UNC Lineberger

What UNC Lineberger does

UNC Lineberger Comprehensive Cancer Center, founded in 1972, is North Carolina's only public NCI-designated comprehensive cancer center, operating as an integral component of the University of North Carolina at Chapel Hill School of Medicine and affiliated with UNC Health. It functions as a research, clinical care, and training institution serving cancer patients, researchers, and communities across North Carolina. Its service portfolio spans eight research programs, three Centers of Excellence (bladder, endometrial, pancreatic cancer), and more than 20 center initiatives. Funding flows predominantly from the NCI Cancer Center Support Grant (P30 CA016086), the state-funded University Cancer Research Fund, NIH training grants, and sponsored research agreements; revenue from clinical trial management and core facility fee-for-service represents a secondary stream.

Its core technology and service infrastructure comprises shared resources organized into Animal Models, Basic Sciences, Clinical/Translational, Genomics/Proteomics, Population Sciences, and Research Support cores. Key facilities include the Translational Genomics Lab (high-throughput nucleic acid extraction, NGS library preparation, and sequencing at 20,000+ sample scale), the Tissue Culture Facility (400+ cell line repository), Rapid Case Ascertainment (statewide NC Cancer Registry interface supporting 900+ publications), and the MaTRIC project management platform launched in 2022 for population science research. Proprietary assets include the UNCseq targeted DNA sequencing panel and electronic patient-reported outcomes tools integrated into Epic EHR systems and used in global clinical trials. The center's clinical research infrastructure is operationalized through the Clinical Trials Office supporting investigator-initiated and industry-sponsored trials across breast, lung, prostate, sarcoma, and other oncology indications.

Its go-to-market model is sales-led via clinical referrals and community outreach, complemented by academic convening functions. Patient care is delivered through UNC Health facilities across North Carolina, extended statewide through the UNC Lineberger Cancer Network (telemedicine and community physician partnerships). Research services are sold fee-for-service to UNC investigators (subsidized) and external clients, while genomic and bioinformatic tools scale nationally via Epic integration and the OncoPRO initiative (with ASCO and the American Cancer Society) across 20+ health systems. Customer segments are hybrid: cancer patients (clinical care), academic and clinician-scientists (shared resources, training), referring physicians and health systems (specialty referrals and tool adoption), and rural/underserved NC communities (screening and outreach partnerships with organizations such as Kintegra Health and Raleigh Housing Authority).

Name

UNC Lineberger

Legal name

UNC Lineberger Comprehensive Cancer Center

Website

https://unclineberger.org

Company type

Private

Founded year

1972

Operating status

Operating

Headcount range

1,001–5,000 employees

Short description

UNC Lineberger Comprehensive Cancer Center is North Carolina's only public NCI-designated comprehensive cancer center, conducting translational genomics, clinical trials, population science, and community outreach research while delivering cancer care through UNC Health and serving patients, researchers, and communities statewide.

Ownership category

akta.pro rank

Product category

Cancer Research and Treatment

NAICS

Specialty (except Psychiatric and Substance Abuse) Hospitals (622310), Diagnostic Imaging Centers (621512), Colleges, Universities, and Professional Schools (611310)

SIC

Services-Medical Laboratories (8071), Services-Health Services (8000), Services-Specialty Outpatient Facilities, Nec (8093)

akta.pro primary industry

Oncology & Cancer Specialty Hospitals (HLAFAHAC)

akta.pro secondary industries

Ambulatory Oncology Centers (Outpatient Chemo/Radiation) (HLAFABAI), Central Laboratory Services (Core Lab Operations) (HLAGAEAA), Surgical Oncology (HLAKAFAG)

Keywords

• Cancer research
• Clinical oncology
• Translational research
• Clinical trials
• Genomic sequencing

Headquarters

HQ city

Chapel Hill

HQ country

United States

HQ region

North America

Offices4 records

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure

Revenue model

1. Government Research Grants and NCI Funding: UNC Lineberger is an NCI-designated comprehensive cancer center supported by NCI Cancer Center Support Grant P30 CA016086, NIH-funded training grants (T32), and other peer-reviewed cancer-focused research grants. Membership is subject to NCI review and is largely provided to investigators holding NCI or other NIH funding.
2. University Cancer Research Fund (UCRF): State-funded cancer research investment created by the N.C. General Assembly in 2007. Began with $25 million in 2007 and grew to $59.5 million by 2022. Funds discovery, innovation, and delivery of improved cancer care across North Carolina.
3. Clinical Trial Revenue: UNC Lineberger's Clinical Trials Office turns research concepts into operational clinical trials, supporting investigator-initiated and industry-sponsored trials. Revenue is generated through clinical research management services, per-trial accruals, and industry sponsorship agreements.
4. Shared Resource Service Fees: Core facilities (Tissue Culture, Translational Genomics Lab, Bioinformatics, etc.) provide services to UNC researchers and external clients on a fee-for-service basis, subsidized for UNC Lineberger members. Services include genomic sequencing, cell line repositories, imaging, and analytical support.
5. Rapid Case Ascertainment Fees: RCA charges fees on a fee-for-service basis for facilitating cancer prevention and control research requiring early patient contact through the North Carolina Central Cancer Registry.

Pricing tiers

Go-to-market motion1 record

Distribution channels5 records

Marketing channels6 records

Core offering

UNC Lineberger is an NCI-designated Comprehensive Cancer Center that conducts basic, translational, and clinical cancer research, delivers multidisciplinary cancer patient care through affiliated clinical facilities, trains the next generation of cancer researchers and clinicians, and operates shared research resources and population health tools. [Inferred from entity name and standard NCI cancer center mission]

Product overview

UNC Lineberger Comprehensive Cancer Center is North Carolina's only public, NCI-designated comprehensive cancer center offering a comprehensive portfolio of cancer research, clinical care, and educational services. The center operates multiple interconnected core facilities and programs including the Translational Genomics Lab (providing genomic sequencing and profiling), Tissue Culture Facility (providing cell lines and reagents), and Rapid Case Ascertainment (enabling early patient recruitment for cancer research). Additional key services include the Clinical Trials Office for operationalizing clinical trials, MaTRIC for population science research project management, Cancer Registry for cancer surveillance data, and the CRTEC training program. The center has developed Patient-Reported Outcomes electronic tools now integrated into Epic EHR systems. Shared Resources span Animal Models, Basic Sciences, Clinical/Translational, Genomics/Proteomics, Population Sciences, and Research Support cores serving the research community.

Differentiator

Problem solved

Functional benefit

Products and services

• Cancer Clinical Trials Program Conducts investigator-initiated and cooperative-group oncology clinical trials for cancer patients across multiple disease sites.
• Translational Genomics Lab Shared resource providing next-generation sequencing and molecular profiling services for cancer researchers.
• Tissue Culture Facility Shared resource providing cell culture, hybridoma, and monoclonal antibody production services for cancer investigators.
• Rapid Case Ascertainment (RCA) Service that rapidly identifies and recruits eligible cancer patients into research studies using the UNC Cancer Registry.
• Cancer Information & Population Health Resource (CIPHR) Resource linking cancer registry data with administrative, claims, and clinical data for population-based cancer outcomes research.
• UNC Cancer Registry Central cancer registry covering North Carolina that collects and manages cancer incidence data for surveillance and research.
• Cancer Research Training & Education Coordination (CRTEC) Coordinates cancer-relevant training programs for students, postdoctoral fellows, and early-career investigators.

Quantifiable outcome

• Patient-reported outcome tools improved clinicians' awareness of patient symptoms and accelerated care, leading to better symptom control, improved quality of life, fewer hospitalizations, and longer survival for cancer patients
• +4 more outcomes

Named customers7 records

Segments4 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

AI capability5 records

Feature6 records

Partnerships

Eleven partnerships are on record, tiered core and minor.

• ZERO Prostate CancercoreStrategic or Co-development Partner · 1 January 2026UNC Lineberger received a 2026 Bayer Community Innovation Grant from ZERO Prostate Cancer to expand prostate cancer screening in rural North Carolina through the Check & Protect: UNC Prostate Cancer Awareness and Screening Initiative. This community-based pilot program aims to expand education, screening, and early detection among men at increased risk. UNC Lineberger was one of only five organizations nationwide selected.
• Strides for Sarcoma FoundationcoreStrategic or Co-development PartnerAwarded $40,000 Maia James Sarcoma Innovation Grant to Pengda Liu for developing novel antibody-drug conjugates to facilitate clinical translation of new targeted therapies for sarcoma.
• Prostate Health Education Network (PHEN)coreStrategic or Co-development PartnerUNC Department of Urology and UNC Lineberger provided clinical leadership for statewide prostate cancer awareness initiatives, supporting PHEN-organized rallies and community health events focused on education, awareness, and early detection across North Carolina.
• Kintegra HealthcoreStrategic or Co-development PartnerCommunity health center partner that launched 'Mega Day' events bringing cancer screening services together in family-friendly, convenient locations close to where patients live, improving access to preventive health services.
• Raleigh Housing AuthorityminorStrategic or Co-development PartnerPartnered with UNC Lineberger Community Outreach and Engagement office to host Health and Wellness Fairs offering cancer education, prostate cancer screenings, and preventive health resources to nearly 50 community members.
• North Carolina Central Cancer Registry (CCR)coreStrategic or Co-development PartnerRCA is a collaboration between UNC Lineberger, the North Carolina Central Cancer Registry, and participating hospitals. CCR accelerates reporting for quick identification of cancer patients throughout the state, enabling early patient contact for prevention and control research.
• American Society of Clinical Oncology (ASCO)coreStrategic or Co-development PartnerUNC Lineberger partners with ASCO as part of the OncoPRO national initiative to provide health systems with training, patient education materials, and technical support for implementing PRO tools in cancer care.
• American Cancer SocietycoreStrategic or Co-development PartnerPartner in OncoPRO initiative alongside ASCO to implement patient-reported outcome tools across US health systems, improving symptom tracking and cancer care outcomes.
• OncoPRO Participating Health SystemscoreStrategic or Co-development PartnerMore than 20 health systems across the US, including UNC Health, East Carolina University, Wake Forest University, and Duke University, are implementing PRO tools through the OncoPRO initiative led by UNC Lineberger.
• UNC HealthcoreStrategic or Co-development PartnerUNC Health is the affiliated health system providing inpatient and outpatient cancer treatment services. UNC Lineberger is the cancer center embedded within UNC School of Medicine, with patient care delivered through UNC Health facilities.
• Epic SystemscoreTechnology or IntegrationPatient-reported outcome tools developed by UNC Lineberger are now integrated into Epic electronic health record systems and available for use by health systems across the United States and Europe.

Scale indicators14 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Duke Cancer Institute: NCI-designated Comprehensive Cancer Center at Duke University, also located in North Carolina's Research Triangle. Directly comparable as an academic comprehensive cancer center delivering oncology research, clinical trials, and patient care in the same geographic market.
• Wake Forest Baptist Comprehensive Cancer Center: NCI-designated Comprehensive Cancer Center at Atrium Health Wake Forest Baptist. Peer academic cancer center competing for the same North Carolina patient population, faculty, and pharma-sponsored trials.
• Winship Cancer Institute of Emory University: NCI-designated Comprehensive Cancer Center in the Southeast US. Comparable as an academic cancer center with research programs, shared resources, clinical trials, and community outreach in a similar regional academic setting.
• Vanderbilt-Ingram Cancer Center: NCI-designated Comprehensive Cancer Center at Vanderbilt University Medical Center. Compares closely in research program structure, translational genomics, clinical trial infrastructure, and academic medical center affiliation.

Regional players

• UNC Lineberger Cancer Network affiliate cancer centers (e.g., East Carolina University, Coastal Carolina): Regional oncology partners across North Carolina that coordinate cancer care and clinical trial access through the UNC Lineberger Cancer Network, extending the center's reach to underserved communities.

Broad incumbents

• MD Anderson Cancer Center: The largest NCI-designated Comprehensive Cancer Center in the US, operating at a much larger scale. Comparable in NCI designation, research breadth, and clinical-trial volume, but far larger and more national in reach.
• Memorial Sloan Kettering Cancer Center: NCI-designated Comprehensive Cancer Center with deep translational research, genomic profiling, and clinical trial capabilities. Comparable scope of basic, translational, and clinical oncology research, though at substantially larger scale.
• Sidney Kimmel Cancer Center (Johns Hopkins): NCI-designated Comprehensive Cancer Center with extensive translational genomics, clinical trials, and research programs. Comparable research breadth but operates at a substantially larger national scale.
• Fred Hutchinson Cancer Center: NCI-designated Comprehensive Cancer Center with strong translational science, clinical trial infrastructure, and population-based research. Comparable research scope and NCI designation, though with a different structural affiliation (independent research center).
• UCSF Helen Diller Family Comprehensive Cancer Center: NCI-designated Comprehensive Cancer Center combining translational research, precision oncology, and clinical trials within a major academic medical center. Comparable in NCI designation and research breadth, but anchored in a different regional market.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/profile.php?id=61573824271489
• LinkedInlinkedin.com/company/unc-lineberger-comprehensive-cancer-center
• Xx.com/unc_som

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about UNC Lineberger