Xilloc

What Xilloc does

Xilloc, legally Xilloc Medical Int, is a Netherlands-based medical device company founded in August 2011 by Maikel Beerens that specialises in patient-specific 3D-printed and CNC-machined implants and surgical aids for craniomaxillofacial (CMF) surgery. Its portfolio spans six core implant product lines — cranial reconstruction in PEEK and titanium (the latter with integrated Interfix fixation), temporomandibular joint (TMJ) reconstruction developed with UMC Groningen, mandibular reconstruction plates, facial augmentation, and orbital floor implants — complemented by surgical aids including patient-specific anatomical models, surgical guides, and the One Stage workflow that combines resection and reconstruction in a single operation. Production is fully in-house at the Brightlands Campus facility in Sittard-Geleen under EU MDR 2017/745 Class III and ISO 13485:2016 certifications, with case management, CT upload, design collaboration, and approval handled through the proprietary Xilloc Portal.

The company monetises on a project-based, quote-priced model: each implant and surgical aid is custom-designed from CT data per case, with PEEK implants delivered within three working days and titanium within five, and urgent cases fulfilled within 36 hours or next-day. The primary customer segments are CMF surgeons (neurosurgeons, craniofacial and oral/maxillofacial specialists) at European university hospitals and in-house hospital 3D labs that outsource certified manufacturing; a secondary B2B channel provides contract manufacturing under Xilloc's ISO 13485 and MDR certifications for third-party medical-device companies that need a legal manufacturer. Distribution runs direct within the EU under MDR and through international agents and distributors elsewhere, with Ovidius Solutions serving the UK market since 2019.

The company is privately held; Holland Capital invested alongside new CEO Milko Wijckmans in 2021 to professionalise operations, the EU MDR Class III milestone was reached in 2025, and a rebranding plus a new Xilloc Portal were announced for 2026. Headcount is in the 11–50 range, and the company has not disclosed revenue or follow-on funding beyond the 2021 round and a small 2015 EISMEA grant.

Name

Xilloc

Legal name

Xilloc Medical Int

Website

https://xilloc.com

Company type

Private

Founded year

2011

Operating status

Operating

Headcount range

11–50 employees

Short description

Xilloc designs and manufactures patient-specific 3D-printed craniomaxillofacial (CMF) implants and surgical aids in PEEK and titanium, selling on a per-case, quote-based model to CMF surgeons and hospital 3D labs across Europe from its EU MDR Class III-certified facility in Sittard-Geleen, Netherlands.

Ownership category

akta.pro rank

Product category

Patient-Specific Craniomaxillofacial (CMF) Implants

NAICS

Surgical and Medical Instrument Manufacturing (339112), Surgical Appliance and Supplies Manufacturing (339113), Medical Equipment and Supplies Manufacturing (3391)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Neurosurgical Implants & Cranial/CMF (Cranial Plates, Dural Repair, Shunts) (HLAHAEAD)

akta.pro secondary industries

3D-Printed & Patient-Specific Implants (Custom Ortho/Spine/Cranial) (HLAHAEAJ), Medical & Dental 3D Printing Services (patient-specific devices, dental labs) (IMAAADAG), Medical & Dental Prototyping (Models, Guides, Pre-Op Planning) (IMAAAFAI), Medical Devices & Dental (Production AM Parts) (IMAAAEAD)

Keywords

• Patient-specific implants
• Craniomaxillofacial medical devices
• 3D-printed surgical implants
• Additive manufacturing medical
• Custom surgical guides

Headquarters

HQ city

Maastricht

HQ country

Netherlands

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Technology or R&D, Supply Chain, Marketing or Sales

Revenue model

1. Patient-Specific CMF Implants: Design, manufacture, and sale of patient-specific cranial, facial, mandibular, orbital, and TMJ implants in PEEK and titanium materials. Revenue is project-based per case, with turnaround typically within 3-5 working days after design approval.
2. Surgical Aids: Production and sale of patient-specific surgical guides, anatomical models, and One Stage surgical solutions that support implant placement and surgical procedures.
3. Contract Manufacturing: Xilloc acts as a legal manufacturer producing patient-specific implants (PEEK, titanium), surgical guides, and anatomical models for third-party designers under ISO 13485 and MDR-certified conditions. Accepts design files (STL, STEP, OBJ, Parasolid) via Xilloc Portal.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

Xilloc designs, manufactures, and delivers patient-specific 3D-printed craniomaxillofacial (CMF) implants in PEEK and titanium from CT scan data, complemented by patient-specific surgical guides, anatomical models, and One Stage combined resection-reconstruction solutions. It also provides ISO 13485 / EU MDR-certified contract manufacturing as a legal manufacturer for third-party medical device companies, with every case routed through its proprietary Xilloc Portal.

Product overview

Xilloc offers a unified portfolio of patient-specific craniomaxillofacial (CMF) implants and surgical aids. The core offering consists of six implant product lines spanning cranial reconstruction in PEEK and titanium, temporomandibular joint (TMJ) reconstruction, mandibular reconstruction, facial augmentation, and orbital floor repair. These are complemented by three surgical aid categories: anatomical models, One Stage combined resection-reconstruction procedures, and surgical guides. A contract manufacturing service extends manufacturing capabilities to third parties. All offerings are managed through the Xilloc Portal customer platform. The company operates from Sittard-Geleen, Netherlands, with EU MDR Class III and ISO 13485 certification.

Differentiator

Problem solved

Functional benefit

Products and services

• Cranial Reconstruction (PEEK)

Quantifiable outcome

• Design turnaround of 2-3 working days (1 day for urgent cases)
• +4 more outcomes

Named customers7 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature9 records

Partnerships

Six partnerships are on record, tiered core.

• TÜV SÜD (EU Notified Body)coreOthers · 1 January 2025TÜV SÜD serves as Xilloc's EU Notified Body, issuing the EU MDR 2017/745 Class III and ISO 13485:2016 certifications that enable legal distribution of patient-specific medical devices within the EU and position Xilloc as a certified legal manufacturer.
• Ovidius SolutionscoreChannel Partner/ Reseller/ Distributor · 1 January 2019First international distributor appointed in the United Kingdom in 2019. Ovidius Solutions represents Xilloc's patient-specific CMF implants and surgical aids in the UK market, enabling broader international access to Xilloc's solutions.
• Radboud UMC 3D LabcoreStrategic or Co-development PartnerLong-term strategic partnership where Radboud UMC's 3D Lab is responsible for product design, material selection, and product specifications, while Xilloc handles production, quality control, sterile delivery, and the manufacturing process. The partnership enables rapid switching and real-time alignment of patient-specific requirements during design, with Xilloc delivering products on time and to specification.
• Dr. Paul Pakos (Universitätsklinik Würzburg)coreStrategic or Co-development PartnerClinical collaboration on patient-specific implant cases including PEEK inlay for cranial deformity and titanium inlay cranioplasty after ischemic stroke. Dr. Pakos provides surgical input for design and validates the clinical outcomes, contributing published case evidence.
• Maastricht UMC+ (Department of Cranio-Maxillofacial Surgery)coreStrategic or Co-development PartnerLong-standing collaboration for patient-specific implant design and placement, including complex reconstruction cases. Maastricht UMC+ surgeons collaborate with Xilloc engineers on design approval and provide clinical validation of outcomes.
• Universitair Medisch Centrum Groningen (UMCG)coreStrategic or Co-development PartnerJoint development of patient-specific TMJ (temporomandibular joint) implants. UMCG contributed to the implant design and development, and continues to collaborate on clinical application of the multi-component TMJ reconstruction solution.

Scale indicators4 records

Recent moves9 records

Expansion highlights6 records

Direct peers

• Materialise: Materialise is a leading 3D printing service bureau and software provider with a dedicated medical division offering patient-specific implants and surgical guides for CMF, orthopedic, and dental use cases — directly comparable in capability, regulatory posture, and target customers to Xilloc.
• Medartis: Medartis specializes in implants and instruments for CMF, hand, and upper extremity surgery, including patient-specific solutions, making it a directly comparable specialist peer in the same surgical disciplines.
• Oxford Performance Materials: Oxford Performance Materials manufactures 3D-printed PEEK patient-specific cranial and facial implants (OsteoFab), overlapping directly with Xilloc's PEEK cranial and facial implant portfolio.
• Anatomics: Anatomics is a patient-specific implant and surgical planning company specializing in CMF and cranial reconstruction using 3D-printed PEEK and titanium — directly comparable in clinical niche and product approach to Xilloc.
• KLS Martin Group: KLS Martin is a long-established manufacturer of CMF surgery implants and instruments, including patient-specific solutions (e.g., IPS Implants). Overlaps directly with Xilloc in craniomaxillofacial reconstruction and trauma implants.

Broad incumbents

• DePuy Synthes (Johnson & Johnson MedTech): DePuy Synthes offers a broad CMF and cranial portfolio (including patient-specific implants via its Synthes ProPlan workflow) and is the dominant incumbent in CMF surgery — a relevant comparator for Xilloc's flagship cranial and mandibular reconstruction lines.
• Stryker: Stryker's Craniomaxillofacial and 3D printing business (including CMF, neuro, and patient-specific solutions) directly overlaps with Xilloc's patient-specific implants, with substantially larger commercial reach into hospitals.
• 3D Systems (Healthcare): 3D Systems Healthcare provides patient-specific surgical planning, anatomical models, and 3D-printed medical devices including CMF implants through its Regenerative Medicine and Healthcare businesses.

Emerging players

• TRUMPF: TRUMPF's medical technology division produces patient-specific titanium cranial and spinal implants using additive manufacturing, making it a relevant comparably sized European competitor in patient-specific CMF.
• Renishaw: Renishaw's Healthcare division offers 3D-printed patient-specific implants (e.g., cranial and maxillofacial), with overlapping capabilities in metal 3D printing and regulatory-certified medical device manufacturing.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/xilloc
• Facebookfacebook.com/Xilloc
• LinkedInlinkedin.com/company/xilloc-medical

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Xilloc