Phileo by Lesaffre

What Phileo by Lesaffre does

Phileo by Lesaffre is the animal nutrition and health division of Lesaffre, a global fermentation and microbial solutions group. Headquartered in Marcq-en-Baroeul, France, the company develops and sells yeast- and bacteria-based probiotics, yeast fractions, selenized yeast, and animal-free chondroitin sulfate for livestock, poultry, swine, aquaculture, horses, and companion animals. Core technologies include proprietary Saccharomyces cerevisiae strains (Actisaf, Procreatin 7), the patented GO Technology enabling Bacillus spore germination within 4-6 hours, three patented Bacillus strains (NRRL B-67647/48/49) used in Microsaf, and the CNCM I-3399 strain underlying Selsaf 3000.

The portfolio spans 12+ branded SKUs, including Actisaf (live yeast probiotics for ruminants, poultry, swine), Safmannan and Safglucan (purified yeast fractions for gut health and immunity), Safwall (mycotoxin adsorption), Prosaf and Nucleosaf (yeast extracts), Selsaf 3000 (selenized yeast at 3,000 ppm), Microsaf (multi-species Bacillus probiotic), and Safchondro (animal-free chondroitin for joint health). Service offerings include Feed Tech Service, which analyzes 2,000+ feed samples annually for pelleting-condition validation, and Digescan for feed diagnostics.

Phileo operates 16 production plants across five continents and serves customers in over 70 countries through a direct enterprise sales motion supplemented by regional distributors. Its revenue model is product sales to feed manufacturers and farmers with quote-based pricing and technical service engagements; no specific pricing or contract terms are publicly disclosed. The company is a subsidiary of privately held Lesaffre, with no independent funding history, and pursues an R&D-intensive product strategy targeting antibiotic reduction, heat stress management, sustainable protein, and gut health outcomes.

Name

Phileo by Lesaffre

Legal name

Phileo by Lesaffre

Website

https://phileo-lesaffre.com

Company type

Private

Operating status

Operating

Headcount range

101–250 employees

Short description

Phileo by Lesaffre is the animal nutrition division of Lesaffre, developing patented yeast and Bacillus probiotics, yeast fractions, and selenized yeast for livestock, poultry, swine, aquaculture, and companion animal feed manufacturers and farmers globally.

Ownership category

akta.pro rank

Product category

Animal Feed Additives

NAICS

Other Animal Food Manufacturing (311119)

SIC

Food And Kindred Products (2000), Agricultural Prod-Livestock & Animal Specialties (200)

akta.pro primary industry

Probiotics, Prebiotics & Postbiotics (Direct-Fed Microbials) (AFADALAE)

akta.pro secondary industries

Yeast Products & Fermentation Metabolites (Yeast Culture, MOS/β-Glucans) (AFADALAM), Immune & Stress Modulators (Beta-glucans, Nucleotides) (AFADAKAH)

Keywords

• Yeast probiotics
• Animal feed additives
• Livestock gut health
• Yeast fractions
• Microbial feed ingredients

Headquarters

HQ city

Marcq-en-baroeul

HQ country

France

HQ region

Europe

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales

Revenue model

1. Probiotic and Yeast Product Sales: Sale of yeast probiotics (Actisaf), yeast fractions (Safmannan, Safglucan, Safwall), selenized yeast (Selsaf), bacterial probiotics (Microsaf), and related animal nutrition products to feed manufacturers and farms.
2. Technical Services: Feed Tech Service providing feed analysis, technical support, and consulting to feed manufacturers on probiotic integration into pelleted feeds.

Pricing tiers

Go-to-market motion3 records

Distribution channels3 records

Marketing channels6 records

Core offering

Phileo by Lesaffre develops, manufactures, and sells yeast- and bacteria-based probiotic and functional ingredient products (probiotic yeasts, selenized yeast, yeast cell wall fractions, multi-strain Bacillus probiotics, and animal-free chondroitin) used as feed additives for ruminants, poultry, swine, aquaculture, horses, and pets. The company also provides technical feed analysis services (Feed Tech Service and Digescan) to help feed manufacturers optimize probiotic stability in pelleted feeds.

Product overview

Phileo by Lesaffre is a provider of yeast probiotics and microbial solutions for animal nutrition and health. The product portfolio centers on Saccharomyces cerevisiae-based yeast probiotics (Actisaf Sc 47, Actisaf Sc 48, Actisaf Sc 50 PET, Procreatin 7) as the core offerings, supplemented by functional yeast fractions including Safmannan (mannan-oligosaccharides and betaglucans), Safglucan (purified betaglucans for immunity), Safwall (mycotoxin adsorption), Prosaf (protein-rich yeast extract), and Nucleosaf (nucleotide-rich extract). The company also offers selenized yeast (Selsaf 3000), a bacterial probiotic (Microsaf with GO Technology), and companion animal joint health products (Safchondro PET and Equine). Services include Feed Tech Service for feed manufacturers and Digescan for diagnostic analysis. Products address species including dairy, beef, poultry, swine, aquaculture, horses, pets, insects, layers, turkeys, and small ruminants.

Differentiator

Problem solved

Functional benefit

Brands

• Actisaf: Yeast probiotic product line for animal nutrition
• Safmannan
• Microsaf
• Selsaf 3000
• Safglucan
• Safwall
• Prosaf
• Nucleosaf
• Procreatin 7
• Safchondro
• Feed Tech Service
• Digescan Service

Products and services

• Actisaf Sc 47 Reference yeast probiotic (Saccharomyces cerevisiae) for ruminants and livestock, designed to improve rumen and intestinal health, feed efficiency, and animal performance.
• Actisaf Sc 48 Inst+ formulation of the Actisaf yeast probiotic for specific applications in animal nutrition.
• Actisaf Sc 50 PET Patented probiotic solution specifically formulated for companion animals (dogs and cats) targeting gut health and microbiome support.
• Microsaf Next-generation multi-species bacterial probiotic utilizing GO Technology (Germination Optimisation Technology) with three Bacillus strains for poultry gut health, feed efficiency, and pathogen control.
• Procreatin 7 Patented Saccharomyces cerevisiae probiotic yeast strain with 22 years of use history, designed to optimize dairy cattle digestion, control acidosis, and improve milk fat yield.
• Prosaf Highly purified, soluble yeast extract with over 63% protein content, essential amino acids, glutamic acid, nucleic acids, and B vitamins for improving feed palatability, digestibility, and growth performance in aquaculture and swine.
• Nucleosaf Premium yeast extract rich in free nucleotides to support rapid animal growth, intestinal development, and zootechnical performance in young animals during weaning stress.
• Safglucan Purified yeast fraction concentrated with minimum 50% 1.3/1.6 betaglucans extracted from Saccharomyces cerevisiae, designed to enhance innate immunity and trained immunity in animals and improve vaccination response.
• Safmannan Premium selected yeast fraction rich in mannan-oligosaccharides and betaglucans (1.3 and 1.6), for pathogen reduction, gut health, and immune modulation in poultry, fish, and pets.
• Safwall Selected yeast cell wall fraction from Saccharomyces cerevisiae for mycotoxin adsorption, reducing bioavailability of ZEA and OTA and protecting intestinal barrier integrity in livestock and poultry.
• Selsaf 3000 Selenized yeast from specific CNCM I-3399 yeast strain providing organic selenium with 3000 ppm concentration, containing selenocysteine and selenomethionine, for oxidative stress management and immune function.
• Safchondro PET Sustainable, animal-free chondroitin sulfate solution designed to support joint health in dogs and companion animals.
• Safchondro Equine Sustainable, animal-free chondroitin sulfate solution designed to support joint health in horses.
• Feed Tech Service Comprehensive service for feed manufacturers analyzing over 2,000 feed samples annually to assess multifactorial resistance of Actisaf yeast probiotic under pelleting conditions, delivered through a digital platform.
• Digescan Service Diagnostic service for feed analysis and animal gut health assessment.

Quantifiable outcome

• Dairy farms: Feed represents 50-70% of variable costs; yeast probiotics optimize feed efficiency and reduce costs
• +3 more outcomes

Named customers6 records

Segments6 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature8 records

Partnerships

Eight partnerships are on record, tiered core and minor.

• CanBiocincoreStrategic or Co-development Partner · 11 July 2025Partnership to expand presence in worldwide companion animal care market. Phileo and CanBiocin announced collaboration following positive EFSA opinion for Microsaf, combining their expertise in probiotic solutions for companion animals.
• Feed Manufacturers and Industry Experts NetworkcoreStrategic or Co-development PartnerPhileo R&D teams work together with a network of industry experts to provide Feed Tech Service to customers, developing the digital platform for feed analysis.
• Texas A&M University (Gastrointestinal Laboratory)minorStrategic or Co-development PartnerDr. Jan Suchodolski serves as keynote speaker at Biotics 2024 Symposium. Texas A&M GI Lab conducts microbiome research relevant to companion animal health.
• University of Illinois Urbana-ChampaignminorStrategic or Co-development PartnerDr. Kelly Swanson serves as keynote speaker at Biotics 2024 Symposium. University conducts nutrition research including pet food studies.
• Federal University of Paraná, BrazilminorStrategic or Co-development PartnerDr. Ananda Portella Félix serves as keynote speaker at Biotics 2024. Coordinates research laboratory on dog nutrition.
• Iowa State UniversityminorStrategic or Co-development PartnerDr. Elizabeth Bobeck serves as keynote speaker at Biotics 2024 Symposium on companion animal nutrition.
• University of Lisbon (CIISA)minorStrategic or Co-development PartnerDr. Manuela Oliveira serves as keynote speaker at Biotics 2024. Center for Interdisciplinary Research in Animal Health conducts relevant research.
• American Society of Animal Science (ASAS)coreGTM or Marketing PartnerPhileo by Lesaffre hosts Biotics 2024 Companion Animal Health Symposium at ASAS-CSAS-WSASAS annual conference July 21-25, 2024 in Calgary, Canada. Company sponsors companion animal mixer.

Scale indicators5 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Lallemand Animal Nutrition: Lallemand is the most direct yeast probiotic peer to Phileo, offering Levucell SB (S. cerevisiae) and bacterial probiotics for ruminants, swine, poultry and aquaculture with global field sales. Strong technology and species overlap make it Phileo's closest benchmark.
• Alltech: Alltech is a global yeast-based animal nutrition company anchored by Yea-Sacc, Bioplex, and Sel-Plex selenized yeast, directly competing with Phileo's Actisaf and Selsaf 3000 across species and geographies.
• Novonesis (formerly Chr. Hansen) Animal Health: Novonesis's animal health division sells Bacillus probiotic strains (e.g., GalliPro, BioPlus) for poultry and swine, directly competitive with Phileo's Microsaf multi-species Bacillus offering using GO Technology.
• Biorigin: Biorigin, a Zilor subsidiary, is a Brazilian yeast-derived feed additive maker with products like BionatYeast and MacroGard beta-glucans, directly competing with Phileo's Safmannan and Safglucan in gut health and immunity.
• Kemin Industries: Kemin offers a broad specialty feed additive portfolio including probiotics and immune modulators for poultry and swine, overlapping with Phileo's Microsaf and Safglucan across the same large feed manufacturer customer base.
• AB Vista: AB Vista, part of Associated British Foods, supplies specialty feed ingredients including yeast-based products and gut health additives, mirroring Phileo's sell-through to feed manufacturers in multiple species.

Broad incumbents

• dsm-firmenich Animal Nutrition & Health: dsm-firmenich's ANH division offers a broad portfolio of vitamins, eubiotics, and feed additives including VevoVitall and probiotic blends; overlaps with Phileo via ruminant and poultry gut health solutions.
• ADM Animal Nutrition: ADM Animal Nutrition operates globally in feed ingredients and premixes with biotech additives; comparable buyer base to Phileo but at much broader scale and a wider feed additive portfolio.
• Cargill Animal Nutrition: Cargill provides a broad feed additive, premix and complete feed offering including Diamond V and proprietary gut health products, addressing the same feed manufacturer and large livestock integrator customers as Phileo.
• Elanco Animal Health: Elanco is a global animal health company with feed additive and nutritional health offerings; large incumbent footprint overlaps with Phileo especially in poultry and swine, though Elanco's primary focus is pharmaceuticals rather than yeast probiotics.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/PhileoLesaffre
• YouTubevimeo.com/phileo
• Facebookfacebook.com/phileo.lesaffre
• LinkedInlinkedin.com/company/phileo

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Phileo by Lesaffre