Dent Neurologic Institute

What Dent Neurologic Institute does

Dent Neurologic Institute is the largest outpatient neurology practice in the United States, founded in 1963 and headquartered in Amherst, New York. The organization operates 26 neurology subspecialty clinics across four Western New York locations (Amherst, Buffalo/Wehrle, Orchard Park, Batavia), staffed by over 100 providers serving approximately 330,000 patients annually. Its clinical portfolio spans MS, movement disorders, stroke, epilepsy, headache, concussion, sleep, neuromuscular, neuro-oncology, behavioral health, neuropsychology, memory disorders, pediatric neurology, and medical cannabis, supported by an in-house imaging center, infusion center, sleep lab, and over 100 ongoing clinical research trials.

The practice generates revenue primarily through fee-for-service clinical neurology care (patient visits, procedures, infusions, diagnostics billed to insurance and patients) and secondarily through research contracts, grants, and pharmaceutical sponsor relationships for its clinical trial portfolio. The go-to-market is sales-led via physician referrals and direct appointments, augmented by an online scheduling platform powered by Luma Health's Operational AI. Operational technology includes Hyperfine's Swoop portable MRI system, validated at 92% diagnostic agreement with conventional MRI in the NEURO PMR study. The institute maintains institutional partnerships with Roswell Park Cancer Institute, SUNY Buffalo School of Medicine (training and faculty pipeline), the Muscular Dystrophy Association, and the Alzheimer's Association. The practice is privately held and physician-owned, led by Dr. Laszlo L. Mechtler (Medical Director) and Dr. Vernice E. Bates (President), with no disclosed venture capital or private equity ownership.

Name

Dent Neurologic Institute

Legal name

Dent Neurologic Institute

Website

https://dentinstitute.com

Company type

Private

Founded year

1963

Operating status

Operating

Headcount range

251–500 employees

Short description

Dent Neurologic Institute is the largest outpatient neurology practice in the United States, operating 26 subspecialty clinics across four Western New York locations. With over 100 providers, it serves 330,000+ patients annually across all major neurology subspecialties.

Ownership category

akta.pro rank

Headquarters

HQ city

Amherst

HQ country

United States

HQ region

North America

Offices4 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Clinical Neurology Services: DENT generates revenue through providing outpatient neurology clinical services across 26 subspecialty centers, treating approximately 330,000 patients annually. Revenue is derived from patient visits, procedures, infusions, and diagnostic services billed through insurance and patient payments.
2. Clinical Research Trials: DENT operates over 100 ongoing clinical research trials, generating revenue through research contracts, grants, and pharmaceutical company partnerships for drug trials and clinical studies.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

Dent Neurologic Institute is a private outpatient neurology practice founded in 1963 that operates 26 sub-specialty clinics staffed by more than 100 providers across four locations in Western New York. The institute treats over 330,000 patients annually and runs more than 100 active clinical research trials, delivering neurology subspecialty care, advanced neuroimaging, infusion therapy, sleep medicine, and neuropsychology services.

Product overview

Dent Neurologic Institute is the largest outpatient neurology practice in the United States, founded in 1963, offering a comprehensive suite of neurological care services across 26 subspecialty clinics. The institute provides core clinical services including neurology consultations, advanced neuroimaging (MRI, CT, angiography), award-winning infusion therapies, and neuropsychological evaluations. The practice operates an extensive clinical research program with over 100 ongoing trials and maintains specialized centers for sleep disorders, behavioral health, concussion, medical cannabis, and various neurological conditions including multiple sclerosis, movement disorders, epilepsy, and stroke. Patient access is facilitated through Luma Health's scheduling platform, with multiple locations in Western New York.

Differentiator

Problem solved

Functional benefit

Products and services

• Outpatient neurology subspecialty clinics
• Clinical research trials program

Quantifiable outcome

• Treats nearly 1,300 patients per day, amounting to over 330,000 patients annually
• +1 more outcomes

Named customers1 record

Segments3 records

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature1 record

Partnerships

Seven partnerships are on record, tiered core and strategic.

• Luma HealthcoreTechnology or Integration · 18 February 2026DENT implemented Luma Health's Operational AI platform across their health system workflows. The platform has been deployed for patient access, engagement, intake, and payment capture. At DENT, the Conversational Agent reduced call abandonment by more than one-third and cut average call answer times by 75 percent. The system handles care-related next steps and staff scheduling optimization.
• HyperfinecoreTechnology or IntegrationDENT deployed Hyperfine's Swoop portable MRI system at their outpatient neurology practice. The portable MRI demonstrated 92% diagnostic agreement with conventional MRI in the NEURO PMR study involving 125 patients. Patients strongly preferred the portable system, being four times more likely to choose it over conventional scans due to greater comfort and reduced anxiety.
• CannformaticsstrategicStrategic or Co-development PartnerCannformatics and Dr. Laszlo Mechtler of DENT announced intent to launch a joint venture for developing a saliva-based lab testing platform for personalized medical cannabis treatment for migraine and neurological disorders. The research will involve 150 migraine patients and is expected to begin in the second half of 2026 after IRB approval.
• Roswell Park Cancer InstitutecoreStrategic or Co-development PartnerDr. Laszlo Mechtler serves as Chief of Neuro-Oncology at Roswell Park Cancer Institute while also serving as Medical Director of DENT Neurologic Institute. This partnership enables integrated neuro-oncology care combining DENT's neurology expertise with Roswell Park's cancer treatment capabilities.
• State University of New York at Buffalo (SUNY Buffalo)strategicStrategic or Co-development PartnerMultiple DENT physicians serve as faculty at SUNY at Buffalo School of Medicine. Dr. Mechtler is Professor of Neurology and Neuro-Oncology at SUNY Buffalo. Dr. Bates is Associate Clinical Professor of Neurology. DENT residents train through SUNY Buffalo programs, creating a pipeline of neurologists.
• Muscular Dystrophy Association (MDA)coreStrategic or Co-development PartnerDENT hosts MDA Clinic at both Amherst and Orchard Park locations, providing multidisciplinary care for neuromuscular disorder patients. The MDA Clinic rotates through the full spectrum of services during patient visits, addressing the specific needs of patients with muscular dystrophy and related conditions.
• Alzheimer's AssociationstrategicStrategic or Co-development PartnerDENT works closely with the Alzheimer's Association, hosting Memory Disorders Support Group meetings and collaborating on patient care. The institute's Integrative Center for Memory provides comprehensive dementia care in partnership with Alzheimer's Association resources.

Scale indicators5 records

Recent moves6 records

Expansion highlights4 records

Broad incumbents

• Cleveland Clinic Neurological Institute: Major academic health system's neurology service line covering the full subspecialty spectrum including research and trials. Comparable subspecialty coverage but operates within a hospital system rather than independent outpatient model.
• Mount Sinai Neurology: Academic neurology program within a large NYC health system offering subspecialty care, research, and clinical trials. Comparable breadth but hospital-system delivery model.
• Mayo Clinic Department of Neurology: National academic neurology department with full subspecialty coverage and large clinical trial portfolio. Comparable research and subspecialty depth but inpatient-integrated rather than independent outpatient.

Direct peers

• Pacific Neuroscience Institute: Outpatient-focused neuroscience specialty group on the West Coast providing neurology and neurosurgery subspecialty care with research programs. Comparable as a multi-subspecialty independent outpatient neurology practice.
• Noran Neurological Clinic: Independent outpatient neurology group practice in Minnesota offering multispecialty neurology services including MRI, infusion, and EMG. Most directly comparable independent outpatient neurology peer by structure and service mix.
• Northwest Neurology (Chicago): Independent neurology group practice serving the Chicago metro with subspecialty neurologists and in-office imaging. Direct structural peer as a large independent outpatient neurology group.
• Indiana Neuroscience Associates: Independent outpatient neurology practice in Indianapolis offering comprehensive neurological services across multiple subspecialties with imaging capabilities. Comparable independent group structure and service breadth.

Regional players

• Mischer Neuroscience Institute (Memorial Hermann): Houston-based neuroscience service line within a major health system providing comprehensive neurological and neurosurgical care. Comparable subspecialty model but hospital-integrated and regional.
• Marcus Neuroscience Institute: Hospital-affiliated neuroscience institute in Florida offering subspecialty neurology and neurosurgery with research programs. Comparable subspecialty breadth and clinical trial activity in a different region.

Others

• Hyperfine: Portable MRI device maker whose Swoop system is deployed at DENT. Adjacent as a technology partner and ecosystem participant in portable neuroimaging, not a competitor.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xtwitter.com/dentinstitute
• YouTubeyoutube.com/user/dentneurology
• Facebookfacebook.com/dentinstitute
• Instagraminstagram.com/dentinstitute
• LinkedInlinkedin.com/company/dent-neurologic-institute

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Dent Neurologic Institute