Metrum Research Group
Metrum Research Group is a privately held professional services firm founded in 2004 that provides pharmacometric modeling and simulation consulting, cloud-based analytics (Metworx), and open-source tools to 200+ biopharmaceutical companies for model-informed drug development.
- Company typePrivate
- Founded2004
- HeadquartersTariffville, United States
- Headcount51–100
- GTM typeB2B
- OfferingServices
What Metrum Research Group does
Metrum Research Group is a privately held, Connecticut-based professional services firm founded in 2004 by Marc Gastonguay and Jeff Hane that delivers pharmacometric modeling and simulation (M&S) consulting to biopharmaceutical companies. The firm has served more than 200 life sciences clients, supporting model-informed drug development (MIDD) through population PK/PD modeling, exposure-response analyses, dose optimization, PBPK/QSP modeling, and clinical trial design analytics. Named enterprise clients include Boehringer Ingelheim, EMD Serono, and CSL Behring, with engagements spanning oncology, gene therapy, immunology, and rare diseases. Headcount is reported at 51–100 employees with offices in Tariffville, CT and Boston, MA.
MetrumRG operates a platform-plus-services model anchored by Metworx, a proprietary cloud-based computing environment that packages commonly used pharmacometric tools for distributed scientific work. The firm has built a substantial open-source ecosystem that includes mrgsolve (a differential-equation-based PK/PD simulator), MeRGE (an R package suite for reproducible pharmacometric workflows), bbr.bayes (Bayesian workflow tooling for NONMEM), and Stan/Torsten Bayesian analysis tools. Strategic Advisory Solutions, launched in November 2024, extends the firm's M&S expertise from project-based engagements to enterprise-tier drug development decision support.
The firm monetizes through three streams: project-based professional services engagements sold to biopharma program teams under custom pricing, Metworx platform subscriptions, and freemium open science content (courseware, open source tools) that supports demand generation and community building. Go-to-market is sales-led and driven by thought leadership — the firm publishes extensively, presents at major scientific conferences (ASCPT, ACoP, AACR, PAGE, ISOPOR), and operates an open courseware library engaging thousands of viewers globally. Michelle Johnson succeeded founder Marc Gastonguay as CEO in October 2022; Gastonguay continues as Chairman.
Metrum Research Group firmographics
Firmographics- Name
- Metrum Research Group
- Legal name
- Metrum Research Group
- Website
- https://metrumrg.com
- Company type
- Private
- Founded year
- 2004
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- Metrum Research Group is a privately held professional services firm founded in 2004 that provides pharmacometric modeling and simulation consulting, cloud-based analytics (Metworx), and open-source tools to 200+ biopharmaceutical companies for model-informed drug development.
- Ownership category
- akta.pro rank
Metrum Research Group industry classification
Industry- Product category
- Pharmacometric Modeling and Simulation Consulting
- NAICS
- Scientific Research and Development Services (5417), Other Scientific and Technical Consulting Services (54169), Research and Development in the Physical, Engineering, and Life Sciences (54171)
- SIC
- Services-Commercial Physical & Biological Research (8731), Services-Management Consulting Services (8742), Services-Prepackaged Software (7372)
- akta.pro primary industry
- Data Management, Biostatistics & Statistical Programming FSP (HLAGAOAB)
- akta.pro secondary industries
- Bioinformatics & Multi-omics Analysis Software (HLAGAJAD), AI/ML Platforms for Drug Discovery & Experiment Optimization (HLAGAJAO)
Keywords
Where Metrum Research Group is headquartered
LocationHeadquarters
- HQ city
- Tariffville
- HQ country
- United States
- HQ region
- North America
Offices3 records
Markets served
Metrum Research Group business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure
Revenue model
- Strategic Consulting Services: Strategic consulting and full project support providing data-driven decision making within clients' organizations, resourced with collaborative teams of top Modeling and Simulation scientists.
- Technology Solutions (Metworx): Cloud-based computing platform enabling quantitative scientists to perform analyses and share results supporting effective, data-driven decisions.
- Open Science Resources: Free courses and open-source tools offered to empower scientists, complementing paid professional services.
Go-to-market motion1 record
Distribution channels2 records
Marketing channels6 records
Metrum Research Group product offering
Product offeringCore offering
Metrum Research Group delivers strategic consulting and full project support in pharmacometric modeling and simulation to biopharmaceutical clients, with each engagement resourced by a collaborative team of Modeling and Simulation scientists. The company also operates Metworx, a cloud-based computing platform that lets quantitative scientists run commonly used tools in the cloud and share results, and publishes open-source packages (mrgsolve, MeRGE, bbr.bayes, Stan/Torsten) and free courseware to advance open science in drug development.
Product overview
Metrum Research Group offers a portfolio of quantitative science services and technology solutions for the life sciences industry. The core offering consists of Metworx, a cloud-based computing platform for quantitative scientists, complemented by Strategic Advisory Solutions for enterprise-level consulting and traditional Modeling and Simulation Services for project support. The company also provides an Open Science initiative featuring free open source tools (mrgsolve, MeRGE R packages, Stan/Torsten, Julia tools) and courseware to grow the pharmacometrics community. This platform-plus-services architecture enables data-driven decision making throughout the drug development lifecycle.
Differentiator
Problem solved
Functional benefit
Brands
- Metworx: Cloud-based computing platform that enables quantitative scientists to gain efficiencies by quickly and easily bringing the power of cloud computing to a platform of commonly used tools.
Products and services
- Metworx Metworx is a cloud-based computing platform that enables quantitative scientists to perform pharmacometric analyses and share results using commonly used tools, bringing the power of cloud computing to scientific workflows. It is targeted at biopharmaceutical quantitative scientists and pharmacometricians who need scalable, reproducible computational infrastructure.
- Strategic Advisory Solutions Strategic Advisory Solutions is an enterprise-level strategic consulting service that advances quantitative approaches to drug development decision-making, leveraging MetrumRG's over two decades of modeling and simulation expertise. It targets biopharma clients seeking strategic advisory services for drug development and was launched in November 2024.
- Modeling and Simulation Services Modeling and Simulation Services provide strategic consulting and full project support for data-driven decision making in drug development, delivered by a collaborative team of industry-leading Modeling and Simulation scientists. The offering is targeted at biopharmaceutical companies that need customized pharmacometric, PK/PD, exposure-response, PBPK, or QSP support across the drug development lifecycle.
- Open Science Tools and Courseware Open Science Tools and Courseware comprise free open-source software tools, open models, open courseware, and educational resources including mrgsolve, MeRGE R packages, Stan/Torsten Bayesian tools, and Julia-based pharmacometric modeling packages. They are offered to empower scientists and grow the pharmacometrics community.
Quantifiable outcome
- Delivered solutions to over 200 companies in the life sciences industry
- +1 more outcomes
Companies that use Metrum Research Group
Customer profileNamed customers4 records
Segments2 records
Ideal customer profiles1 record
Metrum Research Group technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability9 records
Feature5 records
Metrum Research Group partnerships and signals
Strategic signalPartnerships
Three partnerships are on record, tiered core.
- Boehringer IngelheimcoreLong-standing collaboration on multiple pharmacometric projects including population PK modeling of nerandomilast for IPF/PPF, exposure-response analyses, and various MIDD activities. Boehringer Ingelheim has collaborated with Metrum Research Group on numerous scientific publications and presentations at major conferences including ASCPT and ACoP.
- CSL BehringcoreCo-developed a novel agent-based computational model for liver-targeting AAV-based gene therapies predicting response durability in Hemophilia B patients treated with HEMGENIX (etranacogene dezaparvovec). The model simulates hepatocyte turnover and coagulation factor IX expression.
- EMD SeronocoreCollaboration on the JAVELIN Gastric 100 Phase III trial analysis, developing pharmacometric modeling and machine learning workflows to identify prognostic and predictive factors in oncology research. The resulting paper was one of the most cited publications in its journal.
Scale indicators3 records
Recent moves6 records
Expansion highlights6 records
Metrum Research Group competitors and assessment
Company assessmentMarket position
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
Metrum Research Group social profiles
Digital presenceMetrum Research Group financial estimates
Financial estimateRevenue estimate
Valuation estimate
Metrum Research Group leadership team
Management profileNumber of profiles
Profiles14 records
Metrum Research Group funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Metrum Research Group M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Metrum Research Group
What does Metrum Research Group do?
Metrum Research Group delivers strategic consulting and full project support in pharmacometric modeling and simulation to biopharmaceutical clients, with each engagement resourced by a collaborative team of Modeling and Simulation scientists. The company also operates Metworx, a cloud-based computing platform that lets quantitative scientists run commonly used tools in the cloud and share results, and publishes open-source packages (mrgsolve, MeRGE, bbr.bayes, Stan/Torsten) and free courseware to advance open science in drug development.
Is Metrum Research Group a public or private company?
Metrum Research Group is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Metrum Research Group founded?
Metrum Research Group was founded in 2004. It employs 51 to 100 people.
Where is Metrum Research Group based?
Metrum Research Group is headquartered in Tariffville, United States, in the North America region.
How does Metrum Research Group make money?
Three revenue lines are on record. Strategic Consulting Services are the primary driver. The others are technology Solutions (Metworx) and open Science Resources.
Does Metrum Research Group have an API?
No public API is recorded for Metrum Research Group.
What industry is Metrum Research Group in?
Metrum Research Group's product category is Pharmacometric Modeling and Simulation Consulting. Its primary akta.pro industry code is HLAGAOAB, Data Management, Biostatistics & Statistical Programming FSP, with a secondary code of HLAGAJAD, Bioinformatics & Multi-omics Analysis Software. Its NAICS code is 5417 and its SIC code is 8731.