SiteBridge Research

What SiteBridge Research does

SiteBridge Research, Inc. is a private Integrated Research Organization (IRO) founded in 2021 and headquartered in Chapel Hill, North Carolina. The company builds and operates a national network of community-based physician practices — currently 96 sites across 10 states, 271 providers, and an estimated 464,000 reachable patients, with 67% of sites serving rural communities — that delivers industry-sponsored clinical trials on behalf of pharmaceutical companies, biotech firms, medical device manufacturers, and CROs. SiteBridge was established in collaboration with Health2047, the innovation and commercialization subsidiary of the American Medical Association (AMA), which serves as its founding strategic investor.

The company's core product surface centers on 'Trial in a Box™', a turnkey bundle of standardized technologies, SOPs, and research-experienced support staff designed to remove operational and administrative burden from community physicians new to clinical research. It is complemented by a Feasibility Request intake portal for sponsors, a bilingual (English/Spanish) Clinical Trials Toolkit for community education, and a 'Clinical Research as a Care Option' program that equips physicians to offer trials as part of routine care. The model relies on a core set of technologies and SOPs maintained across the network for consistency and quality, while leveraging decentralized and hybrid trial capabilities to reach underserved populations.

SiteBridge makes money by contracting with pharmaceutical sponsors to deliver clinical trials through its site network, receiving fair-market-value compensation for services spanning business development, feasibility, budgets and contracting, training, regulatory document collection, site start-up, patient recruitment and screening, data collection and submission, adverse event reporting, and audit support. The go-to-market combines direct enterprise sales to pharma/CROs (via website feasibility requests and outreach) with a community-led motion that recruits and onboards community physicians, hospitals, FQHCs, and specialty practices. The company is led by CEO & Co-Founder Chris Komelasky and Co-Founder & Board Member Dr. Manesh Patel (Chief of Cardiology at Duke University School of Medicine).

Name

SiteBridge Research

Legal name

SiteBridge Research, Inc.

Website

https://sitebridgeresearch.com

Company type

Private

Founded year

2021

Operating status

Operating

Headcount range

1–10 employees

Short description

SiteBridge Research is an Integrated Research Organization (IRO) that operates a national network of 96 community-based physician practices across 10 states to deliver industry-sponsored clinical trials for pharmaceutical companies and CROs, with a focus on underserved and rural patient populations.

Ownership category

akta.pro rank

Product category

Clinical Research Services

NAICS

Scientific Research and Development Services (5417), Other Scientific and Technical Consulting Services (541690)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Clinical Trial Site Operations & Study Coordination (HLAGACAE)

akta.pro secondary industries

Patient Recruitment, Site Feasibility & Trial Enablement CROs (HLAGAAAI), Clinical Site Start-Up & Activation (Regulatory/Ethics/Contracts) (HLAGACAC)

Keywords

• Clinical research services
• Integrated research organization
• Clinical trial site network
• Community-based trials
• Decentralized clinical trials

Headquarters

HQ city

Chapel Hill

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Others

Revenue model

1. Clinical Trial Support Services: SiteBridge helps sites within its network contract with pharmaceutical companies for specific clinical trials and then supports the administration and delivery of those trials at the sites. Both the site and SiteBridge receive fair market value compensation for their respective activities during the trials.
2. Site Network Management: Revenue generated from supporting clinical research operations including business development, feasibility, budgets and contracting, training, site visits, regulatory document collection, site start-up, patient recruitment and screening, data collection and submission, adverse event reporting, audit support, and study close-out support.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

SiteBridge Research operates as an Integrated Research Organization (IRO) that connects pharmaceutical sponsors and CROs with a national network of community-based physician practices to deliver industry-sponsored clinical trials. It provides Trial in a Box™, a turnkey solution bundling technology, processes, and research-experienced support staff, plus feasibility services, network management, and community engagement resources aimed at increasing diversity in clinical research.

Product overview

SiteBridge Research is an Integrated Research Organization (IRO) that operates as a single unified platform for clinical trial management. The core offering consists of the SiteBridge Network—a national network of community-based physician practices—and the Trial in a Box™ solution, which provides turnkey technology, processes, and experienced support staff. Additional services include the Clinical Trials Toolkit (educational resources in English and Spanish), Feasibility Request services for sponsors, and the Clinical Research as a Care Option program that enables physicians to offer trials as part of routine care.

Differentiator

Problem solved

Functional benefit

Brands

• Trial in a Box™: A turnkey solution of best-in-class technologies, processes, and research experienced support staff that removes burden for patients, physicians and site teams making it easier to take part in clinical trials.

Products and services

• SiteBridge Research Integrated Research Organization (IRO) Services Integrated Research Organization (IRO) services that connect physicians and their patients to clinical trials, reducing barriers for sites and participants through a national network of community-based practices delivering industry-sponsored clinical research on time and on budget.
• Trial in a Box™

Quantifiable outcome

• 71% of patients who participate in clinical trials do so because their doctor recommended it
• +2 more outcomes

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators7 records

Recent moves2 records

Expansion highlights5 records

Direct peers

• Flourish Research: Flourish Research operates a community-based integrated research organization network. Comparable peer in the community-IRO category serving pharma sponsors with multi-specialty sites.
• DM Clinical Research: DM Clinical Research is a community-based SMO with a network of investigator sites. Comparable peer in community site management and patient recruitment services.
• Velocity Clinical Research: Velocity operates a large dedicated site network focused on community-based trial delivery. Most directly comparable peer in the community-site-network category, with similar value proposition to SiteBridge.
• Headlands Research: Headlands Research is an integrated clinical research site network focused on community and diverse patient recruitment. Closely comparable to SiteBridge in target patient population and network-based delivery model.

Broad incumbents

• WCG (WIRB-Copernicus Group): WCG provides central IRB, site support, and clinical trial enablement services. Overlapping capabilities in site activation, regulatory, and trial operations support that compete for sponsor budget.
• IQVIA: IQVIA is the largest global CRO/SMO with extensive site network and patient recruitment capabilities. SiteBridge competes for the same pharma sponsor budget but at a smaller, community-focused scale.
• Syneos Health: Syneos Health operates a global CRO and dedicated site network (Syneos Health Clinical Solutions). Comparable business model of combining site operations with sponsor relationships, though at much larger scale.

Emerging players

• Cliniverse/Clinixir: Cliniverse is an emerging clinical trial technology platform supporting decentralized trials and community site enablement. Comparable in technology-enabled community trial delivery approach.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xtwitter.com/sitebridgeresearch
• LinkedInlinkedin.com/company/sitebridge-research/posts/?feedView=all

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments1 record

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about SiteBridge Research