What Biosearch Technologies does

Biosearch Technologies designs, develops, and manufactures custom oligonucleotide-based tools and nucleic acid chemistry products serving molecular diagnostics, agrigenomics, nucleic acid therapeutics, and research institutions. Its core technology centers on solid-phase oligonucleotide synthesis with controlled pore glass (CPG) platforms, phosphoramidite chemistry, and over 1,000 modifications across 9+ probe types including BHQ quenchers, LNA, MGB, and molecular beacons. The portfolio spans custom DNA/RNA probes and primers, nucleic acid purification kits (sbeadex, Quickextract, Mag, MasterPure), PCR/qPCR reagents and master mixes (RapiDxFire), high-throughput genotyping platforms (SNPline, Array Tape, KASP chemistry), Stellaris RNA FISH technology, MerMade oligonucleotide synthesizers, therapeutic delivery modifiers (GalNAc for liver targeting, lipophilic modifications for extrahepatic delivery), and molecular biology enzymes.

The business operates a hybrid go-to-market combining self-service e-commerce (biosearchtech.com and oligos.biosearchtech.com) for catalog and SMB research customers with direct enterprise sales teams supporting OEM and kit manufacturing, cGMP-grade custom synthesis for IVD and therapeutic applications, and contract laboratory services (genotyping, sequencing, nucleic acid extraction). Distribution spans five geographies (United Kingdom headquarters, United States, Germany, Singapore, China) with regional sales contacts and an authorized distributor network. The company operates cGMP manufacturing with ISO certifications and holds 80+ patents supporting its nucleic acid chemistry and synthesis capabilities.

Biosearch Technologies is a division and brand within LGC Group, a privately-held diversified science company, with legal entity LGC Genomics Limited. The company is not publicly traded, has no disclosed venture or growth capital backing, and competes in custom oligonucleotide synthesis and molecular diagnostics inputs alongside firms such as Agilent, IDT (Danaher), and Nitto Denko Avecia. Ronald Cook is identified as founder, president, and CEO.

Name

Biosearch Technologies

Legal name

LGC Genomics Limited

Website

https://biosearchtech.com

Company type

Private

Founded year

1980

Operating status

Operating

Headcount range

51–100 employees

Short description

Biosearch Technologies, a division of LGC Group, designs and manufactures custom oligonucleotides, nucleic acid chemistry reagents, and high-throughput genotyping platforms serving molecular diagnostics, agrigenomics, and nucleic acid therapeutics companies globally.

Ownership category

akta.pro rank

Headquarters

HQ city

Petaluma

HQ country

United States

HQ region

North America

Offices5 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Supply Chain, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Custom Oligonucleotide and Probe Sales: Sale of custom oligonucleotides including DNA probes, primers, and modified oligos with various modifications (fluorescent labels, quenchers, lipophilic conjugates, GalNAc, etc.) sold in tubes, plates, or bulk quantities through e-commerce platform.
2. Nucleic Acid Chemistry Reagents: Sale of phosphoramidites, CPG supports, nucleosides, modified synthesis reagents, synthesis instruments and accessories for oligo synthesis.
3. Molecular Biology Enzymes and Kits: Sale of enzymes including polymerases, nucleases, ligases, RNase inhibitors, competent cells, and complete kits for PCR, qPCR, isothermal amplification, in vitro transcription, and other molecular biology applications.
4. OEM and Kit Manufacturing Services: Custom manufacturing services for molecular diagnostics companies requiring GMP-grade oligos and kit components for commercial IVD products.
5. Genotyping and Sequencing Services: Laboratory services including KASP genotyping, targeted sequencing (Amp-Seq, Flex-Seq), microbial sequencing, metagenomics, and bioinformatics analysis for agrigenomics and clinical research applications.
6. Nucleic Acid Extraction Services: DNA and RNA extraction services from various sample types including animal, plant, and clinical samples with quality analysis and management.

Pricing tiers

Go-to-market motion2 records

Distribution channels6 records

Marketing channels8 records

Core offering

Biosearch Technologies designs, develops, and manufactures custom oligonucleotide-based tools, nucleic acid chemistry reagents, PCR/qPCR reagents and consumables, and high-throughput genotyping instrumentation. It also delivers contract laboratory services including KASP genotyping, targeted and microbial sequencing, nucleic acid extraction, and OEM/kit manufacturing for molecular diagnostics and therapeutic customers. Operations span cGMP manufacturing with proprietary phosphoramidite chemistry, controlled pore glass (CPG) supports, and more than 1,000 oligo modifications.

Product overview

Biosearch Technologies, operating under LGC Group, offers an end-to-end portfolio of genomics products and services spanning nucleic acid chemistry, sample preparation, PCR-based detection, oligonucleotide synthesis, next-generation sequencing, and genotyping. The core product lines include: (1) Nucleic Acid Sample Preparation reagents and instruments including oKtopure automated DNA extraction systems and sbeadex purification kits; (2) PCR Instruments, Reagents and Consumables including RapiDxFire master mixes, custom DNA probes (BHQ, LNA, MGB types), and SNPline/Array Tape high-throughput platforms; (3) Nucleic Acid Chemistry Reagents including PrimeMax siRNA CPG, GalNAc modifiers for liver targeting, lipophilic modifiers (cholesterol, palmitate) for cell delivery, Locked Nucleic Acids (LNA), Peptide Nucleic Acids (PNA), fluorophores/quenchers, and MerMade oligonucleotide synthesizers; (4) Molecular Biology Enzymes including nucleases, polymerases, and transcription kits; (5) KASP Genotyping platform for SNP analysis; (6) Stellaris RNA FISH platform for RNA localization; (7) NGS products including Amp-Seq One kits and sequencing services; and (8) Contract services for genotyping, sequencing, and OEM kit manufacturing. The company operates under cGMP standards with ISO certifications supporting diagnostics and therapeutic development.

Differentiator

Problem solved

Functional benefit

Brands

• Stellaris: RNA FISH platform for RNA fluorescence in situ hybridization probe sets and buffers
• KASP
• sbeadex
• PrimeMax
• MerMade
• BHQ Probes
• SNPline

Products and services

• KASP Genotyping Assays Complete PCR-based SNP genotyping platform including KASP-TF Master Mix, pre-validated SNP assays, on-demand assay design, and genotyping services for agricultural and clinical applications.
• Stellaris RNA FISH RNA fluorescence in situ hybridization platform including Shipready Control Probe Sets, Designready Professionally Designed Probe Sets, Custom RNA FISH Probe Sets, and Stellaris RNA FISH Buffers for intracellular RNA localization.
• MerMade Oligonucleotide Synthesizers Family of DNA/RNA oligonucleotide synthesizers (MerMade 4, MerMade 48X, MerMade 192X) for automated oligo synthesis at research, mid-throughput, and high-throughput GMP production scales.
• SNPline Plate-Based Genotyping Platform Automated plate-based genotyping instrument platform including Kube Automated Thermal Plate Sealer, Fusion3 1536-Well Microplate Sealer, Hydrocycler Thermal Cycler, and supporting barcode readers.
• Array Tape Ultra-High-Throughput Platform Ultra-high-throughput PCR platform using array tape technology including Soellex Thermal Cycler, Araya Assay Detection, Intelliqube Automated PCR Instrument, and Nexar Inline Liquid Handling System.
• sbeadex Nucleic Acid Purification Kits Magnetic bead-based DNA and RNA purification kits (including sbeadex Lightning with a 5-minute protocol) for rapid, high-quality extraction from plant, animal, and clinical samples.
• oKtopure Bead-Based Automated DNA Extraction System Automated bead-based DNA extraction system for high-throughput nucleic acid purification from various sample types.
• Custom DNA Probes for qPCR Custom-synthesized DNA probes including Scorpions Primers, Locked Nucleic Acid Probes, BHQ Probes, BHQplus Probes, BHQnova Probes, Molecular Beacon Probes, and Minor Groove Binder (MGB) Probes for qPCR assay developers.
• RapiDxFire PCR and qPCR Master Mixes Ready-to-use PCR/qPCR master mixes for gene expression analysis, lyophilized one-step RT-qPCR, BHQ-probe qPCR, and KASP genotyping applications.
• Quickextract DNA and RNA Extraction Chemistry Rapid DNA and RNA extraction chemistry for quick purification of nucleic acids from biological samples.
• PrimeMax siRNA CPG Optimized controlled pore glass (CPG) platform for high-performance siRNA synthesis with improved pore size, surface area normalized loading (SANL), and enhanced purity and stability.
• GalNAc and Lipophilic Delivery Modifiers N-Acetylgalactosamine (GalNAc) and lipophilic modifications including cholesterol, palmitate, stearate, and tocopherol for targeted delivery of therapeutic oligonucleotides to liver hepatocytes and extrahepatic tissues (CNS, eye, lung).
• Locked Nucleic Acids (LNA) and Peptide Nucleic Acids (PNA) Backbone-modified nucleotides (LNA, PNA) that increase melting temperature, hybridization affinity, and nuclease resistance for qPCR probes and antisense applications.
• Genotyping Services Contract laboratory services including KASP genotyping, genotyping by sequencing (GBS), targeted genotyping sequencing, whole genome amplification, and marker-assisted selection (MAS) support.
• Sequencing Services Comprehensive sequencing services including Amp-Seq One targeted genotyping by sequencing, metagenomics sequencing, microbial whole genome sequencing (WGS), and bioinformatic analysis.
• Nucleic Acid Extraction Services DNA and RNA extraction services for sample processing and purification from animal, plant, and clinical samples, with quality analysis.
• OEM and Kit Manufacturing Services Custom original equipment manufacturing and kit assembly services for molecular diagnostics companies requiring GMP-grade oligonucleotides and kit components for commercial IVD and therapeutic products.
• Amp-Seq One Targeted Genotyping by Sequencing Kits Targeted genotyping kits using amplicon sequencing technology for plants and livestock genetic analysis, sold as complete kits.
• PCR Forge Assay Design Software Online design tool for PCR, qPCR, and genotyping assay probe and primer design supporting batch and multiplex design modes.
• KASP-TF Master Mix Competitive allele-specific PCR master mix formulated for KASP SNP genotyping assays.
• Valupanel PCR Assays for Pathogen Detection Pre-configured PCR assay panels for detection of pathogens across various sample types, sold as ready-to-use panels.
• Fluorophores and Quenchers Fluorescent dyes and quenchers including CAL Fluor, Cyanine, Dabsyl, Dabcyl, DDQ, Fluorescein, ROX, TAMRA, BBQ, BHQ, and BlueBerry for custom probe labeling.

Quantifiable outcome

• 40+ years of experience supporting global healthcare diagnostics
• +2 more outcomes

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature9 records

Scale indicators5 records

Recent moves5 records

Expansion highlights6 records

Direct peers

• Integrated DNA Technologies (IDT): IDT is the most direct competitor to Biosearch Technologies in custom oligonucleotide synthesis, offering DNA/RNA oligos, modifications, qPCR probes, and gene synthesis. Acquired by Danaher in 2018, IDT competes head-to-head across research, diagnostic, and therapeutic oligo use cases.
• Eurofins Genomics: Eurofins Genomics provides custom oligo synthesis, genotyping services, sequencing, and nucleic acid extraction, overlapping directly with Biosearch's core catalog and services portfolio across research and agrigenomics customers.

Emerging players

• Synthego: Synthego is an emerging player in synthetic biology focused on CRISPR reagents and high-throughput oligonucleotide synthesis, competing with Biosearch in synthetic RNA oligos and gene editing research tools for therapeutic customers.
• Twist Bioscience: Twist Bioscience competes with Biosearch in synthetic DNA and oligo manufacturing using a silicon-based DNA writing platform, with overlap in gene fragments, oligo pools, and NGS-related reagents.
• GenScript: GenScript is a global CDMO and oligo/peptide supplier with significant overlap to Biosearch in custom oligos, gene synthesis, and protein/oligonucleotide manufacturing services for research and therapeutic customers.

Broad incumbents

• Thermo Fisher Scientific: Thermo Fisher offers custom oligos (via the former Life Technologies portfolio), qPCR reagents, and nucleic acid extraction products that overlap with Biosearch's catalog, but as part of a much broader life sciences portfolio rather than as a specialist.
• Bio-Rad Laboratories: Bio-Rad competes in qPCR reagents, digital PCR, and life science research tools with overlap against Biosearch's PCR enzyme, master mix, and probe offerings, especially in clinical diagnostics-adjacent workflows.
• Qiagen: Qiagen competes in nucleic acid extraction (e.g., QIAamp-style kits), PCR/qPCR reagents, and OEM genomics components, overlapping with Biosearch's sbeadex extraction kits and OEM/kit manufacturing services.
• Agilent Technologies: Agilent competes with Biosearch in oligonucleotide therapeutics manufacturing (via its Resolution Bioscience and nucleic acid solutions businesses), particularly for GMP-grade therapeutic oligo CDMO services.

Others

• LGC Group (parent context): LGC Group is the parent conglomerate of Biosearch Technologies; relevant as the strategic owner and for benchmarking how Biosearch's portfolio compares to LGC's other genomics and diagnostics holdings (SeraCare, Rapid Genomics, Lucigen).

Market position

Strengths5 records

Weaknesses5 records

Competitive moat3 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/biosearchtech
• YouTubeyoutube.com/channel/UCxq8Kk3h4K4JxT8eW5lKL4w
• Facebookfacebook.com/BiosearchTechnologies
• LinkedInlinkedin.com/company/biosearch-technologies
• Instagraminstagram.com/biosearchtech

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Biosearch Technologies