Analiza

What Analiza does

Analiza, Inc. is a privately held analytical services company founded in 2000 and headquartered in Cleveland, Ohio, specializing in physicochemical property measurement and in-vitro ADME screening for early-stage drug discovery. The company serves pharmaceutical and biotechnology clients with a portfolio of miniaturized, gold-standard assays including shake-flask thermodynamic solubility, capillary electrophoresis-based pKa, PAMPA permeability using Corning Gentest pre-coated plates, HPLC-QTOF microsomal and plasma stability, and proprietary methods for beyond-rule-of-5 compounds — notably the AlphalogD chromatography-based lipophilicity assay and SFC-based EPSA for macrocycles. Internal validation is supported by data from 1,500+ proprietary compounds demonstrating assay reproducibility (r=0.97 for solubility), and projects are typically returned within five business days.

The company operates a fee-for-service, direct-sales business model with no resellers or channel partners. Pricing is quote-based and varies by assay type, sample volume, and customization; clients submit DMSO stocks or powders directly to the Cleveland lab. Customer acquisition relies on a website contact form, phone, email, scientist-led teleconferences, and thought-leadership channels including technical blog content, peer-reviewed publications, and annual co-hosted Physicochemical Properties Workshops with PIC Analytics (since 2019). Analiza's stated scale signal is having served '100 top brands' in the pharmaceutical and biotechnology industries, and it is privately capitalized following two early JumpStart Inc. investments of $300,000 each in 2007 and 2008.

Analiza is incorporated as Analiza, Inc. in Ohio, employs 51–100 people, and shows no public listing, no disclosed parent company, no recent venture funding, and no M&A activity. Its competitive positioning is anchored in niche specialization for difficult chemical spaces (macrocycles, PROTACs, BRo5 molecules), IP-protective sample handling (no proprietary structural information required from clients), and scientific credibility maintained through publications and educational events.

Name

Analiza

Legal name

Analiza, Inc.

Website

https://analiza.com

Company type

Private

Founded year

2000

Operating status

Operating

Headcount range

51–100 employees

Short description

Analiza is a Cleveland-based privately held analytical services CRO providing miniaturized physicochemical property and in-vitro ADME assays for early-stage pharmaceutical and biotechnology drug discovery, with proprietary capabilities in beyond-rule-of-5 and macrocycle chemistry.

Ownership category

akta.pro rank

Product category

Drug Discovery Analytical Services

NAICS

Scientific Research and Development Services (5417), Testing Laboratories and Services (54138)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Testing Laboratories (8734)

akta.pro primary industry

Bioanalytical Testing (PK/ADA/NAb) (HLAGADAA)

akta.pro secondary industries

Method Development & Validation (ICH/USP) (HLAGADAB), Small-Molecule Analytical Development & Method Validation (CMC) (HLAGAHAF)

Keywords

• Drug discovery services
• Physicochemical property testing
• ADME screening services
• Solubility assays
• Permeability assays

Headquarters

HQ city

Cleveland

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Analytical Testing Services: Analiza generates revenue by providing fee-for-service analytical testing across its portfolio of physicochemical and ADME assays. Clients submit compound samples and receive quantified data within 5 business days. Pricing is quote-based, varying by assay type, number of samples, and customization requirements. The company does not require proprietary structural information from clients.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels4 records

Core offering

Analiza is an analytical services provider that performs fee-for-service physicochemical and in-vitro ADME testing for pharmaceutical and biotechnology companies engaged in early drug discovery. Clients submit compound samples to the company's Cleveland laboratory and receive quantitative data on solubility, logD/logP, pKa, microsomal stability, plasma stability, PAMPA permeability, EPSA polarity, and the proprietary AlphalogD lipophilicity assay, typically within five business days. The company also develops custom analytical methods, including forced degradation studies, for projects requiring tailored protocols.

Product overview

Analiza offers a portfolio of analytical services organized into three main categories: Physicochemical Properties (Solubility, pKa, AlphalogD), In-Vitro ADME Properties (Microsomal Stability, Plasma Stability, PAMPA, EPSA), and Custom Analytical Services. These are individual assay services rather than a unified software platform—clients submit compound samples and receive quantitative data reports. The assays are miniaturized, gold-standard methods designed for early drug discovery screening with fast turnaround times.

Differentiator

Problem solved

Functional benefit

Products and services

• Physicochemical Properties Services Comprehensive measurement of solubility, logD/logP, and pKa using miniaturized, gold-standard assays to guide early drug discovery decisions for pharmaceutical and biotechnology clients.
• In-Vitro ADME Properties Services Screening for microsomal stability, plasma stability, and membrane permeability (PAMPA) to predict in-vivo performance and identify metabolic liabilities in early discovery compounds.
• Custom Analytical Services Tailored analytical solutions including forced degradation studies and method development for unique project needs of pharmaceutical and biotechnology clients.
• Solubility Assay Miniaturized shake-flask approach for thermodynamic solubility quantified by CLND, HPLC-UV, or HPLC-MS. Requires only 15 μL of 10 mM DMSO stock.
• pKa Assay Determines ionization constants using capillary electrophoresis with a cosolvent approach for low-solubility molecules. Capillary separations run in parallel across 24 equally spaced pH levels between 1.8 and 11.2.
• AlphalogD Assay Proprietary chromatography-based assay for measuring highly lipophilic compounds and beyond-rule-of-5 (BRo5) molecules. Determines LogD at pH 7.4 in a high-throughput format.
• Microsomal Stability Assay Determines compound metabolism rates by liver microsomes across species (human, rat, mouse) using HPLC-MS QTOF workflows with full-scan data acquisition.
• Plasma Stability Assay Incubates compounds in rat, mouse, dog, or human plasma to measure degradation rates over time. Particularly relevant for prodrug characterization.
• PAMPA (Parallel Artificial Membrane Permeability Assay) Evaluates passive diffusion across an artificial lipid membrane using Corning Gentest pre-coated PAMPA plates. Measures Papp and related permeability parameters.
• EPSA (Experimental Polar Surface Area) Assay Measures shielded polarity index by supercritical fluid chromatography (SFC) using a polar Pirkle column system. Designed for macrocycles and large flexible molecules to assess intramolecular hydrogen bonding.

Quantifiable outcome

• Data returned within 5 business days for most projects
• +2 more outcomes

Named customers1 record

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

One partnership is on record.

• PIC AnalyticscoreStrategic or Co-development Partner · 1 April 2019Analiza has partnered with PIC Analytics (led by Laurence Philippe-Venec, Ph.D.) since 2019 to co-host annual Physicochemical Properties Workshops. These events focus on the applications of physicochemical properties in early drug discovery, covering topics such as lipophilicity measurement, property-based drug design, and challenges with larger molecules. The collaboration fosters interaction among industry professionals and creates opportunities for research collaborations.

Scale indicators3 records

Recent moves5 records

Expansion highlights4 records

Emerging players

• Pharmacelsus: Pharmacelsus is a specialized CRO offering in vitro and in vivo ADME/PK services for small molecules and biologics. Comparable as a focused ADME service provider to pharma/biotech, similar in size and scope to Analiza.
• Sannova Analytical: Sannova Analytical provides chromatographic, physicochemical, and impurity characterization services to the pharmaceutical industry. Comparable as a niche analytical services peer offering overlap with Analiza's physicochemical and custom analytical capabilities.
• Bienta (Enamine): Bienta, part of Enamine, provides in vitro ADME and physicochemical profiling services for drug discovery. Comparable as a focused analytical services peer addressing the same pharma/biotech discovery market as Analiza.

Broad incumbents

• WuXi AppTec: WuXi AppTec operates a large global discovery services platform including physicochemical and ADME testing. Comparable as a much larger-scale alternative offering similar physicochemical and DMPK capabilities to pharma and biotech.
• Frontage Laboratories: Frontage Laboratories is a US-based CRO providing DMPK, ADME, bioanalytical, and CMC services. Comparable as a larger, multi-service alternative to Analiza for discovery-stage ADME work with broader geographic reach.
• Thermo Fisher Scientific (PPD): Thermo Fisher's PPD division offers end-to-end discovery and clinical CRO services including DMPK/ADME. Comparable as a full-service incumbent alternative to Analiza for early discovery ADME work.
• Eurofins Discovery Services: Eurofins Discovery is a large global CRO offering ADME, physicochemical profiling, and in vitro pharmacology across a much broader portfolio than Analiza. Comparable as a competing provider of early discovery analytical services with global scale.
• Charles River Laboratories: Charles River is a major preclinical CRO with discovery services spanning ADME, DMPK, and physicochemical profiling. Comparable as a much larger, full-service alternative for the same pharmaceutical and biotech customer base.

Direct peers

• Absorption Systems: Absorption Systems specializes in ADME testing including PAMPA, Caco-2, and permeability assays for drug discovery. Directly comparable to Analiza's in-vitro ADME and permeability service line and target customer segment.
• Cyprotex (Evotec): Cyprotex, owned by Evotec, offers ADME/PK and physicochemical property testing services to pharma and biotech, directly overlapping with Analiza's solubility, logD, pKa, microsomal stability, and PAMPA assay portfolio.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/analiza

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds2 records

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Analiza