TCG Lifesciences

What TCG Lifesciences does

TCG Lifesciences Private Limited (formerly Chembiotek Research International), headquartered in Kolkata, India and founded in 2001, is a privately held global Contract Research Organization and CDMO operating under The Chatterjee Group. The company delivers integrated end-to-end drug discovery and development services spanning medicinal and custom chemistry, molecular pharmacology, in vitro and in vivo pharmacology, DMPK and bioanalytical services, safety pharmacology and toxicology, solid-phase peptide synthesis, and cGMP manufacturing through its wholly-owned subsidiary TCG GreenChem Manufacturing Pvt. Ltd. in Hyderabad, which is US FDA-inspected. TCGLS employs 1,300+ scientists including 300+ PhDs and operates a 7.5-acre manufacturing campus with ~200 KL reactor volume, AAALAC-accredited animal facilities, electrophysiology and BSL-2 laboratories, cGMP kilo labs, and stacks of ISO certifications (ISO/IEC 27001:2022, ISO 45001, ISO 14001, ISO 50001). The platform is differentiated by integrated discovery-to-commercial capability, a 20-patent portfolio that includes a world patent for brivaracetam API, 54 peer-reviewed publications, and partnerships spanning kinase profiling (Carna Biosciences), CNS discovery (JSW Life Sciences), and affordable-medicines manufacturing (Medicines for All Institute at VCU).

The business model is fee-for-service B2B, professional-services revenue from pharmaceutical and biotechnology clients globally, supplemented by managed-services revenue from CDMO engagements through TCG GreenChem. Pricing is project-specific quote-based rather than publicly disclosed, with customer acquisition driven by a direct business-development team ([email protected]), industry conferences (CPHI Barcelona and Frankfurt), and thought-leadership content. The company serves primary customer segments of large and mid-size pharmaceutical companies, biotechnology companies, and specialty chemicals manufacturers, with therapeutic area focus on Inflammation & Pain, Infectious Diseases, CNS, and Oncology. Geographic reach spans India (HQ and manufacturing), the United States, Europe, and Japan. AI/ML capability is offered as a supporting feature layer within computational drug discovery — including in silico screening, structure-based design, and ADMET prediction — rather than as a core delivery model.

Name

TCG Lifesciences

Legal name

TCG Lifesciences Private Limited

Website

https://tcgls.com

Company type

Private

Founded year

2001

Operating status

Operating

Headcount range

501–1,000 employees

Short description

TCG Lifesciences is a privately held India-based global CRO and CDMO delivering integrated drug discovery, preclinical, and cGMP manufacturing services to pharmaceutical, biotechnology, and specialty chemicals clients across India, the US, Europe, and Japan.

Ownership category

akta.pro rank

Headquarters

HQ city

Kolkata

HQ country

India

HQ region

Asia

Offices5 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Contract Research Services (CRO): Fee-for-service contract research spanning medicinal chemistry, preclinical discovery, DMPK, and analytical services to pharmaceutical and biotech companies globally
2. Contract Development and Manufacturing (CDMO): cGMP manufacturing services for APIs, intermediates, and regulatory starting materials through TCG GreenChem Manufacturing subsidiary

Go-to-market motion1 record

Distribution channels2 records

Marketing channels5 records

Core offering

TCG Lifesciences (formerly Chembiotek Research International) is a global Contract Research and CDMO company delivering integrated end-to-end R&D services to the pharmaceutical, biotechnology, and specialty chemicals industries. The company provides medicinal and process chemistry, custom and library synthesis, solid phase peptide synthesis, in vitro and in vivo pharmacology, DMPK and bioanalytical services, safety and toxicology assessments, computational drug discovery, and cGMP manufacturing of APIs, intermediates, and regulatory starting materials through its TCG GreenChem Manufacturing subsidiary.

Product overview

TCG Lifesciences is a global Contract Research and CDMO company delivering end-to-end R&D solutions to the pharmaceutical and specialty chemicals industries. The company's integrated service portfolio includes Chemistry Services (custom synthesis, medicinal chemistry, process R&D, cGMP kilo scale, compound management), Preclinical Discovery (molecular pharmacology, DMPK, in vivo pharmacology, safety/toxicology), Platform Technologies (solid phase peptide synthesis), and Manufacturing through its TCG GreenChem Manufacturing subsidiary (US FDA-inspected cGMP API production). TCGLS also offers computational and bioinformatics services for drug discovery. The company operates world-class facilities in India (Kolkata, Pune) with more than 1,300 scientists, serving global pharmaceutical and biotech clients across therapeutic areas including Inflammation & Pain, Infectious Diseases, CNS, and Oncology.

Differentiator

Problem solved

Functional benefit

Brands

• TCG GreenChem: CMC development services including process research & development and delivery of cGMP APIs
• TCG GreenChem Manufacturing
• Clininvent

Products and services

• Chemistry Services Integrated medicinal chemistry services including custom synthesis, library synthesis, analytical development, process research and development, cGMP kilo scale synthesis (20L to 200L reactors, -80°C to +200°C), and compound management for global pharmaceutical and biotech clients.
• Preclinical Discovery Services Comprehensive preclinical research services including molecular pharmacology, DMPK, in vivo pharmacology, safety pharmacology, and toxicology supporting drug discovery programs from hit generation to preclinical candidate selection across therapeutic areas including inflammation and pain, infectious diseases, CNS, and oncology.
• Drug Metabolism & Pharmacokinetics (DMPK) Services In vitro ADME services (solubility, permeability, metabolic stability, drug-drug interactions), in vivo pharmacokinetics in rodents, bioanalytical LC-MS services, and toxicokinetics for preclinical drug discovery, with an in-house rodent breeding facility.
• Safety and Toxicology Services In vitro safety assessment including cardiovascular safety (hERG, NaV1.5), genetic toxicology (AMES test), and in vitro toxicology (hemolysis, cell viability, phospholipidosis) for regulatory submission preparation.
• Solid Phase Peptide Synthesis (Platform Technologies) Solid phase peptide synthesis platform with expertise in both solid and solution phase synthesis, including linear peptides, cyclic peptides, macrocycles, stapled peptides, nucleoside derivatives, and cyclic dinucleotides for pharmaceutical and biotech customers.
• TCG GreenChem Manufacturing (CDMO) US FDA-inspected contract manufacturing at the wholly owned TCG GreenChem Manufacturing Pvt. Ltd. subsidiary in Hyderabad, producing cGMP Active Pharmaceutical Ingredients (APIs) including NCEs, generic APIs, regulatory starting materials, and intermediates for pharmaceutical and specialty chemicals industries. Combined 200 KL reactor volume, ~8,000 m² plant footprint, and 600 m² pack-out clean room across a 7.5-acre facility.
• Molecular Pharmacology Services Cellular and molecular biology services including assay development, cell line development, GPCR and ion channel screening, enzyme assays, and therapeutic area expertise spanning cardiovascular, CNS, inflammation and pain, infectious diseases, and oncology using platforms such as Alphascreen, Beta arrestin, cAMP, ELISA, HTRF/TR-FRET, and Surface Plasmon Resonance (SPR).
• Computational Drug Discovery Services In silico drug discovery services including structure-based drug design, ligand-based pharmacophore approaches, virtual screening of 2 million+ compound libraries, PROTAC screening, and AI/ML-guided ADMET prediction for target identification and hit generation.
• TCG GreenChem USA — CMC Development Services CMC development services including process research and development and delivery of cGMP APIs from the US-based TCG GreenChem, Inc. subsidiary (NJ & VA), serving pharmaceutical customers requiring cross-border development-to-manufacturing support.

Quantifiable outcome

• 20+ years of experience delivering integrated drug discovery services to global clients

Named customers3 records

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability6 records

Feature5 records

Partnerships

Four partnerships are on record, tiered core and minor.

• JSW Life Sciences (Austria)coreStrategic or Co-development Partner · 1 January 2011Strategic alliance for Central Nervous System (CNS) drug discovery services, extending TCGLS capabilities in neuroscience research area
• Carna Biosciences, Inc. (Japan)coreStrategic or Co-development Partner · 1 January 2010Strategic alliance for kinase-based drug discovery services, providing access to specialized kinase profiling capabilities for clients
• Mantrax Ventures (Australia)minorGTM or Marketing Partner · 1 January 2010Business development partnership in Australia for market expansion and client acquisition in the region
• Medicines for All Institute at Virginia Commonwealth UniversitycoreStrategic or Co-development PartnerCross-sector collaboration to deliver critical medicines for treatment of HIV, COVID-19, and other diseases to less developed nations at affordable cost via green and sustainable manufacturing processes. TCG GreenChem, Inc. provides process development and CMC expertise.

Scale indicators6 records

Recent moves9 records

Expansion highlights5 records

Broad incumbents

• WuXi AppTec / WuXi STA: Large global CRO/CDMO with extensive discovery, biology, and small-molecule API manufacturing services; a broad incumbent competing in the same R&D outsourcing category as TCG but at significantly greater scale.
• Cambrex: Global small-molecule API/intermediate CDMO with multiple manufacturing sites and process development services; a broad incumbent serving similar pharma clients as TCG GreenChem, though with deeper commercial-scale capacity.
• Eurofins Discovery: Global CRO/CDMO network offering medicinal chemistry, DMPK, safety pharmacology, and bioanalytical services; overlaps with TCG's discovery-side capabilities but operates at substantially larger scale across many more geographies.

Direct peers

• Piramal Pharma Solutions: India-headquartered CDMO with global manufacturing sites offering API development, drug-product manufacturing, and integrated development services; overlaps with TCG GreenChem's small-molecule API/intermediate CDMO focus and competes for Western pharma outsourcing deals.
• Syngene International: India-headquartered CRO/CDMO offering integrated discovery, development, and manufacturing services to global pharma; the most direct Indian-headquartered peer to TCG Lifesciences across medicinal chemistry, DMPK, biology, and commercial-scale API manufacturing (notably co-founded historically by a current TCG GreenChem MD).
• Sai Life Sciences: Hyderabad-based CRO/CDMO providing medicinal chemistry, biology, DMPK, and API manufacturing to global pharma and biotech; competes head-to-head with TCG GreenChem for India-sourced small-molecule API and discovery chemistry programs.
• Curia (formerly Albany Molecular Research): Global CRO/CDMO providing small-molecule drug discovery, process R&D, and cGMP API manufacturing; competes with TCG for Western pharma outsourcing contracts and offers comparable end-to-end integrated services.
• Aragen Life Sciences (formerly GVK Biosciences): Hyderabad-based CRO/CDMO with discovery, development, and manufacturing capabilities serving global pharma and biotech; competes with TCG across medicinal chemistry, biology, and small-molecule API manufacturing.
• Jubilant Biosys: India-based CRO subsidiary of Jubilant Pharma offering integrated drug discovery including medicinal chemistry, DMPK, and in-vivo pharmacology; directly comparable to TCG's discovery-side offering.
• Anthem Biosciences: Bangalore-based integrated CRO/CDMO with discovery services, DMPK, safety assessment, and API manufacturing; comparable scale, India footprint, and end-to-end service model targeting global pharma R&D outsourcing.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key highlights7 records

Customer concentration

• Xtwitter.com/TCGLifesciences
• YouTubeyoutube.com/channel/UC5AWwONnrqE_vOPTGIFni3Q
• Facebookfacebook.com/TCGCRO
• LinkedInlinkedin.com/company/tcg-lifesciences-limited

Compliance8 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Subsidiaries3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about TCG Lifesciences