What PEPID does

PEPID (PEPID, LLC) is a privately held clinical decision support and medical reference software company founded in 1994 by Dr. Mark Rosenbloom and headquartered in Evanston, Illinois. The company provides healthcare professionals — including emergency physicians, nurses, pharmacists, nurse practitioners, EMTs/paramedics, medical students, and residents — with point-of-care access to a curated clinical content platform comprising the PEPID Knowledgebase (PKB) drug database (13,000+ drug names covering U.S. and Canadian trade names, generics, OTCs, herbals, and supplements, cross-referenced against 100,000+ drug products and 900+ nutraceuticals), 3,000+ dosing and IV-drip calculators, 800+ medical calculators/scores, a 200+ entry lab manual, 750+ procedural videos, 1,800+ medical illustrations, 1,200+ radiographic images, a differential diagnosis generator, pill identifier, and IV compatibility checker. PEPID's content is peer-reviewed by an advisory board of 35+ board-certified physicians and pharmacologists and is produced in partnership with U.S. medical societies including ASHP, ACEP, AAEM, NAEMSE, NACNS, ONS, FPIN, and BEEM, with approximately 44% of content refreshed each calendar quarter.

The platform is delivered through three distribution channels: direct subscriptions via the PEPID Connect web portal, native iOS and Android mobile apps, and the Backbone by PEPID API layer for embedding drug interaction, IV compatibility, and clinical content into third-party EMR, EHR, HIS, HIE, and patient portal systems. Revenue is generated through individual professional subscriptions priced in the $100–$300 annual range (1-/2-/3-year tiers), lower-priced student and resident monthly tiers ($8–$25/month), add-on modules such as Patient Medication Education, Bedside Education, and PEPID CME, and undisclosed institutional volume licensing plus OEM/API licensing economics. The company markets primarily via a product-led growth motion (2-week free trials across all suites) supplemented by institutional sales outreach and society-driven brand endorsement, and reports reach across thousands of institutions in 159 countries. Leadership consists of founder-CEO Dr. Mark Rosenbloom, who also serves as Editorial Director, and CTO Edward Reynolds; the company has no disclosed external funding rounds and operates with an 11–50 person headcount.

Name

PEPID

Legal name

PEPID, LLC

Website

https://pepid.com

Company type

Private

Founded year

1994

Operating status

Operating

Headcount range

11–50 employees

Short description

PEPID is a privately held clinical decision support and medical reference software company that sells specialty drug databases, calculators, and clinical content subscriptions to healthcare professionals, students, and institutions across 159 countries.

Ownership category

akta.pro rank

Product category

Clinical Decision Support Software

SIC

Services-Prepackaged Software (7372)

akta.pro primary industry

Pharmacy Information Systems (PIS) & Dispensing Workflow (HLACAKAC)

Keywords

• Clinical decision support
• Drug interaction checking
• Medical reference software
• Healthcare point-of-care
• Clinical calculators

Headquarters

HQ city

Phoenix

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Software

Cost components

Personnel, Technology or R&D

Revenue model

1. Individual Subscriptions: Subscription-based model with annual, 2-year, and 3-year billing options for individual healthcare professionals across various specialties including emergency medicine, nursing, pharmacy, and primary care.
2. Institutional Licenses: Volume-based institutional subscriptions for hospitals, health systems, and educational institutions with shared logins, IP authentication, or individual login options supporting unlimited concurrent users.
3. API/Integration Licensing: Backbone by PEPID provides drug database and clinical content integration into EMR, EHR, HIS, and other health IT systems through API licensing.

Pricing tiers

Go-to-market motion1 record

Distribution channels6 records

Marketing channels7 records

Core offering

PEPID provides web-based and mobile point-of-care clinical decision support tools and drug information resources for healthcare professionals, institutions, and students. Its portfolio includes specialty medical suites (emergency medicine, nursing, pharmacy, primary care, EMS), clinical tools such as drug interaction checkers and dosing calculators, and the Backbone API platform for integrating clinical content into EMR/EHR systems.

Product overview

PEPID offers a comprehensive clinical decision support platform comprising multiple specialized product suites for healthcare professionals across various medical specialties. The portfolio includes: EM Complete (new flagship combining adult and pediatric emergency medicine with integrated CME), Emergency Medicine Suite, Pediatric Emergency Medicine Suite, Primary Care Plus Ambulatory Care, Professional Nursing Suite, Critical Care Nursing Suite, Oncology Nursing Suite, Gerontological Nursing Suite, Clinical Rotation Companion, RN Student Clinical Companion, RN Care Plan Pro, Pharmacist Pro with AHFS, AHFS Drug Information Essentials, Portable Drug Companion, and EMS Plus NAEMSE. Supporting modules include Bedside Education, Patient Medication Education, and PEPID CME. Core tools and features include Drug Interactions Checker, IV Compatibility Checker, Dosing & Medical Calculators, Pill Identifier, Lab Manual, Medical Videos (750+), Illustrations & Radiographic Images (1,800+ illustrations, 1,200+ images), Notes & Favorites, and Differential Diagnosis Generator. Access is available via PEPID Connect (online), mobile apps (iOS/Android), and system integration through Backbone by PEPID. Founded in 1994, PEPID maintains approximately 44% content updates quarterly through an aggressive editorial cycle with peer-reviewed content from board-certified specialists.

Differentiator

Problem solved

Functional benefit

Brands

• PEPID Connect: Online clinical decision support platform accessible from any PC or Apple computer with automatic content updates
• Backbone by PEPID
• PEPID Knowledgebase (PKB)
• EM Complete
• PEPID CME

Products and services

• Emergency Medicine Suite

Quantifiable outcome

• PEPID's Drug Interactions Checker is backed by the PEPID Knowledgebase (PKB) which houses the largest drug database on the market, continuously reviewed and updated in close partnership with ASHP
• +2 more outcomes

Named customers6 records

Segments8 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration6 records

Feature8 records

Partnerships

Eight partnerships are on record, tiered core and secondary.

• American College of Emergency Physicians (ACEP)coreStrategic or Co-development PartnerACEP is a content partnership providing evidence-based essentials, guidelines, and high-resolution multimedia for PEPID's emergency medicine databases and suites.
• American Academy of Emergency Medicine (AAEM)coreStrategic or Co-development PartnerAAEM provides content partnership for emergency medicine reference materials, protocols, and evidence-based guidelines integrated into PEPID's clinical decision support suites.
• American Society of Health Systems Pharmacists (ASHP)coreStrategic or Co-development PartnerASHP partnership provides the foundation for PEPID's industry-leading drug database with continuous review and updates to ensure accuracy and comprehensiveness of drug information.
• National Association of EMS Educators (NAEMSE)coreStrategic or Co-development PartnerNAEMSE collaborated with PEPID to develop EMS Plus NAEMSE, providing complete emergency medicine reference, drug database with toxicology section, emergency protocols and evidence-based information specifically designed for pre-hospital emergency care providers.
• National Association of Clinical Nurse Specialists (NACNS)coreStrategic or Co-development PartnerNACNS partnered with PEPID to develop specialized nursing suites including Critical Care Nursing Suite (RNCC) and Gerontological Nursing Suite (RN Gero), providing evidence-based considerations and specialized content for clinical nurse specialists.
• Oncology Nursing Society (ONS)coreStrategic or Co-development PartnerONS developed PEPID Oncology Nursing Suite (RN ONS) to simplify complex cancer care and strengthen evidence-based nursing with the latest PEP cards, NANDA-I considerations, drug information, and clinical content.
• Family Physicians Inquiries Network (FPIN)secondaryStrategic or Co-development PartnerFPIN provides the latest peer-reviewed Clinical Inquiries and PURLs integrated into PEPID's Primary Care Plus and Clinical Rotation Companion suites for evidence-based clinical decision support.
• BEEM (Better Evidence and Guidelines in Emergency Medicine)secondaryStrategic or Co-development PartnerBEEM provides evidence-based essentials and guidelines integrated into PEPID's emergency medicine and pediatric emergency medicine databases.

Scale indicators8 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• UpToDate: Wolters Kluwer's evidence-based clinical decision support platform serving physicians, nurses, and healthcare professionals across specialties with similar point-of-care content and drug reference functionality.
• Medscape: WebMD's free clinical reference platform offering drug information, clinical calculators, and decision support to physicians, with overlapping user base and similar point-of-care use cases despite free/ad-supported model.
• Micromedex: Merative's drug reference and clinical decision support suite widely used by hospitals and pharmacists, providing comparable drug information, interaction checking, and IV compatibility tools to PEPID.
• Epocrates: Athenahealth's mobile-first drug reference and clinical tool for healthcare professionals, with overlapping drug interaction checking, pill identifier, and point-of-care clinical content targeted at similar clinician segments.
• Lexicomp: Wolters Kluwer's drug information and clinical decision support suite serving pharmacists and clinicians with drug interaction checking, IV compatibility, and dosing—directly overlapping PEPID Pharmacist Pro and drug database capabilities.
• DynaMed: EBSCO's evidence-based clinical reference tool competing directly with PEPID across primary care, emergency medicine, and nursing specialties with similar specialty-suite content and clinical decision support.

Emerging players

• OpenEvidence: AI-native clinical decision support platform using large language models for medical reference, representing the emerging conversational AI threat to traditional content-database CDS tools like PEPID.
• Isabel Healthcare: Differential diagnosis decision support tool that directly competes with PEPID's Differential Diagnosis Generator (DDx) functionality, focused on accelerating diagnostic accuracy for clinicians at point-of-care.
• VisualDx: Image-based clinical decision support and differential diagnosis tool with AI-augmented image recognition, competing with PEPID's DDx Generator and serving emergency medicine, dermatology, and primary care clinicians.

Broad incumbents

• ClinicalKey: Elsevier's broad clinical content platform covering drug information, clinical decision support, and evidence-based medicine across all specialties—a wider portfolio competitor with overlapping drug/clinical content but broader medical publishing footprint.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/pepid_llc
• YouTubeyoutube.com/embed/JC7S07_EQvA
• Facebookfacebook.com/pepidllc
• LinkedInlinkedin.com/company/pepid

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about PEPID