Quadridox
Quadridox builds X-ray diffraction (XRD) imaging hardware and software that identify materials by their atomic signatures, serving airport security (TSA), medical diagnostics, industrial non-destructive testing, and research customers through enterprise sales and strategic partnerships.
- Company typePrivate
- Founded2018
- HeadquartersRaleigh, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Quadridox does
Quadridox is a private X-ray diffraction (XRD) imaging systems company founded in 2018 and headquartered in Hillsborough, North Carolina. The company builds hardware and software that analyze how X-rays interact with matter to reconstruct 3D models of objects and identify materials by their atomic signatures — a capability conventional density-based X-ray systems cannot achieve. Its product portfolio centers on the DELPHI baggage scanner, the compact Tabletop XRD system, the BioSpecx XRDI system, the QSim simulation tool, and a physics-based Synthetic Data Platform. Quadridox also offers custom XRD system design and integration services for specialized applications.
The company targets four vertical end markets: airport and transportation security (primary, including TSA-aligned checked baggage screening), medical diagnostics (cancer detection), industrial non-destructive testing, and research/academia. Its core technology is differentiated by material-specific diffraction 'fingerprints' that enable true materials identification with reduced false alarms versus conventional X-ray systems. Quadridox is a Duke University spinout, and its team collectively holds 12+ patents and 500+ publications.
Quadridox generates revenue through hardware sales of XRD baggage and tabletop systems, one-time software licenses for QSim and the Synthetic Data Platform, and professional services for custom XRD solutions and system integration. It operates an enterprise field sales motion targeting airports, government agencies, and industrial customers via direct 'Request a quote' engagement, with strategic partnerships (notably Leidos) serving as a key channel to global airport operators. No public pricing is disclosed, and the company is in early commercialization with its first product shipments occurring in 2025.
Quadridox firmographics
Firmographics- Name
- Quadridox
- Legal name
- Quadridox Inc.
- Website
- https://quadridox.com
- Company type
- Private
- Founded year
- 2018
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Quadridox builds X-ray diffraction (XRD) imaging hardware and software that identify materials by their atomic signatures, serving airport security (TSA), medical diagnostics, industrial non-destructive testing, and research customers through enterprise sales and strategic partnerships.
- Ownership category
- akta.pro rank
Where Quadridox is headquartered
LocationHeadquarters
- HQ city
- Raleigh
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Quadridox business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Personnel, Supply Chain, Operations, Marketing or Sales
Revenue model
- X-ray diffraction hardware systems: Sale of advanced X-ray diffraction baggage scanners, tabletop systems, and custom imaging equipment. Hardware products include the DELPHI baggage scanner and compact tabletop systems designed for security, medical diagnostics, and non-destructive testing applications.
- Software products and simulation tools: Software products including QSim simulation and modeling tools for advanced X-ray systems, as well as data acquisition, processing, and reconstruction software for next-generation X-ray imaging systems.
- Custom solutions and consulting: Collaborative custom solution development with partners, including physics modeling, computational sensing, hardware design, algorithm development, and system prototyping services.
Go-to-market motion1 record
Distribution channels1 record
Marketing channels4 records
Quadridox product offering
Product offeringCore offering
Quadridox designs, develops, and sells advanced X-ray diffraction (XRD) imaging systems that identify materials by their atomic diffraction signatures rather than density alone. Its commercial offerings include the DELPHI baggage scanner for airport security, compact tabletop XRD systems, the BioSpecx XRDI system, and the QSim simulation software and synthetic data platform for algorithm development and validation, alongside custom XRD system engineering services.
Product overview
Quadridox offers a portfolio of X-ray diffraction-based products and solutions centered on real-time, high-accuracy threat detection and materials identification. The core product line includes DELPHI (full-size baggage scanner), Tabletop X-ray Diffraction Scanner (compact system), BioSpecx XRDI System, and the Synthetic Data Platform with QSim simulation tool. These products share a common X-ray diffraction technology foundation that provides atomic-level material fingerprinting. Custom X-ray Diffraction Solutions and integration services complement the standard product offerings for specialized use cases across security, medical diagnostics, and non-destructive testing applications.
Differentiator
Problem solved
Functional benefit
Brands
- DELPHI: Quadridox's baggage scanner system for airport security screening
- BioSpecx XRDI
- QSim
Products and services
- DELPHI Advanced baggage screening system using X-ray diffraction technology for atomic-level material identification. Provides precise detection of threats, contraband, and hazardous substances with significantly reduced false alarms, targeting high-throughput airport and transportation-hub environments.
- Tabletop X-ray Diffraction Scanner Compact, portable X-ray diffraction system delivering laboratory-grade precision in a small footprint. Designed for security checkpoints, medical research, and laboratory applications requiring real-time material identification without large-scale installation.
- BioSpecx XRDI System X-ray diffraction imaging system for threat detection. First unit shipped to the UK in 2025; designed to integrate with CT systems for comprehensive baggage screening capabilities.
- Synthetic Data Platform End-to-end physics-based framework for generating complex, job-specific 3D virtual objects including virtual luggage, cargo, calibration phantoms, and security threat simulations, used for algorithm training and system validation.
- QSim Proprietary simulation and modeling tool for advanced X-ray systems. Supports data acquisition, processing, and reconstruction for next-generation X-ray imaging systems, including both hardware and software development workflows.
- Custom X-ray Diffraction Solutions Tailored X-ray diffraction system design and integration services optimized for specific operational, spatial, and analytical requirements. Scope includes physics modeling, computational sensing, hardware design, algorithm development, and system prototyping for specialized use cases.
Quantifiable outcome
- Reduced false alarms through clear material classification by atomic signatures
- +1 more outcomes
Companies that use Quadridox
Customer profileNamed customers2 records
Segments4 records
Ideal customer profiles3 records
Quadridox technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability6 records
Feature6 records
Quadridox partnerships and signals
Strategic signalPartnerships
Four partnerships are on record, tiered core and minor.
- LeidoscoreLeidos and Quadridox partnered to develop advanced baggage screening technology that integrates CT and XRDI imaging systems, aiming to improve threat detection and efficiency at airports. The integrated system is undergoing testing and is expected to be trialed at airports in 2026. The collaboration utilizes AI algorithms to enhance security and operational performance.
- HATCH (Singapore)minorQuadridox was selected for Hatch's In-Beta startup program in Singapore, representing a strategic startup ecosystem partnership in the Asia-Pacific region.
- Duke UniversityminorDuke University collaborates with Quadridox as one of the company's key collaborators and partners. Quadridox originated as a Duke spinout with research ties including featured research publications.
- Keele UniversityminorKeele University collaborates with Quadridox as a key partner. Quadridox presented breast cancer detection data at Keele's Tissue Microenvironment & Disease Workshop in the UK.
Scale indicators4 records
Recent moves6 records
Expansion highlights6 records
Quadridox competitors and assessment
Company assessmentDirect peers
- Smiths Detection: Global leader in aviation checkpoint and checked-baggage screening X-ray/CT systems (e.g., HI-SCAN, CTiX). Directly competes with Quadridox's DELPHI in airport baggage screening and represents the dominant incumbent Quadridox must displace or partner with.
- Rapiscan Systems (OSI Systems): Major supplier of airport baggage and cargo screening X-ray/CT systems (RTT, Orion). Direct competitor in the same TSA and international airport procurement processes Quadridox targets via Leidos.
- Leidos: Both Quadridox's strategic partner and a systems integrator competing in airport security solutions. The Leidos–Quadridox co-developed CT+XRDI system positions Leidos as both the primary channel and a peer in integrated security offerings.
- L3Harris Technologies (Security & Detection): Supplies computed tomography and X-ray baggage screening systems (e.g., ClearScan, ProVision) to airports and government agencies. Direct competitor in aviation security screening procurement.
- Nuctech: Chinese security inspection equipment provider with a broad X-ray/CT scanner portfolio deployed at airports globally. Competes directly with Quadridox in airport and cargo screening tenders.
- Astrophysics Inc. Specialized manufacturer of X-ray inspection systems for cargo, vehicles, and baggage at airports, ports, and border checkpoints. Direct competitor in high-energy X-ray cargo and baggage screening.
Broad incumbents
- Bruker: Established manufacturer of X-ray diffraction (XRD) and analytical instruments for materials science and industrial applications. Relevant peer for Quadridox's tabletop XRD and NDT offerings, though Bruker's primary focus is lab/research markets rather than airport security.
- Rigaku: Major manufacturer of X-ray diffraction and analytical X-ray equipment used in materials research, pharmaceuticals, and industrial QA/QC. Comparable in XRD core technology with Quadridox's tabletop systems and NDT use cases.
- Malvern Panalytical: Global supplier of analytical XRD and materials characterization instruments. Comparable to Quadridox in XRD core technology, primarily serving materials science, pharma, and industrial customers rather than aviation security.
Emerging players
- VOTI Detection: Smaller-scale challenger in X-ray security screening, focused on compact baggage and parcel inspection systems. Similar in size and stage profile to Quadridox and competes in adjacent airport, parcel, and cargo screening niches.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat5 records
Key risks6 records
Key highlights6 records
Customer concentration
Quadridox social profiles
Digital presenceQuadridox financial estimates
Financial estimateRevenue estimate
Valuation estimate
Quadridox leadership team
Management profileNumber of profiles
Profiles12 records
Quadridox funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Quadridox M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Quadridox
What does Quadridox do?
Quadridox designs, develops, and sells advanced X-ray diffraction (XRD) imaging systems that identify materials by their atomic diffraction signatures rather than density alone. Its commercial offerings include the DELPHI baggage scanner for airport security, compact tabletop XRD systems, the BioSpecx XRDI system, and the QSim simulation software and synthetic data platform for algorithm development and validation, alongside custom XRD system engineering services.
Is Quadridox a public or private company?
Quadridox is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Quadridox founded?
Quadridox was founded in 2018. It employs 11 to 50 people.
Where is Quadridox based?
Quadridox is headquartered in Raleigh, United States, in the North America region.
How does Quadridox make money?
Three revenue lines are on record. X-ray diffraction hardware systems are the primary driver. The others are software products and simulation tools and custom solutions and consulting.
Who are Quadridox's main competitors?
Direct peers on record are Smiths Detection, Rapiscan Systems (OSI Systems), Leidos, L3Harris Technologies (Security & Detection), Nuctech and Astrophysics Inc.. Broad incumbents are Bruker, Rigaku and Malvern Panalytical. VOTI Detection is listed as an emerging player.
Does Quadridox have an API?
No public API is recorded for Quadridox.