Interventional Orthobiologics Foundation

What Interventional Orthobiologics Foundation does

The Interventional Orthobiologics Foundation (IOF) is a 501(c)(3) non-profit organization founded in 2015 and headquartered in the Denver/Greenwood Village, Colorado area. IOF provides standardized, CME-accredited education and competency-based training to physicians (MD/DO) practicing musculoskeletal medicine, interventional spine, orthopedics, sports medicine, and related fields in image-guided regenerative orthopedic procedures using orthobiologics such as bone marrow aspirate, adipose tissue, and platelet rich plasma. Core deliverables include a stepwise Physician Education Program (Fundamental through Expert tiers), the annual IOF MAX conference, and an Augmented Reality Injection Trainer launched in 2025 that overlays needle trajectory onto live ultrasound imaging to replace cadaver-based procedural training.

The foundation monetizes through six streams: recurring membership subscriptions (Active, Fellow, Fellowship, Associate, Student), per-course CME training fees, the annual IOF MAX conference (registration, sponsorships, and post-event video sales), on-site AR injection training priced at $10,000 per day for up to five attendees, and tiered corporate sponsorships ($500–$2,000). Distribution is direct-to-physician through its Broomfield, CO training academy, regional on-site programs, the annual global conference, and a digital video storefront. IOF states that IOF MAX is the largest orthobiologics conference worldwide, and lead instructor Dr. Don Buford has trained over 2,500 clinicians in MSK ultrasound over a 15-year period.

IOF is governed by a Board of Directors chaired by President Mary A. Ambach, MD, with executive leadership under Executive Director Jillian Abramson, MBA (since March 2018), and a board that includes academic and clinical figures from Emory University, Harvard/Spaulding, Centeno-Schultz Clinic, and Colorado State University. IOF publishes guidelines, ethics standards, peer-reviewed research grants, and the Atlas of Interventional Orthopedics textbook, and offers scholarships for residents and fellows. A strategic co-development partnership with The Orthobiologic Institute (TOBI) will merge the 2027 conference under the IOF MAX with TOBI banner.

Name

Interventional Orthobiologics Foundation

Legal name

Interventional Orthobiologics Foundation

Website

https://interventionalorthobiologics.org

Company type

Private

Founded year

2015

Operating status

Operating

Headcount range

11–50 employees

Short description

IOF is a 501(c)(3) non-profit founded in 2015 that delivers CME-accredited, competency-based training and the IOF MAX conference to physicians practicing image-guided regenerative orthopedics using orthobiologics.

Ownership category

akta.pro rank

Product category

Physician Continuing Medical Education

NAICS

Professional and Management Development Training (611430), All Other Schools and Instruction (61169)

SIC

Services-Educational Services (8200)

akta.pro primary industry

Healthcare & Clinical Simulation (Surgery, Nursing, EMT, Patient Interaction) (EDAFAJAC)

Keywords

• Regenerative medicine education
• Physician training programs
• MSK ultrasound training
• Orthobiologic injection courses
• CME accredited education

Headquarters

HQ city

Denver

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Others, Infrastructure

Revenue model

1. Membership Fees: Annual membership subscriptions providing access to training courses, conferences, educational videos, webinars, guidelines, standards, and the network of IOF members. Membership tiers include Active, Fellow, Fellowship, Fellowship-eligible, Associate, and Student categories.
2. Physician Education Courses: CME-accredited hands-on training courses at fundamental, intermediate, and advanced levels covering various anatomical regions. Courses include pre-course didactic videos, cadaver labs, and hands-on training with image guidance. Members receive discounted pricing.
3. Annual Conference (IOF MAX): Annual conference revenue from attendee registration fees for general sessions and cadaver labs. Sponsors and exhibitors also pay to participate.
4. Conference Video Sales: Sale of video recordings from annual conferences for personal viewing by those who did not attend in person. Videos available at different price points for members vs. non-members.
5. On-Site AR Injection Training: Day rate pricing for on-site augmented reality injection training programs at institutions, clinics, and fellowship programs. Includes up to 5 attendees and 10-hour training day.
6. Corporate Sponsorships: Corporate partners sponsor training courses, scholarships for residents/fellows, or webinar series. Sponsorship tiers include Course Sponsor ($2,000), Course Benefactor ($1,000), and Course Exhibitor ($500).

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels7 records

Core offering

IOF provides standardized CME-accredited competency-based physician education in image-guided interventional orthobiologics, delivering hands-on cadaver-lab courses from Fundamental through Expert levels across multiple anatomical regions, the Augmented Reality Injection Trainer for on-site MSK ultrasound training, and the annual IOF MAX conference. Memberships, sponsorships, video sales, research grants, and donations fund the organization's training and standards-setting mission.

Product overview

The Interventional Orthobiologics Foundation (IOF) is a 501(c)(3) non-profit organization offering a unified portfolio of evidence-based education and training products in regenerative orthobiologic medicine. The core offerings include the IOF MAX Experience annual conference (the largest orthobiologics conference worldwide), a competency-based Physician Education Program with courses ranging from Fundamental to Expert levels covering various body regions (shoulder, elbow, hip, knee, spine, wrist, hand, ankle, foot), and the Augmented Reality Injection Trainer for on-site MSK ultrasound training. These products are complemented by scholarship programs for residents/fellows, research grants, an Ultrasound Library, and membership benefits. The education curriculum is standardized and CME-accredited, designed to train physicians in image-guided injection techniques using orthobiologics like bone marrow aspirate, adipose, and platelet rich plasma.

Differentiator

Problem solved

Functional benefit

Products and services

• IOF MAX Experience Annual Conference The annual IOF MAX Experience conference brings together leading physicians and scientists in regenerative medicine for evidence-based presentations, hands-on cadaver labs, abstract presentations, and networking. It is sold as a standalone conference registration with tickets for attendees, scholarships for residents and fellows, and separate video recordings available for purchase after the event.
• Physician Education Program CME-accredited competency-based curriculum offering hands-on cadaver-lab training, pre-course didactic videos, webinars, and procedure guidance across Fundamental, Intermediate, Advanced, and Expert levels covering shoulder, elbow, hip, knee, spine, wrist, hand, ankle, foot, and bone marrow aspirate/adipose harvesting techniques. Open to MD/DO physicians with MSK specialty and ultrasound training.
• Augmented Reality Injection Trainer On-site training package combining an IOF instructor, ultrasound machine, and proprietary augmented reality technology that displays needle trajectory on live ultrasound images. Sold at $10,000 per day base for up to 5 attendees, with optional upgrades to a formal CME-accredited IOF intermediate-level course for additional fees. Targeted at institutions, clinics, and fellowship programs.
• IOF Membership Program Annual professional membership giving physicians recognition among patients and peers, access to guidelines, standards, ethics resources, the findable IOF member directory, and discounted pricing on courses, conferences, and video purchases. Tiered across Active, Fellow, Fellowship, Fellowship-eligible, Associate, and Student categories.
• Ultrasound Library Online educational resource library containing ultrasound training materials, didactic videos, and reference content covering MSK ultrasound imaging and injection techniques for orthobiologic procedures.

Named customers4 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability2 records

Feature1 record

Partnerships

Two partnerships are on record, tiered core and minor.

• TOBI (The Orthobiologic Institute)coreStrategic or Co-development Partner · 1 January 2026IOF MAX with TOBI 2027 is a joint conference combining the expertise of both organizations. TOBI (The Orthobiologic Institute) is a premier educational organization in regenerative medicine, and this partnership creates what IOF describes as the largest orthobiologics conference in the world. The 2027 edition is scheduled for February 18-21 in Nashville, Tennessee.
• Corporate SponsorsminorGTM or Marketing PartnerCorporate partners sponsor IOF training courses at various levels (Course Sponsor $2,000, Course Benefactor $1,000, Course Exhibitor $500). Sponsors receive company visibility through promotional documents, course website, handouts, and exhibit space. Partners can also sponsor scholarships for residents/fellows or webinar series.

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Spine Intervention Society (SIS): International society providing CME-accredited training in interventional spine procedures. Comparable as a competency-based, image-guided interventional training body serving overlapping physician specialties (interventional spine, PM&R, anesthesia).
• American Medical Society for Sports Medicine (AMSSM): Multispecialty sports medicine society offering CME and physician education. Comparable because sports medicine physicians are a core IOF member segment, and AMSSM provides overlapping MSK ultrasound and injection training resources.
• American Academy of Orthopaedic Surgeons (AAOS): Largest orthopaedic surgeon specialty society globally, providing CME, courses, and member education. Comparable as the incumbent orthopedic education body covering the broader orthopaedic specialty that many IOF members practice within.
• North American Spine Society (NASS): Major multidisciplinary spine society offering CME, guidelines, and member education. Comparable as a specialty society serving interventional spine physicians who are core members of IOF, though with broader scope beyond orthobiologics.
• American Academy of Physical Medicine and Rehabilitation (AAPM&R): Large specialty society providing PM&R physician CME, training standards, and member resources. Comparable as a physician membership and education body serving the same PM&R and MSK specialties IOF targets, but with a much broader scope.
• American Institute of Ultrasound in Medicine (AIUM): Multispecialty ultrasound society offering CME courses, accreditation, and guidelines. Directly relevant because MSK ultrasound is the core imaging modality in IOF's training, and many IOF physician members overlap with AIUM's ultrasound-trained audience.

Others

• Arthrex: Orthopedic medical-device company with a substantial physician education program including cadaver labs, surgical simulation, and CME courses. Comparable as an adjacent industry player that competes for physician training time and corporate sponsorship dollars in orthopedics.
• International Society for Stem Cell Research (ISSCR): Global organization promoting excellence in stem cell research and clinical translation. Comparable as a thematically related scientific and educational body whose guidelines and audience intersect with orthobiologic regenerative medicine, even though IOF focuses on clinical injection training.

Direct peers

• TOBI (The Orthobiologic Institute): Premier education organization in regenerative and orthobiologic medicine. Co-hosts IOF MAX with TOBI 2027 with IOF, making it the most directly comparable peer in mission, audience (physicians), and product (orthobiologics conferences and training).
• Regenerative Medicine Foundation: Non-profit focused on advancing regenerative medicine through education, events, and policy. Directly comparable as a mission-aligned non-profit running conferences and physician education in the same regenerative-medicine space.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/iofoundation
• Facebookfacebook.com/iofoundation
• LinkedInlinkedin.com/company/interventional-orthopedics-foundation

Revenue estimate

Valuation estimate

Number of profiles

Profiles9 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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