Bio-Response

What Bio-Response does

Bio-Response Solutions, Inc. is a family-owned, privately held manufacturer of alkaline hydrolysis systems and effluent decontamination systems headquartered and produced at a single facility in Danville, Indiana. The company's core technology is water-based alkaline hydrolysis, which uses controlled water flow, heat, and alkalinity to sterilize tissue waste into a sterile solution of amino acids, peptides, sugars, nutrients, and soap, validated to achieve complete prion destruction. Its proprietary propeller agitation architecture eliminates submerged seals and agitation pumps, claimed to improve long-term reliability versus competing designs.

The company sells four product lines: Alkaline Hydrolysis / Tissue Digester Systems sized from 50kg laboratory units to 10,000kg industrial systems; Effluent Decontamination Systems (EDS) in Thermal Batch, Thermal Continuous Flow, Chemical Batch, Chemical Continuous Flow, and Thermochemical configurations; the Aquamation sub-brand, a water-based alternative to flame cremation for human and pet remains; and the BioLiquidator sub-brand for agricultural mortality management and protein-based material recycling. Customer segments span pharmaceutical and laboratory research facilities (enterprise), funeral homes and crematories (mid-market), pet crematories (SMB), and agricultural and conservation facilities (enterprise), with technical claims including 90% lower energy use than flame cremation, up to 95% energy recovery in thermal continuous flow systems, and validation at BSL-4 facilities.

Bio-Response operates a direct enterprise field sales model with 24/7 emergency service support and Ethernet-based remote troubleshooting, generating revenue primarily through one-time capital equipment purchases supplemented by service and support contracts. The company is family-owned, employs 11-50 people, holds 26 patents across the US, Europe, Asia-Pacific, and a PCT filing, and maintains five trademarks including AQUAMATION. It sells globally through a multilingual website covering seven European languages and markets in the United States, Netherlands, France, Germany, Italy, Poland, and Spain, and self-describes as the world's leading producer of alkaline hydrolysis systems.

Name

Bio-Response

Legal name

Bio-Response Solutions, Inc.

Website

https://bioresponsesolutions.com

Company type

Private

Founded year

2006

Operating status

Operating

Headcount range

11–50 employees

Short description

Bio-Response Solutions is a family-owned Indiana manufacturer of alkaline hydrolysis and effluent decontamination systems serving pharmaceutical labs, funeral homes, pet crematories, and agricultural operators globally, holding 26 patents and self-describing as the world's leading producer in its niche.

Ownership category

akta.pro rank

Product category

Biological Waste Treatment Equipment

NAICS

Waste Treatment and Disposal (56221)

SIC

Laboratory Apparatus & Furniture (3821)

akta.pro primary industry

Water & Wastewater Treatment Plant Equipment (Clarifiers, Aeration, Membrane Systems) (IMAHAEAJ)

akta.pro secondary industry

Medical / Infectious Waste Treatment & Disposal (Autoclave + Incineration + Final Disposal) (EUAIACAJ)

Keywords

• Alkaline hydrolysis systems
• Effluent decontamination systems
• Aquamation equipment
• Tissue waste sterilization
• Biological waste treatment

Headquarters

HQ city

Pittsboro

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Supply Chain, Technology or R&D, Marketing or Sales

Revenue model

1. Equipment Sales: Sale of alkaline hydrolysis systems, effluent decontamination systems, and BioLiquidator units. Systems range from 50kg laboratory units to 10,000kg industrial systems. Revenue generated through one-time capital equipment purchases with potential ongoing maintenance and service contracts.
2. Service and Support: 24/7 emergency service, technical support, and troubleshooting assistance via Ethernet connectivity for factory troubleshooting.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels6 records

Core offering

Bio-Response Solutions designs and manufactures water-based, non-combustion systems for biological waste sterilization and reduction. Its portfolio includes alkaline hydrolysis tissue digester systems, effluent decontamination systems (EDS) for liquid waste, Aquamation systems used as an eco-friendly alternative to flame cremation, and the BioLiquidator mortality management system. Systems range from 50 kg laboratory units to 10,000 kg industrial systems and are manufactured at the company's Danville, Indiana facility.

Product overview

Bio-Response Solutions is a family-owned company that makes sustainable, non-burn technologies. The company offers a portfolio of four core product lines: (1) Effluent Decontamination Systems (EDS) for sterilizing and neutralizing liquid waste in pharmaceutical and laboratory settings, available in Thermal Batch, Thermal Continuous Flow, Chemical Batch, Chemical Continuous Flow, and Thermochemical configurations; (2) Alkaline Hydrolysis / Tissue Digester Systems for sterilizing and reducing tissue wastes, offered in multiple sizes from 50kg laboratory units to 10,000kg industrial systems; (3) Aquamation, a water-based alternative to flame cremation for human and pet remains; and (4) BioLiquidator, a mortality management system for protein-based material recycling. All systems are designed for biosafety, energy reduction, and sustainability, with manufacturing based in Danville, Indiana. The company ships more alkaline hydrolysis systems than all other manufacturers combined.

Differentiator

Problem solved

Functional benefit

Brands

• Aquamation: Water-based alternative to flame cremation available for pet and human loved ones.
• BioLiquidator
• EDS (Effluent Decontamination Systems)

Products and services

• Effluent Decontamination Systems (EDS) Systems that sterilize and neutralize liquid waste streams from pharmaceutical, laboratory, and research facilities dealing with potentially contaminated effluents. Configurations include Thermal Batch, Thermal Continuous Flow, Chemical Batch, Chemical Continuous Flow, and Thermochemical variants built from duplex or super-austenitic stainless steels.
• Alkaline Hydrolysis / Tissue Digester Systems Systems that sterilize and reduce tissue wastes using alkaline hydrolysis, producing a 100% sterile end product free of prion proteins. Offered in multiple sizes from 50 kg laboratory units to 10,000 kg industrial systems. Designed for pharmaceutical, laboratory, and research applications.
• Aquamation A gentle, eco-friendly water-based alternative to flame cremation and burial using alkaline hydrolysis. Available for both human and pet remains. Uses 90% less energy than flame cremation and emits no harmful greenhouse gases.
• BioLiquidator Mortality management system that uses alkaline hydrolysis for sterilization and beneficial recycling of almost any type of protein-based material. Safe alternative to burial, composting, incineration, rendering, and landfill disposal. Targeted at agricultural and conservation operations.

Quantifiable outcome

• 90% less energy consumption compared to flame cremation
• +3 more outcomes

Named customers4 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Scale indicators5 records

Recent moves5 records

Expansion highlights5 records

Broad incumbents

• Getinge: Swedish medical-technology company with a large sterilization and disinfection equipment portfolio serving pharma and life sciences. Comparable at the customer level (BSL-3/4 labs, vaccine manufacturers), though product overlap is partial.
• Bioquell (Ecolab): Ecolab-owned provider of bio-decontamination systems using hydrogen peroxide vapor. Competes with BRS's EDS in pharma and research-facility decontamination use cases.
• STERIS plc: Global provider of sterilization and infection control products to pharma, labs, and hospitals. A broad incumbent whose effluent and lab decontamination solutions sit adjacent to BRS's EDS line, though its core focus is broader sterilization.
• Matthews International (Cremation Division): Large public funeral services and cremation equipment manufacturer with end-customer overlap in funeral homes and crematories; competes primarily with BRS's Aquamation line via traditional flame cremation equipment.

Direct peers

• Resomation Ltd: UK-based pioneer of alkaline hydrolysis (resomation) for human cremation. The most direct competitor to Bio-Response's aquamation line and a parallel developer of tissue hydrolysis systems, now operating in select markets where the technology is legalized.
• Matthews Aurora Funeral Homes: Operates the North American licensing program for Resomation alkaline hydrolysis equipment. Comparable to Bio-Response as it offers water-based cremation systems competing for the same funeral home customers in the same legalization map.
• Pet Cremation Services / Pet Aquamation: U.S. pet aquamation service provider offering alkaline hydrolysis for companion animals. Comparable end-use customer (pet crematories) and competes for share of the growing eco-friendly pet aftercare market.
• Hydrol UK: UK manufacturer of alkaline hydrolysis equipment for both human and pet cremation, plus industrial/laboratory tissue digester systems. Direct competitor to Bio-Response's Tissue Digester and Aquamation lines.

Emerging players

• Cremation Systems: U.S. manufacturer of cremation equipment for the pet and human cremation industry. Comparable customer base (funeral homes and pet crematories) but offers traditional flame cremation rather than alkaline hydrolysis.

Regional players

• Cattleman's Resource Inc. U.S. supplier of mortality composting and carcass management solutions for the livestock industry. Adjacent competitor to Bio-Response's BioLiquidator mortality management system, addressing the same agricultural biosecurity pain points with a different technology approach.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/bioresponse
• YouTubeyoutube.com/@bio-responsesolutions89
• Facebookfacebook.com/bioresponse
• Instagraminstagram.com/bioresponse
• LinkedInlinkedin.com/company/bio-response-solutions-inc-

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Bio-Response