What Greenpharma does

Greenpharma S.A.S. is a French natural-product R&D solutions provider founded in December 2000 by Philippe Bernard and headquartered in Orléans. The company operates a multidisciplinary platform that combines proprietary chemoinformatics assets—the GPDB ethnopharmacological database (160,000 natural compound structures), the SELNERGY™ inverse-docking tool (10,000 annotated protein structures), and the GAINS metabolomic tool—with wet-lab capabilities spanning analytical chemistry, phytochemistry, custom synthesis, supercritical CO2 and subcritical water extraction, formulation, and medicinal chemistry. This integrated stack supports a closed-loop workflow from in silico hypothesis generation through laboratory validation and industrial scale-up, applied to the discovery and development of active ingredients.

Greenpharma commercializes ten patented cosmetic active ingredients (Algosoft, Atophylline, Centellane, Dumaflorine, Hibamorine, Hinoline, Lignarol, OCAE, Poppyderm, Primadulcine), five compound and extract libraries (GPNCL, LIGENDO, GPEL, Prestwick Chemical Library, Prestwick Phytochemical Library), and operates the Ambinter.com online procurement platform aggregating over 30 million molecule references from hundreds of vetted suppliers. The Prestwick Chemical brand and the Ambinter brand are wholly-owned commercial vehicles. Revenue is generated through FTE-based contract R&D services with dedicated PhD project managers, sales of compound libraries and active ingredients, custom synthesis and purification fees, and online catalogue transactions.

The company serves pharmaceutical, cosmetic, agrochemical, nutraceutical, and animal health industries, alongside academic and research institutions, with named customers including Nuxe, LIERAC, Phytoderm, and Merck. Long-standing R&D partnerships with the University of Strasbourg and scientific advisory relationships with Prof. Gérald Guillaumet and Prof. Jacques Haiech underpin the innovation pipeline. The company is privately held under French S.A.S. structure, employs 11–50 staff, and maintains a global footprint claim primarily through the Ambinter and Prestwick distribution channels.

Name

Greenpharma

Legal name

GREENPHARMA S.A.S.

Website

https://greenpharma.com

Company type

Private

Founded year

2000

Operating status

Operating

Headcount range

11–50 employees

Short description

Greenpharma is a French natural-product R&D solutions provider serving pharmaceutical, cosmetic, agrochemical, and nutraceutical companies with proprietary databases, inverse-docking software, patented cosmetic active ingredients, compound libraries, and FTE-based contract research services.

Ownership category

akta.pro rank

Product category

Pharmaceutical and Cosmetic R&D Services

NAICS

Medicinal and Botanical Manufacturing (325411), Scientific Research and Development Services (5417)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

AI/ML Platforms for Drug Discovery & Experiment Optimization (HLAGAJAO)

akta.pro secondary industries

Botanical & Herbal Extracts (Adaptogens, Polyphenols, Essential Oils, Standardized Extracts) (AFAJAKAD), Bio-based Pharmaceuticals, Nutraceuticals & Specialty Bioactives (EUAAAIAK)

Keywords

• Natural product research
• Cosmetic active ingredients
• Compound libraries
• Contract research services
• Phytochemistry extraction

Headquarters

HQ city

Orléans

HQ country

France

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Active Ingredients for Cosmetics: Greenpharma develops and supplies patented or proprietary active ingredient products to cosmetic brands. Ingredients include Algosoft, Atophylline, Centella asiatica extract, Dumaflorine, Hibamorine, Hinoline, Lignarol, Poppyderm, and Primadulcine. Revenue is generated through product sales of formulated ingredients to cosmetics manufacturers.
2. Compound and Extract Libraries: Sale of pre-formatted compound libraries (GPNCL, LIGENDO, GPEL) and phytochemical libraries (PCL, PPL) for biological screening in 96-well microplate format. Libraries include Greenpharma Natural Compound Library, Greenpharma Ligand Library, Extract Library, and Prestwick Chemical Libraries. Revenue is generated through one-time or recurring library sales with optional resupply.
3. Contract R&D Services: Full-service R&D under contract including active ingredient development, medicinal chemistry, formulation, phytochemistry, chemoinformatics, QSAR, virtual screening, analytical chemistry, and industrial scale-up. Services are delivered using Full Time Equivalent (FTE) schema with dedicated project managers. Clients engage for specific platform components or entire global R&D projects from concept to ingredient supply.
4. Ambinter.com Molecule Sales: Ambinter brand supplies fine chemicals, screening compounds, building blocks, fragments, and natural products through an online catalogue. Access to over 30 million references via a single procurement interface with hundreds of vetted suppliers.
5. Custom Synthesis and Purification: Custom synthesis from milligram to gram scale, as well as natural product purification on demand. Delivered using in-house chemistry expertise and analytical platform (NMR, LC/MS, HPLC, HRMS). Customers are in direct contact with a designated PhD project manager throughout the collaboration.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

Greenpharma supplies natural product-based R&D solutions, proprietary active ingredients for cosmetics, and compound libraries for drug discovery to pharmaceutical, cosmetic, and agrochemical industries. The company integrates informatic discovery tools (GPDB, SELNERGY, GAINS) with wet-lab capabilities (phytochemistry, extraction, synthesis, formulation) to deliver end-to-end services from molecule identification through industrial-scale active ingredient production.

Product overview

Greenpharma is a phytochemistry-driven R&D solutions provider offering a comprehensive portfolio of natural product-based solutions for pharmaceutical, cosmetic, and agro-food industries. The portfolio centers on three core product lines: (1) Ten proprietary Active Ingredients including Algosoft, Atophylline, Centellane, Dumaflorine, Hibamorine, Hinoline, Lignarol, OCAE, Poppyderm, and Primadulcine for cosmetics applications; (2) Five Compound Libraries (GPNCL, LIGENDO, GPEL, PCL, PPL) plus the Ambinter.com platform providing access to 30+ million molecules for drug discovery; and (3) Comprehensive R&D Services including GreenOvation strategy, QSAR, virtual screening with Selnergy, chemoinformatics via GPDB database, phytochemistry, industrial scale-up, medicinal chemistry, and brand development. The platform integrates informatics tools (GPDB, GAINS, Selnergy) with laboratory capabilities (analytical chemistry, extraction, synthesis, formulation) to accelerate natural product discovery.

Differentiator

Problem solved

Functional benefit

Brands

• Ambinter: Online chemical procurement platform with over 30 million molecule references for drug discovery applications.
• Prestwick Chemical

Products and services

• Algosoft Marine-based patented active ingredient for cosmetics that regenerates and detoxifies skin cells, boosts ATP synthesis, stimulates autophagic activity, and protects mitochondrial and lysosomal networks from UVA damage.
• Atophylline First-in-class neutraligand active ingredient targeting chemokine CCL17, clinically proven to reduce itching and inflammation and improve skin barrier function for treating atopic dermatitis and dry skin in cosmetic applications.
• Centellane Liquid and stable version of Organic Centella asiatica extract (OCAE) designed for easy cosmetic formulation with guaranteed and stable content in active compounds.
• Dumaflorine Rejuvenating extract from black tulip flowers (Queen of the Night) that restores skin barrier function and improves dermal structure; clinically tested for anti-aging effects.
• Hibamorine Bioinspired and biosourced pure compound derived from Aomori Hiba wood by-products that provides formula protection, acts as preservative booster, reduces inflammation (TNF-α, IL-6, PGE2), and delivers anti-aging benefits via sirtuin 1 pathway.
• Hinoline 100% natural preservative-like cosmetic active ingredient that increases collagen 3 and hyaluronic acid levels, with clinically proven reduction of acne signs; beneficial for atopic and acne-prone skin.
• Lignarol Cosmetic active ingredient targeting redox pathways and disrupting Keap1/Nrf2 complex to protect from oxidative effects and improve cellular longevity, with dual-effect antioxidant properties and ROS reduction.
• Organic Centella asiatica extract (OCAE) 100% organic, COSMOS certified Centella asiatica extract with high content of asiaticoside and madecassoside, delivering anti-wrinkle, soothing, hydrating, and skin detoxification properties for cosmetics.
• Poppyderm Original anti-aging cosmetic ingredient from poppy flowers that increases hyaluronic acid expression in epidermis (19%) and papillary dermis (33%), with plumping and hydrating effects.
• Primadulcine Primrose extract active ingredient that directly inhibits 11β-hydroxysteroid dehydrogenase 1, decreasing cortisol levels in keratinocytes to reduce stress-induced skin aging and benefit oily and acne-prone skin.
• Greenpharma Natural Compound Library (GPNCL) Chemically diverse library of pure natural compounds for hit/lead discovery in drug screening, selected from 450,000 structures, with drug-like properties and resupply capability, formatted as 96-well microplates (80 molecules/plate, 5mM in DMSO).
• Greenpharma Ligand Library (LIGENDO) Compound library containing 400 human endogenous ligands selected by molecular diversity for chemogenomics and biological pathway hopping, including hormones, vitamins, peptidic derivatives, fatty acids, and carbohydrates.
• Greenpharma Plant Extract Library (GPEL) Plant extract library for high-throughput screening and lead discovery covering 200 plant species across 187 genera and 80 families, with 80 extracts per microplate representing 20 plants in 4 different polarity solvent fractions.
• Prestwick Chemical Library (PCL) Compound library containing 1,760 FDA and EMA approved drugs for HTS and HCS screening, designed for drug repurposing/repositioning with diversified marketed drugs targeting more than 600 enzymes and receptors.
• Prestwick Phytochemical Library (PPL) Set of small molecules from natural origin with drug-like features for hit/lead discovery and drug repurposing/repositioning in pharmaceutical screening applications.
• Ambinter.com Online Chemical Procurement Platform Online procurement platform providing access to over 30 million molecule references including screening compounds, building blocks, fragments, and natural products through hundreds of vetted suppliers in a single interface for drug discovery researchers.
• Cosmetic Brand Development Service Full-service brand development including active ingredient selection, formulation development, regulatory support (PIF), manufacturing support, and stability studies for cosmetics and dermocosmetics customers.
• Medicinal Chemistry Services Contract medicinal chemistry services including target-focused library building, hemisynthetic library creation, bioisostere scaffold design, custom synthesis, hit-to-lead optimization, and patent exemplification with Full Time Equivalent (FTE) project management.
• Contract R&D Services Full-service R&D under contract including active ingredient development, formulation, phytochemistry, chemoinformatics, QSAR, virtual screening, analytical chemistry, and industrial scale-up, delivered with FTE-based engagement using dedicated PhD project managers.
• Custom Synthesis and Purification Services Custom synthesis from milligram to gram scale plus on-demand natural product purification delivered using in-house chemistry expertise and analytical platform (NMR, LC/MS, HPLC, HRMS) with a designated PhD project manager throughout the collaboration.
• Proprietary Compound Libraries (Custom) Bespoke proprietary compound library design and synthesis services including targeted libraries for CNS, GPCR, and other specific domains, leveraging Greenpharma's chemoinformatics expertise and heterocyclic chemistry know-how.

Quantifiable outcome

• GPDB database contains 160,000 natural compound structures, 160,000 organisms, 13,000 biological properties, and 54,000 traditional uses
• +6 more outcomes

Named customers5 records

Segments4 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability4 records

Feature7 records

Partnerships

Four partnerships are on record, tiered core and minor.

• University of StrasbourgcoreStrategic or Co-development PartnerLong-standing R&D partnership with the University of Strasbourg for the development of Atophylline. The project originated with target validation, in silico screening, in vitro testing, and culminated in clinical studies. The collaboration with Prof. Marcel Hibert's team at the Faculty of Pharmacy of Louis Pasteur University enabled Greenpharma to complete its pharmacology expertise.
• Prof. Gérald Guillaumet (University of Orléans)coreStrategic or Co-development PartnerMember of Greenpharma's Scientific Advisory Board. Renowned expert in heterocyclic chemistry, former Director of the Institute of Organic and Analytical Chemistry (100+ scientists) and former President of the University of Orléans. Collaborates on development of proprietary bicyclic heterocyclic compound libraries (1H-imidazo[1,2-b]pyrazole, imidazo[1,2-a]imidazolin-2-one, imidazo[1,2-a]imidazole scaffolds) and bioisostere purine mimetics.
• Prof. Jacques Haiche (School of Biotechnology of Strasbourg)coreStrategic or Co-development PartnerMember of Greenpharma's Scientific Advisory Board. Professor at the School of Biotechnology of Strasbourg and former Director of the National Genopole Network. Expert in biotechnology and bioinformatics; expert counsellor to the French Ministry of Research in life sciences. Visiting professor at Vanderbilt University and Northwestern University. Author of 100+ scientific publications.
• Ambinter Supplier NetworkminorChannel Partner/ Reseller/ DistributorAmbinter, a Greenpharma brand, aggregates hundreds of carefully vetted chemical suppliers worldwide, providing access to over 30 million molecule references in a single procurement interface. Greenpharma acts as the primary point of contact for ordering, shipping, invoicing, and support, while leveraging this distributed supplier network for fulfilment.

Scale indicators8 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Evotec:
• Eurofins Discovery Services: Eurofins Discovery offers a broad suite of contract research, screening libraries and drug discovery services to pharmaceutical and biotech clients. Comparable to Greenpharma's contract R&D and compound library businesses but with substantially greater scale and global laboratory footprint.
• Givaudan Active Beauty: Givaudan Active Beauty develops and supplies cosmetic bioactives and botanical extracts globally, with deep R&D and consumer-insight capabilities. Comparable to Greenpharma's cosmetic actives offering but with a vastly larger portfolio, scale, and multinational customer footprint.
• Symrise (Diana division): Symrise, through its Diana food and fragrance divisions, develops natural bioactive ingredients for nutraceutical, food and personal care applications. Comparable to Greenpharma's botanical actives and nutraceutical segment but operates at significantly larger scale with global distribution.
• Sederma (Croda Beauty): Sederma, part of Croda, is a global leader in cosmetic active ingredients with a broad patented actives portfolio serving major cosmetics brands. It is comparable to Greenpharma's cosmetic actives business but at much larger scale, broader portfolio, and global sales coverage.
• Seppic (Air Liquide Healthcare Specialty Ingredients): Seppic, part of Air Liquide, develops specialty ingredients including botanical actives and excipients for cosmetics, pharmaceuticals and nutrition. Comparable to Greenpharma's natural-ingredient supply business, particularly in cosmetics and pharmaceutical adjacencies, with broader product lines and global reach.

Direct peers

• Indena: Indena is an Italian company specializing in botanical-derived active ingredients for pharmaceutical, nutraceutical and cosmetic markets, with proprietary extraction technologies and standardized extracts. It is a direct peer because of overlapping natural-ingredient sourcing, standardization, and supply to pharma and nutraceutical customers.
• Schrödinger: Schrödinger provides computational chemistry and molecular simulation software used in drug discovery (virtual screening, free-energy calculations). Comparable to Greenpharma's SELNERGY™ inverse docking and QSAR software tools used for in silico biological profiling and lead optimization.
• Mibelle Biochemistry: Mibelle Biochemistry is a Swiss developer and producer of bioactive cosmetic active ingredients derived from natural sources (plant cells, Swiss apple, snow algae). It is a direct peer because it offers patented/proprietary natural actives with efficacy data to cosmetics brands using a similar specialty-ingredient model.

Regional players

• Natraceutical / Monteloeder: Natraceutical/Monteloeder is a Spanish supplier of branded botanical nutraceutical ingredients with proprietary extraction and clinical substantiation. It overlaps with Greenpharma's nutraceutical customer segment and natural actives approach, but primarily serves European supplement brands.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/Greenpharma_FR
• LinkedInlinkedin.com/company/greenpharma

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Subsidiaries2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Greenpharma