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Helixmith

Full company profile

uuid000dyel

Namestring
Helixmith
Websiteurl
helixmith.com
Company typeenum
Private
Founded yearint
1996
Descriptiontext

Helixmith is a privately held biotechnology company founded in 1996 and headquartered in Mapo, Seoul, South Korea, operating with a small team of 11–50 employees. The company is positioned within the regenerative medicine and cell therapy sector, with its primary disclosed focus on treatments for Critical Limb Ischemia (CLI) — a severe form of peripheral artery disease characterized by reduced blood flow, non-healing wounds, and risk of limb amputation. Third-party market research lists Helixmith among the participating companies in the global CLI therapy market alongside larger peers such as Baxter, Hemostemix, Caladrius Biosciences, Vericel Corporation, Ixaka, and Lifecells, in a market estimated at approximately USD 1,845M in 2023 with projected growth through 2034.

The company's therapeutic approach centers on cell-based interventions intended to restore microcirculation, promote tissue regeneration, and prevent amputation in CLI patients. No specific product candidates, clinical trial readouts, technology platform details, regulatory designations, manufacturing footprint, or pricing models are disclosed in the available data. The corporate website currently serves only a security verification page, indicating limited accessible company-level information, and there are no disclosed partners, distributors, or commercial agreements. Founder, CEO, and board member Jong Mook Kim is the only named member of the leadership team in the source material.

The business model cannot be determined from the available data. There is no disclosure of commercial revenue, licensing deals, or capital-raising events, and the firm has no identified customers, payors, or contracted channels. In aggregate, Helixmith presents as a small, founder-led, single-indication clinical-stage biotech with significant information gaps that prevent a more granular assessment of pipeline stage, capitalization, or commercial readiness.

Short descriptiontext

Helixmith is a Seoul-based private biotechnology company developing cell therapy and regenerative medicine treatments for Critical Limb Ischemia, serving patients with severe peripheral artery disease and high unmet medical need.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
11–50
akta.pro rankint
HeadquartersMapo, South Korea
HQ citystring
Mapo
HQ countrystring
South Korea
HQ regionstring
Asia
Markets served

Serves global market

Keyword5 values
regenerative medicine, cell therapy, gene therapy, biopharmaceuticals, tissue engineering
Industry3 codes
1Cell & Tissue Banking (biobanking, cord blood/tissue)
CodeHLAAAGAEPrimaryYes
2Library & Diversity Generation Platforms (display libraries, DNA-encoded libraries for biologics, variant libraries)
CodeHLAAAIALPrimaryNo
3Recombinant Protein Therapeutics (enzymes, hormones, growth factors)
CodeHLAAAAABPrimaryNo
NAICS code2 codes
  • Biological Product (except Diagnostic) Manufacturing325414
  • Research and Development in Biotechnology (except Nanobiotechnology)541714
SIC code2 codes
  • Biological Products, (No Disgnostic Substances)2836
  • Services-Commercial Physical & Biological Research8731
Product category
Regenerative Medicine / Cell Therapy
No data
Cost components3 values
Technology or R&D, Personnel, Operations
GTM typeB2B
B2B
Offering typeServices
Services
Core offering1 text field

Helixmith is a biotechnology company that develops regenerative medicine and cell/gene therapy treatments, with primary focus on therapies for Critical Limb Ischemia (CLI). The company's products are designed to restore microcirculation, promote tissue regeneration, and prevent limb amputation in patients with severe peripheral artery disease, addressing a clinical area with limited treatment options and high unmet medical need.

Differentiator
Functional benefit
Problem solved
Product and service1 record
1Critical Limb Ischemia Cell Therapy
CategoryRegenerative Medicine / Cell Therapy
Description

Cell-based regenerative therapy in development to treat Critical Limb Ischemia (CLI), a severe form of peripheral artery disease, aimed at restoring blood flow, promoting tissue regeneration, and preventing limb amputation in patients with high unmet medical need.

Scale indicator1 record

Each record includes

Type, Value, Description, Source

Expansion highlight1 record

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

Clinical-stage cell therapy company developing regenerative medicine treatments, including programs in critical limb ischemia and other ischemic conditions. Directly comparable to Helixmith in modality, indication, and stage of development.

TypeDirect peer
Description

Commercial-stage cell therapy company focused on autologous cell-based treatments. Comparable in cell therapy modality and regenerative medicine positioning, and explicitly listed alongside Helixmith in the CLI market.

TypeDirect peer
Description

Clinical-stage cell therapy company developing regenerative stem cell treatments for critical limb ischemia and other ischemic conditions. Directly comparable indication and modality.

TypeDirect peer
Description

Cell and gene therapy company developing targeted, multi-cell therapies for serious diseases including ischemic conditions. Listed alongside Helixmith as a key company in the CLI market.

TypeDirect peer
Description

Company developing cell-based therapies for vascular conditions including critical limb ischemia. Directly listed alongside Helixmith in the CLI market research.

TypeBroad incumbent
Description

Large global medical products and therapies company with significant presence in vascular and surgical therapies. Listed as a key player in the CLI market and represents a resource-heavy incumbent competitor.

TypeEmerging player
Description

Cell therapy company developing placenta-derived cell therapies for ischemic and inflammatory conditions including CLI. Comparable in regenerative cell therapy modality with partial indication overlap.

TypeBroad incumbent
Description

Commercial and late-stage cell therapy company with a portfolio of mesenchymal lineage cell therapies for inflammatory and vascular diseases. Comparable modality with broader portfolio reach.

TypeEmerging player
Description

Clinical-stage regenerative medicine company developing MultiStem cell therapy for ischemic and inflammatory indications. Comparable in cell-based regenerative approach to vascular disease.

TypeEmerging player
Description

Cell therapy company developing autologous adipose-derived regenerative cell therapies for ischemic conditions. Modality-comparable peer with overlapping vascular disease focus.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat2 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights5 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment1 record

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile2 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles1 record

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Helixmith

Regenerative Medicine / Cell Therapyhelixmith.com

Helixmith is a Seoul-based private biotechnology company developing cell therapy and regenerative medicine treatments for Critical Limb Ischemia, serving patients with severe peripheral artery disease and high unmet medical need.

What Helixmith does

Helixmith is a privately held biotechnology company founded in 1996 and headquartered in Mapo, Seoul, South Korea, operating with a small team of 11–50 employees. The company is positioned within the regenerative medicine and cell therapy sector, with its primary disclosed focus on treatments for Critical Limb Ischemia (CLI) — a severe form of peripheral artery disease characterized by reduced blood flow, non-healing wounds, and risk of limb amputation. Third-party market research lists Helixmith among the participating companies in the global CLI therapy market alongside larger peers such as Baxter, Hemostemix, Caladrius Biosciences, Vericel Corporation, Ixaka, and Lifecells, in a market estimated at approximately USD 1,845M in 2023 with projected growth through 2034.

The company's therapeutic approach centers on cell-based interventions intended to restore microcirculation, promote tissue regeneration, and prevent amputation in CLI patients. No specific product candidates, clinical trial readouts, technology platform details, regulatory designations, manufacturing footprint, or pricing models are disclosed in the available data. The corporate website currently serves only a security verification page, indicating limited accessible company-level information, and there are no disclosed partners, distributors, or commercial agreements. Founder, CEO, and board member Jong Mook Kim is the only named member of the leadership team in the source material.

The business model cannot be determined from the available data. There is no disclosure of commercial revenue, licensing deals, or capital-raising events, and the firm has no identified customers, payors, or contracted channels. In aggregate, Helixmith presents as a small, founder-led, single-indication clinical-stage biotech with significant information gaps that prevent a more granular assessment of pipeline stage, capitalization, or commercial readiness.

Helixmith firmographics

Firmographics
Name
Helixmith
Website
https://helixmith.com
Company type
Private
Founded year
1996
Operating status
Operating
Headcount range
11–50 employees
Short description
Helixmith is a Seoul-based private biotechnology company developing cell therapy and regenerative medicine treatments for Critical Limb Ischemia, serving patients with severe peripheral artery disease and high unmet medical need.
Ownership category
akta.pro rank

Helixmith industry classification

Industry
Product category
Regenerative Medicine / Cell Therapy
NAICS
Biological Product (except Diagnostic) Manufacturing (325414), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
SIC
Biological Products, (No Disgnostic Substances) (2836), Services-Commercial Physical & Biological Research (8731)
akta.pro primary industry
Cell & Tissue Banking (biobanking, cord blood/tissue) (HLAAAGAE)
akta.pro secondary industries
Library & Diversity Generation Platforms (display libraries, DNA-encoded libraries for biologics, variant libraries) (HLAAAIAL), Recombinant Protein Therapeutics (enzymes, hormones, growth factors) (HLAAAAAB)

Keywords

  • Regenerative medicine
  • Cell therapy
  • Gene therapy
  • Biopharmaceuticals
  • Tissue engineering

Where Helixmith is headquartered

Location

Headquarters

HQ city
Mapo
HQ country
South Korea
HQ region
Asia

Markets served

Helixmith business model

Business model
GTM type
B2B
Offering type
Services
Cost components
Technology or R&D, Personnel, Operations

Helixmith product offering

Product offering

Core offering

Helixmith is a biotechnology company that develops regenerative medicine and cell/gene therapy treatments, with primary focus on therapies for Critical Limb Ischemia (CLI). The company's products are designed to restore microcirculation, promote tissue regeneration, and prevent limb amputation in patients with severe peripheral artery disease, addressing a clinical area with limited treatment options and high unmet medical need.

Differentiator

Problem solved

Functional benefit

Products and services

  • Critical Limb Ischemia Cell Therapy Cell-based regenerative therapy in development to treat Critical Limb Ischemia (CLI), a severe form of peripheral artery disease, aimed at restoring blood flow, promoting tissue regeneration, and preventing limb amputation in patients with high unmet medical need.

Companies that use Helixmith

Customer profile

Segments1 record

Ideal customer profiles2 records

Helixmith technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Helixmith partnerships and signals

Strategic signal

Scale indicators1 record

Expansion highlights1 record

Helixmith competitors and assessment

Company assessment

Direct peers

  • Caladrius Biosciences: Clinical-stage cell therapy company developing regenerative medicine treatments, including programs in critical limb ischemia and other ischemic conditions. Directly comparable to Helixmith in modality, indication, and stage of development.
  • Vericel Corporation: Commercial-stage cell therapy company focused on autologous cell-based treatments. Comparable in cell therapy modality and regenerative medicine positioning, and explicitly listed alongside Helixmith in the CLI market.
  • Hemostemix Inc. Clinical-stage cell therapy company developing regenerative stem cell treatments for critical limb ischemia and other ischemic conditions. Directly comparable indication and modality.
  • Ixaka: Cell and gene therapy company developing targeted, multi-cell therapies for serious diseases including ischemic conditions. Listed alongside Helixmith as a key company in the CLI market.
  • Lifecells LLC: Company developing cell-based therapies for vascular conditions including critical limb ischemia. Directly listed alongside Helixmith in the CLI market research.

Broad incumbents

  • Baxter International: Large global medical products and therapies company with significant presence in vascular and surgical therapies. Listed as a key player in the CLI market and represents a resource-heavy incumbent competitor.
  • Mesoblast: Commercial and late-stage cell therapy company with a portfolio of mesenchymal lineage cell therapies for inflammatory and vascular diseases. Comparable modality with broader portfolio reach.

Emerging players

  • Pluristem Therapeutics: Cell therapy company developing placenta-derived cell therapies for ischemic and inflammatory conditions including CLI. Comparable in regenerative cell therapy modality with partial indication overlap.
  • Athersys: Clinical-stage regenerative medicine company developing MultiStem cell therapy for ischemic and inflammatory indications. Comparable in cell-based regenerative approach to vascular disease.
  • Cytori Therapeutics: Cell therapy company developing autologous adipose-derived regenerative cell therapies for ischemic conditions. Modality-comparable peer with overlapping vascular disease focus.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat2 records

Key risks5 records

Key highlights5 records

Customer concentration

Helixmith financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Helixmith leadership team

Management profile

Number of profiles

Profiles1 record

Helixmith funding detail

Funding detail

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Helixmith M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Helixmith

What does Helixmith do?

Helixmith is a biotechnology company that develops regenerative medicine and cell/gene therapy treatments, with primary focus on therapies for Critical Limb Ischemia (CLI). The company's products are designed to restore microcirculation, promote tissue regeneration, and prevent limb amputation in patients with severe peripheral artery disease, addressing a clinical area with limited treatment options and high unmet medical need.

When was Helixmith founded?

Helixmith was founded in 1996. It employs 11 to 50 people.

Where is Helixmith based?

Helixmith is headquartered in Mapo, South Korea, in the Asia region.

Who are Helixmith's main competitors?

Direct peers on record are Caladrius Biosciences, Vericel Corporation, Hemostemix Inc., Ixaka and Lifecells LLC. Broad incumbents are Baxter International and Mesoblast. Emerging players are Pluristem Therapeutics, Athersys and Cytori Therapeutics.

Does Helixmith have an API?

No public API is recorded for Helixmith.

What industry is Helixmith in?

Helixmith's product category is Regenerative Medicine / Cell Therapy. Its primary akta.pro industry code is HLAAAGAE, Cell & Tissue Banking (biobanking, cord blood/tissue), with a secondary code of HLAAAIAL, Library & Diversity Generation Platforms (display libraries, DNA-encoded libraries for biologics, variant libraries). Its NAICS code is 325414 and its SIC code is 2836.

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Live signals
NaverHelixmith, Genome & Company Surge on Royalty [K-bio pulse]Korean pharmaceutical stocks Helixmith, Genome & Company, and SG Healthcare rose on Sept. 30 on licensing and royalty prospects. Helixmith gained 18.85% on royalties from its Chinese partner's gene therapy launch, Genome & Company rose 13.59% ahead of an ADC conference, and SG Healthcare climbed 13% after securing exclusive rights to a particle therapy system.NateHelixmith, Genome & Company Surge on Royalty [K-bio pulse] : 네이트 뉴스Helixmith, Genome & Company, and SG Healthcare all rose on licensing and partnership news. Helixmith gained 18.85% on royalties from its Chinese partner's gene therapy launch, Genome & Company rose 13.59% on ADC licensing talks, and SG Healthcare climbed 13% after securing exclusive Korean rights to a particle therapy system.openPR.comCritical Limb Ischemia Market: High-Growth Opportunities for Investors to 2034 - DelveInsight | Baxter, Ixaka, Hemostemix Inc., Caladrius Biosciences, Vericel Corporation, Helixmith, Lifecells, LLCDelveInsight published a market research report on Critical Limb Ischemia, valued at approximately USD 1,845 million in 2023, projecting significant growth through 2034 driven by increasing disease prevalence and a rich pipeline of emerging therapies.PR NewswireHelixmith to Present New ALS-Focused Development Program at Upcoming ConferencesHelixmith announced that CEO Dr. Sunyoung Kim will present their ALS-focused development program DART at the 2022 Cell & Gene Meeting on the Mesa and the 2022 BIO-Europe Conference. The DART program uniquely investigates three therapeutic modalities in parallel—plasmid DNA, AAV vector, and humanized antibodies—targeting the HGF/c-Met signaling pathway for ALS treatment. The company has completed Phase 1 and Phase 2a trials with their plasmid DNA therapy (Engensis/VM202) and has funding for respiratory studies in ALS patients, though they will need to raise additional capital to advance the other two modalities through clinical development.PR NewswireHelixmith Announces Topline Results from Double-Blind Placebo Controlled Multicenter Study for TADIOS Involving 100 Subjects Infected with COVID-19Helixmith announced topline results from a double-blind placebo-controlled multicenter study for TADIOS, a proprietary botanical formulation, involving 100 subjects with mild to moderate COVID-19 infection conducted in India. The study found TADIOS was safe and well tolerated, with statistically significant improvements in IL-1RA biomarker levels (over 3-fold reduction compared to placebo, p<0.05) and fatigue symptoms at 14-day follow-up. The company plans to present full data at an academic conference or in a journal publication and believes TADIOS could serve as a niche therapeutic for COVID-19 treatment amid continuing variant emergence and breakthrough infections.PR NewswireHelixmith Announces VM202 (Engensis®) Presentation at New York Academy of Sciences "Advances in Pain" Meeting on May 3, 2022Helixmith announced that Dr. Jack Kessler of Northwestern University will present clinical data on the company's gene therapy product VM202 (Engensis) at the New York Academy of Sciences Advances in Pain Meeting on May 3, 2022. The Phase 3 extension trial (DPN 3-1b) showed significant and sustained pain reduction in patients with painful diabetic peripheral neuropathy at 6, 9, and 12 months, with the analgesic effect lasting more than 8 months beyond the final treatment. The company is currently conducting a second Phase 3 clinical trial based on cumulative efficacy and safety evidence from the completed studies.PR NewswirePaper Reporting Results from Helixmith's Phase 3 Gene Therapy Trial for Painful Diabetic Neuropathy was One of the Top-10 Most-Downloaded Articles in Clinical and Translational ScienceHelixmith announced that its publication regarding the Phase 3 gene therapy trial for painful diabetic neuropathy was among the top-10 most-downloaded articles in Clinical and Translational Science in 2021. The study demonstrated that VM202 provided pain reduction for over eight months with a favorable safety profile, particularly benefiting patients not currently using pregabalin or gabapentin. Helixmith is concurrently launching additional Phase 3 trials for the condition in the US.PR NewswireHelixmith Announces 50% Enrollment in its Clinical Trial for COVID-19, involving TADIOSHelixmith Co., Ltd. announced that 50 subjects have been enrolled out of a planned 100 in its double-blind placebo-controlled COVID-19 clinical trial for TADIOS, a proprietary botanical treatment, being conducted at four trial sites in India under Ministry of AYUSH regulations. The trial is evaluating TADIOS as an adjuvant to standard COVID-19 treatment in patients with mild to moderate symptoms, measuring biochemical indicators including TNF-alpha, CRP, and IL-6, as well as clinical symptom improvement using a WHO-designed 8-point scale. Pre-clinical studies published in the Journal of Ethnopharmacology showed TADIOS inhibited lung damage in an acute lung injury mouse model through control of inflammatory and oxidative molecules via the Nrf2-HO-1 pathway.PR NewswireHelixmith Co. Ltd announces positive topline data from world's first gene therapy phase 1 study for CMTHelixmith announced positive topline data from the world's first phase 1 gene therapy study for Charcot-Marie-Tooth (CMT) disease involving its lead product Engensis. The trial, conducted in South Korea with 12 participants, demonstrated that the treatment was safe and well-tolerated while showing trends of improvement in neuropathy symptoms and potential slowing of muscle degeneration. Helixmith is now considering a larger phase 2 study to verify these observations.PR NewswireGene and Cell Therapies Expected to Offer New Treatment Paradigm in CNS Disorders; Market Expected to Increase at a CAGR of 45% During the Study Period 2018-2026 in the 7MMDelveInsight's market research report projects the Gene and Cell Therapies Targeting CNS Disorders market to grow at a CAGR of 45% during 2018–2026, with a 2020 valuation of USD 988.8 million across the 7MM (US, EU5, and Japan). The US holds approximately 85% of market share, with Novartis' Zolgensma being the first approved gene replacement therapy for Spinal Muscular Atrophy at ~USD 2.125 million per patient. Multiple companies including BrainStorm Cell Therapeutics, Helixmith, and Axovant are advancing therapies through Phase II and III trials for conditions such as ALS, Alzheimer's, Parkinson's, and spinal cord injury, though challenges including high treatment costs and blood-brain barrier penetration remain significant barriers.