BioLegend

What BioLegend does

BioLegend, headquartered in San Diego, California, is a life science reagent manufacturer specializing in antibody-based products, recombinant proteins, immunoassays, and cell separation tools for biomedical research and clinical applications. Its core catalog spans flow cytometry reagents (including Brilliant Violet™ and StarBright™ dyes), MojoSort™ magnetic cell separation kits, LEGENDplex™ multiplex immunoassays, ELISA kits, recombinant cytokines and growth factors, and the TotalSeq™ family of oligonucleotide-conjugated antibodies that bridge protein detection with single-cell RNA/DNA sequencing on 10x Genomics, Illumina, and Mission Bio platforms. The company also operates a GMP-compliant Cell-Vive™ ancillary materials portfolio for cell and gene therapy bioprocessing and a clinical IVD/ASR product line under ISO 13485:2016 quality systems.

The business operates a hybrid go-to-market combining direct e-commerce (biolegend.com and regional storefronts), field sales representatives for bulk and custom work, and an authorized distributor network covering more than 90 countries, with wholly-owned regional entities in the UK, Netherlands, Japan, China, and Germany. Revenue is generated primarily through one-time catalog sales of catalog antibodies, proteins, and kits, supplemented by professional services (custom conjugation, custom immunoassay development) and managed services (GMP contract manufacturing). Pricing is unit-based for standard SKUs and quote-based for custom and bulk orders. BioLegend has been a wholly-owned subsidiary of Revvity — the S&P 500 health science company spun off from PerkinElmer in 2023 with $2.7B+ in 2023 revenue — since the 2021 acquisition, and serves pharmaceutical/biotech firms, academic institutions, government research programs, clinical laboratories, and biopharmaceutical manufacturers across more than 190 end markets.

Name

BioLegend

Legal name

BioLegend, Inc.

Website

https://biolegend.com

Company type

Private

Founded year

2002

Operating status

Operating

Headcount range

501–1,000 employees

Short description

BioLegend is a San Diego-based life science reagent company that develops and manufactures antibodies, recombinant proteins, immunoassays, and single-cell proteogenomics tools for academic, pharmaceutical, clinical diagnostics, and cell therapy manufacturing customers in 90+ countries.

Ownership category

akta.pro rank

Product category

Life Science Reagents

NAICS

Biological Product (except Diagnostic) Manufacturing (325414), In-Vitro Diagnostic Substance Manufacturing (325413)

SIC

Biological Products, (No Disgnostic Substances) (2836), In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

akta.pro secondary industries

Specialty & Biomarker Laboratory Services (Immunoassays/Flow/Cytometry) (HLAGAEAB), Cell Therapy Enabling Technologies (gene editing, cell engineering, delivery methods) (HLAAABAL)

Keywords

• Antibody reagents
• Flow cytometry reagents
• Immunoassay kits
• Recombinant proteins
• Cell separation kits

Headquarters

HQ city

San Diego

HQ country

United States

HQ region

North America

Offices6 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Supply Chain, Infrastructure

Revenue model

1. Research Antibodies and Reagents: Sale of catalog antibodies and reagents for research applications including flow cytometry, immunohistochemistry, immunofluorescence, Western blot, and other applications. Products are sold in various formats (purified, conjugated, lyophilized) with different fluorophore options.
2. Recombinant Proteins and Cytokines: Sale of bioactive recombinant proteins including cytokines, growth factors, chemokines, and enzymes for cell culture and research applications.
3. Immunoassays (ELISA and LEGENDplex™): Multiplex and singleplex immunoassay kits for detecting analytes in biological samples. Includes pre-defined panels and custom configurations.
4. Custom Reagents and Conjugation Services: Custom antibody conjugations, cocktail formulations (including fluorophore and TotalSeq™ options), custom recombinant proteins and antibodies, and custom ELISA/LEGENDplex configurations.
5. Custom Manufacturing Services: Contract manufacturing for research-grade and GMP-compliant materials including recombinant proteins, monoclonal/recombinant antibodies, cell culture media, and scalable production for bioprocessing applications.
6. Clinical Diagnostics (IVD and ASR): In Vitro Diagnostic products and Analyte Specific Reagents for clinical laboratory use in immunophenotyping and diagnostic applications.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels8 records

Core offering

BioLegend develops, manufactures, and distributes a catalog of thousands of antibody-based reagents for life science research, including flow cytometry antibodies, recombinant proteins (cytokines, growth factors, chemokines), multiplex immunoassays (LEGENDplex™), ELISA kits, and MojoSort™ magnetic cell separation products. The portfolio is anchored by proprietary platforms such as TotalSeq™ oligo-conjugated antibodies for single-cell proteogenomics, Flex-T™ MHC tetramers for antigen-specific T cell detection, and GMP-grade Cell-Vive™ ancillary materials for cell therapy bioprocessing, complemented by custom conjugation services and contract manufacturing for research and clinical applications.

Product overview

BioLegend is a life science reagent company offering a comprehensive portfolio of research tools organized around antibody-based products, immunoassays, and custom services. The core portfolio includes thousands of conjugated and unconjugated antibodies for flow cytometry, microscopy, Western blot, and immunohistochemistry applications, supplemented by recombinant proteins (cytokines, growth factors, chemokines), magnetic cell separation kits (MojoSort™), multiplex bead-based immunoassays (LEGENDplex™), and ELISA kits. TotalSeq™ oligo-conjugated antibodies enable proteogenomics workflows combining protein detection with single-cell RNA sequencing. The company provides GMP-grade Cell-Vive™ products for cell therapy bioprocessing and clinical IVD/ASR reagents for diagnostic laboratories. Custom solution capabilities include conjugation services, lyophilized antibody cocktails (XerosFlow™), custom immunoassay development, and contract manufacturing. Supporting web tools include spectral analyzers, panel builders, brightness indices, and a cloud-based Multiomics Analysis Software (MAS) for data analysis. BioLegend operates as part of Revvity and maintains ISO 13485:2016 compliant quality systems.

Differentiator

Problem solved

Functional benefit

Products and services

• Antibodies and Reagents Primary antibodies and reagents for flow cytometry, immunohistochemistry, immunofluorescence, Western blot, and other immunological applications, offered in purified and conjugated formats with various fluorophore options.
• MojoSort™ Magnetic Cell Separation Magnetic cell separation system using negative selection to isolate untouched cells for downstream flow cytometry, cell culture, and molecular biology applications.
• Recombinant Proteins, Cytokines, Growth Factors Bioactive recombinant proteins including cytokines, growth factors, chemokines, and enzymes validated in functional bioassays for cell culture and research applications.
• Ultra-LEAF™ and GoInVivo™ Antibodies Low endotoxin, azide-free purified bulk antibodies for in vivo research, cell culture, functional assays, and bioprocessing applications.
• TotalSeq™ Oligo-Conjugated Antibodies Oligonucleotide-conjugated antibodies available in TotalSeq-A, B, C, and D formats for simultaneous protein and RNA detection in single-cell RNA sequencing, high-parameter protein detection (PhenoCyte), and single-cell DNA analysis workflows.
• LEGENDplex™ Multiplex Immunoassays Bead-based multiplex assays that use flow cytometry to simultaneously quantify multiple soluble analytes in biological samples, available in pre-defined panels and custom configurations.
• ELISA Kits Enzyme-linked immunosorbent assay kits for detection and quantification of specific proteins in biological samples, including LEGEND MAX™ kits.
• FluoroSpot MAX™ Fluorescent spot assay for measuring multiple immune mediators such as IL-10, TNF-α, and IFN-γ in single wells to characterize complex immune responses.
• Flex-T™ MHC Tetramers and Monomers Soluble MHC molecules assembled into tetramers using UV-labile peptide exchange technology for identifying antigen-specific T cells in vaccine development and cancer research.
• Cell-Vive™ GMP Portfolio GMP-grade ancillary materials for cell therapy and ATMP bioprocessing, including antibodies and recombinant proteins compliant with USP<1043> and Ph. Eur. 5.2.12 for downstream manufacturing.
• StarBright™ Dyes Fluorescent dyes powered by Bio-Rad for conventional and spectral flow cytometry applications, licensed for RUO and clinical research use as antibody conjugates.
• Brilliant Violet™ Dyes Proprietary violet laser-excitable fluorescent dyes with minimized polymer dye interactions for multicolor flow cytometry panels.
• XerosFlow™ Lyophilized Cocktails Freeze-dried antibody cocktails with up to 24 months stability at room temperature (20-25°C), formulated with conventional fluorophores, Brilliant Violet™, and StarBright™ dyes to eliminate cold chain requirements.
• Clinical IVD and ASR Reagents In vitro diagnostic products and analyte-specific reagents for clinical laboratory use in immunophenotyping and diagnostic applications, including CE-marked products for the European market and ISO 13485:2016 compliant quality systems.
• Maxpar® Ready Antibodies Antibodies that can be metal-labeled for use in CyTOF® mass cytometry applications.
• Custom Conjugation and Cocktail Services Custom fluorophore and oligo conjugations, plus antibody cocktails in liquid, XerosFlow™ dry, and lyophilized formats, including Brilliant Violet™ and TotalSeq™ options tailored to specific experimental needs.
• Custom ELISA and LEGENDplex™ Immunoassays Custom multiplex immunoassays for quantifying multiple analytes in biological samples, with the ability to combine analytes across multiple kits.
• Contract Manufacturing Services GMP-compliant custom manufacturing for research-grade and bioprocessing-grade materials, including recombinant proteins, monoclonal and recombinant antibodies, cell culture media, and scalable production for cell therapy and bioprocessing applications.
• Flow Cytometry Panel Construction Service Expert panel design and optimization services provided by immunologists and flow cytometry specialists for building optimized multicolor flow cytometry panels.
• Multiomics Analysis Software (MAS) Free cloud-based software for analyzing single-cell RNA and protein data from TotalSeq™ multiomics experiments, designed for users without bioinformatics expertise.
• Fontus™ Cytometry Cocktail Prep Workstation Automated workstation for optimized antibody cocktail preparation and staining, enhancing precision, standardization, productivity, and traceability in clinical flow cytometry, linked with Revvity's clinical IVD product line.

Named customers4 records

Segments7 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature8 records

Partnerships

Nine partnerships are on record, tiered flagship and core.

• The Michael J. Fox Foundation for Parkinson's ResearchflagshipStrategic or Co-development Partner · 1 January 2026BioLegend is a participant and sponsor of the MJFF-led Parkinson's Progression Markers Initiative (PPMI), contributing data and samples for NIH AMP program. BioLegend's LEGEND MAX Human α-Synuclein ELISA kit has been used extensively in PPMI multi-centered studies. The partnership was built in collaboration with preeminent neuroscience leaders.
• NIH (National Institutes of Health)flagshipStrategic or Co-development Partner · 1 January 2026NIH and the Michael J. Fox Foundation partnership program for Parkinson's Disease research as part of the NIH Accelerating Medicines Partnership (AMP). BioLegend contributes as participant and sponsor for the PPMI initiative.
• RevvitycoreOthersBioLegend is now part of Revvity, a health science solutions company (spun off from PerkinElmer in 2023) with 2023 revenue of more than $2.7 billion and over 11,000 employees. Revvity provides complete workflows from discovery to development, and diagnosis to cure, with focus areas in translational multi-omics technologies, biomarker identification, imaging, and diagnostics.
• IlluminacoreTechnology or IntegrationCollaboration on BEN-seq workflow developed by BioLegend, where cells in suspension are stained with TotalSeq antibodies prior to bulk RNA sequencing using Illumina platforms. Enables combined protein and RNA analysis in bulk sequencing applications.
• Mission BiocoreTechnology or IntegrationPartnership for single-cell DNA and protein detection using TotalSeq-D reagents with Mission Bio's Tapestri platform. Enables resolution of complex genetic questions by combining single-cell DNA analysis with protein detection.
• Bio-Rad LaboratoriescoreTechnology or IntegrationPartnership for StarBright™ dyes (powered by Bio-Rad), fluorescent dyes for flow cytometry applications. StarBright conjugates are available for RUO and clinical research applications according to end user design specifications.
• Revvity (Intra-company)coreTechnology or IntegrationCross-selling and integrated product offerings within Revvity family. BioLegend IVD products link to Revvity's Fontus™ Cytometry Cocktail Prep Workstation for automated liquid handling. BioLegend TotalSeq reagents cross-promoted with Revvity single-cell sequencing products.
• 10x GenomicscoreTechnology or IntegrationTotalSeq reagents are compatible with 10x Genomics single-cell platforms for simultaneous protein and RNA detection in single-cell RNA sequencing workflows.
• Worldwide DistributorscoreChannel Partner/ Reseller/ DistributorExtensive network of authorized distributors covering over 90 countries. Major regional distributors include Cedarlane (Canada), Nordic Biosite (Nordic countries), Biomedica group (Central/Eastern Europe), and many specialized distributors in Asia-Pacific, Latin America, Middle East, and Africa.

Scale indicators4 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Bio-Rad Laboratories: Bio-Rad is BioLegend's most direct competitor in flow cytometry reagents and is also a technology partner (StarBright™ dyes are powered by Bio-Rad). Both companies sell antibody panels, dyes, and instrumentation consumables to immunology, cancer, and cell biology researchers globally.
• BD Biosciences: BD Biosciences is a leading provider of flow cytometry instruments and reagent kits, including fluorescent antibodies, multiplex bead arrays, and clinical IVD flow cytometry products. It directly competes with BioLegend in clinical and research flow cytometry and is a global incumbent in the installed-instrument base.
• Miltenyi Biotec: Miltenyi Biotec is a global competitor in magnetic cell separation (MACS®), flow cytometry reagents, and cell therapy manufacturing reagents — directly competing with BioLegend's MojoSort™ and cell-therapy-adjacent reagent portfolio. It has built an end-to-end cell therapy manufacturing offering that parallels Cell-Vive™.
• Cell Signaling Technology (CST): CST is a leading provider of highly validated antibodies and reagents, with a strong reputation in cell signaling, cancer, and neuroscience research — directly comparable to BioLegend's content library and validation-led positioning. CST competes on antibody specificity, reproducibility, and application support across Western blot, IHC, and flow cytometry.
• Bio-Techne (R&D Systems / Novus Biologicals / Tocris): Bio-Techne is a major competitor in recombinant proteins, cytokines/growth factors, ELISA kits, and research antibodies (via R&D Systems, Novus, and Tocris). It overlaps directly with BioLegend's recombinant protein and immunoassay businesses, including in GMP and cell therapy reagent adjacencies.
• Abcam: Abcam is one of the largest research antibody catalog businesses globally, offering polyclonal, monoclonal, and recombinant antibodies across essentially the same research applications as BioLegend (flow cytometry, IHC, Western blot, IF). It is a direct horizontal competitor in catalog antibody breadth and pricing.
• Cytek Biosciences: Cytek is a leading provider of spectral flow cytometry instruments and reagents; it directly competes with BioLegend in advanced flow cytometry workflows and benefits from instrument–reagent cross-selling similar in concept to BioLegend's Brilliant Violet™ and StarBright™ reagent strategies.

Broad incumbents

• Thermo Fisher Scientific (Invitrogen / eBioscience / Gibco): Thermo Fisher's life sciences brands (Invitrogen, eBioscience, Gibco, Thermo Scientific) offer an overlapping portfolio of research antibodies, recombinant proteins, cell culture reagents, and flow cytometry consumables. As a large incumbent, it competes with BioLegend across most catalog reagent categories and benefits from a much broader instrument and services footprint.

Emerging players

• 10x Genomics: 10x Genomics is BioLegend's single-cell sequencing platform partner (TotalSeq™ is compatible with 10x workflows) and an emerging adjacent player in single-cell multiomics reagents. It is a peer in the broader single-cell ecosystem where strategic choices by 10x can materially affect TotalSeq™'s positioning.
• Standard BioTools (formerly Fluidigm): Standard BioTools markets the CyTOF®/Hyperion® mass cytometry platform and Maxpar® metal-tagged antibody panel reagents — BioLegend sells Maxpar® Ready antibodies into the same workflow, making Standard BioTools a partially overlapping player in high-parameter cellular profiling.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/biolegend
• Facebookfacebook.com/biolegend
• LinkedInlinkedin.com/company/biolegend

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Subsidiaries4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about BioLegend