What Custom Biogenic Systems does

Custom Biogenic Systems (CBS) designs and manufactures cryogenic storage equipment for life sciences, medical, and industrial laboratories worldwide. Founded in 1987 and headquartered in Romeo, Michigan, the company operates as a division of Standex International Corporation (NYSE: SXI) and maintains ISO 13485:2016 certification for medical device manufacturing. CBS's product portfolio centers on liquid nitrogen freezers in three families: Isothermal freezers (V Series and Carousel models) that use a patented jacketed LN2 design to deliver dry, contactless sample storage with under 10°C temperature variation top to bottom; standard cryogenic freezers (S Series) with wide-lid access; and controlled rate freezers (IntelliRate i67C and Model 2101) for programmable cryopreservation. Supporting offerings include LAB, Cryosystem XC, Cryosystem Classic, and SC Vapor Shipper dewars, configurable freezer racking, accessories (PPE, carts, hoses), and factory-trained field service with IQ/OQ qualification support.

The company sells primarily through direct quote-based enterprise sales, supplemented by a multi-distributor network and managed off-site storage repositories in the US and Europe. Pricing is largely opaque, with only a few accessory SKUs listed individually on the website (e.g., the 2101 Controlled Rate Freezer Cart at $2,076.77). Customer segments include life sciences research, medical and healthcare, oncology research, and industrial applications, with compliance to GxP, 21 CFR Part 11, and EN12830-2018 supported through the SenseAnywhere cloud monitoring integration and Kaye Validator-based qualification protocols. Go-to-market combines trade shows (Analytica 2025), educational blog content, digital advertising, email, and technical documentation. With a reported headcount of 11–50 employees and no independently disclosed financials, CBS operates as a small, specialty, IP-driven manufacturer embedded within a diversified industrial parent.

Name

Custom Biogenic Systems

Legal name

Custom Biogenic Systems

Website

https://custombiogenics.com

Company type

Private

Founded year

1987

Operating status

Operating

Headcount range

11–50 employees

Short description

Custom Biogenic Systems designs and manufactures liquid nitrogen cryogenic freezers, dewars, controlled rate freezers, and accessories for life sciences, medical, and industrial laboratories globally. The company operates as a division of Standex International Corporation and holds ISO 13485 certification.

Ownership category

akta.pro rank

Product category

Cryogenic Laboratory Equipment

NAICS

Ventilation, Heating, Air-Conditioning, and Commercial Refrigeration Equipment Manufacturing (33341), Air-Conditioning and Warm Air Heating Equipment and Commercial and Industrial Refrigeration Equipment Manufacturing (333415), Refrigerated Warehousing and Storage (49312)

SIC

Air-Cond & Warm Air Heatg Equip & Comm & Indl Refrig Equip (3585), Refrigeration & Service Industry Machinery (3580)

akta.pro primary industry

Sample Preparation, Storage & Cryogenics (Freezers, Cryovials, Cryostats) (HLAGAIAJ)

akta.pro secondary industries

Cold Chain, Cryopreservation & Biologics Storage/Handling Technologies (HLAAAJAN), Cold Chain Storage & Cryopreservation Services (LN2/Ultra-low) (HLAGAGAK), Medical & Clinical Specimen Frozen Storage (Labs, Biobanks) (TLALACAE), Dry Ice & Cryogenic (LN2) Handling and Transport Services (TLACAMAM)

Keywords

• Cryogenic storage equipment
• Liquid nitrogen freezers
• Biobanking freezers
• Cryogenic laboratory freezers
• Controlled rate freezers

Headquarters

HQ city

Romeo

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Cryogenic Freezer Sales: Sale of isothermal freezers, standard cryogenic freezers, and controlled rate freezers. Products include V Series (isothermal), S Series (standard), and controlled rate freezers with various capacity options ranging from 30L to 720L.
2. Dewars and LN2 Storage Containers: Sale of liquid nitrogen dewars including LAB Series, Cryosystems XC Series, Cryosystems Classic Series, and SC Vapor Shippers for LN2 storage and shipping.
3. Freezer Accessories: Sale of freezer racks (LN2, upright, chest), accessories including PPE, cryogenic hoses, tank switchers, sample retrieval devices, cryo-carts, and monitoring equipment.
4. Field Services and Qualification: Factory-trained service team providing preventative maintenance, calibration, IQ/OQ qualification services, temperature probe recalibration, and LN2 level sensor recalibration for CBS-manufactured cryogenic systems.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels6 records

Core offering

Custom Biogenic Systems designs and manufactures cryogenic storage equipment, including liquid nitrogen freezers (Isothermal V Series, Carousel, S Series, Controlled Rate Freezers), dewars, freezer rack solutions, accessories, and SenseAnywhere cloud monitoring. The company's flagship offering uses proprietary jacketed Isothermal LN2 technology that isolates stored biological samples from direct liquid nitrogen contact, delivering dry, uniform cryogenic storage at -196°C for life sciences, medical, and biobanking applications.

Product overview

Custom Biogenic Systems (CBS) offers a comprehensive cryogenic storage portfolio centered on liquid nitrogen freezers and related equipment. The core product lines include Isothermal Freezers (V Series wide-lid and Carousel models) featuring proprietary dry LN2 jacket technology that isolates samples from direct LN2 contact, and Standard Cryogenic Freezers (S Series) for conventional immersion storage. CBS also provides Controlled Rate Freezers (IntelliRate i67C and Model 2101) for programmable sample freezing. Supporting products include Dewars in LAB, Cryosystem XC, Cryosystem Classic, and SC Vapor Shipper series; Freezer Rack Solutions with various configurations and custom etching; SenseAnywhere cloud-based monitoring as an add-on module; Freezer Accessories including PPE, cryo-markers, carts, and hoses; and Field Services including installation qualification (IQ/OQ) protocols. The company operates under ISO 13485:2016 quality management certification.

Differentiator

Problem solved

Functional benefit

Products and services

• V Series Isothermal Freezers Jacketed liquid nitrogen freezers using proprietary dry LN2 technology where samples are isolated from direct LN2 contact, providing temperature uniformity of less than 10°C variation throughout the chamber and eliminating cross-contamination risks for laboratories and biobanks.
• Carousel Isothermal Freezers Isothermal freezers designed for facilities with ceiling height restrictions, featuring a motorized carousel and rectangular lid opening for quick rack access without moving other racks, reducing sample exposure to ambient temperatures.
• S Series LN2 Freezers Standard liquid nitrogen freezers offering conventional immersion storage with wide lid opening for unrestricted sample access, featuring vacuum-insulated stainless steel design and dual LN2 tank autofill system with 2301 controller.
• IntelliRate i67C LN2 Controlled Rate Freezer LN2 controlled rate freezer with 67-liter chamber capacity for mid-stage clinical research to commercial manufacturing volumes, capable of freezing 104 50mL bags, 1944 2mL vials, or 100 cassettes in single batches, with programmable freeze rates.
• Model 2101 Controlled Rate Freezer Controlled rate freezer with laptop controller using Windows-based operating system, temperature range of -180°C to +50°C, freeze rates of 0.01°C to 99°C per minute, six pre-set programs, and 21 CFR Part 11 compliance support.
• LAB Series Dewars Lightweight aluminum dewars with high-efficiency super-insulation available in six sizes from 4 to 50 liters, featuring up to 128 days holding time for liquid nitrogen storage and transfer.
• Cryosystem XC Series Dewars LN2 tanks with lockable hinged lids, lightweight durable construction, and five-year vacuum warranty, designed for large capacity storage with square racks and canister/cane options.
• Cryosystem Classic Series Dewars Economical cryogenic storage containers combining low LN2 consumption with mid-range vial capacity, featuring lockable lids, lightweight aluminum construction, and three-year vacuum warranty.
• SC Vapor Shipper Series Dry vapor-phase shipping containers for biological samples at -150°C or colder, enabling non-hazardous classification shipping worldwide with hydrophobic compound technology to ensure spill-free interior.
• Freezer Rack Solutions Comprehensive racking solutions including LN2 cryogenic freezer racks, upright freezer racks for ULT -80°C storage, chest freezer racks, canister/cassette systems, cane storage, and custom etching for sample management.
• SenseAnywhere Cloud Monitoring Cloud-based monitoring system connecting refrigerators, ULT freezers, and cryogenic freezers to a single account for real-time temperature tracking, alarm notifications, and compliance documentation with 21 CFR Part 11 and EN12830-2018 certification.
• Freezer Accessories Storage and freezer equipment including cryo-aprons, cryo-gloves, face shields, cryo-markers, sample retrieval devices, cryo-carts, LN2 hoses, tank switchers, and carts with roller bases.
• Field Services and Qualification Factory-trained technician services including preventative maintenance, temperature and LN2 sensor recalibration, multi-point mechanical/electrical inspections, and IQ/OQ qualification protocols for regulated environments.

Quantifiable outcome

• Temperature uniformity of less than 10°C variation from top to bottom of storage chamber
• +3 more outcomes

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration2 records

Feature6 records

Partnerships

One partnership is on record.

• SenseAnywherecoreTechnology or IntegrationSenseAnywhere provides cloud-based wireless monitoring solutions for CBS cryogenic freezers. The integration combines wireless sensors with secure cloud storage to monitor freezer performance 24/7 from anywhere, supporting 21 CFR Part 11 compliance and EN12830-2018 standards. CBS offers SenseAnywhere as an optional feature on their Isothermal freezers.

Scale indicators2 records

Recent moves6 records

Expansion highlights6 records

Emerging players

• Stirling Ultracold: Stirling Ultracold makes energy-efficient ULT mechanical freezers using Stirling engine technology; an emerging alternative to LN2 storage that could compete with CBS in environmentally-driven facilities.
• BioLife Solutions: BioLife Solutions provides cryopreservation media and biopreservation products adjacent to CBS's hardware, often co-sold in cell-and-gene therapy workflows; relevant as an ecosystem participant rather than direct freezer competitor.

Direct peers

• Cryoport Systems: Cryoport provides cryogenic cold-chain logistics and biostorage services, competing with CBS's SC Vapor Shipper line and US/Europe off-site biobanking repositories for high-value biologic shipments and storage.
• B Medical Systems: B Medical Systems manufactures medical-grade refrigerated, ULT, and plasma storage equipment used in blood banks and biobanking, overlapping with CBS's medical and healthcare customer segment.
• Worthington Industries (Life Sciences / Cryoscience): Worthington's Life Sciences / cryoscience business produces LN2 freezers and dewars for biomedical storage, directly overlapping with CBS's core cryogenic storage portfolio in research and clinical segments.
• MVE (Chart Industries): MVE, now part of Chart Industries, is one of the most established manufacturers of LN2 cryogenic freezers and vapor shippers for biobanking and life sciences - directly competing with CBS's V-Series, S-Series, and SC Vapor Shipper product lines.
• Taylor-Wharton: Taylor-Wharton manufactures a broad line of LN2 cryogenic storage tanks, controlled-rate freezers, and dewars for life sciences, fertility, and biobanking customers - the closest direct competitor to CBS across both storage and controlled-rate freezing.
• Helmer Scientific: Helmer Scientific manufactures medical-grade cold storage including ultra-low temperature and plasma freezers; relevant peer for CBS's clinical, hospital, and biobanking customers seeking temperature-controlled storage.

Broad incumbents

• Thermo Fisher Scientific: Thermo Fisher is the broadest incumbent in life sciences equipment and consumables, with cryogenic/ULT storage offerings that compete indirectly through bundling into larger lab and biobanking deals.
• Eppendorf: Eppendorf is a diversified laboratory equipment and consumables supplier whose CryoCube ULT freezers and broader lab workflow position overlap with CBS's research-laboratory target customers.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/custom.biogenics
• LinkedInlinkedin.com/company/custom-biogenic-systems-inc

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Custom Biogenic Systems