AMS Advanced Medical Services

What AMS Advanced Medical Services does

AMS Advanced Medical Services GmbH is a Mannheim-based, privately-held German provider of integrated clinical, regulatory, and commercial services to the pharmaceutical and medical device industries, established circa 1996. The company offers a full-service suite spanning Phase I–III clinical trial operations, Phase IV/non-interventional studies, pharmacovigilance with EU-QPPV support, medical device clinical investigations (including PMCF and IVD studies), market access services (EU HTA, AMNOG benefit assessment, pricing and reimbursement, real-world evidence), Digital Health Applications (DiGA) lifecycle support, recruitment and staffing for healthcare sales, and professional training through its proprietary 1. Internet-Pharmaschule (1.IPS) e-learning platform. Core technology assets include the 1.IPS web-based learning platform (founded 2001 as the first German web-based platform for pharmaceutical sales representative certification, holding DIN ISO 9001:2015, AZAV, and ZFU approvals), a self-hosted Matomo analytics stack, an AI-powered website chatbot for visitor engagement, and TLS 1.2 encrypted internal applicant management infrastructure.

The company monetizes primarily through professional services engagements — full-service or modular clinical research, regulatory affairs, market access, and sales-force staffing delivered via direct B2B relationships to pharmaceutical, biotech, and medical device manufacturers ranging from startups to global enterprises. Training programs generate discrete per-course revenue at publicly listed prices of €1,695 (pharmaceutical sales representative certification) and €1,849 (MSLM course), with 18-month platform access. Distribution occurs through direct enterprise sales, a dedicated freelancer portal (freelanxe-health.de), and a self-service e-commerce training storefront (1ips-shop.ams-europe.com). Publicly disclosed reference customers include B. Braun SE, Bristol Myers Squibb, Roche, STADA, Biotest, Heel, Alimera, Dr. Willmar Schwabe, and Silexion Therapeutics.

AMS has positioned itself as a regulatory specialist, having been a pioneer in German AMNOG benefit assessment since 2010 and an active participant in EU HTA processes since 2015 as a member of EUCOPE; it was an early supporter of Germany's DiGA Fast-Track Procedure beginning in 2020. Ownership is concentrated with Managing Director Dr. Christian Carls (Geschäftsführer); no external venture or private equity capital is evidenced in the data, and the company operates as a standalone GmbH with a single registered office in Mannheim.

Name

AMS Advanced Medical Services

Legal name

AMS Advanced Medical Services GmbH

Website

https://ams-europe.com

Company type

Private

Founded year

1996

Operating status

Operating

Short description

AMS Advanced Medical Services GmbH is a privately-held German CRO and consultancy providing clinical development, regulatory affairs, market access, pharmacovigilance, medical device investigations, DiGA support, healthcare recruitment, and certified pharmaceutical sales training to pharmaceutical, biotech, and medical device companies primarily in Europe.

Ownership category

akta.pro rank

Product category

Contract Research Organization (CRO) and Pharmaceutical Services

NAICS

Scientific Research and Development Services (5417), Research and Development in the Physical, Engineering, and Life Sciences (54171), Other Scientific and Technical Consulting Services (541690)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Health Services (8000), Services-Misc Health & Allied Services, Nec (8090)

akta.pro primary industry

Clinical CROs (Phase I–IV) (HLAGAAAA)

akta.pro secondary industries

Clinical Quality Assurance (GCP QA, TMF/QMS oversight) (HLAGAKAI), Medical Affairs, Scientific Communications & HEOR FSP (HLAGAOAG), Healthcare Clinical Professions (CME/CE for Nurses, Allied Health, Pharmacy) (EDAAALAC), Clinical Research Support (CRC/CTA) (EDAOAJAO)

Keywords

• Contract research services
• Pharmaceutical market access
• Clinical trial management
• Medical device investigations
• Pharmaceutical sales training

Headquarters

HQ city

Baden

HQ country

Germany

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Infrastructure

Revenue model

1. Drug Development & CRO Services: Full-service and modular clinical research services including Phase I-III clinical trials, Phase IV studies, pharmacovigilance, regulatory affairs, medical writing, data management, biostatistics, and clinical safety for pharmaceutical and medical device companies.
2. Medical Devices Services: Clinical investigations for medical devices, post-market clinical follow-up (PMCF) studies, and in-vitro diagnostics consultancy.
3. Market Access & Regulatory Consulting: EU HTA preparation, AMNOG benefit assessment dossiers, pricing and reimbursement strategy, global value dossiers, and routine practice data collection for European market access.
4. Education & Training Programs: Online and self-study training programs for pharmaceutical sales representatives (IHK-certified), Medical Science Liaison Managers, and corporate compliance training (FSA/PHARMIG codes). Revenue generated through course fees (€1,695–€1,849 per course).
5. Recruitment, Staffing & Leasing: Recruitment of specialists and executives for the healthcare market, employee leasing focused on healthcare sales, project-based recruitment and management of field service teams, and freelancer placement.
6. Marketing & Sales Services: Sales and marketing consulting, pilot project implementation, recruitment and management of entire sales teams, and product line marketing for healthcare companies.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

AMS Advanced Medical Services GmbH is a full-service Contract Research Organization (CRO) and pharmaceutical services provider supporting pharmaceutical, biotech, and medical device companies across the product lifecycle. Its core offerings include clinical research services (Phase I-IV trials, pharmacovigilance, EU-QPPV), medical devices clinical investigations, European market access (EU HTA, AMNOG dossiers, pricing and reimbursement, real-world evidence), Digital Health Applications (DiGA), marketing and sales services, recruitment and staffing, and certified training via its proprietary 1. Internet-Pharmaschule (1.IPS) online learning platform.

Product overview

AMS Advanced Medical Services GmbH is a full-service pharmaceutical and healthcare services company with over 29 years of experience. The company operates as a platform of integrated services rather than a single product, encompassing clinical research services (Drug Development Phase I-III, Phase IV, Pharmacovigilance), Medical Devices clinical investigations, Market Access services (EU HTA, AMNOG, Pricing & Reimbursement, Real-World Evidence), Digital Health Applications (DiGA), Marketing & Sales services, Recruitment & Staffing solutions, and Training & Education through its 1. Internet-Pharmaschule (1.IPS) division. The 1.IPS platform provides online certification courses for pharmaceutical sales representatives and Medical Science Liaison Managers. All services are coordinated to support pharmaceutical and medical device products from clinical development through benefit assessment, reimbursement negotiations, and commercialization.

Differentiator

Problem solved

Functional benefit

Brands

• 1. Internet-Pharmaschule (1.IPS): A web-based learning platform founded in 2001 providing online training programs for certified pharmaceutical sales representatives (IHK) and Medical Science Liaison Managers (MSLM). It has DIN ISO 9001:2015 certification and is an approved provider for the promotion of further vocational training according to German AZAV.

Products and services

• Drug Development Services (Phase I-III) Full-service and modular clinical trial support for Phase I-III studies, including Clinical Operations, Regulatory Affairs, Medical Writing, Data Management, Biostatistics, and Clinical Safety services for pharmaceutical manufacturers.
• Phase IV & Pharmacovigilance Late-stage clinical studies including Non-Interventional Studies, Post-Authorization Safety Studies, Evidence Generation Studies, and Pharmacovigilance with EU-QPPV services for pharmaceutical companies.
• Medical Devices Clinical Investigations Clinical investigations for medical devices from early feasibility studies to pivotal studies, including PMCF (Post Marketing Clinical Follow-up) and In-vitro Diagnostics studies for medical device manufacturers.
• Market Access Services (EU HTA, AMNOG) Comprehensive market access support including EU HTA processes, AMNOG benefit assessments, Global Value Dossiers (GVD), HTA Statistics, Pricing & Reimbursement negotiations, and Routine Practice Data Collection (Real-World Evidence) for pharmaceutical and medical device companies seeking European market access.
• Digital Health Applications (DiGA) Support for Digital Health Application lifecycle management including clinical investigations, CE certification, Fast-Track Procedure, and distribution of DiGA products in Germany for digital health application manufacturers.
• Marketing & Sales Services Sales and marketing consulting, pilot project implementation, recruitment and management of sales teams, and marketing of complete product lines for healthcare companies.
• Recruitment, Staffing & Leasing Recruitment of specialists and executives for healthcare market, employee leasing focused on healthcare sales, project-based services for complete field service teams, and freelancer placement via the freelanxe-health.de portal.
• 1. Internet-Pharmaschule (1.IPS) Web-based online learning platform providing self-study and supervised courses for IHK-certified pharmaceutical sales representatives (€1,695 per course), Medical Science Liaison Managers (€1,849 per course), FSA/PHARMIG pharma code compliance training, and corporate training programs with 18-month access.

Quantifiable outcome

• Successfully supports regulatory submissions to Israel Ministry of Health and EU (BfArM Scientific Advice) for client clinical trials.
• +1 more outcomes

Named customers9 records

Segments5 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

One partnership is on record.

• Silexion Therapeutics CorpcoreImplementation/ SI/ Consulting Partner · 4 September 2025AMS Advanced Medical Services GmbH was selected by Silexion Therapeutics Corp as its CRO (Contract Research Organization) partner to support upcoming Phase 2/3 clinical trials for SIL204, a next-generation siRNA candidate targeting KRAS-driven solid tumor cancers. The partnership supports planned regulatory submissions to Israel's Ministry of Health in Q4 2025 and the EU in Q1 2026. Phase 2/3 trials evaluating SIL204's dual-route administration strategy for locally advanced pancreatic cancer were expected to commence in H1 2026. Silexion's preclinical data showed SIL204 demonstrated up to 97% inhibition rates in pancreatic cancer cells and activity across eight KRAS mutations and four cancer types.

Scale indicators3 records

Recent moves5 records

Expansion highlights5 records

Regional players

• GKM Gesellschaft für Therapieforschung mbH: Munich-based CRO providing clinical trial management, monitoring, and regulatory services in Germany. Comparable to AMS in German regional CRO positioning and Phase I-IV clinical research services.
• Dr. Wilke GmbH (MAWOS): Germany-based CRO focused on clinical trials and pharmacovigilance. Strong regional overlap with AMS in the German-speaking market and comparable service mix across clinical development and post-marketing safety.

Direct peers

• TFS International (TFS HealthScience): European-headquartered mid-size CRO providing clinical development, clinical operations, and FSP services. Comparable to AMS as a European-focused mid-market CRO with similar client segments and integrated service offerings.
• Clinipace Worldwide: Mid-sized CRO with European presence offering clinical research, biostatistics, and regulatory services. Comparable to AMS in serving mid-market pharma/biotech sponsors across clinical development and regulatory affairs.
• FGK Clinical Research: European (Munich-based) CRO offering Phase I-IV clinical trial services and regulatory support. Direct peer to AMS in geographic footprint, mid-market positioning, and European clinical/market access service profile.
• Worldwide Clinical Trials: Mid-tier global CRO focused on complex Phase I-IV trials across multiple therapeutic areas. Comparable to AMS in targeting mid-market sponsors needing boutique-style service with global reach.
• Medpace Holdings: Mid-sized, science-focused CRO with strong European presence and full-service Phase I-III capabilities. Closely comparable to AMS in targeting mid-market biotech and pharma sponsors with integrated clinical and regulatory services, though larger in scale.

Broad incumbents

• IQVIA: Largest global CRO and life science services provider with extensive Phase I-IV capabilities, real-world evidence, and market access consulting. Comparable to AMS across clinical research and EU HTA/AMNOG market access service lines, but at vastly greater scale and global reach.
• ICON plc: Major global CRO offering clinical research, biometrics, and consulting services. Directly comparable to AMS's Phase I-IV and medical device clinical investigation offerings, with growing European market access capabilities that increasingly overlap with AMS.
• Parexel International: Large global CRO with deep regulatory, market access, and pharmacovigilance capabilities in Europe. Comparable to AMS across clinical development and EU HTA/AMNOG services, particularly for European market entry engagements.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/ams-advanced-medical-services

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about AMS Advanced Medical Services