Zyris
Zyris is a privately-held medical device company that designs, manufactures, and sells the Isolite dental isolation system, combining LED illumination, dual-channel suction, and retraction to serve general and pediatric dental practices, DSOs, and U.S. government dental clinics across 20+ countries.
- Company typePrivate
- Founded2001
- HeadquartersGoleta, United States
- Headcount51–100
- GTM typeB2B
- OfferingHardware or Manufacturing
What Zyris does
Zyris is a privately-held medical device company founded in 2001 and headquartered in Santa Barbara, California, that designs, manufactures, and sells the Isolite family of dental isolation systems. The company's flagship technology combines integrated LED illumination, dual-channel continuous suction, tongue and cheek retraction, and an integrated bite block into a single hand-free device that interfaces with standard high-volume evacuator (HVE) ports on dental chairs. Core product lines include the Isolite Pro (illuminated, $2,209.95), Isolite Core and Core+ (non-illuminated, $1,049.95), patented single-use mouthpieces in six sizes (Pediatric through Large), the HOOPLA biodegradable retractor, the Operating Room Adapter (now biodegradable as of January 2025), and the Velop hypochlorous-acid disinfection system. The company is ISO 13485:2016 certified and manufactures domestically at its Santa Barbara facility.
Zyris serves general dentistry and pediatric dentistry practices as its primary use cases, with secondary segments in U.S. military and Veterans Affairs dental clinics (sold via GSA Contract V797P-3233N and ECAT Contract SPE2DE-17-D-0017), dental support organizations and group practices, and dental schools through the Dental Education Partnership Program (DEPP). The business model is a classic razor-and-blade construct: one-time hardware sales at the chair level seed a recurring consumables stream from proprietary single-use mouthpieces purchased per patient procedure, supplemented by an optional Isocare extended warranty and complementary products such as HOOPLA and Velop.
The company reaches customers through a multi-channel GTM: direct e-commerce via store.zyris.com, inside sales at 800-560-6066, demonstration-based selling with daily online demos and a 30-day money-back guarantee, and an international distributor network across 20+ countries (Henry Schein, Plandent, Anton Gerl, Yoshida Dental, Optident, MS-Dental, Verbiest Dental, and others). The company claims 80 million+ patients protected cumulatively, 2,600+ pediatric dentists using its system, and 100+ group practices as customers, and maintains a portfolio of dozens of industry awards dating back to 2002, including the DentalTown Townie Choice Award (2005-2018), IDEA Gold Award, and U.S. Air Force Dental Evaluation "Excellent" rating. Zyris remains wholly owned by its three co-founders — Sandra Hirsch (President and CEO), James A. Hirsch (co-founder and chief designer), and Thomas R. Hirsch, DDS (co-founder) — with no external private equity or venture capital disclosed.
Zyris firmographics
Firmographics- Name
- Zyris
- Legal name
- Zyris
- Website
- https://zyris.com
- Company type
- Private
- Founded year
- 2001
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- Zyris is a privately-held medical device company that designs, manufactures, and sells the Isolite dental isolation system, combining LED illumination, dual-channel suction, and retraction to serve general and pediatric dental practices, DSOs, and U.S. government dental clinics across 20+ countries.
- Ownership category
- akta.pro rank
Where Zyris is headquartered
LocationHeadquarters
- HQ city
- Goleta
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Zyris business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales
Revenue model
- Dental Isolation Hardware Systems: Sale of Isolite Pro, Isolite Core, and Isolite Core+ dental isolation systems. Isolite Pro includes integrated LED illumination while Core models offer suction-based isolation. Systems are durable goods with replacement/upgrade cycles.
- Single-Use Mouthpieces: Consumable revenue stream from proprietary single-use mouthpieces sold in packs. Available in 6 sizes for posterior and anterior procedures. Creates recurring revenue as practices purchase mouthpieces for each patient procedure.
- Extended Warranty (Isocare): Optional 2-year extended warranty beyond standard 1-year manufacturer warranty. No-fault coverage for repair or replacement. Available for purchase up to 6 months after initial system purchase.
- Government/VA Contracts: Sales to military and VA dental clinics through GSA/FSS/ECAT purchasing systems. Special government pricing with pre-determined contract terms including ECAT Contract SPE2DE-17-D-0017.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Pay-as-you-go | Isolite Pro - Premium illuminated isolation system |
| One time/ perpetual license | Pay-as-you-go | Isolite Core - Non-illuminated isolation system |
| Unit Pricing | Pay-as-you-go | HOOPLA Dental Retractor |
| Unit Pricing | Pay-as-you-go | Velop Operatory Sprayer |
| Other | Multi-year contract | International Distributor Pricing |
Go-to-market motion3 records
Distribution channels5 records
Marketing channels7 records
Zyris product offering
Product offeringCore offering
Zyris designs, manufactures, and sells the Isolite family of dental isolation systems, which combine LED illumination, dual-channel suction, soft tissue retraction, and a bite block in a single device. The company also produces patented single-use mouthpieces (anterior and posterior variants), the biodegradable HOOPLA dental retractor, an Operating Room Adapter, and the Velop operatory disinfection sprayer, serving dental practices, group practices, oral surgery centers, and government health facilities.
Product overview
Zyris offers a unified family of dental isolation products centered on the Isolite Systems, designed to provide comprehensive oral environment control. The core product line includes Isolite Pro (illuminated) and Isolite Core/Core+ (non-illuminated), both utilizing the same interchangeable single-use mouthpieces as the primary interface with patients. Supporting products include the HOOPLA biodegradable retractor and Operating Room Adapter (ORA) for specialized settings. The Velop disinfection system addresses practice hygiene. All systems are compatible with standard HVE dental equipment and can be purchased through online store, distributors, or government contracting vehicles including GSA/ECAT for military and VA facilities.
Differentiator
Problem solved
Functional benefit
Products and services
- Isolite Pro
- Isolite Core
- Isolite Core+
- Isolite Posterior Mouthpieces
- Isolite Anterior Mouthpieces
- HOOPLA Dental Retractor
- Operating Room Adapter (ORA)
- Velop Operatory Sprayer
- Isocare Extended Warranty
Quantifiable outcome
- Reduces sealant procedure time by 50%
- +8 more outcomes
Companies that use Zyris
Customer profileNamed customers11 records
Segments6 records
Ideal customer profiles4 records
Zyris technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration4 records
Feature7 records
Zyris partnerships and signals
Strategic signalScale indicators6 records
Recent moves1 record
Expansion highlights6 records
Zyris competitors and assessment
Company assessmentBroad incumbents
- A-dec: Privately-held dental equipment manufacturer specializing in dental chairs, delivery systems, and operatory equipment that physically integrates with Zyris Isolite systems via adapter kits.
- HuFriedyGroup: Dental instrument and infection-prevention manufacturer serving hygienists and restorative dentists with competing hand instruments, scalers, and isolation-adjacent consumables.
- Patterson Companies: Major U.S. dental and animal health distributor serving dental practices with equipment, supplies, and technology — overlapping customer base with Zyris and competing for chair-side workflow budgets.
- Henry Schein: Largest dental distributor in North America and a Zyris distribution partner across multiple countries; also distributes competing isolation and dental equipment lines, giving it significant channel and category influence.
- Dentsply Sirona: The world's largest dental equipment and technology manufacturer, offering delivery systems, imaging, CAD/CAM, and consumables that interface with — and increasingly compete with — Zyris's dental isolation and moisture-control category.
- Midmark: Dental equipment, sterilization, and operatory design manufacturer serving the same dental practice customer base with capital equipment purchases that compete for the same budget dollars as Zyris systems.
- Coltene: Swiss dental manufacturer offering restorative materials, endodontic instruments, and rubber dam systems — a competing approach to dental isolation/ moisture control versus Zyris's all-in-one isolation platform.
Direct peers
- Young Innovations: Manufacturer and distributor of dental preventive, restorative, and hygiene products sold through the same dental channels as Zyris, with overlapping customer relationships in general and pediatric dentistry.
- DryShield: DryShield manufactures an all-in-one dental isolation device combining suction, retraction, and bite block functionality — the most direct head-to-head competitor to Zyris's Isolite system, serving the same dental procedures and customer base.
Emerging players
- Premier Dental Products: Dental products manufacturer with a portfolio covering preventive, restorative, and endodontic categories — overlaps with Zyris in pediatric and restorative dentistry channels and is expanding in adjacent consumable categories.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
Zyris social profiles
Digital presenceZyris compliance and trust
Trust signalCompliance3 records
Zyris financial estimates
Financial estimateRevenue estimate
Valuation estimate
Zyris leadership team
Management profileNumber of profiles
Profiles9 records
Zyris funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Zyris M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Zyris
What does Zyris do?
Zyris designs, manufactures, and sells the Isolite family of dental isolation systems, which combine LED illumination, dual-channel suction, soft tissue retraction, and a bite block in a single device. The company also produces patented single-use mouthpieces (anterior and posterior variants), the biodegradable HOOPLA dental retractor, an Operating Room Adapter, and the Velop operatory disinfection sprayer, serving dental practices, group practices, oral surgery centers, and government health facilities.
Is Zyris a public or private company?
Zyris is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Zyris founded?
Zyris was founded in 2001. It employs 51 to 100 people.
Where is Zyris based?
Zyris is headquartered in Goleta, United States, in the North America region.
How does Zyris make money?
Four revenue lines are on record. Dental Isolation Hardware Systems are the primary driver. The others are single-Use Mouthpieces, extended Warranty (Isocare) and government/VA Contracts.
Who are Zyris's main competitors?
Broad incumbents on record are A-dec, HuFriedyGroup, Patterson Companies, Henry Schein, Dentsply Sirona, Midmark and Coltene. Direct peers are Young Innovations and DryShield. Premier Dental Products is listed as an emerging player.
Does Zyris have an API?
No public API is recorded for Zyris.