Biochain

What Biochain does

BioChain Institute Inc. is a privately held life sciences research products and services company founded in 1994 and headquartered at 39600 Eureka Drive, Newark, California. The company supplies human biospecimens (FFPE tissue, frozen tissue, DNA, RNA, protein, matched pair tumor/normal samples), nucleic acid extraction kits, automated sample preparation instruments, reference and control standards, and spatial multiomics services to pharmaceutical, biotechnology, academic, and molecular diagnostics customers. BioChain claims to serve the top 500 global pharmaceutical and biotechnology firms and academic leaders and reports that over 3,000 peer-reviewed publications reference its products, signaling deep integration into established research workflows.

The company's core technology centers on proprietary xTractPure magnetic bead-based extraction chemistry, deployed through the AnaPrep 12 Dx (CFR 21 Part 11 compliant for clinical diagnostics) and AnaPrep 48 automated nucleic acid extraction instruments, with FFPE-specific kits that address cross-linking and degradation in archived specimens. BioChain operates certified spatial biology services through partnerships with 10x Genomics (Visium HD whole-transcriptome at 2µm resolution and Xenium Prime 5K single-cell imaging) and NanoString (GeoMx DSP), providing end-to-end workflows from biospecimen sourcing through tissue characterization and multiomic profiling. ISO 9001:2015 certification for OEM manufacturing, ISO certification plus IRB approval for biospecimen operations, and FDA-approved tissue arrays constitute the regulatory foundation underpinning clinical trial and diagnostic customer use cases.

BioChain monetizes through catalog biospecimen and reagent sales at published unit prices, instrument sales ($34,300 for AnaPrep 48), consumable pull-through, and quote-based custom services including spatial multiomics, histology, biospecimen procurement, targeted gene expression profiling, and OEM manufacturing. Distribution is direct via biochain.com for US customers, supplemented by an international distributor network. Named customers include Regeneron, GSK, Roche, Teva, Thermo Fisher Scientific, Harvard University, NIH, and Science Exchange. The company is led by co-founder Zhi Yang and Chief Business Officer Bingfang Huan, with operations spanning the United States and partner-served international markets.

Name

Biochain

Legal name

BioChain Institute Inc.

Website

https://biochain.com

Company type

Private

Founded year

1994

Operating status

Operating

Headcount range

251–500 employees

Short description

BioChain Institute Inc. is a privately held life sciences research products and services company founded in 1994, supplying biospecimens, nucleic acid extraction kits, automated AnaPrep instruments, reference standards, and spatial multiomics services to pharmaceutical, biotechnology, academic, and molecular diagnostics customers globally.

Ownership category

akta.pro rank

Product category

Life Science Research Products

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413), Analytical Laboratory Instrument Manufacturing (334516), Medical Laboratories (621511)

SIC

Services-Commercial Physical & Biological Research (8731), In Vitro & In Vivo Diagnostic Substances (2835), Services-Medical Laboratories (8071)

akta.pro primary industry

Sample Collection, Stabilization & Pre-Analytics (biobanking, transport media, extraction kits) (HLAAALAM)

akta.pro secondary industries

Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays) (HLAGAIAF), Multiplex & High-Throughput Diagnostics Platforms (microarrays, digital PCR, lab automation-enabled assays) (HLAAALAL), Sample / Biorepository & Biobank Informatics (Chain-of-Custody) (HLAGAJAH)

Keywords

• Biospecimen products
• Nucleic acid extraction
• Spatial biology services
• FFPE tissue samples
• Molecular biology reagents

Headquarters

HQ city

Newark

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Supply Chain, Personnel, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Biospecimen Sales: Sale of human biospecimens including FFPE tissue, frozen tissue, DNA, RNA, protein, and matched pair samples (tumor and adjacent normal) for research applications. Products sold via catalog and custom procurement.
2. Automated Instruments: Sale of AnaPrep 12 Dx and AnaPrep 48 automated nucleic acid extraction instruments, priced at $34,300 for the AnaPrep 48 instrument. Consumables and reagents for these instruments are sold separately as recurring revenue.
3. Extraction and Purification Kits: Sale of xTractPure extraction kits for DNA, RNA, and protein from various sample types. Includes AnaPrep reagent kits sold in pack sizes (e.g., 48 extractions). Kit prices range from $380 to $880 depending on the kit type.
4. Custom Services: Fee-for-service including spatial multiomics services (10x Visium, Xenium, NanoString GeoMx), biospecimen procurement, custom extraction and purification, histology services, targeted gene expression profiling, and OEM manufacturing (ISO 9001:2015 certified).
5. Reference and Control Standards: Sale of reference tissues, reference DNA/RNA/protein, characterized tissues, FDA arrays, HCR verified tissues, and plasma reference materials for use as controls in molecular diagnostic and research assays.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels7 records

Core offering

BioChain supplies human biospecimens (FFPE and frozen tissue, DNA, RNA, protein, matched pair samples), automated nucleic acid extraction instruments (AnaPrep 12 Dx and AnaPrep 48), magnetic bead-based extraction kits (xTractPure), reference and control standards (FDA-approved tissue arrays, characterized tissues), and fee-for-service spatial multiomics and histology services to pharmaceutical, biotechnology, academic, and government research customers.

Differentiator

Problem solved

Functional benefit

Products and services

• Human Biospecimens (FFPE Tissue, Frozen Tissue, DNA, RNA, Protein, Matched Pair Samples) Catalogue of high-quality, characterized human biospecimens including FFPE and frozen tissue sections, isolated DNA, RNA, and protein, and matched tumor/normal paired samples, sourced under ISO and IRB approved procurement for genomics, NGS, qPCR, and spatial biology research.
• AnaPrep Automated Sample Preparation Systems (AnaPrep 12 Dx and AnaPrep 48) Benchtop automated nucleic acid extraction instruments using magnetic bead technology with pre-programmed protocols; the AnaPrep 48 processes up to 48 samples and is positioned as an open system compatible with third-party magnetic bead kits, while the AnaPrep 12 Dx adds traceability for clinical diagnostic use.
• xTractPure Extraction and Purification Kits Magnetic bead-based extraction kits for DNA, RNA, and protein from diverse sample types, including dedicated FFPE DNA, FFPE DR (combined RNA/DNA), biofluid DNA, blood RNA, cell and tissue nucleic acid, and viral nucleic acid kits, suitable for use on the AnaPrep 48 and other open magnetic bead systems.
• Liquid Biopsy Solutions (cfPure cell-free nucleic acid kits and mutational quantification control plasma) Cell-free nucleic acid extraction kits (cfPure) and matched mutational quantification control plasma reference materials used in liquid biopsy workflows such as cell-free DNA isolation and downstream molecular analysis.
• Reference and Control Standards (FDA-approved tissue arrays, characterized tissues, HCR verified tissue, reference DNA/RNA/protein, plasma) Reference tissues, reference DNA/RNA/protein, plasma reference materials, FDA-approved tissue arrays, NGS- and 10x Visium-characterized tissues, and HCR verified tissues used as controls and benchmarks in molecular diagnostic and research assays, including clinical trial and diagnostic test development.
• Spatial Multiomics Services (10x Visium HD, 10x Xenium Prime 5K, NanoString GeoMx DSP) End-to-end fee-for-service spatial biology offerings combining client tissue samples with 10x Visium HD whole-transcriptome analysis at 2µm resolution, 10x Xenium Prime 5K single-cell imaging of up to 5,000 genes, and NanoString GeoMx DSP multiplexed protein/RNA profiling, delivered by BioChain as a certified service provider.
• Custom Histology Services (tissue sectioning, microarray construction, whole slide imaging, FFPE cell line blocks) Custom histology services covering tissue sectioning and tissue microarray construction, whole slide imaging, and preparation of FFPE cell line and cell culture blocks for research and assay development customers.
• OEM and Custom Manufacturing Services (ISO 9001:2015) ISO 9001:2015 certified OEM and custom manufacturing services for bulk reagent supply, custom extraction and purification, biospecimen procurement, and targeted gene expression profiling for partner manufacturers and research customers.

Quantifiable outcome

• 10x Genomics and NanoString certified spatial biology services for whole transcriptome and targeted spatial profiling
• +3 more outcomes

Named customers8 records

Segments3 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

Feature8 records

Partnerships

Three partnerships are on record, tiered core.

• Ambergen, Inc.coreStrategic or Co-development Partner · 24 February 2026BioChain co-hosts a joint webinar with Ambergen, Inc. titled 'Unlocking the Full Potential of Biospecimens for Multiomic and Spatial Analyses' scheduled for February 24, 2026. The collaboration brings together BioChain's biospecimen expertise with Ambergen's bioinformatics and spatial multiomic imaging capabilities. Featured presenters include Nisshanthini Durairaju (BioChain), Leonardo Garcia Dettori (Ambergen), and John Gillespie, President and CEO of Ambergen. The webinar focuses on integrated workflows combining proteomic, lipidomic, and transcriptomic imaging for multiomic research applications.
• 10x GenomicscoreTechnology or IntegrationBioChain is a certified provider for 10x Genomics spatial biology platforms, offering 10x Visium HD and 10x Xenium Prime 5K characterized tissues and spatial multiomics services. BioChain provides pre-validated, spatially characterized human tissue sections compatible with 10x Genomics Visium HD and Xenium workflows, enabling whole transcriptome and targeted gene expression spatial profiling.
• NanoString TechnologiescoreTechnology or IntegrationBioChain is NanoString certified, offering NanoString GeoMx DSP characterized tissues and spatial profiling services. The partnership enables customers to access NanoString's digital spatial profiling technology with BioChain's characterized tissue products for multiplexed protein and RNA analysis in tissue sections.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Charles River Laboratories: Charles River provides research models, biospecimens, discovery, and safety assessment services to pharma and biotech. Its Research Models & Services and biospecimen supply overlap with BioChain's IRB-approved biospecimen procurement and custom lab services for translational and clinical research.
• Abcam: Abcam is a leading research-reagent company specializing in antibodies and protein research tools, serving pharma, biotech, and academic markets globally. It is comparable to BioChain as a catalog reagent and reference-materials provider, though with a primary focus on antibodies rather than biospecimens and spatial workflows.
• MilliporeSigma (Merck KGaA Life Science): MilliporeSigma is the life-science arm of Merck KGaA, offering a vast portfolio of reagents, kits, instruments, and reference standards used in molecular biology, genomics, and bioprocessing. It competes with BioChain across extraction kits, sample prep consumables, and reference materials, with a much larger global scale and instrument footprint.
• Bio-Techne: Bio-Techne is a large, diversified life-science tools provider offering proteins, antibodies, reagents, and biospecimens across research and diagnostics. It is comparable to BioChain as a competing supplier of research-grade reagents and biospecimens to pharma/biotech and academic customers, though with a far broader and more clinical-diagnostic-anchored portfolio.

Emerging players

• Proteintech Group: Proteintech is a rapidly growing antibody and protein reagent manufacturer serving academic and pharma researchers worldwide. It is comparable to BioChain as a catalog reagent supplier targeting publication-driven researchers, though with a narrower focus on antibodies and proteins rather than biospecimens and spatial workflows.
• Akoya Biosciences: Akoya is a spatial biology specialist offering the PhenoCycler and PhenoImager platforms for multiplex tissue imaging. It overlaps with BioChain's spatial multiomics service offering as a competing spatial technology platform with which BioChain could partner or against which it positions its 10x/NanoString certified services.

Direct peers

• OriGene Technologies: OriGene is a direct competitor supplying cDNA clones, antibodies, FFPE and frozen tissue arrays, RNA/DNA extracts, and molecular biology reagents to academic and pharma researchers. Its catalog overlaps closely with BioChain's biospecimens, extraction kits, and reference standards for spatial and molecular applications.
• Cell Signaling Technology: Cell Signaling Technology (CST) is a research-reagent specialist producing antibodies, ELISA kits, and validation-grade protein tools for signaling pathway and biomarker research. It overlaps with BioChain's reference protein and antibody-adjacent reagent offerings and similarly serves pharma R&D and academic customers seeking publication-grade data.
• Discovery Life Sciences: Discovery Life Sciences is a biospecimen procurement and analytical services provider offering human tissue, biofluids, and custom lab services to translational and clinical research customers. It is one of the closest direct peers to BioChain's core biospecimen and custom extraction/purification business, with comparable IRB-governed sourcing and pharma/academic customer base.

Regional players

• AMS Biotechnology (AMSBIO): AMSBIO is a UK-based supplier of life-science research reagents, biospecimens, primary cells, and molecular biology kits primarily serving European and APAC academic/biotech markets. It is comparable to BioChain as a competing catalog biospecimen and reagent provider, though operating through a different geographic footprint and distributor-led channel.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/biochain-institute-inc
• Xx.com/biochain
• Facebookfacebook.com/biochain

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Biochain