What GeneProof does

GeneProof a.s. is a privately held Czech molecular diagnostics company founded in 2005 in Brno by Radek Horváth and Miloš Dendis, scientists who introduced PCR methodology into routine Czech clinical practice. The company designs, manufactures, and sells a portfolio of more than 75 CE IVD certified real-time PCR diagnostic kits, nucleic acid extraction kits, and laboratory instruments across seven diagnostic categories: bloodborne infections, immunocompromised/transplant, sexually transmitted infections, neuroinfections, respiratory infections, antibiotic resistance, and thrombotic mutations. Its flagship myCROBE Fully Automated Solution is a sample-to-result instrument handling 1-36 samples per run with up to 8 multiplexed PCR tests per sample, complemented by croBEE extraction systems and the newly launched croGENE Real-Time PCR System.

GeneProof generates revenue through B2B sales of PCR kits (recurring consumable, one-time per test purchase), extraction kits and accessories, and capital instruments, all sold exclusively via a quote-based model through regional sales managers and a global distributor network of more than 50 partners covering 75+ countries. Approximately 90% of production is exported, with end customers being clinical laboratories, hospitals, public health authorities, and university medical centers. The company achieved EU IVDR Quality Management System certification in January 2023, holds ISO 13485:2016 certification, and merged with American Laboratory Products Company (ALPCO) in 2022 under the NuvinkaDx parent, with Erik M. Allen appointed CEO in April 2023. Distribution was further expanded through a 2023 strategic partnership with Thermo Fisher Scientific for the TaqPath Menu | GeneProof PCR tests.

The business operates approximately 100 employees out of its Brno headquarters, with named regional business managers covering APAC/Africa/CIS, Eastern Europe/Middle East, LATAM/Iberia, Western Europe, and Czech/Slovak markets. GeneProof emphasizes expert technical support with guaranteed 24-hour business-day response, GLP training programs held twice yearly, and broad instrument compatibility (validated on Applied Biosystems, Bio-Rad CFX, Roche LightCycler, Qiagen Rotor-Gene, and others) as a core differentiation against closed-cartridge competitors. Recent strategic moves include the croGENE launch (September 2025), RT-PCR Respiratory Panel 1 with DIANA Biotechnologies (December 2025), and a planned CMV IVDR launch on myCROBE (April 2026).

Name

GeneProof

Legal name

GeneProof a.s.

Website

https://geneproof.com

Company type

Private

Founded year

2005

Operating status

Operating

Headcount range

11–50 employees

Short description

GeneProof is a Czech molecular diagnostics company founded in 2005 that designs, manufactures, and sells CE IVD certified real-time PCR kits, extraction systems, and the myCROBE automated platform for clinical laboratories in more than 75 countries.

Ownership category

akta.pro rank

Product category

Molecular In Vitro Diagnostics

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413), Medical Equipment and Supplies Manufacturing (3391)

SIC

In Vitro & In Vivo Diagnostic Substances (2835), Surgical & Medical Instruments & Apparatus (3841), Wholesale-Medical, Dental & Hospital Equipment & Supplies (5047)

akta.pro primary industry

Molecular Diagnostics (PCR/NAAT/NGS-based IVD) (HLAHAAAD)

akta.pro secondary industries

Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays) (HLAGAIAF), Molecular & Genetic Testing (PCR/NGS/qPCR) (HLAGADAF), Molecular Diagnostics (PCR/qPCR, NGS-based assays) (HLAAALAA)

Keywords

• Molecular diagnostics kits
• PCR diagnostic reagents
• Automated PCR systems
• Clinical microbiology diagnostics
• Nucleic acid extraction

Headquarters

HQ city

Brno

HQ country

Czechia

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Supply Chain, Others

Revenue model

1. PCR Diagnostic Kits: GeneProof manufactures and sells a wide portfolio of CE IVD certified PCR kits across 7 diagnostic categories: Bloodborne Infections, Immunocompromised/Transplant, Sexually Transmitted Infections, Neuroinfections, Respiratory Infections, Antibiotic Resistance, and Thrombotic Mutations. Kits are sold as one-time purchases (unit pricing per test), with ready-to-use format requiring no reagent preparation. Over 75 products distributed to more than 75 countries.
2. Nucleic Acid Extraction Kits and Accessories: Extraction kits (croBEE 101A Whole Blood DNA Extraction Kit, croBEE 201A Nucleic Acid Extraction Kit, PathogenFree DNA/RNA Isolation Kits, myCROBE/croBEE 2.0 Universal Extraction Kit) and accessories (pretreatment tubes, tips, PCR plates, seals, waste bins). Sold alongside PCR kits as consumable recurring purchases.
3. Laboratory Instruments: Sale of laboratory equipment including myCROBE fully automated instrument, croBEE 2.0 Nucleic Acid Extraction System, croBEE NA16 Nucleic Acid Extraction System Plus, croBEE Real-Time PCR System, and croGENE Real-Time PCR System. Instruments sold alongside third-party equipment from Biosan and Alpina (bioreactors, laminar flow cabinets).
4. Distribution of Third-Party Products: GeneProof acts as a distributor for the RT-PCR Respiratory Panel 1 from DIANA Biotechnologies, enabling laboratories to access a multiplex respiratory panel (Influenza A/B, RSV, SARS-CoV-2) through GeneProof's distribution network.

Pricing tiers

Go-to-market motion3 records

Distribution channels5 records

Marketing channels9 records

Core offering

GeneProof develops, manufactures, and sells real-time PCR-based molecular in vitro diagnostic kits and instruments for clinical laboratories, hospitals, and public-health institutions. Its offerings span more than 75 CE IVD-certified PCR kits across seven disease categories (bloodborne infections, immunocompromised/transplant, sexually transmitted infections, neuroinfections, respiratory infections, antibiotic resistance, and thrombotic mutations), the myCROBE fully automated sample-to-result instrument, croBEE and croGENE real-time PCR systems, nucleic acid extraction systems, and consumables — sold through a global distributor network and direct sales teams in over 75 countries.

Product overview

GeneProof is a molecular in vitro diagnostics company offering a comprehensive portfolio of PCR-based diagnostic products. The portfolio consists of three integrated pillars: (1) the myCROBE Fully Automated Solution - a sample-to-result automated system comprising the myCROBE instrument with dedicated IT PCR Kits (CMV, EBV, BKV, JCV, HSV, HHV-6/7, HHV-8, VZV), STI PCR Kits (CT, NG, MG, MH, UU, UP, TV, GV), and Thrombotic PCR Kits (FII, FV, FXIII, MTHFR, PAI-1); (2) Manual PCR kits organized by disease category including Bloodborne Infections (HBV, HCV, HIV-1), Immunocompromised/Transplant (CMV, EBV, BKV, JCV, HSV, HHV, VZV, Parvovirus B19), Sexually Transmitted Infections (CT, NG, MG, MH, UU, UP, TV, GV, TP, HPV), Respiratory Infections (Respiratory Panel 1, Flu, SARS-CoV-2, Bordetella, Chlamydia pneumoniae, Legionella, Mycoplasma, TB), Neuroinfections (Borrelia, BK/JC, HSV, VZV), Thrombotic Mutations (FII, FV, FXIII, MTHFR, PAI-1), and Antibiotic Resistance (VRE); and (3) Extraction systems including croBEE 2.0 and NA16 Nucleic Acid Extraction Systems, croBEE and croGENE Real-Time PCR Instruments, and associated extraction and control kits. All products are CE IVD certified with IVDR compliance. GeneProof was founded in 2005 in Czech Republic and merged with ALPCO in 2022.

Differentiator

Problem solved

Functional benefit

Brands

• myCROBE®: Fully automated sample-to-result solution for molecular diagnostics.
• croBEE®
• croGENE®
• PathogenFree®

Products and services

• myCROBE Fully Automated Solution Fully automated sample-to-result molecular diagnostic instrument that processes 1-36 samples per run with up to 96 tests per run, integrating nucleic acid extraction, PCR setup and automated analysis using magnetic particle-based extraction and bidirectional LIS connectivity via HL7 and ASTM protocols. Designed for clinical microbiology and genetics laboratories.
• croBEE 2.0 Nucleic Acid Extraction System Automated high-throughput nucleic acid extraction system for clinical laboratories, CE IVD and IVDR certified, supporting manual or automated DNA/RNA isolation across a range of biological specimen types.
• croBEE NA16 Nucleic Acid Extraction System Plus Automated nucleic acid extraction instrument designed for DNA/RNA isolation from a variety of clinical sample types. IVDR certified.
• croBEE Real-Time PCR System Real-time PCR instrument for clinical molecular diagnostics, IVDR certified, designed for use with GeneProof PCR kits and validated for open-platform workflows.
• croGENE Real-Time PCR System High-performance open-platform real-time PCR instrument launched in 2025 for rapid and reliable molecular diagnostics in clinical laboratories, compatible with GeneProof PCR kits and validated for open workflow use.
• RT-PCR Respiratory Panel 1 Multiplex RT-PCR kit for simultaneous detection of Influenza A, Influenza B, RSV, and SARS-CoV-2 in a single sample. Developed by DIANA Biotechnologies and distributed globally by GeneProof. CE IVD certified under IVDD.
• myCROBE IT Panel Automated myCROBE PCR kit panel for immunocompromised and transplant care diagnostics, detecting CMV, EBV, BKV, JCV, HSV-1/2, HHV-6/7, HHV-8, and VZV with random-access, à la carte multiplexing on the myCROBE instrument.
• GeneProof Hepatitis B Virus (HBV) PCR Kit CE IVD real-time PCR kit for qualitative and quantitative detection of Hepatitis B Virus (HBV) DNA in clinical samples, for professional use in clinical laboratory settings.
• GeneProof Hepatitis C Virus (HCV) Diagnostic PCR Kit CE IVD real-time PCR kit for detection of Hepatitis C Virus (HCV) RNA in clinical samples, for professional use in clinical laboratory settings.
• GeneProof HIV type 1 (HIV-1) Diagnostic PCR Kit CE IVD real-time PCR kit for detection of HIV type 1 (HIV-1) RNA in clinical samples, for professional use in clinical laboratory settings.
• GeneProof Bordetella pertussis/parapertussis PCR Kit CE IVD real-time PCR kit for detection and differential diagnosis of Bordetella pertussis and Bordetella parapertussis, validated on multiple real-time PCR cyclers including Applied Biosystems, BioRad CFX, Roche LightCycler, Qiagen Rotor-Gene, Agilent AriaMx, QuantStudio, BioQuant-96, and QuantGene 9600.
• GeneProof VRE PCR Kit CE IVD real-time PCR kit for detection of Vancomycin-Resistant Enterococci (VRE) in clinical samples, for antibiotic resistance surveillance in clinical microbiology laboratories.
• croBEE 101A Whole Blood DNA Extraction Kit Whole blood DNA extraction kit designed for genomic DNA isolation from whole-blood samples, used with croBEE extraction systems for clinical molecular workflows.
• Good Laboratory Practice (GLP) Training Course Twice-yearly training program held in spring and autumn covering theoretical and practical aspects of molecular biology laboratory procedures using GeneProof products, delivered to laboratory personnel.

Quantifiable outcome

• Up to 108 samples and 270 tests/day processing capacity on myCROBE automated system
• +4 more outcomes

Named customers14 records

Segments8 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration8 records

Feature6 records

Partnerships

Ten partnerships are on record, tiered minor and core.

• DIANA BiotechnologiesminorGTM or Marketing Partner · 16 December 2025GeneProof entered a collaboration with DIANA Biotechnologies to distribute the RT-PCR Respiratory Panel 1, a multiplex test detecting Influenza A, Influenza B, RSV, and SARS-CoV-2 from a single sample. GeneProof acts as the distributor for this CE IVDD product, offering it through its global distribution network. The partnership leverages DIANA's expertise in innovative PCR products and GeneProof's established distribution channels.
• Thermo Fisher ScientificcoreStrategic or Co-development Partner · 17 April 2023ALPCO-GeneProof and Thermo Fisher Scientific announced a strategic partnership in April 2023 to bring the TaqPath Menu | GeneProof PCR tests to market. This partnership leverages Thermo Fisher's global distribution reach for molecular diagnostics products, expanding GeneProof's market access significantly through Thermo Fisher's established commercial channels.
• ALPCO (American Laboratory Products Company, Ltd.)coreStrategic or Co-development Partner · 1 January 2022In 2022, GeneProof merged with American Laboratory Products Company (ALPCO), a specialized in vitro diagnostics company based in Salem, USA. The merger created a global market leader in diagnostic products with broad capabilities including new immunoassay test kits, RT PCR testing products, and automated laboratory instrument solutions. ALPCO distributes GeneProof products in North America. GeneProof's parent company post-merger is NuvinkaDx.
• BiosanminorChannel Partner/ Reseller/ Distributor · 1 January 2021GeneProof partnered with Biosan (European manufacturer of laboratory instruments) beginning in 2021 to offer complementary laboratory equipment including RTS-1C and RTS-8 bioreactors based on Reverse-Spin technology. Biosan focuses on innovations in molecular biology, biochemistry, immunology, and cell biology with over 30 years of R&D tradition.
• AlpinaminorChannel Partner/ Reseller/ Distributor · 1 January 2021GeneProof partnered with Alpina (largest laminar flow cabinet manufacturer in Central Europe) beginning in 2021 to offer complementary laboratory equipment. Alpina manufactures over 20 models of laminar flow and biosafety cabinets certified to EN 12469, combining modern technology, highest quality materials, and precise manufacturing.
• Google (Ads and Analytics)minorOthersGeneProof uses Google Analytics and Google AdWords for website analytics and digital advertising, with a Data Processing Amendment in place per GDPR requirements.
• MailchimpminorOthersGeneProof uses Mailchimp for email marketing and commercial communications, with a Privacy Policy agreement in place per GDPR requirements.
• FacebookminorOthersGeneProof maintains a Facebook company page and uses Facebook's data processing services with a Data Policy agreement in place per GDPR requirements.
• LinkedInminorOthersGeneProof maintains a LinkedIn company page with a Data Processing Agreement in place per GDPR requirements.
• ViaAureaminorOthersViaAurea provides web hosting and digital services for the GeneProof website (www.geneproof.com), with a Privacy Policy agreement in place per GDPR requirements.

Scale indicators9 records

Recent moves7 records

Expansion highlights5 records

Direct peers

• TIB Molbiol: TIB Molbiol (now owned by Roche) is one of the closest direct competitors to GeneProof in PCR-based molecular diagnostic kits for infectious diseases, including respiratory pathogens, HSV, CMV, and a similar ready-to-use master mix design philosophy. Competes head-to-head with GeneProof in the European clinical lab segment.
• Seegene: Seegene is a Korean molecular diagnostics company specializing in multiplex PCR reagents for syndromic testing (respiratory, STI, gastrointestinal). Its high-multiplex technology and broad assay menu directly overlap with GeneProof's STI and respiratory infection product lines.
• Fast Track Diagnostics (Siemens Healthineers): Fast Track Diagnostics, now part of Siemens Healthineers, develops real-time PCR kits for infectious disease and genetic testing with a portfolio and customer base closely aligned to GeneProof's. Both companies target mid-sized clinical laboratories with multiplex and single-plex kits.
• ELITech Group: ELITech Group is a European molecular diagnostics company offering PCR kits, instruments, and extraction systems for infectious disease and genetic testing. Its product range and mid-market positioning directly overlap with GeneProof's portfolio and customer base.

Broad incumbents

• DiaSorin: DiaSorin is a global diagnostics major with a molecular diagnostics franchise (including the Liaison MDX line acquired from Luminex). As a broader incumbent, it competes in the same IVD infectious disease and transplant testing space as GeneProof, but at much larger scale and with a wider product portfolio.
• Cepheid (Danaher): Cepheid, owned by Danaher, sells the GeneXpert closed-cartridge molecular diagnostic system used widely in clinical labs and hospital point-of-care settings. It is a broader incumbent that competes with GeneProof's myCROBE sample-to-result system and PCR kits across infectious disease testing.
• bioMérieux (BioFire): bioMérieux's BioFire FilmArray syndromic panels compete directly with GeneProof's respiratory and STI panels. As a global diagnostics major, bioMérieux offers fully integrated closed-system molecular diagnostics to the same clinical lab customers GeneProof serves.
• QIAGEN: QIAGEN is a major life sciences and molecular diagnostics company whose PCR kits, extraction systems, and QIAstat-Dx platform overlap with GeneProof's product range. Its Rotor-Gene Q and broader instrument portfolio place it in adjacent competition across multiple of GeneProof's disease categories.
• Hologic: Hologic's Panther molecular diagnostics system and Aptima assays serve the same clinical lab and hospital market as GeneProof, particularly in STI and women's health screening. As a broad incumbent with global reach, it competes for the same accounts.

Emerging players

• Promega: Promega supplies nucleic acid extraction chemistries and molecular biology reagents used in clinical and research labs, with emerging clinical diagnostics offerings. While primarily a tools/reagents supplier, it overlaps with GeneProof's extraction and amplification reagent categories and competes for the same laboratory customers.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/GeneProof-as-380982398933950
• LinkedIncz.linkedin.com/company/geneproof-a-s-

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles10 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about GeneProof