RTI

What RTI does

RTI (operating as Rtilab) is a South Dakota-based veterinary and biomedical contract research laboratory founded in 1994 by South Dakota State University faculty. The company operates a dual-revenue model combining fee-for-service laboratory testing with the manufacture and sale of proprietary biological reagents. Its ISO 17025:2017 accredited diagnostic laboratory offers customized microbiological testing across animal health, food safety, seed health, aquaculture, milk quality, environmental monitoring, and ethanol production, using standardized methods (FDA-BAM, AOAC, USP, ISO, CMMEF) and instrumentation including the VIDAS 30 system and anaerobic chambers. The research laboratory performs antiviral, immunology, virology, and bioanalytical assays (ELISA, PCR, flow cytometry, virus isolation/neutralization, IHC) supporting preclinical and clinical studies.

Rtilab also produces and sells a catalog of proprietary monoclonal antibodies targeting livestock pathogens of commercial significance — including BC 6-4 (Bovine Coronavirus), AT13-A, SDOW17, SR30 (PRRSV), EC K88 (E. coli K88ac), RV 11-2 (Rotavirus), and PCV2 (Porcine Circovirus 2) — along with peripheral blood mononuclear cells (PBMCs) and pulmonary alveolar macrophage (PAM) cells, with optional conjugation services (FITC, biotin, HRP). Pricing is quote-based and undisclosed; products ship via FedEx with handling fees. The company serves veterinary diagnostics, food and feed safety, seed biologics, aquaculture, and biomedical research customers, with international product distribution.

Since 2022, RTI has operated as part of the Clinglobal group following Clinvet's equity investment, and in 2023 its clinical research unit was rebranded as Clinvet South Dakota while the laboratory adopted the Rtilab trade name. Distribution is direct (B2B enterprise sales) via website, phone, and email, leveraging the Clinglobal corporate network for cross-selling and platform support. The company's competitive position rests on its accredited lab status, SDSU-rooted scientific leadership (CSO Chris Chase, DVM, PhD), and proprietary antibody catalog serving the swine and bovine research markets.

Name

RTI

Legal name

RTI LLC

Website

https://4rtilab.com

Company type

Private

Founded year

1994

Operating status

Operating

Headcount range

11–50 employees

Short description

RTI (Rtilab) is an ISO 17025:2017-accredited veterinary and biomedical contract laboratory in South Dakota providing diagnostic testing, bioanalytical research services, and proprietary monoclonal antibodies and cell products to animal health, food safety, and biomedical research clients.

Ownership category

akta.pro rank

Product category

Veterinary Diagnostics and Laboratory Services

NAICS

Testing Laboratories and Services (541380), Veterinary Services (54194)

SIC

Services-Testing Laboratories (8734), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Toxicology & Therapeutic Drug Monitoring (HLAMADAG)

Keywords

• Veterinary diagnostics
• Contract research services
• Biologics manufacturing
• Animal health testing
• Monoclonal antibodies

Headquarters

HQ city

Brookings

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Supply Chain, Marketing or Sales

Revenue model

1. Laboratory Testing Services: Provides diagnostic and research laboratory services across multiple sectors including food safety, animal health, veterinary medicine, seed health, aquaculture, and bioanalytical research. Services include routine testing, customized projects, microbial challenge testing, shelf-life testing, efficacy testing, and specialized assays.
2. Product Sales: Sale of biological products including monoclonal antibodies (BC 6-4, AT13-A, SDOW17, SR30, EC K88, RV 11-2, PCV2), peripheral blood mononuclear cells (PBMCs), and pulmonary alveolar macrophage (PAM) cells. Products available as ascites fluid, cell culture supernatant, with conjugation options (FITC, biotin, HRP).

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels3 records

Core offering

RTI (operating as Rtilab) is a research-based veterinary laboratory services company and biologics manufacturer providing ISO 17025:2017 accredited diagnostic testing and research laboratory services for animal health, food safety, seed health, aquaculture, and biomedical research sectors. The company produces proprietary monoclonal antibodies, peripheral blood mononuclear cells (PBMCs), pulmonary alveolar macrophage (PAM) cells, and offers custom antibody conjugation services for research and diagnostic applications.

Product overview

Rtilab (formerly RTI LLC) is a research-based laboratory services company and biologics manufacturer operating as part of the Clinglobal group since 2022. The company offers a dual portfolio of laboratory testing services and biologics products. The service portfolio comprises two core offerings: a Diagnostic Laboratory (ISO 17025:2017 accredited) providing food safety testing, milk quality testing, environmental/air quality testing, animal health/veterinary diagnostics, seed health testing, aquaculture testing, ethanol microbial testing, and bioanalytical/research assays; and a Research Laboratory providing antiviral, immunology, and virology research services. The biologics product portfolio includes monoclonal antibodies against bovine coronavirus (BC 6-4), PRRSV (AT13-A, SDOW17, SR30), E. coli K88ac (EC K88), rotavirus (RV 11-2), and porcine circovirus 2 (PCV2), as well as Pulmonary Alveolar Macrophage (PAM) cells and Peripheral Blood Mononuclear Cells (PBMCs). The company also offers antibody conjugation services (FITC, biotin, HRP).

Differentiator

Problem solved

Functional benefit

Products and services

• Diagnostic Laboratory Services ISO 17025:2017 accredited laboratory offering customized testing, microbial challenge testing, shelf-life testing, efficacy testing, MIC testing, mycology (yeast and mold counts and IDs), bacteriology, veterinary microbiology, environmental microbiology, seed health biologics, food microbiology, pathogen testing via VIDAS 30, and spoilage organism testing for animal health, food safety, and agricultural clients.
• Research Laboratory Services Research laboratory providing antiviral assays, mechanism of action assays, anti-mycotoxin assays, anti-parasitic assays, IgG and IgA ELISA, PCR assays, serum neutralization, flow cytometry, lymphocyte proliferation assays, phenotypic and functional characterization of immune cells, cell viability and cytotoxicity assays, virus isolation, propagation, titration, ICC/IHC, and molecular identification for biomedical and veterinary research clients.
• Food Safety Testing Services Food safety testing using FDA-BAM, AOAC, USP, ISO, and CMMEF methods for detection of Bacillus cereus, Campylobacter, Clostridium perfringens, Coliforms, Cronobacter sakazakii, E. coli, E. coli O157, Enterobacteriaceae, Listeria, Salmonella, Staphylococcus aureus, and other pathogens and spoilage organisms for food producers and processors.
• Milk Quality Testing Services Comprehensive milk quality testing including bedding cultures, bulk tank cultures, coliform counts, mastitis cultures, milk Mycoplasma cultures, sanitation screens, standard plate counts, antimicrobial susceptibility testing, Prototheca testing, Streptococcus agalactiae testing, and four-panel contagious mastitis PCR for dairy operations.
• Seed Health Testing Services Seed health testing following NSHS and ISTA methods, including bacterial cultures, fungal cultures, nematode detection, and seed biologics shelf-life and formulation testing for seed companies and agricultural clients.
• Aquaculture Testing Services Aquaculture testing services including Aeromonas testing, Vibrio testing, heterotrophic counts, and probiotics testing for aquaculture operations and aquatic health management.
• Ethanol Microbial Testing Services Ethanol production microbial testing including lactic acid bacterial counts and identification and yeast counts for ethanol producers and biofuel manufacturers.
• Bioanalytical and Research Assay Services Comprehensive bioanalytical services including assay development and validation, immunofluorescence assays, ELISA, virus isolation/identification/propagation, aerobic and anaerobic culturing, isolation and identification, agglutination, Kirby-Bauer susceptibility, MIC susceptibility testing, flow cytometry, cytokine analysis, lymphocyte proliferation, cytotoxicity/cell viability, molecular biology, hematology (CBCs, slide differentials), and serology (serum neutralization) for biomedical research clients.
• Bovine Coronavirus (BCV) Monoclonal Antibody (BC 6-4) Monoclonal antibody BC 6-4 reacting with North American strains of Bovine Coronavirus, recognizing an epitope on the nucleocapsid protein. Produced as mouse ascites fluid (unconjugated). Isotype IgG1. For IHC, IFA, and ELISA applications in veterinary diagnostics and research.
• PRRSV Monoclonal Antibody (AT13-A) Monoclonal antibody AT-13 recognizing a highly conserved conformational epitope within the nucleocapsid protein of PRRSV, with cross-reactivity to European, European-like, and North American isolates. Produced as mouse ascites fluid. Isotype IgM. For immunoprecipitation, IFA, and ELISA applications.
• PRRSV Monoclonal Antibody (SDOW17) Monoclonal antibody SDOW17 reacting with over 99% of North American and European PRRSV isolates, recognizing a conserved epitope on the nucleocapsid protein. Available as unconjugated ascites fluid or FITC-conjugated. Isotype IgG1. For IFA and ELISA applications.
• PRRSV Monoclonal Antibody (SR30) Monoclonal antibody SR30 reacting with essentially all North American and European PRRSV strains, recognizing a conserved epitope on the nucleocapsid protein. Available as unconjugated ascites fluid or FITC-conjugated. Isotype IgG1. For IFA and ELISA applications.
• E. coli K88ac Monoclonal Antibody (EC K88) Anti-K88ac monoclonal antibody against K88 fimbriae of enterotoxigenic E. coli (ETEC), blocking binding of K88+ bacteria to intestinal epithelial cells. Produced in hybridoma cells as cell culture supernatant. Isotype IgG1. For IFA use at 1:100 dilution.
• Rotavirus (RV) Monoclonal Antibody (RV 11-2) Monoclonal antibody RV 11-2 reacting with Group A strains of rotavirus, recognizing an epitope on the VP6 protein. Produced as mouse ascites fluid (unconjugated). Isotype IgG2a. For IFA and ELISA applications.
• Porcine Circovirus 2 (PCV2) Monoclonal Antibody Monoclonal antibody PCV2 reacting with porcine circovirus 2 virus. Produced as mouse ascites fluid (unconjugated). Isotype IgG2. For IFA use at 1:1000 dilution.
• Pulmonary Alveolar Macrophage (PAM) Cells Pulmonary alveolar macrophage cells available for purchase as a primary cell product for research applications in virology, immunology, and respiratory disease research.
• Peripheral Blood Mononuclear Cells (PBMCs) Peripheral blood mononuclear cells available for purchase as a primary cell product for immunology, cell biology, and biomedical research applications.
• Antibody Conjugation Services Custom antibody conjugation services for FITC (fluorescein isothiocyanate), biotin, and enzyme labels (HRP), enabling tailored reagent preparation for research and diagnostic laboratories.
• Environmental and Air Quality Testing Environmental monitoring services including media fill testing incubation and reading, media qualification, microbial enumeration, microbial identification, and plate incubation for industrial and manufacturing clients.
• Animal Health and Veterinary Medicine Services Bacteria and virus testing in health and disease for preclinical and diagnostic purposes, supporting clinical trials and helping veterinarians and animal producers manage diseases across sample types including nasal, fecal, milk, urine, and blood samples.
• Specialized Laboratory Projects Custom specialized projects utilizing instruments like VIDAS 30 and anaerobic chambers, including efficacy studies, susceptibility testing, agglutination, shelf-life studies, microbial challenge, minimum inhibitory concentrations, mycotoxin binding studies, cytokine microarrays, customized molecular assays, and custom assay design for clients with bespoke research and testing needs.

Quantifiable outcome

• ISO 17025:2017 accreditation for diagnostic laboratory

Named customers1 record

Segments5 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

One partnership is on record.

• Clinvet South Dakota (Clinvet SD)coreStrategic or Co-development Partner · 1 January 2023As of 2023, RTI LLC's clinical research unit became Clinvet South Dakota (Clinvet SD). Rtilab diagnostic services support Clinvet studies and help veterinarians or producers manage diseases in their animals. The clinical research unit operates as part of the integrated Clinglobal/Clinvet network.

Scale indicators3 records

Recent moves8 records

Expansion highlights4 records

Broad incumbents

• SGS: Global testing, inspection, and certification company with food, agricultural, and environmental testing services; overlaps with RTI's food safety, seed health, and environmental microbiology offerings.
• Eurofins Scientific: Global testing laboratory conglomerate with extensive food safety, agricultural, and veterinary testing capacity; competes with RTI for food microbiology and seed health testing contracts across multiple geographies.
• Zoetis: Largest global animal health company with diagnostics, biologics, and reference lab services (Vetscan, reference labs); overlaps with RTI's veterinary diagnostics and monoclonal antibody reagent offerings as a much larger incumbent.
• IDEXX Laboratories: Dominant veterinary diagnostics company offering reference lab testing, in-clinic instruments, and livestock/poultry testing; overlaps with RTI's veterinary microbiology and diagnostics portfolio but serves a vastly broader customer base.
• Antech Diagnostics: Veterinary diagnostics laboratory network (owned by Mars Petcare) providing clinical and production-animal testing; competes with RTI for veterinary microbiology and diagnostic testing volume across North America.

Direct peers

• Inotiv: Preclinical CRO (formed from Envigo and contract research services) offering animal model research, safety assessment, and lab services; comparable to RTI's contract research and preclinical lab capabilities for animal health sponsors.
• Life Diagnostics Inc. Manufacturer of veterinary and life science diagnostic reagents and assay kits including custom antibody development; comparable to RTI's proprietary monoclonal antibody and biologics product line.
• Charles River Laboratories: Global preclinical/animal research CRO with large veterinary and livestock health research services; competes with RTI for animal health lab services and contract research work, though at much larger scale.
• Biovet (Antech): Specialized veterinary diagnostics laboratory (acquired by Antech/Mars) focused on production animal and poultry testing in North America; directly comparable to RTI's livestock diagnostic testing and microbiology services.

Regional players

• VDx Veterinary Diagnostics: Veterinary diagnostics laboratory focused on production animals and pathology services primarily in the western US; comparable specialty veterinary diagnostics niche to RTI but with regional rather than national reach.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about RTI