Bio-Response
Bio-Response Solutions is a family-owned Indiana manufacturer of alkaline hydrolysis and effluent decontamination systems serving pharmaceutical labs, funeral homes, pet crematories, and agricultural operators globally, holding 26 patents and self-describing as the world's leading producer in its niche.
- Company typePrivate
- Founded2006
- HeadquartersPittsboro, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Bio-Response does
Bio-Response Solutions, Inc. is a family-owned, privately held manufacturer of alkaline hydrolysis systems and effluent decontamination systems headquartered and produced at a single facility in Danville, Indiana. The company's core technology is water-based alkaline hydrolysis, which uses controlled water flow, heat, and alkalinity to sterilize tissue waste into a sterile solution of amino acids, peptides, sugars, nutrients, and soap, validated to achieve complete prion destruction. Its proprietary propeller agitation architecture eliminates submerged seals and agitation pumps, claimed to improve long-term reliability versus competing designs.
The company sells four product lines: Alkaline Hydrolysis / Tissue Digester Systems sized from 50kg laboratory units to 10,000kg industrial systems; Effluent Decontamination Systems (EDS) in Thermal Batch, Thermal Continuous Flow, Chemical Batch, Chemical Continuous Flow, and Thermochemical configurations; the Aquamation sub-brand, a water-based alternative to flame cremation for human and pet remains; and the BioLiquidator sub-brand for agricultural mortality management and protein-based material recycling. Customer segments span pharmaceutical and laboratory research facilities (enterprise), funeral homes and crematories (mid-market), pet crematories (SMB), and agricultural and conservation facilities (enterprise), with technical claims including 90% lower energy use than flame cremation, up to 95% energy recovery in thermal continuous flow systems, and validation at BSL-4 facilities.
Bio-Response operates a direct enterprise field sales model with 24/7 emergency service support and Ethernet-based remote troubleshooting, generating revenue primarily through one-time capital equipment purchases supplemented by service and support contracts. The company is family-owned, employs 11-50 people, holds 26 patents across the US, Europe, Asia-Pacific, and a PCT filing, and maintains five trademarks including AQUAMATION. It sells globally through a multilingual website covering seven European languages and markets in the United States, Netherlands, France, Germany, Italy, Poland, and Spain, and self-describes as the world's leading producer of alkaline hydrolysis systems.
Bio-Response firmographics
Firmographics- Name
- Bio-Response
- Legal name
- Bio-Response Solutions, Inc.
- Website
- https://bioresponsesolutions.com
- Company type
- Private
- Founded year
- 2006
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Bio-Response Solutions is a family-owned Indiana manufacturer of alkaline hydrolysis and effluent decontamination systems serving pharmaceutical labs, funeral homes, pet crematories, and agricultural operators globally, holding 26 patents and self-describing as the world's leading producer in its niche.
- Ownership category
- akta.pro rank
Bio-Response industry classification
Industry- Product category
- Biological Waste Treatment Equipment
- NAICS
- Waste Treatment and Disposal (56221)
- SIC
- Laboratory Apparatus & Furniture (3821)
- akta.pro primary industry
- Water & Wastewater Treatment Plant Equipment (Clarifiers, Aeration, Membrane Systems) (IMAHAEAJ)
- akta.pro secondary industry
- Medical / Infectious Waste Treatment & Disposal (Autoclave + Incineration + Final Disposal) (EUAIACAJ)
Keywords
Where Bio-Response is headquartered
LocationHeadquarters
- HQ city
- Pittsboro
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Bio-Response business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Operations, Supply Chain, Technology or R&D, Marketing or Sales
Revenue model
- Equipment Sales: Sale of alkaline hydrolysis systems, effluent decontamination systems, and BioLiquidator units. Systems range from 50kg laboratory units to 10,000kg industrial systems. Revenue generated through one-time capital equipment purchases with potential ongoing maintenance and service contracts.
- Service and Support: 24/7 emergency service, technical support, and troubleshooting assistance via Ethernet connectivity for factory troubleshooting.
Go-to-market motion1 record
Distribution channels2 records
Marketing channels6 records
Bio-Response product offering
Product offeringCore offering
Bio-Response Solutions designs and manufactures water-based, non-combustion systems for biological waste sterilization and reduction. Its portfolio includes alkaline hydrolysis tissue digester systems, effluent decontamination systems (EDS) for liquid waste, Aquamation systems used as an eco-friendly alternative to flame cremation, and the BioLiquidator mortality management system. Systems range from 50 kg laboratory units to 10,000 kg industrial systems and are manufactured at the company's Danville, Indiana facility.
Product overview
Bio-Response Solutions is a family-owned company that makes sustainable, non-burn technologies. The company offers a portfolio of four core product lines: (1) Effluent Decontamination Systems (EDS) for sterilizing and neutralizing liquid waste in pharmaceutical and laboratory settings, available in Thermal Batch, Thermal Continuous Flow, Chemical Batch, Chemical Continuous Flow, and Thermochemical configurations; (2) Alkaline Hydrolysis / Tissue Digester Systems for sterilizing and reducing tissue wastes, offered in multiple sizes from 50kg laboratory units to 10,000kg industrial systems; (3) Aquamation, a water-based alternative to flame cremation for human and pet remains; and (4) BioLiquidator, a mortality management system for protein-based material recycling. All systems are designed for biosafety, energy reduction, and sustainability, with manufacturing based in Danville, Indiana. The company ships more alkaline hydrolysis systems than all other manufacturers combined.
Differentiator
Problem solved
Functional benefit
Brands
- Aquamation: Water-based alternative to flame cremation available for pet and human loved ones.
- BioLiquidator
- EDS (Effluent Decontamination Systems)
Products and services
- Effluent Decontamination Systems (EDS) Systems that sterilize and neutralize liquid waste streams from pharmaceutical, laboratory, and research facilities dealing with potentially contaminated effluents. Configurations include Thermal Batch, Thermal Continuous Flow, Chemical Batch, Chemical Continuous Flow, and Thermochemical variants built from duplex or super-austenitic stainless steels.
- Alkaline Hydrolysis / Tissue Digester Systems Systems that sterilize and reduce tissue wastes using alkaline hydrolysis, producing a 100% sterile end product free of prion proteins. Offered in multiple sizes from 50 kg laboratory units to 10,000 kg industrial systems. Designed for pharmaceutical, laboratory, and research applications.
- Aquamation A gentle, eco-friendly water-based alternative to flame cremation and burial using alkaline hydrolysis. Available for both human and pet remains. Uses 90% less energy than flame cremation and emits no harmful greenhouse gases.
- BioLiquidator Mortality management system that uses alkaline hydrolysis for sterilization and beneficial recycling of almost any type of protein-based material. Safe alternative to burial, composting, incineration, rendering, and landfill disposal. Targeted at agricultural and conservation operations.
Quantifiable outcome
- 90% less energy consumption compared to flame cremation
- +3 more outcomes
Companies that use Bio-Response
Customer profileNamed customers4 records
Segments3 records
Ideal customer profiles3 records
Bio-Response technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature6 records
Bio-Response partnerships and signals
Strategic signalScale indicators5 records
Recent moves5 records
Expansion highlights5 records
Bio-Response competitors and assessment
Company assessmentBroad incumbents
- Getinge: Swedish medical-technology company with a large sterilization and disinfection equipment portfolio serving pharma and life sciences. Comparable at the customer level (BSL-3/4 labs, vaccine manufacturers), though product overlap is partial.
- Bioquell (Ecolab): Ecolab-owned provider of bio-decontamination systems using hydrogen peroxide vapor. Competes with BRS's EDS in pharma and research-facility decontamination use cases.
- STERIS plc: Global provider of sterilization and infection control products to pharma, labs, and hospitals. A broad incumbent whose effluent and lab decontamination solutions sit adjacent to BRS's EDS line, though its core focus is broader sterilization.
- Matthews International (Cremation Division): Large public funeral services and cremation equipment manufacturer with end-customer overlap in funeral homes and crematories; competes primarily with BRS's Aquamation line via traditional flame cremation equipment.
Direct peers
- Resomation Ltd: UK-based pioneer of alkaline hydrolysis (resomation) for human cremation. The most direct competitor to Bio-Response's aquamation line and a parallel developer of tissue hydrolysis systems, now operating in select markets where the technology is legalized.
- Matthews Aurora Funeral Homes: Operates the North American licensing program for Resomation alkaline hydrolysis equipment. Comparable to Bio-Response as it offers water-based cremation systems competing for the same funeral home customers in the same legalization map.
- Pet Cremation Services / Pet Aquamation: U.S. pet aquamation service provider offering alkaline hydrolysis for companion animals. Comparable end-use customer (pet crematories) and competes for share of the growing eco-friendly pet aftercare market.
- Hydrol UK: UK manufacturer of alkaline hydrolysis equipment for both human and pet cremation, plus industrial/laboratory tissue digester systems. Direct competitor to Bio-Response's Tissue Digester and Aquamation lines.
Emerging players
- Cremation Systems: U.S. manufacturer of cremation equipment for the pet and human cremation industry. Comparable customer base (funeral homes and pet crematories) but offers traditional flame cremation rather than alkaline hydrolysis.
Regional players
- Cattleman's Resource Inc. U.S. supplier of mortality composting and carcass management solutions for the livestock industry. Adjacent competitor to Bio-Response's BioLiquidator mortality management system, addressing the same agricultural biosecurity pain points with a different technology approach.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights7 records
Customer concentration
Bio-Response social profiles
Digital presenceBio-Response financial estimates
Financial estimateRevenue estimate
Valuation estimate
Bio-Response leadership team
Management profileNumber of profiles
Profiles2 records
Bio-Response funding detail
Funding detailFunding overview
Funding rounds1 record
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Bio-Response M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Bio-Response
What does Bio-Response do?
Bio-Response Solutions designs and manufactures water-based, non-combustion systems for biological waste sterilization and reduction. Its portfolio includes alkaline hydrolysis tissue digester systems, effluent decontamination systems (EDS) for liquid waste, Aquamation systems used as an eco-friendly alternative to flame cremation, and the BioLiquidator mortality management system. Systems range from 50 kg laboratory units to 10,000 kg industrial systems and are manufactured at the company's Danville, Indiana facility.
Is Bio-Response a public or private company?
Bio-Response is a private company. It is classified as family owned and is currently operating.
When was Bio-Response founded?
Bio-Response was founded in 2006. It employs 11 to 50 people.
Where is Bio-Response based?
Bio-Response is headquartered in Pittsboro, United States, in the North America region.
How does Bio-Response make money?
Two revenue lines are on record. Equipment Sales are the primary driver. The others are service and Support.
Who are Bio-Response's main competitors?
Broad incumbents on record are Getinge, Bioquell (Ecolab), STERIS plc and Matthews International (Cremation Division). Direct peers are Resomation Ltd, Matthews Aurora Funeral Homes, Pet Cremation Services / Pet Aquamation and Hydrol UK. Cremation Systems is listed as an emerging player. Cattleman's Resource Inc. is listed as a regional player.
Does Bio-Response have an API?
No public API is recorded for Bio-Response.
What industry is Bio-Response in?
Bio-Response's product category is Biological Waste Treatment Equipment. Its primary akta.pro industry code is IMAHAEAJ, Water & Wastewater Treatment Plant Equipment (Clarifiers, Aeration, Membrane Systems), with a secondary code of EUAIACAJ, Medical / Infectious Waste Treatment & Disposal (Autoclave + Incineration + Final Disposal). Its NAICS code is 56221 and its SIC code is 3821.