Center for International Blood & Marrow Transplant Research

What Center for International Blood & Marrow Transplant Research does

CIBMTR (Center for International Blood & Marrow Transplant Research) is a non-profit research collaboration between the Medical College of Wisconsin (MCW) and the National Marrow Donor Program (NMDP), founded in 1972 and headquartered in Milwaukee, WI with a secondary coordinating center in Minneapolis. The organization maintains the world's largest outcomes database for hematopoietic cell transplantation (HCT) and cellular therapies, with records on more than 750,000 patients representing nearly all allogeneic transplants and approximately 80% of autologous transplants performed in the US. Core technology infrastructure includes the Outcomes Database, the CIBMTR Biorepository (approximately 3 million sample aliquots from 60,000+ recipient/donor pairs), FormsNet for electronic data submission, AGNIS (an open-source standards-based messaging system), and the CIBMTR Portal for center-facing analytics. Bioinformatics and clinical risk calculator tools support donor matching, outcome prediction, and biomarker discovery.

CIBMTR operates through a community-led research model with more than 3,000 researchers participating on Working Committees and 320+ transplant centers worldwide submitting standardized data via TED and CRF forms. The organization is the Data and Coordinating Center for the BMT CTN clinical trials network (with NMDP and Emmes) and holds the SCTOD federal contract from HRSA mandating US allogeneic transplant data collection. CIBMTR facilitates 3 CMS Coverage with Evidence Development (CED) studies that have enabled Medicare reimbursement for more than 10,000 cell and gene therapy patients.

The revenue model combines federal grants and contracts (NIH, HRSA, US Office of Naval Research), corporate memberships (five annual tiers for pharma/biotech), fee-based industry services (registry data access, real-world evidence studies, CRO services), data licensing and biospecimen sales (with academic/industry pricing tiers), and reimbursements to transplant centers for completed Comprehensive Report Forms. CIBMTR concurrently collects data on approximately 35,000 new patients annually and conducts 195 ongoing studies and clinical trials at any given time, serving four primary segments: transplant centers, pharmaceutical/biotech companies, clinical researchers, and patients/families.

Name

Center for International Blood & Marrow Transplant Research

Legal name

Center for International Blood & Marrow Transplant Research

Website

https://cibmtr.org

Company type

Private

Founded year

1972

Operating status

Operating

Headcount range

101–250 employees

Short description

CIBMTR is a non-profit research collaboration between the Medical College of Wisconsin and NMDP that maintains the world's largest cellular therapy outcomes database (750,000+ patients) and biospecimen repository, supporting transplant centers, pharmaceutical/biotech companies, clinical researchers, and federal partners through standardized data collection, CRO services, and Working Committee-led studies.

Ownership category

akta.pro rank

Product category

Cellular Therapy Research and Clinical Outcomes Data

NAICS

Medical Laboratories (621511), Other Scientific and Technical Consulting Services (54169)

SIC

Services-Medical Laboratories (8071), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Clinical CROs (Phase I–IV) (HLAGAAAA)

akta.pro secondary industry

Clinical Data Management, Biostatistics & Statistical Programming CROs (HLAGAAAF)

Keywords

• Cellular therapy research
• Transplant outcomes data
• Clinical research services
• Biorepository samples
• Real-world evidence data

Headquarters

HQ city

Milwaukee

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure, Marketing or Sales, Supply Chain

Revenue model

1. Government Grants and Contracts: CIBMTR is funded through NIH awards, US Office of Naval Research grants, and HRSA contracts (including the Stem Cell Therapeutic Outcomes Database contract). This represents the primary funding source for core operations.
2. Corporate Membership Program: Annual memberships at five different levels provide corporations access to current data on blood and bone marrow transplantation and participation in CIBMTR annual meetings. The memberships support CIBMTR research.
3. Industry Collaboration Services: CIBMTR provides registry data and real-world evidence, research planning and support, and clinical research organization (CRO) services to industry collaborators on a contractual basis. Services include deidentified datasets, retrospective/prospective studies, and clinical trial support.
4. Data Licensing and Reimbursement: Centers are reimbursed for completed Comprehensive Report Forms. CIBMTR also provides fee-based access to biospecimen samples for researchers, with academic and industry pricing tiers.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels6 records

Core offering

CIBMTR operates a research collaboration that collects, maintains, and analyzes clinical outcomes data from hematopoietic cell transplantation and cellular therapies worldwide, with a database of more than 750,000 patients and a Biorepository of approximately 3 million sample aliquots. It sells this data, biospecimen access, and end-to-end clinical trial support services to pharmaceutical, biotech, and academic clients through a Corporate Membership Program, CRO Services, and biospecimen licensing, while enabling observational and prospective research through volunteer Working Committees.

Product overview

CIBMTR is a research collaboration between the Medical College of Wisconsin and NMDP that offers a unified research platform focused on cellular therapy and hematopoietic stem cell transplantation. The core offering is the Outcomes Database containing data from over 750,000 patients, complemented by a Biorepository with millions of biological samples. Supporting platforms include the CIBMTR Portal for center operations, FormsNet for data submission, and AGNIS for standards-based data exchange. Additional offerings include CRO Services for clinical trials, Working Committee Studies for observational research, standardized Data Collection Forms, Research Tools & Calculators for clinical risk assessment, a Corporate Membership Program for industry access, and Publicly Available Datasets for secondary analysis.

Differentiator

Problem solved

Functional benefit

Products and services

• CIBMTR Outcomes Database
• CIBMTR Biorepository
• CIBMTR Clinical Research Organization (CRO) Services
• Working Committee Studies
• Corporate Membership Program
• Data Collection Forms
• Research Tools & Calculators
• Patient-Reported Outcomes (PRO) Data Collection
• Publicly Available Datasets
• Center-Specific Survival Analysis
• Summary Slides & Reports
• Center Membership

Quantifiable outcome

• CIBMTR has facilitated more than 2,000 publications since 1972, with freely available publication analysis datasets for secondary analysis
• +2 more outcomes

Named customers6 records

Segments5 records

Ideal customer profiles5 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Ten partnerships are on record, tiered strategic and core.

• Cure Sickle Cell Initiative (National Heart, Lung, and Blood Institute)strategicStrategic or Co-development Partner · 1 January 2018CIBMTR has worked with the Cure Sickle Cell Data Consortium since 2019 to build a research data ecosystem. In 2024, awarded NIH funding for long-term follow-up program planning for sickle cell patients treated with HCT or gene therapy.
• Medical College of Wisconsin (MCW)coreStrategic or Co-development PartnerCIBMTR is a research collaboration between MCW and NMDP. MCW provides the statistical expertise through the Division of Biostatistics, hosts the Milwaukee coordinating center, and contributes scientific directors and statistical directors to Working Committees.
• NMDP (National Marrow Donor Program)coreStrategic or Co-development PartnerCIBMTR is a research collaboration between MCW and NMDP. NMDP provides access to the donor registry, the Biorepository operations, and hosts the Minneapolis coordinating center. Together they operate the BMT CTN Data and Coordinating Center.
• Health Resources and Services Administration (HRSA)coreStrategic or Co-development PartnerCIBMTR holds the SCTOD contract awarded by HRSA to collect data on all allogeneic transplants performed in the US and products procured through the C.W. Bill Young Cell Transplantation Program. This is a federally-funded contract under the TRANSPLANT Act of 2021.
• Blood and Marrow Transplant Clinical Trials Network (BMT CTN)coreStrategic or Co-development PartnerCIBMTR manages the BMT CTN Data and Coordinating Center with NMDP and The Emmes Company. BMT CTN conducts multicenter Phase II and III trials with broad national participation. CIBMTR supports the network with access to Outcomes Database and clinical trial management services.
• The Emmes CompanycoreImplementation/ SI/ Consulting PartnerContract research organization that partners with CIBMTR and NMDP in managing the BMT CTN Data and Coordinating Center. Provides clinical research expertise for multi-institutional trials.
• Centers for Medicare & Medicaid Services (CMS)strategicStrategic or Co-development PartnerCIBMTR facilitates 3 CMS CED studies allowing Medicare coverage for patients enrolled in clinical studies. More than 10,000 patients received transplants with CMS reimbursement through these studies. Also coordinates with CMS Innovation Center for Cell and Gene Therapy Access Model for sickle cell disease.
• American Society for Transplantation and Cellular Therapy (ASTCT)coreStrategic or Co-development PartnerASTCT co-hosts the annual Tandem Meetings with CIBMTR, combining the Transplantation & Cellular Therapy Meetings. ASTCT Spotlight Sessions focus on cutting-edge clinical and translational research at these meetings.
• Worldwide Network for Blood and Marrow Transplantation (WBMT)strategicStrategic or Co-development PartnerCIBMTR is a founding member of WBMT, collaborating with worldwide organizations to exchange and increase data worldwide for cellular therapy research.
• Medical College of Wisconsin Division of BiostatisticscoreStrategic or Co-development PartnerCIBMTR has a collaborative association with MCW Division of Biostatistics since 1985. Biostatisticians ensure statistical integrity of CIBMTR scientific activities and have pioneered novel methodologic approaches to analyzing cellular therapy data.

Scale indicators10 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• IQVIA: IQVIA is a global CRO and real-world evidence provider that competes for the same pharma/biotech RWE and clinical trial services budget as CIBMTR, but with broader therapeutic and geographic coverage.
• PPD / Thermo Fisher Scientific Clinical Research: PPD (now part of Thermo Fisher) is a global CRO with deep experience in hematology and cell/gene therapy trials, competing with CIBMTR CRO Services for industry-sponsored trial work.
• Flatiron Health: Flatiron operates oncology-focused EHR-derived real-world evidence datasets and offers research services to life sciences companies, competing with CIBMTR for cell-therapy RWE contracts in hematology/oncology.

Emerging players

• Tempus: Tempus combines molecular profiling with real-world clinical and genomic data for pharma R&D, increasingly competing with CIBMTR-style registries for cell and gene therapy evidence generation.

Direct peers

• NMDP / Be The Match: NMDP is CIBMTR's parent collaboration partner and operates the world's largest bone marrow donor registry; the two share governance and operations but NMDP focuses on donor recruitment and cell sourcing while CIBMTR focuses on outcomes research.
• The Emmes Company: Emmes is a CRO that co-manages the BMT CTN Data and Coordinating Center with CIBMTR and NMDP, providing clinical research operations for multi-institutional transplant trials directly adjacent to CIBMTR's CRO Services.
• Center for International Bone Marrow Transplant Registry sibling — Worldwide Network for Blood and Marrow Transplantation (WBMT): WBMT is a global network that aggregates transplant outcomes data worldwide; CIBMTR is a founding member and works with WBMT on cross-registry studies, making it both collaborator and partially overlapping data registry.
• Blood and Marrow Transplant Clinical Trials Network (BMT CTN): BMT CTN is a multi-center clinical trials network sponsored by NHLBI/NCI that CIBMTR helps coordinate; it is both a customer and a closely overlapping research infrastructure for HCT clinical trials.
• European Society for Blood and Marrow Transplantation (EBMT): EBMT maintains the parallel European registry for hematopoietic stem cell transplantation outcomes, with overlapping patient datasets, similar Working Committee structures, and comparable industry data-access offerings.

Others

• American Society for Transplantation and Cellular Therapy (ASTCT): ASTCT co-hosts the Tandem Meetings with CIBMTR and serves as the professional society for transplant clinicians; it is a partner rather than competitor but is the convening organization around the same clinical audience.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/CIBMTR
• Facebookfacebook.com/theCIBMTR
• LinkedInlinkedin.com/company/thecibmtr

Revenue estimate

Valuation estimate

Number of profiles

Profiles12 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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