ZRT Laboratory

What ZRT Laboratory does

ZRT Laboratory is a CLIA-certified diagnostic laboratory founded in 1998 by breast cancer researcher Dr. David Zava, headquartered in Beaverton, Oregon. The company specializes in hormone, neurotransmitter, heavy metal, and wellness biomarker testing using four proprietary sample-collection modalities: saliva (pioneered by ZRT in 1998), dried blood spot (first commercialized by ZRT for hormone therapy monitoring), dried urine (methodology developed by ZRT), and serum. Its technical differentiation rests on a proprietary saliva extraction process that separates hormones from background contamination, age-, menstrual status-, and supplementation-adjusted reference ranges, and exclusive qualification in the CDC's Hormone Standardization Program (HoSt) — the only specialty hormone laboratory to pass both the CDC Testosterone and Estradiol Reference Methods. Over 10 million cumulative tests have been completed with a 3–5 business day turnaround, serving providers in all 50 US states and 96 countries plus research institutions including the CDC, NIH, and major universities.

ZRT's product portfolio spans Female/Male Saliva Profiles (I, II, III), Comprehensive Male Profile II, Cardiometabolic Health, Thyroid, Heavy Metals & Essential Elements, Neurotransmitters, Vitamin D, Menstrual Cycle Mapping, Sleep Balance, and the newly launched AMH fertility profile, delivered via four sample types through the myZRT provider/patient portal. The business is a hybrid provider-channel / direct-to-consumer model: licensed healthcare practitioners order kits through dedicated provider accounts (the primary revenue channel), while patients in Direct Access Testing states can order directly via store.zrtlab.com. Revenue comes from per-test diagnostic fees, out-of-network insurance billing (Medicare Part B, Medicare Advantage, TRICARE, Humana, and select plans), and discounted direct-patient prepayment; pricing is not publicly disclosed and is accessed through the provider portal. Distribution is supported by a multi-channel marketing engine — content marketing, webinars, social media, provider education resources, the Find a Provider locator, and industry-conference lectures by the in-house clinical consultant team (three NDs with 12–17 years of tenure) — driving demand across the integrated and conventional medicine provider ecosystem.

Name

ZRT Laboratory

Legal name

ZRT Laboratory, LLC

Website

https://zrtlab.com

Company type

Private

Founded year

1998

Operating status

Operating

Headcount range

51–100 employees

Short description

ZRT Laboratory is a CLIA-certified specialty diagnostic lab that provides at-home saliva, dried blood spot, dried urine, and serum testing for hormones, neurotransmitters, heavy metals, and wellness biomarkers, serving healthcare providers across 50 US states and 96 countries plus individual patients and research institutions.

Ownership category

akta.pro rank

Product category

Clinical Diagnostic Laboratory Services

NAICS

Medical and Diagnostic Laboratories (62151), Medical Laboratories (621511)

SIC

Services-Medical Laboratories (8071)

akta.pro industry

PRIMARYHLAFAMAJ

Reference & Esoteric Testing Laboratories

Healthcare & Life Sciences/Healthcare Providers & Systems/Clinical Laboratories

Keywords

• Hormone testing
• Saliva diagnostics
• Dried blood spot
• Dried urine testing
• Clinical lab services

Headquarters

HQ city

Beaverton

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure, Supply Chain

Revenue model

1. Diagnostic Testing Services: ZRT Laboratory generates revenue primarily through diagnostic laboratory testing fees charged to healthcare providers and patients for its range of hormone, neurotransmitter, heavy metals, thyroid, and cardiometabolic tests. Test kits are ordered online via store.zrtlab.com or through provider accounts, and results are delivered via the myZRT portal. Pricing is accessible through the provider portal (myZRT.com) and is not publicly listed on the consumer website.
2. Insurance Billing (Out-of-Network): ZRT courtesy bills select insurance plans as an out-of-network provider, including Original Medicare Part B, Medicare Advantage Plans, TRICARE, and Humana. Most insurance companies do not cover testing unless a medical professional has provided a written prescription.
3. Direct Patient Prepayment: Patients can prepay for testing at a discounted price and request an itemized receipt for insurance reimbursement submission.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels7 records

Core offering

ZRT Laboratory is a CLIA-certified specialty diagnostic laboratory that provides hormone and wellness testing services using proprietary dried-sample collection methods (saliva, dried blood spot, dried urine, and serum). Tests are ordered by licensed healthcare providers via the myZRT portal or directly by patients in DAT states through store.zrtlab.com, with results delivered digitally. Offerings span hormone balance panels, cardiometabolic, thyroid, heavy metals and essential elements, neurotransmitters, fertility, and adrenal/stress testing.

Product overview

ZRT Laboratory is a CLIA-certified diagnostic laboratory offering a comprehensive portfolio of at-home hormone and wellness testing products. The company provides testing across four sample collection methods: Saliva Testing (pioneered in 1998), Blood Spot Testing, Dried Urine Testing, and Serum Testing. The core product offering includes multiple diagnostic panels including Female/Male Saliva Profiles (I, II, III), Comprehensive Male Profile II, Cardiometabolic Health Testing, Thyroid Panel, Heavy Metals & Essential Elements Testing, Neurotransmitter Testing, AMH Testing, Menstrual Cycle Mapping, and Sleep Balance Profile. These products are supported by the myZRT patient/provider portal for online report access, test kit ordering, and account management. The company serves healthcare providers in all 50 US states and 96 countries, with testing used by organizations including the CDC, NIH, and academic research institutions.

Differentiator

Problem solved

Functional benefit

Products and services

• Saliva Hormone Testing At-home saliva hormone testing measuring free bioavailable hormone levels including DHEA-S, cortisol, estradiol, estriol, estrone, progesterone, and testosterone. Pioneered by ZRT in 1998 and supported by a proprietary saliva extraction process that separates hormones from background contamination. For licensed healthcare providers and patients in Direct Access Testing states.
• Dried Blood Spot Testing Dried blood spot testing from finger-stick samples for comprehensive hormone panels, cardiometabolic markers, thyroid function, and vitamin D analysis. ZRT was first to commercialize dried blood spot testing to monitor hormone therapy accurately, with reference ranges adjusted so patients do not need to stop hormone supplementation. For healthcare providers and self-ordering patients.
• Dried Urine Hormone Testing Dried urine testing methodology developed by ZRT for measuring hormone metabolites, neurotransmitters, heavy metals, essential elements, and iodine. Provides an alternative sample type for comprehensive hormonal and toxic element assessment. For healthcare providers and self-ordering patients.
• Female/Male Saliva Profile I Basic saliva hormone panel testing estradiol, progesterone, testosterone, DHEA-S, and morning cortisol for foundational hormone balance assessment. For healthcare providers and patients in Direct Access Testing states.
• Female/Male Saliva Profile II Extended saliva panel adding evening (bedtime) cortisol to the basic profile I, recommended for patients with mild to moderate fatigue, stress, and sleep disturbance symptoms. For healthcare providers and self-ordering patients.
• Female/Male Saliva Profile III Most comprehensive saliva panel with four-point cortisol curve (morning, noon, evening, bedtime) plus full hormone panel for severe symptom assessment. For healthcare providers and self-ordering patients.
• Comprehensive Male Profile II Complete male hormone assessment including reproductive hormones, thyroid panel, adrenal hormones, and PSA measurement for prostate health monitoring. Targeted at providers treating andropause and male hormonal health.
• Cardiometabolic Health Testing Dried blood spot testing for cholesterol panel (total, HDL, LDL, VLDL), triglycerides, fasting insulin, HbA1c, high-sensitivity C-reactive protein, and insulin-like growth factor. For at-home cardiometabolic risk assessment ordered by providers or self-ordering patients.
• Thyroid Panel Dried blood spot testing for TSH, free T4, free T3, and thyroid peroxidase antibodies (TPO) for comprehensive thyroid function assessment. For providers evaluating thyroid imbalance and patients seeking at-home thyroid screening.
• Heavy Metals and Essential Elements Testing Dried urine testing for toxic heavy metals (arsenic, cadmium, lead, mercury, gadolinium) and essential elements (selenium, iodine, copper, zinc, magnesium). For providers and patients concerned with toxic exposure and nutritional status.
• Neurotransmitter Testing Dried urine testing for catecholamines (epinephrine, norepinephrine) and neurotransmitter metabolites for assessment of stress response and neurological function. For providers treating mood, anxiety, and stress-related conditions.
• AMH (Anti-Müllerian Hormone) Profile Fertility assessment test measuring Anti-Müllerian Hormone levels for ovarian reserve evaluation and PCOS diagnosis, recently added to the ZRT test menu. For reproductive endocrinologists, fertility specialists, and patients evaluating fertility status.
• Menstrual Cycle Mapping Hormone testing across multiple days of the menstrual cycle to track ovulation, progesterone production, and hormonal patterns related to fertility. For providers and patients investigating cycle irregularities, infertility, or perimenopause.
• Sleep Balance Profile Dried urine testing for melatonin and cortisol metabolites to assess sleep-wake cycles and adrenal function related to sleep disturbances. For providers and patients evaluating insomnia, shift-work fatigue, or circadian rhythm disorders.
• Vitamin D Testing Dried blood spot testing for 25-hydroxy vitamin D total levels to assess vitamin D status and deficiency. For providers and patients monitoring vitamin D supplementation or deficiency risk.
• Cortisol Awakening Response (CAR) Specialized cortisol testing measuring the 50% increase in adrenal hormones within 30 minutes of waking to assess HPA axis function and adrenal dysfunction. For providers evaluating HPA axis dysregulation, burnout, and chronic stress.
• Diurnal Cortisol Curve Four-point cortisol testing throughout the day (morning, noon, evening, bedtime) to create a circadian cortisol pattern for adrenal function assessment. For providers and patients investigating adrenal fatigue and circadian rhythm disorders.

Quantifiable outcome

• Over 10 million tests completed across healthcare providers in all 50 US states and 96 countries
• +3 more outcomes

Named customers4 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Scale indicators5 records

Recent moves5 records

Expansion highlights5 records

Broad incumbents

• BioReference Laboratories: BioReference is a full-service clinical laboratory offering routine and specialty diagnostics including endocrine panels. It serves a broad provider base and competes with ZRT in hormone testing, particularly in physician-office and specialty clinic channels.
• Sonic Healthcare USA: Sonic Healthcare is a global full-service medical laboratory operator with U.S. specialty and routine testing capabilities. As a large international lab network, it provides comparable esoteric and specialty diagnostics and competes for high-complexity testing contracts that ZRT also pursues.
• Quest Diagnostics: Quest Diagnostics is a national full-service clinical laboratory offering routine and esoteric testing including hormone panels. It is not focused on functional/integrative medicine but competes for the same patient specimens, particularly through its Cleveland HeartLab specialty offering and insurance-billed hormone tests.
• Laboratory Corporation of America (Labcorp): Labcorp is a national full-service clinical laboratory offering routine and esoteric testing, including hormone and specialty panels. It competes with ZRT for provider specimen volume and DTC consumers, with stronger in-network insurance coverage but less depth in functional medicine-specific reference ranges.

Direct peers

• Mosaic Diagnostics (formerly Great Plains Laboratory): Mosaic Diagnostics is a specialty lab serving integrative and functional medicine practitioners with hormone, neurotransmitter, heavy metals, and organic acids testing. It overlaps directly with ZRT's specialty test menu and provider base, particularly in dried-urine and blood-spot formats.
• SpectraCell Laboratories: SpectraCell is a specialty clinical laboratory offering micronutrient, cardiometabolic, and hormone testing to integrative and functional medicine providers. Its provider channel, panel-based product model, and DTC/storefront parallel ZRT's go-to-market closely.
• Genova Diagnostics: Genova Diagnostics is a specialty clinical laboratory offering dried-sample hormone, wellness, and functional medicine testing panels. It is one of ZRT's closest competitors in the integrative/functional medicine channel, serving similar providers and patients with comparable saliva, blood spot, and urine-based diagnostics.
• Doctor's Data: Doctor's Data is a specialty reference lab focused on dried-urine hormone metabolites, heavy metals, and nutritional elements — directly competing with ZRT's dried urine, heavy metals, and hormone panels within the integrative medicine provider ecosystem.

Emerging players

• Function Health: Function Health is an emerging DTC lab testing platform offering comprehensive hormone and wellness panels directly to consumers. It targets the same consumer demand for accessible hormone testing that ZRT serves in DAT states, representing a fast-growing digital-first competitor.
• Ulta Lab Tests: Ulta Lab Tests is a DTC online platform enabling consumers to order their own lab tests without a physician, including hormone panels. It competes with ZRT's DAT-state DTC channel by offering broader access and price transparency in markets where state law permits.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/zrtlab
• YouTubeyoutube.com/user/zrtlaboratory
• Facebookfacebook.com/zrtlab
• LinkedInlinkedin.com/company/zrt-laboratory
• Instagraminstagram.com/zrtlaboratory

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about ZRT Laboratory