What InFocus Clinical Research does

InFocus Clinical Research is a Brentwood, Tennessee-based full-service contract research organization (CRO) specializing exclusively in clinical trials for retinal and ophthalmic therapeutics. Founded in 2001 by Brad Doerschuk (originally as PharmaMed Research) in partnership with what the company describes as the largest consortium of retina specialists globally, InFocus serves pharmaceutical and emerging biotechnology companies developing drugs for indications including age-related macular degeneration, diabetic retinopathy, geographic atrophy, retinitis pigmentosa, Stargardt disease, and other inherited retinal diseases. The company supports Phase 1 through Phase 4 studies plus investigator-initiated trials, with services spanning project management, clinical monitoring, medical monitoring, data management and biostatistics, pharmacovigilance/safety management, regulatory affairs, global project leadership, and advisory board and investigator meeting planning. Customer testimonials indicate a particular emphasis on emerging and small biotech sponsors requiring flexible engagement for smaller or novel programs.

The company's underlying technology stack is purpose-built for the retina CRO niche. Its proprietary platforms include the eVision CTMS/eTMF system (a clinical trial management system with integrated electronic trial master file and monitor-visit calendar designed specifically for ophthalmology), the Real-Time Intelligence (RTI) database covering more than 550 global retina research sites with live enrollment, contract, and performance data, white-labeled study portals for sponsor-branded document and communication hosting, the InFocus Cash Cards participant reimbursement system, and a Feasibility Assessment Engine integrated with the RTI database. Data management operates on certified EDC platforms including Medidata Rave, IBM CD (Merative), and Medrio, with SAS programming capability in-house. Sister-company AIBILI (Portugal) extends the stack with a full-service reading center (CORC) for imaging assessments and European site targeting.

Commercially, InFocus operates a project-based professional services model priced via custom Request-for-Proposal quotes that vary by trial phase, indication, geography, and complexity, typically structured as multi-year contracts. Customer acquisition runs through direct enterprise sales supported by thought leadership (blog, educational resources on retinal diseases), active participation in major ophthalmology conferences (AAO, ASRS, Euretina, Retina Society, Macula Society, APVRS, OIS, Hawaiian Eye and Retina, FloRetina), and referral leverage through its Scientific Advisory Board of leading retina KOLs. The company is privately held by its founder and operating partner KOLs, with no disclosed venture capital or institutional funding rounds.

Name

InFocus Clinical Research

Legal name

InFocus Clinical Research LLC

Website

https://infocusclinical.com

Company type

Private

Founded year

2001

Operating status

Operating

Headcount range

101–250 employees

Short description

InFocus Clinical Research is a Brentwood, TN-based full-service contract research organization specializing exclusively in retina and ophthalmology clinical trials for pharmaceutical and biotechnology sponsors, supported by proprietary technology including the eVision CTMS platform and a 550-site Real-Time Intelligence database.

Ownership category

akta.pro rank

Product category

Contract Research Organization (CRO) Services for Ophthalmic Clinical Trials

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Health Services (8000)

akta.pro primary industry

Specialty Therapeutic-Area CROs (e.g., oncology/rare disease) (HLAGAAAL)

akta.pro secondary industries

Clinical CROs (Phase I–IV) (HLAGAAAA), Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM), Clinical Data Management, Biostatistics & Statistical Programming CROs (HLAGAAAF), Pharmacovigilance, Risk Management & Medical Affairs CROs (HLAGAAAH)

Keywords

• Retina clinical trials
• Ophthalmology CRO services
• Contract research organization
• Clinical trial management
• Clinical monitoring services

Headquarters

HQ city

Brentwood

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales

Revenue model

1. Clinical Research Services: Full-service CRO providing comprehensive clinical trial services for retina and ophthalmology drug development including project management, clinical monitoring, medical monitoring, data management, biostatistics, regulatory affairs, safety management, and advisory board services. Revenue generated through professional services contracts with pharmaceutical and biotech companies conducting clinical trials.

Pricing tiers

Go-to-market motion2 records

Distribution channels1 record

Marketing channels6 records

Core offering

InFocus Clinical Research is a full-service retina specialty Contract Research Organization (CRO) that delivers end-to-end clinical trial services for pharmaceutical and biotechnology companies developing ophthalmology and retinal therapeutics. Core services span project management, clinical monitoring, medical monitoring, data management and biostatistics, regulatory affairs, pharmacovigilance/safety management, and advisory board and meeting planning, executed across Phase 1 through Phase 4 and Investigator-Initiated Studies. The company differentiates itself through therapeutically-aligned ophthalmology-dedicated staff, a Scientific Advisory Board of leading retina key opinion leaders, and proprietary technology including the eVision CTMS platform and a Real-Time Intelligence database covering 550+ global retina research sites.

Product overview

InFocus Clinical Research is a full-service retina specialty Contract Research Organization (CRO) offering an integrated portfolio of services and proprietary technology platforms for ophthalmology clinical trials. The core offering consists of clinical research services including Project Management, Clinical Monitoring, Medical Monitoring, Data Management & Biostatistics, Safety Management, Global Project Leadership, and Advisory Board & Meeting Planning. These services are supported by proprietary technology platforms: eVision CTMS (clinical trial management with eTMF), the Real-Time Intelligence (RTI) Database (site network intelligence), Study Portals (document management), InFocus Cash Cards (participant payments), and Email Communications tools. The company operates across all clinical trial phases (Phase 1 through Phase 4 and IIS) with therapeutically-aligned staff and access to over 550 global retina research sites.

Differentiator

Problem solved

Functional benefit

Brands

• eVision CTMS: Proprietary CTMS/eTMF platform designed specifically for the ophthalmology space, includes eTMF for archiving study documents and monitor-visit calendar.
• Real-Time Intelligence (RTI)
• InFocus Cash Cards

Products and services

• Project Management Comprehensive project management services for clinical trials ranging from small single-center Phase 1 PK/PD protocols to large 200-site, 2000-patient Phase IIIb and IV protocols. Project managers have experience working for sponsor companies.
• Clinical Monitoring Premier-level clinical monitoring services provided by ophthalmology-dedicated clinical research professionals with an average of over 15 years of experience and a project retention rate over 90% from initiation to closure.
• Medical Monitoring Medical monitoring services with access to a Scientific Advisory Board of proven retina leaders, including protocol development, scientific analysis, data safety monitoring, and full-service medical monitoring.
• Support Services Clinical research support including budgets and contracts, grants and investigator payments management, regulatory affairs including eTMF, and CRF development.
• Data Management and Biostatistics Data management and biostatistics services led by Ken Milstead with over 25 years of experience. The company is certified in Medidata Rave, IBM CD (Merative), and Medrio EDC platforms.
• PV and Safety Management Pharmacovigilance and safety management services including oversight and development of Safety SOPs, Safety Manuals, SAE narratives, and reporting to Safety Review Committees.
• Global Project Leadership Experienced project management team with expertise leading trials throughout the world.
• Advisory Board and Meeting Planning Full-service advisory board development and management including KOL network development, organizing and running advisory board meetings, investigator meetings, and other relevant events with associated meeting materials (agenda, briefing document, PowerPoint presentation, meeting minutes).
• Phase 1 Clinical Trial Services Specialized clinical study expertise for Phase 1 trials including first time in human, dose tolerance, food effect, Pharmacokinetic (PK), and Pharmacodynamic (PD) studies with dedicated monitoring services.
• Phase 2 and 3 Clinical Trial Services Clinical trial services for Phase II and III studies with expertise in length, complexity in design, and diverse indications with site/investigator selection, training, and protocol adherence.
• Phase 4 and IIS Clinical Trial Services Phase IV studies and Investigator Initiated Studies with capabilities including enrollment acceleration, regulatory navigation, digital marketing, and engagement support.
• eVision CTMS / eTMF Platform Proprietary Clinical Trial Management System (CTMS) with robust eTMF for archiving study documents and an industry-leading monitor-visit calendar. Designed specifically for ophthalmology and integrates with study EDC for enrollment and site reporting.
• Real-Time Intelligence (RTI) Database Proprietary database tracking over 550 global retina research sites with data on enrollment, contract negotiation, start-up timelines, personnel, site-specific and performance-related metrics. Integrated with a digital Feasibility Assessment Engine.
• Study Portals Web-based, password-protected study portals for all relevant study documents, training materials, and communications. White-labeled for sponsors and hosted on branded URLs with design, development, launch, and maintenance managed by InFocus.
• InFocus Cash Cards Participant reimbursement and payment solution that simplifies the payment process, eliminates administrative burden on site staff, and provides prompt fair payments to participants without complicated forms.
• RTI Site Network Proprietary database of more than 550 global retina research sites (private and academic) tracking enrollment, contract negotiation, start-up timelines, operational issues, personnel, and assessment capabilities, used for site selection and enrollment optimization.

Quantifiable outcome

• Ranked #434 on 2025 Inc. 5000 list (up from #724)
• +2 more outcomes

Named customers4 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Seven partnerships are on record, tiered core and minor.

• AIBILI (Association for Innovation and Biomedical Research Into Light and Image)coreStrategic or Co-development PartnerSister company based in Portugal that enables easy targeting of European sites for global studies. AIBILI also offers a full-service reading center (CORC) providing all imaging assessments typically required in retina clinical trials.
• USRetinaminorStrategic or Co-development PartnerStrategic partnership providing access to expanded resources and wider patient pools for clinical trials through USRetina's network of retina specialists and research sites.
• The Macula SocietyminorOthersInternational association of leading investigators and clinicians in the field of retinal diseases, founded in 1977 by Dr. Lawrence Singerman. Provides forum for knowledge sharing and collaboration in retina research.
• The Retina SocietyminorOthersProfessional medical society focused on retinal diseases, with members including leading retina specialists who participate in clinical trials.
• Ophthalmology Innovation Source (OIS)minorOthersIndustry association focused on ophthalmology innovation and networking within the eye care and clinical research community.
• American Academy of Ophthalmology (AAO)minorOthersLargest professional association for ophthalmologists in the United States, providing continuing education and industry standards.
• American Society of Retina Specialists (ASRS)minorOthersProfessional society for retina specialists, hosting annual meetings and providing educational resources for the retina research community.

Scale indicators6 records

Recent moves7 records

Expansion highlights6 records

Broad incumbents

• Worldwide Clinical Trials: Worldwide Clinical Trials is a mid-size global CRO with deep ophthalmology experience, including retina trials, serving biotech and pharma sponsors. It is comparable to InFocus in therapeutic focus but operates with broader therapeutic area coverage and larger scale.
• IQVIA: IQVIA is the largest global CRO and life sciences services provider, with therapeutic area coverage spanning ophthalmology including retina programs. While not retina-specialized, IQVIA's scale and dedicated ophthalmology unit compete for the larger end of retina trial engagements.
• PPD (Thermo Fisher Scientific): PPD, now part of Thermo Fisher Scientific, is a major global CRO offering clinical development services across all therapeutic areas including ophthalmology. PPD competes with InFocus on large Phase III retina trials and full-service engagements where scale matters.
• Medpace: Medpace is a mid-to-large full-service CRO with a dedicated ophthalmology therapeutic area team serving global pharma and biotech sponsors. While significantly larger than InFocus and operating across all therapeutic areas, Medpace's ophthalmology franchise competes directly for retina trial work.
• ICON plc: ICON plc is one of the largest global CROs with an established ophthalmology therapeutic area offering full-service clinical development for eye disease programs. As a broad incumbent, ICON competes with InFocus for retina trials, particularly larger Phase III engagements, while serving many other therapeutic areas.

Direct peers

• ORA Clinical: ORA Clinical is a specialty ophthalmology CRO offering clinical trial services, regulatory affairs, and medical device expertise for eye care companies. It is the most direct competitor to InFocus in retina-specific clinical research, serving similar biotech and pharma sponsors.
• Premier Research: Premier Research operates a dedicated ophthalmology franchise providing CRO services for retinal and other eye disease trials. It serves similar biotech and pharma sponsors with comparable clinical and regulatory services, making it a direct specialty CRO peer.
• Statistics & Data Corporation (SDC): SDC is a CRO with deep ophthalmology and data management/biostatistics expertise, providing full-service and functional services for eye disease trials. It is comparable to InFocus in therapeutic specialization and overlap in data management and biostatistics offerings.
• Clinipace Worldwide: Clinipace is a mid-size CRO with established ophthalmology and rare disease experience, providing adaptive trial designs and full-service support. Comparable to InFocus in serving mid-sized biotech sponsors and therapeutic specialization in eye disease.

Emerging players

• Verana Health: Verana Health leverages ophthalmology-specific real-world data (IRIS Registry) to support clinical research and commercial decisions for eye disease programs. While operating a different business model, Verana is comparable to InFocus in retina specialization and could complement or compete for sponsor relationships.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xtwitter.com/InFocusClinical
• LinkedInlinkedin.com/company/infocus-clinical

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about InFocus Clinical Research