What CRScube does

CRScube Inc. is a Seoul-headquartered SaaS provider of eClinical software for clinical trials, founded in 2011 and serving pharmaceutical, biotechnology, medical device, and contract research organization (CRO) customers globally. Its core product is cubeCDMS, an electronic data capture (EDC) platform, extended by a unified suite covering pharmacovigilance (cubeSAFETY), randomization and trial supply management (cubeIWRS), direct data capture (cubeDDC), electronic patient-reported outcomes (cubePRO) with the cubeBUILDER configuration tool, electronic consent (cubeCONSENT), clinical trial management (cubeCTMS), trial master file (cubeTMF), risk-based quality management (cubeRBQM), and a learning management system (cubeLMS). The platform is cloud-based on AWS infrastructure with primary data centers in Tokyo and Seoul and disaster recovery in AWS Oregon, accessed via web browser without installation. CRScube holds broad regulatory and quality certifications including FDA 21 CFR Part 11, EMA computerized systems compliance, ISPE GAMP 5, CDISC ODM Platinum membership, WHODrug B3/C3, ISO/IEC 27001:2022, and ISO 9001:2015, and reported FDA inspections of cubeSAFETY and cubeCDMS in 2024 with zero system-related findings. The company is developing an AI-led EDC builder that processes PDF protocols via NLP to automatically generate study databases and compress traditional 8-12 week study build cycles.

The business operates a direct enterprise SaaS sales model with regional offices in Seoul, Minnetonka (US, established via the November 2025 acquisition of Mednet Solutions Inc.), Shanghai, Tokyo, and London. Revenue is generated through annual subscriptions to the unified eClinical platform, complemented by professional services for implementation, training (including the Train-the-Builder program), biometrics, and customer support. Customers include global pharmaceutical firms, mid-size biotech, large CROs (e.g., Linical, EPS), and the top five Korean pharmaceutical companies, with documented outcomes including 50-60% direct cost reductions versus legacy EDC vendors, 80% safety reporting budget reductions for biotech adopters, and 99.99%+ platform uptime. The company is bootstrapped with no venture capital or institutional investment, reported $7.6M in ARR and a $22.8M valuation as of 2025, and aggregates a track record of approximately 8,400 studies, 182,000 site users, 2.6 million patients, and 350+ regulatory approvals since 2010.

The Mednet acquisition in November 2025 is the most consequential recent move, combining CRScube's established Asia-Pacific position (6,000+ pre-acquisition trials) with Mednet's North American footprint (100+ FDA approvals supported) and transforming the go-to-market into a true global eClinical platform. Distribution combines direct enterprise field sales, a formal partner channel program with train-the-builder enablement, and self-service web access for mid-market adoption. Pricing is quote-based and not publicly disclosed. CRScube positions itself as an affordable, cost-effective alternative to legacy eClinical vendors, with a value proposition grounded in single sign-on platform integration, multi-regulatory compliance, and AI-assisted study build automation.

Name

CRScube

Legal name

CRScube Inc.

Website

https://crscube.io

Company type

Private

Founded year

2011

Operating status

Operating

Headcount range

101–250 employees

Short description

CRScube is a bootstrapped Seoul-headquartered SaaS provider of unified eClinical solutions, including EDC, pharmacovigilance, RTSM, ePRO, CTMS, eTMF, and RBQM, serving pharmaceutical, biotechnology, medical device, and CRO customers globally, with AI-led EDC build automation in development.

Ownership category

akta.pro rank

Product category

eClinical Software Platform

NAICS

Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (5182), Custom Computer Programming Services (541511)

SIC

Services-Prepackaged Software (7372), Services-Computer Programming, Data Processing, Etc. (7370)

akta.pro primary industry

Clinical Data Management, Biostatistics & Statistical Programming CROs (HLAGAAAF)

Keywords

• Electronic data capture
• Clinical trial management
• Eclinical platform
• Pharmacovigilance software
• Randomization and trial supply

Headquarters

HQ city

Mapo

HQ country

South Korea

HQ region

Asia

Offices5 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel

Revenue model

1. SaaS Subscription - eClinical Platform: CRScube generates revenue through annual SaaS subscriptions for its unified eClinical platform covering EDC, pharmacovigilance, RTSM, CTMS, eTMF, and patient-facing solutions. The subscription model includes software access, support, and maintenance with pricing based on study complexity and scope.
2. Professional Services - Implementation & Training: Revenue generated from implementation services, training programs (Train-the-builder program), and customer support services including study build instruction and biometrics services.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels7 records

Core offering

CRScube provides a unified, cloud-based eClinical SaaS platform for managing clinical trials. Its core offering centers on cubeCDMS for Electronic Data Capture, complemented by pharmacovigilance (cubeSAFETY), RTSM (cubeIWRS), direct data capture (cubeDDC), ePRO (cubePRO), eConsent (cubeCONSENT), CTMS, eTMF, RBQM, LMS, and AI-led automation tools. The company also offers professional services including biometrics, eClinical setup, medical writing, and customer support.

Product overview

CRScube offers a unified eClinical platform combining multiple interconnected solutions: cubeCDMS as the core Electronic Data Capture (EDC) system, supplemented by site-focused solutions (cubeIWRS for randomization and supply management, cubeDDC for direct data capture), patient-facing tools (cubePRO for ePRO, cubeCONSENT for eConsent), trial team management (cubeCTMS, cubeTMF, cubeRBQM, cubeLMS), pharmacovigilance (cubeSAFETY), and AI-powered automation capabilities. All solutions are accessible via web browser without installation, operate on a SaaS model, and can be used independently or as a unified platform.

Differentiator

Problem solved

Functional benefit

Products and services

• cubeCDMS CRScube's flagship Electronic Data Capture (EDC) platform that enables convenient and efficient management of clinical data with accurate eCRF data collection. Serves as the cornerstone of the unified eClinical platform for clinical trial sponsors and CROs.
• cubeSAFETY Pharmacovigilance solution that simplifies adverse event reporting and reduces workload. Complies with FDA, EMA, PMDA, NMPA, and MFDS regulations, automates case processing, and integrates with EDC systems.
• cubeIWRS Interactive Web Response System (RTSM) offering integrated functionalities for investigational products from randomization to IP return. Seamlessly integrates with cubeCDMS for accurate and streamlined IP-related tasks on a single platform.
• cubeDDC Direct Data Capture solution that collects high-quality clinical data without the need for paper source documents, eliminating double data entry and ensuring data reliability.
• cubePRO Electronic Patient Reported Outcomes (ePRO) solution for patient-centric data collection. Questionnaires are easily set up using cubeBUILDER with edit checks ensuring clean data, and ePRO data automatically synchronizes to cubeCDMS.
• cubeCONSENT Electronic informed consent solution that streamlines the informed consent process for clinical trial participants. Participants consent via eSignatures which investigators review for final signature.
• cubeCTMS Clinical Trial Management System providing comprehensive view and management of overall trial progress and operational milestones, enabling central monitoring.
• cubeTMF Trial Master File solution providing a validated paperless clinical trial environment compliant with FDA CFR 21 Part 11. Automated workflows reduce time and cost of managing documents.
• cubeRBQM

Quantifiable outcome

• EDC setup timelines compressed from 8-12 weeks to a fraction of that time using AI-led EDC builder
• +5 more outcomes

Named customers10 records

Segments5 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability6 records

Feature6 records

Partnerships

One partnership is on record.

• Mednet Solutions Inc.coreStrategic or Co-development Partner · 18 November 2025CRScube completed the acquisition of Mednet, a US-based eClinical technology company specializing in electronic data capture. The transaction combines CRScube's strong Asian market position (6,000+ trials worldwide) with Mednet's established North American presence (100+ FDA approvals), creating a unified global eClinical platform. Both companies will continue serving existing clients while aligning operations.

Scale indicators11 records

Recent moves7 records

Expansion highlights6 records

Direct peers

• Veeva Systems: Veeva offers Vault CTMS, Vault EDC and the broader Vault Clinical Operations suite that directly competes with CRScube's unified eClinical platform. Both target pharma and CRO customers with SaaS clinical trial technology, making Veeva the most direct large-scale comparable.
• Medidata Solutions (Dassault Systèmes): Medidata's Rave EDC, Rave RTSM, Rave CTMS and Rave eTMF overlap directly with cubeCDMS, cubeIWRS, cubeCTMS and cubeTMF. Medidata is the legacy enterprise leader in EDC and a primary competitor for large pharma CRO contracts.
• Castor: Castor offers a cloud EDC platform with ePRO, eConsent and CTMS extensions targeting academic, biotech and CRO customers. Direct overlap with CRScube's mid-market positioning and similar self-service plus enterprise hybrid GTM motion.
• Medrio: Medrio provides an EDC-centric SaaS platform with ePRO, eConsent and RTSM, targeting pharma, biotech and CRO customers. Highly comparable in product scope and mid-market orientation, and a direct competitor for cubeCDMS sales.
• Signant Health: Signant Health offers an eClinical suite covering EDC, ePRO, RTSM, eCOA and patient engagement that mirrors CRScube's modular offering. Serves overlapping pharma and biotech customer segments with similar unified-platform value propositions.
• Clario: Clario delivers eClinical technology and clinical endpoint solutions including EDC, RTSM and eCOA. Direct overlap with CRScube's product set and a meaningful competitor for pharma and biotech trial technology contracts.
• ArisGlobal: ArisGlobal's LifeSphere platform spans clinical, regulatory, safety (pharmacovigilance) and medical affairs. Overlaps directly with CRScube's cubeSAFETY and CTMS modules and competes for the same mid-to-large life sciences customers.

Broad incumbents

• Oracle Health Sciences (Clinical One): Oracle's Clinical One platform competes with CRScube's unified eClinical suite across EDC, RTSM and CTMS. As a broader enterprise software incumbent with massive R&D and global infrastructure, Oracle competes at the top end of the market where CRScube seeks to expand.
• IQVIA (Technology & eClinical): IQVIA combines CRO services with an eClinical technology portfolio that competes with CRScube's platform across EDC, RTSM and CTMS. As the largest CRO with proprietary technology, IQVIA is a broad incumbent that bundles services and software.

Emerging players

• Formedix (Instem): Formedix (now part of Instem) provides clinical trial design, CDISC standards automation and EDC build tools that overlap with CRScube's AI-led EDC builder and CDISC ODM-aligned offerings. Smaller-scale, niche player with partial overlap.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/crscube

Compliance7 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Subsidiaries3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about CRScube