Dynamic Biosensors
Dynamic Biosensors (now Bruker Biosensors) develops biophysical instruments for molecular interaction analysis using proprietary switchSENSE DNA nanolever and scIC single-cell cytometry technologies, serving pharmaceutical, biotechnology, and academic researchers in drug discovery applications.
- Company typePrivate
- Founded2012
- HeadquartersMunich, Germany
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Dynamic Biosensors does
Dynamic Biosensors, operating as Bruker Biosensors since its October 2024 acquisition by Bruker Corporation, develops biophysical instruments for molecular interaction analysis built on two proprietary technology platforms: switchSENSE, which uses electrically controllable DNA nanolevers attached to gold microelectrodes, and single-cell Interaction Cytometry (scIC/RT-IC), which measures binding kinetics directly on living cells. The product portfolio spans the heliX and heliX+ biosensor instruments (with dual-color detection and multiplexing capabilities), the heliXcyto instrument for real-time interaction cytometry on cells, and the proFIRE system for protein-DNA conjugate preparation and purification, all unified under the heliOS software platform (switchCONTROL, switchBUILD, switchANALYSIS) and supported by proprietary consumable chips, adapter strands, and reagents. The technology is supported by more than 80 peer-reviewed publications covering applications from PROTAC ternary kinetics and bispecific antibody profiling to RNA in vitro evolution and SARS-CoV-2 binding characterization.
The company primarily serves pharmaceutical and biotechnology companies engaged in drug discovery (including novel therapeutic modalities such as PROTACs and bispecific antibodies), with academic and research institutions and government research bodies as secondary segments. Documented users include the Kolmar Group at TU Darmstadt, the Rothemund lab at Caltech, the Hoffmann/Kath-Schorr lab (RNA research), and the Fraunhofer Institute for Cellular Therapies and Immunology (IZI-BB).
The business model follows a classic tools-and-consumables structure: high-value capital equipment sales (heliX, heliX+, heliXcyto, proFIRE instruments) generate initial revenue, followed by recurring revenue from proprietary chips, conjugation kits, and reagents required for ongoing operation. Go-to-market combines enterprise field sales with a demo-led evaluation program (instruments brought to customer labs for hands-on testing), inside sales operations, a dedicated e-commerce shop for consumables, active conference exhibition presence, and a recurring scientific webinar series. International reach is achieved through direct offices in Munich (HQ), Billerica MA (US), and Glasgow (UK), supplemented by distribution partners across Poland, China, Japan, Singapore, and South Korea.
Dynamic Biosensors firmographics
Firmographics- Name
- Dynamic Biosensors
- Legal name
- Bruker Dynamic Biosensors, Zweigniederlassung der Bruker Daltonics GmbH & Co. KG
- Website
- https://dynamic-biosensors.com
- Company type
- Private
- Founded year
- 2012
- Operating status
- Acquired
- Headcount range
- 11–50 employees
- Short description
- Dynamic Biosensors (now Bruker Biosensors) develops biophysical instruments for molecular interaction analysis using proprietary switchSENSE DNA nanolever and scIC single-cell cytometry technologies, serving pharmaceutical, biotechnology, and academic researchers in drug discovery applications.
- Ownership category
- akta.pro rank
Dynamic Biosensors industry classification
Industry- Product category
- Biophysical Research Instruments
- NAICS
- Analytical Laboratory Instrument Manufacturing (334516), Other Measuring and Controlling Device Manufacturing (334519)
- SIC
- Laboratory Analytical Instruments (3826), Industrial Instruments For Measurement, Display, And Control (3823)
- akta.pro primary industry
- Biosensors & Lab-on-Chip (BioMEMS) (HDAHALAK)
- akta.pro secondary industry
- Microscopy, Imaging & Flow Cytometry Instruments (HLAGAIAE)
Keywords
Where Dynamic Biosensors is headquartered
LocationHeadquarters
- HQ city
- Munich
- HQ country
- Germany
- HQ region
- Europe
Offices8 records
Markets served
Dynamic Biosensors business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Personnel, Supply Chain, Marketing or Sales, Operations
Revenue model
- Instrument Sales: Sale of biophysical analysis instruments including heliX, heliX+, heliXcyto, DRX, and proFIRE systems. Instruments are high-value capital equipment sold to pharmaceutical/biotech companies and academic institutions.
- Consumables and Chips: Recurring revenue from sale of heliX chips, heliXcyto chips, consumables, and reagents. Consumables are required for ongoing instrument operation and measurements.
- Conjugation Kits and Reagents: Sale of proFIRE conjugation kits, labelling kits, and easy-to-use protocols for protein-DNA conjugate preparation.
Go-to-market motion3 records
Distribution channels4 records
Marketing channels7 records
Dynamic Biosensors product offering
Product offeringCore offering
Dynamic Biosensors develops and manufactures biophysical analysis instruments for molecular interaction studies used in drug discovery and life science research. Its proprietary switchSENSE® platform uses electrically controllable DNA nanolevers on gold microelectrodes to measure kinetics, affinity, and conformational changes, while its single-cell Interaction Cytometry (scIC) technology enables real-time binding measurements on living cells. The product portfolio includes the heliX/heliX+ and heliXcyto instruments, the proFIRE protein-DNA conjugation system, heliOS software, and consumable chips.
Product overview
Dynamic Biosensors offers a unified platform of biosensor instruments and technologies for molecular interaction analysis. The core portfolio consists of the switchSENSE® technology platform (using DNA nanolevers on gold microelectrodes) and scIC (single-cell Interaction Cytometry) for molecule-cell interactions. The heliX®/heliX+ instruments are the primary analytical platforms compatible with switchSENSE®, featuring multi-spot sensing with dual-color detection. The heliXcyto extends capabilities to real-time kinetic measurements on living cells. The proFIRE® system provides dedicated protein-DNA conjugation instruments. These products share the heliOS software ecosystem and are supported by a range of consumable chips. The company was acquired by Bruker Corporation in October 2024, forming the Bruker Biosensors business unit.
Differentiator
Problem solved
Functional benefit
Brands
- Bruker Biosensors: Post-acquisition brand name for the Dynamic Biosensors business unit within Bruker, combining high-throughput SPR portfolio with switchSENSE and scIC technologies.
Products and services
- switchSENSE® Biophysical research technology platform using DNA nanolevers attached to gold microelectrodes for analyzing molecular interactions, enabling measurement of kinetics, affinity, dose response, conformational changes, and enzymatic activity.
- heliX® / heliX+ Biosensor Versatile biosensor instruments compatible with switchSENSE technology for comprehensive biophysical characterization. The heliX+ features dual-color detection with two sensor spots, two lasers, four single-photon detectors, and multiplexing capabilities.
- heliXcyto Biosensor Real-Time Interaction Cytometry (RT-IC) instrument for measuring molecular binding kinetics directly on living cells using single-cell interaction cytometry technology. Features integrated CCD camera, temperature-controlled chip and sample trays, and automated workflow for cell immobilization.
- proFIRE® Conjugation system for preparation, purification, and analysis of protein-DNA conjugates. Features a 2-step workflow combining protein-DNA conjugation with automated purification, including coupling reagents, high-performance purification, and automatic conjugate recognition.
- heliOS Software Software platform for controlling heliX instruments, including switchCONTROL, switchBUILD, and switchANALYSIS modules for experiment control, workflow design, and data analysis.
- heliX Adapter chip Sensor chip compatible with heliX instruments for molecular interaction analysis.
- heliXcyto chip Specialized chip for RT-IC measurements with cell traps suitable for cells from 6 to 25 µm diameter.
- scIC (single-cell Interaction Cytometry) Technology enabling real-time measurement of molecules binding to membrane targets on living cells, combining biophysics and cytometry principles to measure association/dissociation rates, affinity, avidity, and stability directly on cells.
Quantifiable outcome
- RT-IC can detect low-expression molecules down to ~1000 molecules/cell
- +2 more outcomes
Companies that use Dynamic Biosensors
Customer profileNamed customers6 records
Segments2 records
Ideal customer profiles3 records
Dynamic Biosensors technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature6 records
Dynamic Biosensors partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- Fraunhofer Institute for Cellular Therapies and Immunology (IZI-BB)minorCollaborative research project 'CoronaSense' using switchSENSE technology to characterize binding interactions of SARS-CoV-2 spike proteins with receptors, supporting development of anti-viral drugs and diagnostic tests. Published in Nature Scientific Reports 2022.
Scale indicators4 records
Expansion highlights5 records
Dynamic Biosensors competitors and assessment
Company assessmentBroad incumbents
- Bruker Corporation: Bruker is now the parent company of Dynamic Biosensors (Bruker Biosensors business) and also operates the SPR #64 platform. As parent and a broader biophysical instrumentation incumbent, Bruker provides both expansion runway and adjacent competition within its own portfolio.
- Sartorius AG: Sartorius is a major bioprocessing and lab products supplier serving pharma and biotech R&D with a portfolio that includes cell analysis and analytical instrumentation adjacent to molecular interaction workflows.
- Bio-Rad Laboratories: Bio-Rad's life science research segment serves pharma and academic customers with protein interaction and biophysical characterization tools, providing some overlap with switchSENSE affinity and kinetics applications.
- Thermo Fisher Scientific: Thermo Fisher supplies broad analytical instrumentation (including SPR via subsidiary history) and life science reagents serving pharma biotech discovery, making it a broad incumbent with potential overlap on biophysical characterization budgets.
- Agilent Technologies: Agilent produces analytical and life science instrumentation including mass spectrometry and biophysical tools serving pharma biotech customers, making it a broad incumbent with overlapping surface plasmon resonance-adjacent capabilities.
Direct peers
- Cytiva (Biacore): Cytiva's Biacore is the dominant SPR platform for protein interaction kinetics analysis. It directly competes with switchSENSE-based heliX instruments for the same pharma/biotech drug discovery buying centers, though using optical SPR vs. electrical DNA-nanolever detection.
- Nicoya Lifesciences: Nicoya develops benchtop SPR biosensor instruments (e.g., OpenSPR) for molecular interaction analysis targeting academic and biotech researchers, overlapping with switchSENSE's kinetics and affinity use cases.
- Carterra: Carterra's high-throughput SPR (e.g., LSA) and kinetic analysis instruments target antibody and biologics characterization customers in pharma and CROs, directly competing with heliX/heliX+ for molecular interaction analysis workflows.
- Gator Bio: Gator Bio manufactures label-free biosensor instruments (e.g., GatorPrime) for real-time kinetics and antibody screening, competing with heliX instruments for pharma/biotech protein interaction characterization.
Emerging players
- Reichert Technologies: Reichert specializes in surface plasmon resonance and label-free analytical instruments for biomolecular interaction research, providing a niche SPR-focused overlap with switchSENSE technology in academic and pharma environments.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights7 records
Customer concentration
Dynamic Biosensors social profiles
Digital presenceDynamic Biosensors compliance and trust
Trust signalCompliance13 records
Dynamic Biosensors financial estimates
Financial estimateRevenue estimate
Valuation estimate
Dynamic Biosensors leadership team
Management profileNumber of profiles
Profiles7 records
Dynamic Biosensors funding detail
Funding detailFunding overview
Funding rounds3 records
Investors4 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Dynamic Biosensors M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Dynamic Biosensors
What does Dynamic Biosensors do?
Dynamic Biosensors develops and manufactures biophysical analysis instruments for molecular interaction studies used in drug discovery and life science research. Its proprietary switchSENSE® platform uses electrically controllable DNA nanolevers on gold microelectrodes to measure kinetics, affinity, and conformational changes, while its single-cell Interaction Cytometry (scIC) technology enables real-time binding measurements on living cells. The product portfolio includes the heliX/heliX+ and heliXcyto instruments, the proFIRE protein-DNA conjugation system, heliOS software, and consumable chips.
Is Dynamic Biosensors a public or private company?
Dynamic Biosensors is a private company. It is classified as corporate owned and is currently acquired.
When was Dynamic Biosensors founded?
Dynamic Biosensors was founded in 2012. It employs 11 to 50 people.
Where is Dynamic Biosensors based?
Dynamic Biosensors is headquartered in Munich, Germany, in the Europe region.
How does Dynamic Biosensors make money?
Three revenue lines are on record. Instrument Sales are the primary driver. The others are consumables and Chips and conjugation Kits and Reagents.
Who are Dynamic Biosensors's main competitors?
Broad incumbents on record are Bruker Corporation, Sartorius AG, Bio-Rad Laboratories, Thermo Fisher Scientific and Agilent Technologies. Direct peers are Cytiva (Biacore), Nicoya Lifesciences, Carterra and Gator Bio. Reichert Technologies is listed as an emerging player.
Does Dynamic Biosensors have an API?
No public API is recorded for Dynamic Biosensors.
What industry is Dynamic Biosensors in?
Dynamic Biosensors's product category is Biophysical Research Instruments. Its primary akta.pro industry code is HDAHALAK, Biosensors & Lab-on-Chip (BioMEMS), with a secondary code of HLAGAIAE, Microscopy, Imaging & Flow Cytometry Instruments. Its NAICS code is 334516 and its SIC code is 3826.