, a Virtual Waiting Room (vWR) for patient engagement, Site Recruitment Solutions, Site Engagement Services, and an in-house Engagement Center call center. Its most recent product, SplashBIO™, launched in June 2025, integrates blood-based biomarker testing into pre-screening to reduce screen failure rates and is supported by strategic partnerships with C2N Diagnostics (Alzheimer's, March 2025) and Cambridge Cognition (CNS, September 2024). Supporting modules include a Patient Scheduler, Patient Concierge, At-Home Health Testing kit fulfillment, a Pre-Enrollment Registry, and a Facebook-approved Comment Manager App for adverse-event risk mitigation. The firm emphasizes integration between its recruitment systems and sponsor/site workflows as a core differentiator.

Splash Clinical monetizes through project-based fees for digital recruitment campaigns, biomarker pre-screening, patient retention services, and site engagement support, all priced on a quote basis tailored to study requirements. Its go-to-market relies on direct enterprise sales to large pharma and biotech sponsors and CROs, supplemented by inside-sales handling via a project request form. The company is privately held as SPLASH CLINICAL LLC with no disclosed venture-capital or private-equity backing; a BizTimes Milwaukee article in 2023 cited a 429% revenue growth rate over the prior three years, indicating strong organic scaling without external capital.

Name

Splash Clinical

Legal name

SPLASH CLINICAL LLC

Website

https://splashclinical.com

Company type

Private

Founded year

2016

Operating status

Operating

Headcount range

11–50 employees

Short description

Splash Clinical is a private digital and social marketing agency offering patient and site recruitment services for clinical trial enrollment, serving pharmaceutical sponsors, CROs, and study sites globally.

Ownership category

akta.pro rank

Product category

Clinical Trial Patient Recruitment Services

NAICS

Medical and Diagnostic Laboratories (62151), Medical and Diagnostic Laboratories (6215)

SIC

Services-Health Services (8000), Services-Medical Laboratories (8071)

akta.pro primary industry

Clinical Trial Patient Recruitment & Retention (HLAGACAD)

akta.pro secondary industries

Patient Recruitment, Site Feasibility & Trial Enablement CROs (HLAGAAAI), Clinical Trial Sample Collection & Site Phlebotomy Services (HLAGACAJ), Liquid Biopsy Biomarkers (ctDNA/ctRNA/CTCs/exosomes) (HLAAAMAH)

Keywords

• Clinical trial recruitment
• Patient enrollment services
• Biomarker pre-screening
• Clinical study site support
• Patient retention solutions

Headquarters

HQ city

Wauwatosa

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Clinical Trial Patient Recruitment Services: Project-based fees for digital recruitment campaigns, patient referrals, and enrollment services for pharmaceutical sponsors and CROs conducting clinical trials.
2. SplashBIO™ Biomarker Platform Services: Biomarker testing and pre-screening services integrated into clinical trial recruitment, providing qualified patients to study sites.
3. Patient Retention Services: Direct-to-patient retention communication services including branded emails, phone calls, and survey capabilities to reduce discontinuations.
4. Site Engagement Services: Per-site support services including recruitment platform access, training, and performance monitoring.

Go-to-market motion3 records

Distribution channels3 records

Marketing channels8 records

Core offering

Splash Clinical provides digital patient recruitment, engagement, and retention services for clinical trial enrollment on behalf of pharmaceutical sponsors, contract research organizations (CROs), and clinical study sites. The company delivers an integrated platform—centered on its proprietary SplashBIO™ biomarker pre-screening system, the Patient Recruitment Platform (PRP), Virtual Waiting Room, Engagement Center, and Retention Solutions—to identify, screen, and retain qualified trial participants across 30+ countries.

Product overview

Splash Clinical is a clinical trial enrollment company offering an integrated platform of proprietary recruitment, engagement, and retention solutions. The core portfolio centers on SplashBIO™ (biomarker pre-screening platform), the Patient Recruitment Platform with real-time analytics, Virtual Waiting Room, Engagement Center (call center with scheduling tools), Site Recruitment Solutions, Site Engagement Services, and Retention Solutions. Supporting modules include the Patient Scheduler App, Patient Registry, Patient Concierge, Phone Screening, Comment Manager App, and At-Home Health Testing. The company also publishes Patient Insights and Study Site Insights research reports. All solutions are designed to work together, combining digital recruitment, targeted pre-screening, patient engagement, and data analytics to deliver qualified patients from pre-enrollment through trial completion.

Differentiator

Problem solved

Functional benefit

Brands

• SplashBIO™: A proprietary biomarker platform for clinical trials that uses biomarker tests to accelerate enrollment, save money, and reduce screen failure rates. Integrates targeted recruitment with blood-based biomarker testing for pre-screening.

Products and services

• SplashBIO™ Biomarker Platform Biomarker pre-screening platform that integrates blood-based biomarker testing into clinical trial enrollment to reduce screen failure rates and deliver trial-ready patients to study sites; intended for pharmaceutical sponsors and CROs running complex inclusion-criteria trials.
• Patient Recruitment Platform (PRP) Proprietary platform enabling real-time analytics tracking and study-specific patient-facing websites, where sites can access prequalified patient referrals via a secure patient portal supporting complex prescreeners.
• Virtual Waiting Room (vWR) Enrollment-funnel supplement allowing qualified prospective participants not yet ready to screen to consent to remain engaged via scheduled communications until they or the sites are ready.
• Recruitment Analytics In-depth campaign performance analysis and progress tracking providing real-time analytics to monitor campaign objectives with frictionless tracking for quick problem resolution.
• Site Recruitment Solutions (SRS) Digital patient recruitment campaign customized for individual study sites with secure referral software targeting qualified people by specific location, age, gender, and other demographics.
• Site Engagement Services (SES) Platform and process including on-boarding, training, and support to improve site engagement in campaigns, monitoring prequalified referrals and enrollment rates per study site.
• Engagement Center (Direct to Patient Call Center) Custom call center combining technology and a patient-centric approach with site-by-site flexibility, customized schedules, and communication scripts for patient outreach and follow-up.
• Digital Recruitment Solutions Technology-powered recruitment solutions delivering qualified patients across global markets through targeted multichannel campaigns with therapeutic expertise.
• Pre-Enrollment Solutions Pre-trial planning solutions bridging the gap between trial planning and enrollment with patient registry, pre-trial surveys, and seamless transition to enrollment; provides data-driven insights and trial-ready patient cohorts.
• Global Retention Solutions Direct-to-patient retention services including branded communications, education, study-specific reminders, and retention optimization reporting to reduce discontinuations and dropouts across global programs.
• At-Home Health Testing Laboratory-grade saliva testing kit fulfillment service with in-house packaging, shipping, and warehouse solutions customized per study requirements to support remote screening.

Quantifiable outcome

• Splash Clinical campaign generated 28% of total randomizations in Global Cardiovascular Disease study across 13 countries
• +8 more outcomes

Named customers3 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature10 records

Partnerships

Two partnerships are on record, tiered core.

• C2N DiagnosticscoreStrategic or Co-development Partner · 25 March 2025Splash Clinical and C2N Diagnostics partnered to enhance recruitment for Alzheimer's disease clinical trials. The partnership combines Splash's proprietary recruitment infrastructure with C2N's PrecivityAD2™ blood tests to improve patient identification and pre-screening for Alzheimer's trials globally.
• Cambridge CognitioncoreStrategic or Co-development Partner · 6 September 2024Splash Clinical partnered with Cambridge Cognition to transform patient recruitment for Central Nervous System (CNS) studies. The collaboration integrates Splash's recruitment capabilities with Cambridge Cognition's digital brain health services to help sponsors find participants for CNS-focused drug trials.

Scale indicators8 records

Recent moves8 records

Expansion highlights6 records

Broad incumbents

• Syneos Health: Syneos Health is a global CRO that provides clinical development and commercialization services, including patient recruitment solutions. Comparable to Splash Clinical as a competitor in the recruitment and site engagement space, though operating as a broad full-service provider.
• WCG (WIRB-Copernicus Group): WCG is a clinical services organization offering site solutions, IRB services, and patient engagement/recruitment technologies. Comparable to Splash Clinical given its involvement in clinical trial site support and patient engagement, though operating as a broader clinical services incumbent.
• ICON plc: ICON plc is a leading global CRO providing clinical research services including patient recruitment and decentralized trial solutions. Broadly comparable to Splash Clinical given its offering of digital recruitment and engagement services, though positioned as a full-service CRO rather than a recruitment specialist.
• IQVIA: IQVIA is the world's largest CRO and offers patient recruitment and site engagement as part of its full-service clinical trial portfolio. Comparable to Splash Clinical as it offers overlapping recruitment services, but as part of a much broader clinical and commercial services platform.

Direct peers

• Clariness: Clariness is a global patient recruitment company offering a patient portal (ClinLife) and recruitment services for clinical trials. Directly comparable to Splash Clinical given its similar focus on global digital recruitment and patient engagement across multiple therapeutic areas.
• Antidote: Antidote is a digital patient recruitment company for clinical trials, offering a search tool and engagement platform to match patients to trials. Directly comparable to Splash Clinical in providing technology-driven patient recruitment services to pharmaceutical sponsors and CROs.
• BBK Worldwide: BBK Worldwide is a patient recruitment and engagement company specializing in clinical trial enrollment and retention marketing. Highly comparable to Splash Clinical given its similar focus on global digital recruitment, engagement, and retention services for pharma and CRO clients.
• Acurian (PPD/Thermo Fisher Scientific): Acurian is a patient recruitment and retention company owned by PPD (now part of Thermo Fisher Scientific) that provides site identification, patient recruitment, and engagement services. Directly comparable to Splash Clinical as a specialist recruitment firm serving sponsors and CROs, though with the backing of a global CRO parent.
• SubjectWell: SubjectWell is a digital patient recruitment platform that connects clinical trial sponsors with patients through automated outreach. Comparable to Splash Clinical in providing tech-enabled patient recruitment services for clinical trials across multiple therapeutic areas.

Emerging players

• Medable: Medable is a decentralized clinical trial technology platform offering eCOA, eConsent, telehealth, and patient engagement tools. Comparable to Splash Clinical in the digital patient engagement layer of clinical trials, though Medable focuses on the broader DCT platform rather than specialist recruitment.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks1 record

Key highlights7 records

Customer concentration

Compliance5 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Splash Clinical