NuVasive

Name

NuVasive

Legal name

NUVASIVE®, INC.

Website

https://nuvasive.com

Company type

Private

Founded year

2001

Operating status

Acquired

Headcount range

1,001–5,000 employees

Ownership category

akta.pro rank

Product category

Spinal Surgery Medical Devices

NAICS

Surgical Appliance and Supplies Manufacturing (339113), Surgical and Medical Instrument Manufacturing (339112), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Surgical & Medical Instruments & Apparatus (3841), Electromedical & Electrotherapeutic Apparatus (3845)

akta.pro primary industry

Spine Implants & Motion Preservation (Fusion/Disc/Interspinous) (HLAHAEAC)

akta.pro secondary industries

Surgical Navigation, Robotics & Patient-Matched Instrumentation (Ortho/Spine) (HLAHAEAL), 3D-Printed & Patient-Specific Implants (Custom Ortho/Spine/Cranial) (HLAHAEAJ), Spine (Orthopedic Spine) (HLAKALAE)

Keywords

• Spinal surgery implants
• Minimally invasive spine surgery
• Robotic surgical navigation
• Intraoperative neuromonitoring services
• Medical device manufacturing

Headquarters

HQ city

San Diego

HQ country

United States

HQ region

North America

Offices19 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Supply Chain, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Spinal implants and surgical instruments: Sale of spinal implants including interbody spacers, fixation systems, and surgical instruments for various spinal procedures including XLIF, TLIF, ACDF, and deformity correction.
2. Enabling technologies: Robotic navigation systems, neuromonitoring services, and imaging technology that complement surgical procedures.
3. Biologics and regenerative products: Regenerative biologics including amniotic membrane, autologous PRP/BMAC, cellular allograft, DBM/allograft, and synthetic graft materials.
4. Intraoperative neuromonitoring services (NCS): Clinical services providing best-in-class IONM experience serving over 100,000 cases annually with board-certified neurologists and neurophysiologists.

Pricing tiers

Go-to-market motion1 record

Distribution channels2 records

Marketing channels5 records

Core offering

NuVasive designs, manufactures, and sells medical devices for spine surgery, including spinal implants (interbody spacers, fixation systems), minimally invasive surgical platforms (X360 lateral single-position surgery, XLIF), advanced biomaterials (Modulus, HEDRON, Cohere porous titanium/PEEK implants), robotic navigation systems (ExcelsiusGPS, ExcelsiusHub), intraoperative neuromonitoring (NVM5, NCS clinical services), and regenerative biologics. Products are sold directly to hospitals, ambulatory surgery centers, and spine surgeons globally across 40+ countries.

Product overview

NuVasive (now part of Globus Medical following 2023 merger) offers a comprehensive portfolio of spine surgery solutions organized around three core technology pillars: (1) X360 System - the comprehensive lateral single-position surgery platform integrating XLIF, XALIF, and XFixation procedures; (2) Advanced Materials Science - porous implant technologies including Modulus (titanium), HEDRON (3D-printed titanium), and Cohere (porous PEEK) designed for enhanced osseointegration; (3) Excelsius Technology ecosystem - robotic navigation and enabling technologies including ExcelsiusGPS, ExcelsiusHub, ExcelsiusXR, ExcelsiusFlex, and Excelsius3D. Supporting these are fixation systems (Reline, TLIF, Armada, VuePoint), interbody solutions (CoRoent, TLX, XCore), motion preservation (Simplify Cervical Disc), pediatric solutions (MAGEC, Reline Small Stature), neuromonitoring (NVM5, NCS Clinical Services), regenerative biologics, and power tools (DuraPro, Verzera). The portfolio is enhanced by integrated Global Alignment (iGA) platform for spinopelvic parameter assessment and the Pulse technology platform combining neuromonitoring, navigation, and imaging enhancement.

Differentiator

Problem solved

Functional benefit

Brands

• X360: Comprehensive lateral single-position surgery system integrating XLIF, XALIF, and XFixation procedures with Surgical Intelligence technologies
• Modulus
• Reline
• Pulse
• MAGEC
• Simplify
• NVM5
• Cohere
• HEDRON
• TLX

Products and services

• X360 System Comprehensive lateral single-position surgery platform integrating XLIF, XALIF, and XFixation procedures, designed to reduce OR time by up to 60 minutes and save nearly $5,000 per patient in hospital costs for spine surgeons and hospitals.
• Pulse Platform Integrated technology platform combining neuromonitoring, global alignment, navigation, rod bending, radiation reduction, and imaging enhancement in a single expandable system for spine surgeons.
• Advanced Materials Science Implants (Modulus, HEDRON, Cohere) Portfolio of porous titanium (Modulus, HEDRON) and porous PEEK (Cohere) interbody implant technologies designed to enhance osseointegration, biomechanical properties, and fusion outcomes for spine surgery patients.
• ExcelsiusGPS Robotic Navigation System Robotic navigation system for spine surgery providing autonomous targeting and trajectory planning with CT-based preoperative planning and real-time intraoperative navigation for spine surgeons and hospitals.
• ExcelsiusHub Navigation Platform Newest spine navigation platform with real-time patient array monitoring and tissue-sparing drills designed to elevate surgical safety and reproducibility for spine surgeons.
• ExcelsiusFlex Robotic Navigation System Robotic navigation and surgical guidance system designed for reconstructive orthopedic surgery applications beyond spine.
• ExcelsiusXR Augmented Reality Surgical Navigation AR headset providing augmented reality surgical navigation for enhanced visualization during spine procedures.
• Excelsius3D Intraoperative Imaging System 3D imaging system for intraoperative visualization and planning supporting robotic navigation workflows in spine surgery.
• Reline Posterior Fixation System Evolution of posterior fixation technology providing integrated Open and MAS procedural solutions for preserving or restoring spinal alignment; includes Reline MAS, Reline 3D, and Reline Small Stature variants for spine surgeons.
• TLIF Portfolio (including MAS TLIF 2) Transforaminal Lumbar Interbody Fusion portfolio providing open and MAS systems for TLIF procedures; MAS TLIF 2 is next-generation pedicle-based retractor with maximum visibility for spine surgeons.
• CoRoent Interbody Implants Family of PEEK interbody implants including multiple configurations (LI, LO, LC, LT, LW, Small Interlock for ACDF) using patented Insert and Rotate technique for various surgical approaches.
• Simplify Cervical Disc Motion-preserving cervical disc replacement device with PEEK on ceramic composition, anatomical sizing, variable rotation center, and MRI visibility for cervical disc replacement procedures.
• MAGEC Magnetic Growing Rods Magnetic growing rod system using an external remote controller (ERC) for non-invasive repeated distraction to treat early-onset scoliosis (EOS) without repeated surgeries in pediatric spine patients.
• XCore/XCore 2 Expandable Vertebral Body Replacement Expandable vertebral body replacement (VBR) system for modular corpectomy applications with multiple approach options; XCore 2 features XLIF-style endplates for higher subsidence resistance.
• TLX 20° Expandable Cage Expandable cage for posterior approach providing anterior column stability and sagittal alignment restoration with up to 20 degrees of customizable oblique lordosis.
• Armada Thoracolumbar Fixation System Thoracolumbar fixation system with sophisticated instrumentation and implants for treating pathologies ranging from degenerative to complex deformity in spine surgery.
• VuePoint Occipital-Cervical-Thoracic Fixation Occipital-cervical-thoracic fixation systems (VuePoint 1 and 2) for treating simple to complex deformity pathologies with low-profile multi-axial screws.
• Integrated Global Alignment (iGA) Platform Software platform providing spinopelvic parameter calculation, intraoperative real-time alignment assessment, and correlation with clinical outcomes for spine deformity correction.
• NVM5 Intraoperative Neuromonitoring System Intraoperative neuromonitoring system providing real-time monitoring of SSEP, EMG, MEP, BAER, DBS, and cortical mapping during spine and other surgeries for hospitals and surgeons.
• NCS Neuromonitoring Clinical Services Clinical services providing best-in-class intraoperative neurophysiological monitoring (IONM) with board-certified neurologists and neurophysiologists serving over 100,000 cases annually; certified by The Joint Commission.
• Power Portfolio (DuraPro, Verzera) Surgical power tools including the DuraPro oscillating system and Verzera navigated high speed drill designed to integrate with enabling technology for streamlined surgical workflows.
• Regenerative Biologics Portfolio Regenerative biologics portfolio including amniotic membrane, autologous PRP/BMAC/adipose, cellular allograft, DBM/allograft, graft delivery, and synthetic bone graft substitutes for spine surgery.

Quantifiable outcome

• Reduced OR time by up to 60 minutes per procedure
• +5 more outcomes

Named customers2 records

Segments4 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability9 records

Feature7 records

Partnerships

One partnership is on record.

• Globus MedicalcoreStrategic or Co-development Partner · 1 February 2023Globus Medical completed acquisition of NuVasive for $3.1 billion in February 2023, creating one of the largest entities in the spine and musculoskeletal space. The merger combined Globus Medical's Excelsius robotic platform with NuVasive's X360 lateral surgery portfolio and Advanced Materials Science technologies.

Scale indicators10 records

Recent moves9 records

Expansion highlights6 records

Direct peers

• Medtronic: Medtronic is NuVasive's largest direct competitor across spine implants, robotic navigation (Mazor), and intraoperative neuromonitoring (NVM5 competes with Medtronic's nerve monitoring portfolio that holds 18% global share versus NuVasive's 15%).
• Alphatec Holdings: Alphatec is a pure-play spine company offering lateral, posterior fixation, and biologics portfolios that directly overlap with NuVasive's X360, Reline, and regenerative biologics lines, with significant share of voice in the surgeon training and lateral approach segments.
• Orthofix Medical: Orthofix (which merged with SeaSpine) competes with NuVasive across spine implants, fixation, motion preservation, and orthobiologics, and overlaps in the pediatric/EOS segment where NuVasive's MAGEC rod competes with Orthofix's pediatric portfolio.

Broad incumbents

• Stryker: Stryker is a diversified medtech incumbent with a meaningful spine and neurosurgery franchise (including acquired Wright Medical assets) plus the Mako orthopedic robotics platform, positioning it as a broad competitor in robotic-enabled surgery that overlaps with ExcelsiusGPS.
• Johnson & Johnson (DePuy Synthes): Johnson & Johnson's DePuy Synthes spine division competes with NuVasive across interbody devices, fixation, and emerging enabling technologies; the broader J&J medtech R&D and capital resources make it a deep-pocketed incumbent competitor.
• Zimmer Biomet: Zimmer Biomet competes in spine via its spine and CMFT portfolio and offers the ROSA robotic platform for spine and brain surgery, overlapping with ExcelsiusGPS navigation and NuVasive's broader Enabling Tech push into orthopedics through ExcelsiusFlex.
• Boston Scientific: Boston Scientific overlaps with NuVasive through its neuromodulation and pain franchise (including spinal cord stimulation platforms) that competes with NuVasive's neuromonitoring and adjacent chronic pain opportunities, particularly after Nevro joined Globus Medical.

Emerging players

• Brainlab: Brainlab is a navigation and surgical software specialist whose spine imaging and computer-assisted surgery platform competes with NuVasive's ExcelsiusHub and Excelsius3D in the navigation-only segment of the enabling-tech stack.

Others

• Nevro Corp: Nevro (acquired by Globus Medical in 2025) provides the HFX spinal cord stimulation platform for chronic pain; not a NuVasive competitor per se but a now-sibling asset within the combined Globus-NuVasive platform expanding into neuromodulation.
• Carl Zeiss Meditec (ZEISS Medical Technology): ZEISS Medical Technology supplies intraoperative imaging and visualization hardware that integrates with multiple surgical robotics platforms (including competitive offerings with Globus/NuVasive Excelsius workflows) and serves as a complementary or substitute imaging source in spine ORs.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/user/globusmedical
• LinkedInlinkedin.com/company/nuvasive
• Instagraminstagram.com/globusmedicalinc
• Xx.com/nuvasiveinc
• Facebookfacebook.com/NuVasive

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles9 records

Subsidiaries14 records

Funding overview

Funding rounds3 records

Investors5 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A5 records

Investments1 record

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about NuVasive