Human Diagnosis Project
Human Dx operates an open platform combining collective expertise from 100,000+ physicians across 100+ countries with multiple frontier LLMs to synthesize diagnostic insights, serving medical professionals, academic medical centers, and patients via freemium community participation and paid Insights consultative services.
- Company typePrivate
- Founded2012
- HeadquartersSan Francisco, United States
- Headcount11–50
- GTM typeB2B and B2C
- OfferingSoftware
What Human Diagnosis Project does
The Human Diagnosis Project (Human Dx) is a San Francisco-based, Delaware-incorporated private company founded in 2012 that operates an open online platform combining collective medical expertise from 100,000+ physicians across 100+ countries with multiple large language models (Google, OpenAI, Anthropic, Mistral, Perplexity) to produce synthesized diagnostic outputs. The platform's core technology is a hybrid human-AI collective intelligence engine that pools multiple physicians' judgments and AI model outputs into a single cohesive result, with peer-reviewed research validating that this approach raises diagnostic accuracy from 46% to 76% and outperforms both human-only and LLM-only groups across medical specialties. The product suite includes the general community Q&A platform, the Global Morning Report (GMR) for daily clinical reasoning training, the Insights consultative service for physicians and patients, and iOS/Android mobile apps, supported by an Impact points engagement system and an Editorial Board for quality assurance.
Human Dx is structured as a partnership between the social, public, and private sectors, with flagship partners including the American Medical Association, American Board of Medical Specialties, Harvard Medical School, Johns Hopkins, UCSF, MIT, and Berkeley, plus international research collaborators such as the Max Planck Society and the European Commission's funded HACID project. Its go-to-market is primarily community-led and product-led: clinicians self-register via mobile app or website, participate via word-of-mouth among medical professionals, and 500+ academic medical centers and residency programs adopt the platform for training. Revenue comes from a freemium Impact-points knowledge exchange economy and a credit-card-paid Insights subscription tier, supplemented by foundation grants from MacArthur, Moore, the European Commission, and the AMA Foundation, alongside venture capital from Union Square Ventures (lead investor), Andreessen Horowitz, First Round Capital, and Kapor Capital. The company has been recognized with the 2017 MacArthur Foundation 100&Change award and has published validation research in NEJM AI, JAMA Open, JAMA Internal Medicine, and PNAS, positioning itself as the only platform combining global physician collective intelligence with multiple frontier LLMs into a single validated diagnostic output.
Human Diagnosis Project firmographics
Firmographics- Name
- Human Diagnosis Project
- Legal name
- Human Dx, Ltd.
- Website
- https://humandx.org
- Company type
- Private
- Founded year
- 2012
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Human Dx operates an open platform combining collective expertise from 100,000+ physicians across 100+ countries with multiple frontier LLMs to synthesize diagnostic insights, serving medical professionals, academic medical centers, and patients via freemium community participation and paid Insights consultative services.
- Ownership category
- akta.pro rank
Human Diagnosis Project industry classification
Industry- Product category
- Clinical Decision Support
- NAICS
- Custom Computer Programming Services (541511), Other Scientific and Technical Consulting Services (541690)
- SIC
- Services-Prepackaged Software (7372)
- akta.pro primary industry
- Digital & AI-Enabled Diagnostics (algorithmic interpretation, decision support tied to assays) (HLAAALAO)
- akta.pro secondary industries
- DTx/SaMD Evidence, Outcomes & Real-World Data (RWE) Platforms (HLACANAM), Domain-Specific Training Data Solutions (e.g., medical, AV, geospatial) (HDAAALAL)
Keywords
Where Human Diagnosis Project is headquartered
LocationHeadquarters
- HQ city
- San Francisco
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Human Diagnosis Project business model
Business model- GTM type
- B2B and B2C
- Offering type
- Software
- Cost components
- Technology or R&D, Personnel, Operations, Marketing or Sales, Others
Revenue model
- Community Impact Points: Community members earn 'Impact' by answering questions and helping others. Impact are points that can be exchanged for answers to users' own questions within the system. The system creates a self-sustaining knowledge exchange economy.
- Insights Consultative Services: Fee-based consultative services where physicians and patients can access additional information to assist in planning medical care. Credit card payments are the accepted means of payment. This is governed by separate Insights Terms of Service.
Go-to-market motion2 records
Distribution channels3 records
Marketing channels6 records
Human Diagnosis Project product offering
Product offeringCore offering
Human Diagnosis Project (Human Dx) operates an open intelligence platform that combines collective medical expertise from 100,000+ physicians across 100+ countries with multiple top large language models (Google, OpenAI, Anthropic, Mistral, Perplexity) to produce synthesized diagnostic outputs. The platform enables physicians and trainees to ask and answer clinical questions, earn Impact points, and access hybrid human-AI insights, while delivering daily clinical reasoning practice via the Global Morning Report (GMR).
Product overview
Human Diagnosis Project (Human Dx) is a single unified platform combining collective human medical intelligence with machine learning to enable more accurate, affordable, and accessible healthcare. The core platform integrates multiple top AI systems (Google, OpenAI, Anthropic, Mistral, and Perplexity) with expertise from a global community of 100,000+ medical professionals across 500+ institutions in 100+ countries. The platform consists of several integrated components: the general Community platform for asking questions and sharing expertise; the Insights module providing consultative services for physicians and patients; the Global Morning Report (GMR) providing daily clinical case training; and the Human Dx Mobile App (iOS/Android) enabling access on the go. Supporting infrastructure includes the Editorial Board for quality assurance and the Impact System for user engagement. Research published in NEJM AI, JAMA Open, and PNAS validates the platform's hybrid human-AI collective intelligence approach, demonstrating that pooling multiple physicians' diagnoses can raise diagnostic accuracy from 46% to 76%, with AI-human collectives outperforming both human-only and AI-only groups.
Differentiator
Problem solved
Functional benefit
Brands
- Global Morning Report (GMR): A daily clinical reasoning training platform where medical professionals and trainees solve diagnostic cases published each weekday via email and mobile app.
- Insights
Products and services
- Human Dx Core Platform An open online system that maps steps to help any patient by combining collective human medical intelligence from 100,000+ physicians across 100+ countries with machine learning. Enables medical professionals to ask clinical questions, share expertise, and receive synthesized answers integrating multiple top AI systems with expert community insights.
- Insights A consultative service giving physicians and patients access to additional diagnostic information by combining AI systems with medical professional expertise to provide hybrid human-AI collective intelligence for patient care planning. Credit card payments are the accepted means of payment under separate Insights Terms of Service.
- Global Morning Report (GMR) A daily (weekday) case-based training feature where medical professionals and trainees solve clinical vignettes in approximately 2 minutes to build differential diagnosis and clinical reasoning skills. New cases are published via email and in the mobile app with immediate feedback, created and peer-reviewed by physicians from the Human Dx Community and Editorial Board.
- Human Dx Mobile App
Quantifiable outcome
- Pooling physicians' diagnoses raises diagnostic accuracy from 46% to 76% in validated studies.
- +2 more outcomes
Companies that use Human Diagnosis Project
Customer profileNamed customers7 records
Segments4 records
Ideal customer profiles3 records
Human Diagnosis Project technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration6 records
AI capability4 records
Feature4 records
Human Diagnosis Project partnerships and signals
Strategic signalPartnerships
14 partnerships are on record, tiered flagship, core and supporting.
- American Medical Association (AMA)flagshipLeading national medical organization partner of Human Dx. AMA is one of the nation's top medical organizations and contributes to governance, medical standards, and credibility within the physician community.
- American Board of Medical Specialties (ABMS)flagshipPartner organization responsible for physician board certification standards. Collaboration supports integration of Human Dx into continuing certification and competency assessment.
- National Association of Community Health Centers (NACHC)corePartnership to extend collective diagnostic intelligence to community health centers, expanding access to quality care in underserved areas.
- Harvard Medical SchoolflagshipAcademic partner collaborating on research validating human-AI collective intelligence for medical diagnosis. Published findings in peer-reviewed journals including JAMA Open.
- Johns Hopkins School of MedicineflagshipAcademic partner conducting research on physician diagnostic performance and comparative accuracy of collective intelligence vs. individual physicians. Published in JAMA Open and JAMA Internal Medicine.
- UCSF (University of California, San Francisco)flagshipAcademic partner with faculty actively using and endorsing Human Dx. Dr. Robert Wachter, Professor and Chair at UCSF, is a public advocate for the platform.
- MITcoreAcademic partner contributing to the research and development of the Human Diagnosis Project's machine learning and collective intelligence technologies.
- UC BerkeleycoreAcademic partner contributing to the research foundation of Human Dx's collective intelligence and machine learning approaches.
- Max Planck Society (MPI)coreEuropean research partner contributing to the HACID project alongside University of Cologne, Harvey Mudd College, and University of Oxford on human-AI collective intelligence research.
- National Research Council of Italy (CNR)coreEuropean research partner collaborating on human-AI collective intelligence studies.
- NESTAcoreUK innovation foundation partner supporting the development and research of collective intelligence approaches in healthcare.
- American Board of Internal Medicine (ABIM)coreBoard certification body for internal medicine collaborating on standards for physician competency assessment using Human Dx.
- Association of Clinicians in the United States (ACU)supportingPartner representing clinicians, working to expand the use of Human Dx among clinical professionals and trainee populations.
- Met Office (UK)supportingUK government weather service partnered on the HACID project, contributing to collective intelligence research methodologies.
Scale indicators7 records
Recent moves6 records
Expansion highlights6 records
Human Diagnosis Project competitors and assessment
Company assessmentDirect peers
- OpenEvidence: AI-powered clinical decision support platform for physicians that synthesizes medical literature into evidence-based answers. Directly comparable to Human Dx in target customer (clinicians) and core function (AI-augmented diagnostic/clinical reasoning support), though OpenEvidence is more literature-focused while Human Dx emphasizes collective human-AI intelligence.
- Glass Health: AI clinical decision support tool used by physicians for differential diagnosis and treatment planning. Directly competes with Human Dx in providing AI-assisted diagnostic reasoning to clinicians, with a similar physician-centric value proposition.
- Atropos Health: Provides AI-driven clinical evidence generation and decision support for clinicians and health systems using real-world data. Comparable to Human Dx as a clinical decision support platform serving physicians, though Atropos emphasizes real-world evidence queries versus Human Dx's collective intelligence approach.
- Isabel Healthcare: Long-standing differential diagnosis decision support tool used by clinicians worldwide. Directly comparable to Human Dx in providing diagnostic reasoning assistance, though Isabel relies on a curated knowledge base rather than collective physician intelligence and AI synthesis.
- VisualDx: Clinical decision support system focused on visual diagnosis, used by physicians and medical trainees. Comparable to Human Dx as a diagnostic decision support tool for clinicians with training-focused product extensions similar to Global Morning Report.
Broad incumbents
- Doximity: Largest professional network for U.S. physicians with integrated clinical tools including AI-powered documentation and workflow. Adjacent to Human Dx as a broad incumbent physician platform with overlapping clinician audience and increasingly competitive AI clinical features.
- Wolters Kluwer UpToDate: Industry-standard clinical decision support resource used by the majority of U.S. physicians and hospitals. Comparable as a clinical decision support incumbent serving the same clinician customer base, though UpToDate is expert-authored content rather than AI or collective intelligence.
- DynaMed: Evidence-based clinical decision support tool from EBSCO serving physicians and other clinicians. Comparable to Human Dx as a clinical reference and decision support product serving the same clinician segment, though DynaMed is curated expert content.
Emerging players
- Figure 1: Medical case-sharing platform where clinicians discuss real patient cases. Comparable to Human Dx in the peer-to-peer clinical case sharing and learning use case, though Figure 1 is more image-based and lacks the AI synthesis layer.
- Sermo: Online physician community for peer consultation, medical crowdsourcing, and clinical insights. Comparable to Human Dx as a community-led platform for physicians to exchange clinical expertise, though Sermo is primarily a discussion forum without the AI synthesis engine.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
Human Diagnosis Project social profiles
Digital presenceHuman Diagnosis Project financial estimates
Financial estimateRevenue estimate
Valuation estimate
Human Diagnosis Project leadership team
Management profileNumber of profiles
Profiles2 records
Human Diagnosis Project funding detail
Funding detailFunding overview
Funding rounds3 records
Investors5 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Human Diagnosis Project M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Human Diagnosis Project
What does Human Diagnosis Project do?
Human Diagnosis Project (Human Dx) operates an open intelligence platform that combines collective medical expertise from 100,000+ physicians across 100+ countries with multiple top large language models (Google, OpenAI, Anthropic, Mistral, Perplexity) to produce synthesized diagnostic outputs. The platform enables physicians and trainees to ask and answer clinical questions, earn Impact points, and access hybrid human-AI insights, while delivering daily clinical reasoning practice via the Global Morning Report (GMR).
Is Human Diagnosis Project a public or private company?
Human Diagnosis Project is a private company. It is classified as venture growth investor backed and is currently operating.
When was Human Diagnosis Project founded?
Human Diagnosis Project was founded in 2012. It employs 11 to 50 people.
Where is Human Diagnosis Project based?
Human Diagnosis Project is headquartered in San Francisco, United States, in the North America region.
How does Human Diagnosis Project make money?
Two revenue lines are on record. Community Impact Points are the primary driver. The others are insights Consultative Services.
Who are Human Diagnosis Project's main competitors?
Direct peers on record are OpenEvidence, Glass Health, Atropos Health, Isabel Healthcare and VisualDx. Broad incumbents are Doximity, Wolters Kluwer UpToDate and DynaMed. Emerging players are Figure 1 and Sermo.
Does Human Diagnosis Project have an API?
No public API is recorded for Human Diagnosis Project.
What industry is Human Diagnosis Project in?
Human Diagnosis Project's product category is Clinical Decision Support. Its primary akta.pro industry code is HLAAALAO, Digital & AI-Enabled Diagnostics (algorithmic interpretation, decision support tied to assays), with a secondary code of HLACANAM, DTx/SaMD Evidence, Outcomes & Real-World Data (RWE) Platforms. Its NAICS code is 541511 and its SIC code is 7372.