ingenious targeting laboratory
ingenious targeting laboratory is a U.S.-based CRO founded in 1998 that generates custom genetically engineered mouse and rat models — knockouts, knockins, conditional, and humanized lines on C57BL/6 backgrounds — for academic, pharmaceutical, and biotechnology research customers worldwide.
- Company typePrivate
- Founded1998
- HeadquartersRonkonkoma, United States
- Headcount11–50
- GTM typeB2B
- OfferingServices
What ingenious targeting laboratory does
ingenious targeting laboratory (iTL) is a privately held U.S.-based contract research organization founded in 1998 and headquartered in Holbrook, NY, specializing exclusively in custom genetically engineered mouse and rat model generation for biomedical research. The company delivers conventional knockouts, conditional knockouts (Cre-Lox, Flp-Frt), knockins (point mutation, cDNA, gene replacement), Rosa26 targeted transgenics, and humanized mouse models — primarily on defined C57BL/6 backgrounds — and operates an AAALAC-accredited animal facility with U.S.-based QC oversight at every project stage.
Core technology is ES cell-based gene targeting using Cre-Lox and Flp-Frt site-specific recombination, with a pre-germline characterization step that validates allele structure before mouse generation. iTL also maintains a catalog of 14,774+ pre-existing genome-engineered models (with ~2,400 live lines available for immediate shipment) and offers supporting services including cohort development, colony management, genotyping, cryopreservation/rederivation, and non-GLP preclinical services (phenotyping, PK/PD, pharmacology). A free Breeding Scheme Architect tool, launched in 2026, supports breeding planning and Mendelian ratio calculation.
The business model is project-based, quote-driven, and primarily fee-for-service. Revenue streams include custom model generation (one-time project fees), catalog model sales, preclinical services, and colony/cryopreservation services. Customer segments are academic research institutions, pharmaceutical companies, and biotechnology organizations worldwide, served through a direct inside-sales motion with scientific consultation and a 1-business-day quote response commitment. The company reports 2,800+ custom projects completed and 800+ peer-reviewed publications since inception, supported by a 100% germline transmission guarantee on all custom work.
ingenious targeting laboratory firmographics
Firmographics- Name
- ingenious targeting laboratory
- Legal name
- ingenious targeting laboratory
- Website
- https://genetargeting.com
- Company type
- Private
- Founded year
- 1998
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- ingenious targeting laboratory is a U.S.-based CRO founded in 1998 that generates custom genetically engineered mouse and rat models — knockouts, knockins, conditional, and humanized lines on C57BL/6 backgrounds — for academic, pharmaceutical, and biotechnology research customers worldwide.
- Ownership category
- akta.pro rank
Where ingenious targeting laboratory is headquartered
LocationHeadquarters
- HQ city
- Ronkonkoma
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
ingenious targeting laboratory business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales
Revenue model
- Custom Mouse Model Generation: Project-based custom gene targeting services for generating genetically engineered mouse models including conventional knockouts, conditional knockouts, knock-ins, reporter alleles, and humanized models. Pricing varies by project scope, complexity, and deliverables outlined in service agreements.
- Catalog Model Sales: Sale of pre-existing genetically engineered mouse models from catalog of 14,774+ lines. Includes knockout, knockin, humanized, Cre driver, and reporter strains available for immediate shipment from live colonies or cryopreserved materials.
- Preclinical Services: Non-GLP phenotype characterization, PK/PD studies, pharmacology, and exploratory in-vivo support services for custom or catalog animal models to support translational research decisions.
- Colony Management Services: Multi-generation cohort development, breeding services, and colony planning for study-ready cohorts with structured breeding to support statistical power and multi-site reproducibility.
- Cryopreservation Services: Cryopreservation and rederivation services for mouse line archival and health status upgrade.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Multi-year contract | Custom Project Quote |
Go-to-market motion2 records
Distribution channels3 records
Marketing channels6 records
ingenious targeting laboratory product offering
Product offeringCore offering
ingenious targeting laboratory (iTL) is a U.S.-based contract research organization that designs, generates, and delivers custom genetically engineered mouse and rat models for biomedical research. Founded in 1998 and headquartered in Holbrook, NY, the company has completed more than 2,800 custom projects and maintains a catalog of over 14,774 pre-existing models, complemented by supporting services in cohort development, preclinical research, and colony management.
Product overview
ingenious targeting laboratory is a custom mouse model company offering a dual-track portfolio: a catalog of 14,774+ pre-made genome-engineered mouse and rat models (including knockouts, knockins, humanized checkpoint models, Cre drivers, and reporter strains), and bespoke custom model generation services. Custom models span conventional knockouts, conditional knockouts (via Cre-Lox and Flp-Frt systems), knockins (point mutations, cDNA, gene replacement), Rosa26 targeted transgenics, and humanized models—all on defined C57BL/6 backgrounds. Supporting services include cohort development, colony management, genotyping, phenotyping, cryopreservation, and preclinical (non-GLP) studies. The company also provides a free Breeding Scheme Architect tool for project planning. Their technology stack centers on ES cell-based gene targeting with Cre-Lox and Flp-Frt recombination systems.
Differentiator
Problem solved
Functional benefit
Products and services
- Custom Mouse Models
Quantifiable outcome
- 100% germline transmission rate on all custom projects
- +3 more outcomes
Companies that use ingenious targeting laboratory
Customer profileNamed customers8 records
Segments3 records
Ideal customer profiles3 records
ingenious targeting laboratory technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature5 records
ingenious targeting laboratory partnerships and signals
Strategic signalScale indicators7 records
Recent moves6 records
Expansion highlights5 records
ingenious targeting laboratory competitors and assessment
Company assessmentDirect peers
- Taconic Biosciences: Direct competitor offering custom mouse and rat model generation, catalog models, and colony management services to pharma, biotech, and academic researchers—closely aligned with iTL's custom model and colony service offering.
- Biocytogen: Direct competitor specializing in humanized mouse models and immuno-oncology preclinical services, particularly for checkpoint and bispecific antibody testing—directly overlaps with iTL's humanized checkpoint franchise.
- Cyagen Biosciences: Direct competitor in custom mouse and rat model generation, including CRISPR-based knockouts/knockins and humanized models; targets the same academic and pharma customer base as iTL with similar project-based services.
- Ozgene: Australia-based custom mouse and rat model generation CRO with Cre-Lox and other gene targeting capabilities; closely comparable service offering targeting academic and pharma researchers worldwide.
- Genoway: European-based custom mouse model provider offering transgenic, knockin, knockout, and humanized models; competes with iTL on global academic and pharma accounts seeking custom rodent model generation.
- GemPharmatech: China-based CRO with one of the world's largest mouse model catalogs (20,000+ lines) and custom model generation services; competes with iTL particularly on catalog volume and global pricing for academic accounts.
Emerging players
- Applied StemCell: Smaller specialty provider offering custom mouse/rat model generation and CRISPR-based gene editing services; partial overlap with iTL on custom model creation but with a more limited catalog and customer base.
Broad incumbents
- Charles River Laboratories: Global CRO with a Research Models & Services segment providing custom mouse models, catalog models, and preclinical services; competes across iTL's full offering but as part of a much broader CRO portfolio.
- The Jackson Laboratory: Largest nonprofit provider of genetically engineered mouse models with a massive catalog and in-vivo services; competes with iTL on both catalog and custom mouse generation, but operates at much greater scale and breadth across disease areas.
- Crown Bioscience (JSR Life Sciences): Preclinical CRO offering syngeneic, xenograft, and humanized mouse models for oncology and immuno-oncology research; overlaps with iTL on humanized and syngeneic tumor models as part of a larger preclinical services portfolio.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks7 records
Key highlights7 records
Customer concentration
ingenious targeting laboratory social profiles
Digital presenceingenious targeting laboratory compliance and trust
Trust signalCompliance1 record
ingenious targeting laboratory financial estimates
Financial estimateRevenue estimate
Valuation estimate
ingenious targeting laboratory leadership team
Management profileNumber of profiles
Profiles1 record
ingenious targeting laboratory funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
ingenious targeting laboratory M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about ingenious targeting laboratory
What does ingenious targeting laboratory do?
ingenious targeting laboratory (iTL) is a U.S.-based contract research organization that designs, generates, and delivers custom genetically engineered mouse and rat models for biomedical research. Founded in 1998 and headquartered in Holbrook, NY, the company has completed more than 2,800 custom projects and maintains a catalog of over 14,774 pre-existing models, complemented by supporting services in cohort development, preclinical research, and colony management.
Is ingenious targeting laboratory a public or private company?
ingenious targeting laboratory is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was ingenious targeting laboratory founded?
ingenious targeting laboratory was founded in 1998. It employs 11 to 50 people.
Where is ingenious targeting laboratory based?
ingenious targeting laboratory is headquartered in Ronkonkoma, United States, in the North America region.
How does ingenious targeting laboratory make money?
Five revenue lines are on record. Custom Mouse Model Generation is the primary driver. The others are catalog Model Sales, preclinical Services, colony Management Services and cryopreservation Services.
Who are ingenious targeting laboratory's main competitors?
Direct peers on record are Taconic Biosciences, Biocytogen, Cyagen Biosciences, Ozgene, Genoway and GemPharmatech. Applied StemCell is listed as an emerging player. Broad incumbents are Charles River Laboratories, The Jackson Laboratory and Crown Bioscience (JSR Life Sciences).
Does ingenious targeting laboratory have an API?
No public API is recorded for ingenious targeting laboratory.