What Alkaloid AD Skopje does

Alkaloid AD Skopje is a North Macedonian pharmaceutical and consumer-products manufacturer founded in 1936, operating through four business segments anchored by Pharmaceuticals (91% of FY2024 consolidated sales) and Chemicals, Cosmetics and Botanicals (9%). The Pharmaceuticals segment produces prescription drugs, OTC medicines, medical devices, and food supplements across solid oral, cephalosporin, liquid, semi-solid, and sterile dosage forms, while Botanicals covers teas, food products, and food supplements (GOOD NATURE, GRINI, Zachinal), Cosmetics covers skincare, hair care, perfumes, and household cleaners (including the BECUTAN baby-care brand), and Chemistry covers pure chemicals, reagents, agricultural products, and disinfectants. The company serves healthcare providers, wholesale distributors, retail pharmacy chains, and end consumers in more than 50 countries.

Manufacturing is anchored by GMP-certified facilities in Skopje, validated under European, WHO, MHRA (Great Britain), and US FDA standards, alongside ISO 9001/14001/13485/45001, FSSC 22000, HACCP, HALAL, organic (EU/USDA-NOP/JAS), and CE-for-medical-devices certifications. The internal technology stack centers on AlkaSAP, a proprietary SAP S/4HANA ERP with FI/CO/MM/WM/SD/PP/QM/HR modules, supplemented by AlkaDMS (document management), AlkaCDS (chromatography data system), and AlkaT&T (track and trace), all GAMP-validated. In March 2026, ANT Solutions integrated its MES/EBR platform into Alkaloid's production operations to further automate batch records and compliance.

The business model combines direct sales through 22 wholly-owned subsidiaries and 2 representative offices across SEE, Western Europe, Eastern Europe, CIS, the UK, and the USA, contract manufacturing for approximately 30 multinational pharmaceutical companies, and consumer-goods distribution through retail chains including Lidl in France, Latvia, and Lithuania. In FY2024, Alkaloid generated MKD 19,005,696,029 in consolidated sales (15% growth), MKD 1,684,020,094 in net profit (7% growth), and ended the year with a market capitalization of MKD 40,435,722,250 on the Macedonian Stock Exchange (ticker ALK) with over 6,532 shareholders.

Name

Alkaloid AD Skopje

Legal name

Alkaloid AD Skopje

Website

https://alkaloid.com.mk

Company type

Public

Founded year

1936

Operating status

Operating

Headcount range

1,001–5,000 employees

Short description

Alkaloid AD Skopje is a North Macedonian pharmaceutical and consumer-products manufacturer founded in 1936, producing prescription drugs, OTC medicines, cosmetics, botanicals, and chemicals. It serves healthcare providers, wholesalers, retailers, and consumers across 50+ countries through 22 subsidiaries and contract manufacturing for 30+ multinational companies.

Ownership category

akta.pro rank

Product category

Pharmaceutical manufacturing

NAICS

Pharmaceutical Preparation Manufacturing (325412), Drugs and Druggists' Sundries Merchant Wholesalers (424210), Medicinal and Botanical Manufacturing (325411)

SIC

Pharmaceutical Preparations (2834), Wholesale-Drugs, Proprietaries & Druggists' Sundries (5122), Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Generic Hospital & Institutional Products (HLAIABAL)

akta.pro secondary industries

OTC & Consumer Health Distributors (HLAIAJAC), Pharmacy Front-End & Sundries Distribution (Health & Wellness, Personal Care, Convenience) (CRAOAHAG)

Keywords

• Pharmaceutical manufacturing
• Generic medicines
• Cosmetics production
• Botanical products
• Contract manufacturing

Headquarters

HQ city

Skopje

Offices7 records

Markets served

GTM type

B2B and B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Pharmaceuticals: Manufacturing and sale of pharmaceutical products including prescription medicines, OTC products, medical devices, and food supplements. Accounts for 91% of total consolidated sales. Exports to 50+ countries worldwide.
2. Chemicals, Cosmetics and Botanicals: Production and sale of chemicals (pure chemicals, reagents, agricultural products), cosmetics (skin care, hair care, perfumes, household cleaners), and botanical products (teas, food products, food supplements). Accounts for 9% of total consolidated sales.

Go-to-market motion2 records

Distribution channels4 records

Marketing channels6 records

Core offering

Alkaloid AD Skopje manufactures and sells a diversified portfolio of pharmaceutical products (prescription medicines, OTC, medical devices, food supplements), botanical products (teas, food, food supplements), cosmetics (skin care, hair care, perfumes, Becutan baby care, household products), and chemicals (pure chemicals, reagents, disinfectants, agricultural products). The Pharmaceuticals segment accounts for 91% of consolidated sales; products are distributed in 50+ countries through wholly owned subsidiaries, its own wholesale arm (Alkaloid KONS), and contract manufacturing partnerships with multinational pharma companies.

Product overview

Alkaloid AD Skopje operates as a diversified pharmaceutical and consumer goods company with four main business segments: Pharmaceuticals (manufacturing drugs, OTC medicines, medical devices, and food supplements), Botanicals (teas, food products, and food supplements under brands like GOOD NATURE, GRINI, and Zachinal), Cosmetics (skin care, hair care, perfumes, and household products including the Becutan brand), and Chemistry (pure chemicals, reagents, and disinfectants). The company operates internal technology systems including AlkaSAP (SAP S/4 HANA ERP platform), AlkaDMS (Document Management System), AlkaCDS (Chromatography Data System), and AlkaT&T (Track & Trace), and serves healthcare professionals through the Alkaloid ProNet portal providing accredited content and tools. Alkaloid exports to over 50 countries worldwide.

Differentiator

Problem solved

Functional benefit

Brands

• ALKA-LAB: Laboratory services subsidiary in Slovenia
• ALKA-LAB D.O.O. Ljubljana
• AlkaSAP
• AlkaDMS
• AlkaCDS
• AlkaT&T
• AlkaSpeakUp
• Alkaloid ProNet
• GOOD NATURE
• GOOD NATURE ENERGY
• GRINI
• Zachinal
• BECUTAN

Products and services

• Pharmaceuticals segment Manufacturing of drugs, OTC medicines, medical devices, and food supplements across solid oral dosage forms, cephalosporin dosage forms, liquid dosage forms, and semi-solid and sterile dosage forms; sold to hospitals, pharmacies, wholesalers, and as contract manufacturing for multinational pharma companies. Represents 91% of consolidated sales.
• Botanicals segment Processing of botanical raw materials and production of teas, food products, food supplements, and borderline products under organic and conventional methods, including sub-brands GOOD NATURE (teas and healthy food), GOOD NATURE ENERGY, GRINI (spices and dried vegetables), and Zachinal (food supplements).
• Cosmetics segment
• Chemistry segment
• Contract manufacturing for multinational pharmaceutical companies Toll / contract manufacturing of pharmaceutical products for approximately 30 well-known multinational companies, leveraging GMP-certified production facilities in Skopje, FDA-inspected Botanicals Program, and validated ERP and track-and-trace systems.
• Alkaloid ProNet — Healthcare Professional Portal Specialized digital platform targeting healthcare professionals (doctors, pharmacists) with accredited lectures, therapeutic area information, diagnostic tools, guidelines, event information, and webinars for continuing medical education.

Quantifiable outcome

• 15% revenue growth in 2024 reaching MKD 19 billion
• +3 more outcomes

Named customers2 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

One partnership is on record.

• ANT SolutionscoreTechnology or Integration · 25 March 2026ANT Solutions integrated its MES/EBR (Manufacturing Execution System/Electronic Batch Records) system with Alkaloid's pharmaceutical manufacturing operations in North Macedonia, enabling improved production tracking, compliance documentation, and manufacturing process automation.

Scale indicators14 records

Recent moves7 records

Expansion highlights5 records

Direct peers

• Hemofarm AD (STADA Group): Serbian pharmaceutical manufacturer within STADA, focused on generics and OTC across SEE and CEE. Strongly comparable geographically and in product categories.
• KRKA, d. d., Novo Mesto: Slovenian pharmaceutical manufacturer with a generics-led portfolio, vertically integrated subsidiaries, and strong presence across CEE/Western Europe. Highly comparable to Alkaloid in product mix, export orientation, and own-distribution model.
• Gedeon Richter Plc. Hungarian-based branded and generic pharmaceutical group with deep CEE roots and growing Western European footprint. Closely comparable in regional manufacturing presence, generics focus, and export-led business model.
• Zentiva Group: European generics manufacturer headquartered in Prague with broad branded-generic portfolio across CEE/EU markets. Comparable generics-led model, vertical distribution, and cross-border manufacturing footprint.
• Bosnalijek d.d. Sarajevo: Bosnian pharmaceutical manufacturer producing generics, OTC, and consumer health products for regional and export markets. Highly comparable in scale, regional positioning, and product mix.
• Egis Pharmaceuticals PLC: Hungarian-based pharmaceutical manufacturer (within Servier group) producing generics, OTC, and APIs for CEE and global markets. Comparable in GMP-certified manufacturing, generics focus, and regional export orientation.
• Polpharma S.A. Polish pharmaceutical manufacturer of generics, OTC, and APIs with strong CEE presence and growing EU exports. Comparable generics manufacturing scale and regional distribution strategy.

Broad incumbents

• STADA Arzneimittel AG: German-based broad generics and consumer-health group active across CEE/EU markets through subsidiaries including Hemofarm. Overlaps with Alkaloid's product categories but operates at materially larger scale across wider geographies.
• Sandoz International GmbH: Global generics-focused business carved out of Novartis, supplying pharmaceuticals and biosimilars globally. Competes with Alkaloid in generics but at vastly greater scale and broader portfolio.
• Teva Pharmaceutical Industries Ltd. Israel-based global generics and specialty pharma leader. Competes broadly with Alkaloid in generics and OTC categories; useful as a scale reference point and category benchmark.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/user/AlkaloidSkopje
• Facebookfacebook.com/AlkaloidSkopje
• LinkedInlinkedin.com/company/alkaloid-ad
• Instagraminstagram.com/alkaloidskopje

Compliance25 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Subsidiaries7 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments1 record

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Alkaloid AD Skopje