Imaging Endpoints

What Imaging Endpoints does

Imaging Endpoints is a privately-held imaging contract research organization (iCRO) that designs, executes, and analyzes medical imaging for pharmaceutical and biotechnology-sponsored clinical trials, with an exclusive focus on oncology. The company customizes imaging acquisition protocols and analysis criteria (RECIST 1.1, iRECIST, PCWG3, Choi, Lugano, RANO) for each trial, then operates a cloud-based, globally distributed infrastructure spanning 35+ countries and seven offices (Scottsdale HQ, Cambridge, Leiden, Basel, North Harrow, Hyderabad, Shanghai) to deliver real-time reads by credentialed radiologists. Its research arm (Deep Imaging, Tumor Microenvironment, Theragnostic Development, Imaging Biomarkers, 3D Virtual Reconstruction, Big iData) layers radiomics, AI/ML, and quantitative textural analysis (TexRAD) onto standard-of-care imaging to extract additional efficacy signals and to support regulatory submissions.

Name

Imaging Endpoints

Legal name

Imaging Endpoints II LLC

Website

https://imagingendpoints.com

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

101–250 employees

Short description

Imaging Endpoints is the largest oncology-focused imaging CRO (iCRO), providing customized imaging protocol design, centralized radiologist reads, and AI/radiomics-enabled analysis for pharmaceutical and biotech-sponsored oncology clinical trials across 35+ countries.

Ownership category

akta.pro rank

Product category

Clinical Trial Imaging Services

NAICS

Scientific Research and Development Services (5417), Software Publishers (513210)

SIC

Services-Health Services (8000)

akta.pro primary industry

Imaging Core Labs & Clinical Endpoint Adjudication (HLAGAEAH)

akta.pro secondary industries

AI Orchestration & Imaging Analytics Platforms (Model Management/Triage) (HLACALAG), Medical Imaging AI (HDAAAEAH), Imaging Informatics & Workflow (PACS/RIS/VNA) (HLAHABAI)

Keywords

• Clinical trial imaging
• Imaging core lab
• Oncology imaging services
• Radiomics analysis
• Medical imaging CRO

Headquarters

HQ city

Scottsdale

HQ country

United States

HQ region

North America

Offices7 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Clinical Trial Imaging Services: Imaging Endpoints provides comprehensive imaging CRO services for clinical trials, specializing in oncology imaging analysis. The company develops and deploys optimal imaging in early-stage trials, advances imaging analysis into late-stage trials, and supports regulatory submissions. Revenue is generated through service contracts with pharmaceutical and biotech companies conducting clinical trials.

Go-to-market motion2 records

Distribution channels1 record

Marketing channels5 records

Core offering

Imaging Endpoints is the largest oncology-focused imaging contract research organization (iCRO) globally. It develops and deploys optimal imaging strategies for early-stage oncology clinical trials, advances imaging analysis into late-stage trials, and supports regulatory submissions for pharmaceutical and biotechnology sponsors. The company delivers centralized imaging review, radiomics analysis, AI/ML-enabled biomarker discovery, and cloud-based infrastructure across more than 35 countries.

Product overview

Imaging Endpoints is the largest oncology-focused imaging CRO (iCRO) offering a comprehensive platform of clinical trial imaging services. The core offering includes Imaging Endpoints Services encompassing Oncology Imaging Services, Rescue Studies, and IT Infrastructure. The platform is enhanced by Research Endpoints services including Deep Imaging, Tumor Microenvironment Analysis, Theragnostic Development, Imaging Biomarkers, 3D Virtual Reconstruction, and Big iData Searchable Databases. The company leverages advanced technologies including radiomics, artificial intelligence, and cloud-based infrastructure to support clinical trials across all phases, operating in over 35 countries with real-time image receipt, query management, and reads for rapid clinical trial decisions.

Differentiator

Problem solved

Functional benefit

Brands

• Clinical Endpoints: Clinical endpoints services brand operated by Imaging Endpoints
• Revolution Endpoints
• Caring Endpoints

Products and services

• Imaging Endpoints Services (Core iCRO Services) World-class scientific expertise and imaging services backed by an industry-leading quality management system for clinical trials across all phases of oncology drug development.
• Oncology Imaging Services Specialized imaging services for oncology clinical trials including customized criteria, radiomics, and artificial intelligence to optimize drug development across multiple cancer types including prostate, breast, lung, hematologic malignancies, and rare diseases.
• Deep Imaging (Research Endpoints) Advanced imaging technologies including additional acquisition sequences, parameters, tumor microenvironment analysis, and advanced post-processing technologies such as Tumor Growth Kinetics and Radiomics with AI.
• Theragnostic Development Research service supporting theranostic and radioligand therapy trials, quantifying whole-body tumor burden, bone marrow involvement, and minimal residual disease using PET and SPECT imaging.
• Imaging Biomarkers Development and validation of imaging biomarkers for clinical trials, including quantitative metrics from radiomic analysis linking imaging with omics enhanced by AI.
• 3D Virtual Reconstruction Advanced imaging visualization service providing three-dimensional reconstructions for enhanced clinical trial analysis.
• Big iData Searchable Databases Comprehensive searchable database of imaging data for research and analysis purposes, supporting big data analysis and radiomics research.

Quantifiable outcome

• 95% marketing authorization success rate
• +3 more outcomes

Named customers4 records

Segments2 records

Ideal customer profiles1 record

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability11 records

Feature7 records

Partnerships

Three partnerships are on record, tiered core.

• HonorHealthcoreOthersImaging Endpoints is an affiliate of HonorHealth, one of the largest healthcare systems in the USA. HonorHealth is home to the Virginia G. Piper Cancer Center. This affiliation provides strategic access to clinical expertise and healthcare infrastructure.
• Southwest Medical Imaging, Ltd. (SMIL/RadPartners)coreOthersImaging Endpoints is an affiliate of Southwest Medical Imaging, Ltd. (SMIL/RadPartners), ranked as the largest private radiology group in the USA. This partnership provides access to extensive radiology expertise and infrastructure.
• Scientific Advisory Board MemberscoreStrategic or Co-development PartnerImaging Endpoints has a Scientific Advisory Board including world-class radiologist Elliot K. Fishman from Johns Hopkins Hospital to help guide imaging efforts. The board provides expert guidance on imaging science and clinical trial strategies.

Scale indicators7 records

Recent moves9 records

Expansion highlights4 records

Broad incumbents

• IQVIA: IQVIA is the world's largest CRO with broad imaging capabilities embedded in its clinical operations offering. As a broad incumbent, it competes with IE on large, multi-modality oncology trials where sponsors prefer a single-vendor solution, though its imaging expertise is less specialized than IE's.
• ICON plc: ICON is a top-tier global CRO with an imaging core lab offering acquired through its PRDO and other transactions. As a broad incumbent, it competes with IE on integrated imaging-plus-operations trial delivery for large pharma sponsors.
• Medpace: Medpace is a mid-to-large global CRO with growing imaging capabilities serving oncology and other therapeutic areas. It is a broad incumbent competing with IE for oncology trial work, particularly with mid-sized biotech sponsors.
• Parexel: Parexel is a large global CRO with imaging and biomarker services for clinical trials. As a broad incumbent, it offers sponsors integrated clinical operations plus imaging, putting competitive pressure on specialty imaging CROs like IE.

Direct peers

• WorldCare Clinical (WCG): WorldCare Clinical (now part of WCG) is an imaging CRO providing independent image review and centralized imaging services for clinical trials, with a particular focus on oncology and ophthalmology. It directly competes with IE for pharma-sponsored imaging work.
• Clario (formerly ERT/Bioclinica): Clario (formed from the merger of ERT and Bioclinica) is a leading imaging core lab and eCOA/eClinical provider serving clinical trials globally. It is the most direct competitor to Imaging Endpoints in oncology imaging core lab services, with comparable offerings in centralized imaging review, radiomics, and multi-modality oncology trial support.
• Invicro: Invicro is a specialized imaging CRO providing PET, MRI, and radiomics services for clinical trials, with deep expertise in neuroimaging and oncology. It directly competes with IE on imaging core lab services, AI-enabled image analysis, and biomarker development for pharma/biotech sponsors.
• Calyx (formerly BioClinica/Molecular Imaging): Calyx (formerly the Molecular Imaging business of BioClinica) provides medical imaging management and AI-enabled image analysis for clinical trials, with a strong oncology and neuroscience focus. It is a direct peer in imaging CRO services for pharma and biotech sponsors.
• Pharmtrace: Pharmtrace is a specialized imaging CRO focused on CNS and oncology clinical trials, providing centralized imaging review and advanced image analysis. It is a direct peer in the imaging core lab niche that competes with IE for biomarker-driven oncology imaging work.

Emerging players

• Bayer Radiology / Median Technologies: Median Technologies is an emerging imaging CRO/AI vendor providing iCRO and imaging AI services for oncology clinical trials. It competes with IE for sponsor work in AI-driven oncology imaging analysis, with a particular focus on iBiopsy and iCRO offerings.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xtwitter.com/ImagingEndpoint
• Facebookfacebook.com/ImagingEndpointsII
• LinkedInlinkedin.com/company/1448054
• Instagraminstagram.com/imaging_endpoints

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Imaging Endpoints