What Bio SB does

Bio SB, Inc. is a privately held biotechnology company founded in 2000 and headquartered in Goleta (Santa Barbara), California, that develops, manufactures, and distributes antibodies and detection systems for immunohistochemistry (IHC), immunocytochemistry (ICC), immunofluorescence (IF), chromogenic in situ hybridization (CISH), and fluorescent in situ hybridization (FISH) technologies. The company's product portfolio spans 500+ antibodies covering cancer diagnostics, infectious disease, and autoimmune applications, complemented by HRP/DAB detection systems (ImmunoDetector, PolyDetector, PolyDetector Plus), rapid immunohistochemistry solutions for Mohs surgery, tissue microarrays, substrate-chromogens, ancillary reagents, and automated equipment such as the TintoStainer Plus staining system. Bio SB manufactures under FDA QSR 21 CFR Part 820 cGMP, CE IVD, and ISO 13485:2016 certifications, meeting regulatory standards for in vitro diagnostic medical devices. The company distributes ZytoVision-brand FISH and CISH products and operates a VisionArray DNA chip platform for HPV and mycoplasma detection.

The company generates revenue primarily through one-time product sales of antibodies, detection kits, and equipment, sold either directly through its US e-commerce storefront (shop.biosb.com) or via a global distributor network covering 70+ countries across the Americas, Europe, Africa, Asia-Pacific, the Middle East, and Australia. Pricing is not publicly disclosed; customers must request quotes. Marketing is conducted through industry conferences (USCAP, AACR, ECP, SABCS), technical content resources, video tutorials, and social media. Bio SB's primary customer segments are hospital pathology departments and clinical diagnostic laboratories, academic and pharmaceutical research institutions, and specialized dermatopathology and Mohs surgery centers. The company has fewer than 50 employees and is independently operated with no disclosed external funding rounds, acquisitions, or institutional investor backing.

Name

Bio SB

Legal name

Bio SB, Inc.

Website

https://biosb.com

Company type

Private

Founded year

2000

Operating status

Operating

Headcount range

11–50 employees

Short description

Bio SB is a privately held Santa Barbara-based biotech that manufactures and distributes antibodies, detection systems, and automated staining equipment for immunohistochemistry, immunofluorescence, and in situ hybridization applications, serving clinical pathology laboratories, research institutions, and Mohs surgery centers across 70+ countries.

Ownership category

akta.pro rank

Product category

In Vitro Diagnostics (Immunohistochemistry Reagents and Equipment)

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413), Analytical Laboratory Instrument Manufacturing (334516)

SIC

In Vitro & In Vivo Diagnostic Substances (2835), Laboratory Analytical Instruments (3826)

akta.pro primary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

akta.pro secondary industries

Biomarker Assay & Reagent Development (LDT/IVD assay design, antibodies/standards/controls) (HLAAAMAL), Specialty & Biomarker Laboratory Services (Immunoassays/Flow/Cytometry) (HLAGAEAB)

Keywords

• Immunohistochemistry reagents
• Antibody detection systems
• In vitro diagnostics
• Fish cish probes
• Pathology laboratory equipment

Headquarters

HQ city

Goleta

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Supply Chain, Personnel, Technology or R&D, Marketing or Sales

Revenue model

1. Product Sales (Antibodies, Detection Systems, Equipment): Bio SB generates revenue through the direct sale of their manufactured products including antibodies, detection systems, substrate-chromogens, IHC ancillaries, and laboratory equipment such as the TintoStainer Plus automated staining system. Products are sold through their e-commerce storefront and global distributor network.
2. In Vitro Diagnostic (IVD) Products: Sale of IVD validated antibodies and detection kits that meet FDA QSR 21 CFR Part 820 cGMP, CE IVD and ISO13485:2016 certifications for clinical diagnostic use.
3. Research Use Only (RUO) Products: Sale of antibodies and reagents for research applications including tissue microarrays and equipment accessories.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels5 records

Core offering

Bio SB develops, manufactures, and distributes antibodies, detection systems, substrate-chromogens, IHC ancillaries, tissue microarrays, and laboratory equipment for immunohistochemistry (IHC), immunocytochemistry (ICC), immunofluorescence (IF), chromogenic in situ hybridization (CISH), and fluorescent in situ hybridization (FISH) applications. The company also distributes ZytoVision FISH and CISH probes and offers VisionArray DNA chip-based diagnostic products for HPV and mycoplasma detection, with all manufacturing conducted under FDA QSR 21 CFR Part 820 cGMP, CE IVD, and ISO 13485:2016 certifications.

Product overview

Bio SB is a manufacturer and developer of antibodies and detection systems for immunohistochemistry (IHC), immunocytochemistry (ICC), immunofluorescence (IF), chromogenic in situ hybridization (CISH), and fluorescent in situ hybridization (FISH) technologies. The company's product portfolio centers on its core antibody products (including rabbit monoclonal, mouse monoclonal, and IVD-validated antibodies) complemented by detection systems (ImmunoDetector, PolyDetector, PolyDetector Plus HRP), Fast Mohs IHC products for Mohs surgery, immunofluorescence products for autoimmunity testing, and ISH products (ZytoLight FISH, FlexISH, ZytoDot CISH, ZytoFast CISH). Supporting equipment includes the TintoStainer Plus automated stainer, TintoDetector and TintoDetector Mini capillary gap systems, and TintoRetriever pressure cooker. The company also offers VisionArray DNA chips for HPV and mycoplasma detection, along with tissue microarrays and consumables including substrate-chromogens and IHC ancillaries. Bio SB distributes ZytoVision brand FISH and CISH products and manufactures products under FDA QSR 21 CFR Part 820 cGMP, CE IVD, and ISO 13485:2016 certifications.

Differentiator

Problem solved

Functional benefit

Brands

• Bio SB Mexico: Regional distributor entity for Mexico market
• Cancer Diagnostics, Inc.

Products and services

• Antibodies for Immunohistochemistry Monoclonal and polyclonal antibodies (rabbit monoclonal, mouse monoclonal, and IVD validated) for IHC applications in cancer diagnostics, infectious disease, and research use.
• ImmunoDetector Detection Systems HRP/DAB based detection systems providing sensitive detection of antibodies in tissue samples for IHC applications.
• PolyDetector Micro-Polymer Detection Systems Biotin-free micro-polymer detection systems offering enhanced sensitivity and reduced background for IHC staining.
• PolyDetector Plus HRP Micro-Polymer Detection Systems Advanced HRP-based micro-polymer detection systems with superior sensitivity for automated and manual IHC workflows.
• Complete PolyDetector Kits Complete detection kits combining PolyDetector technology with necessary reagents for streamlined IHC workflows.
• Fast Mohs Immunohistochemistry Rapid IHC products and protocols designed for Mohs micrographic surgery, enabling same-day results for skin cancer margin assessment.
• Immunofluorescence Products Direct and indirect immunofluorescence products for autoimmunity testing and research applications.
• ZytoLight FISH Probes Fluorescent in situ hybridization (FISH) probes and kits for detection of chromosomal abnormalities and gene rearrangements in cancer diagnostics.
• FlexISH FISH Probes Flexible FISH testing solutions for standardized and reproducible detection of genetic alterations.
• ZytoDot CISH Products Chromogenic in situ hybridization (CISH) products for visualization of gene amplification and chromosomal changes using colorimetric detection.
• ZytoFast CISH Products Rapid chromogenic in situ hybridization products for accelerated gene detection workflows.
• VisionArray DNA Chip Diagnostics DNA chip-based detection systems including VisionArray HPV for human papillomavirus genotyping and VisionArray MYCO for mycoplasma detection.
• TintoStainer Plus Automated Staining System Fully automated IHC/ICC/IF instrument capable of deparaffinization, antigen retrieval, and staining. IVD medical device with 30-slide capacity, barcode identification, and walkaway operation for high-throughput laboratories.
• TintoDetector ImmunoDNA System Manual capillary gap system for IHC, ICC, CISH, and FISH applications providing consistent staining results.
• TintoDetector Mini Immuno System Compact capillary gap system for IHC, immunofluorescence, and ICC applications with smaller footprint for lower-throughput labs.
• TintoRetriever Pressure Cooker Pressure cooker for antigen retrieval in IHC workflows, enabling standardized heat-induced epitope retrieval.
• Tissue and Cell Line Microarrays Tissue microarrays including normal human tissue arrays, cancer human tissue arrays, cancer human cell line arrays, and infectious disease cell line arrays for quality control and research.
• Substrate-Chromogens Chromogenic substrates for visualization of IHC and ICC staining including DAB and other chromogen solutions.
• IHC Ancillaries Supporting reagents and ancillaries for IHC workflows including environment-friendly products, retrieval solutions, and blocking reagents.
• Multiplex Immunohistochemistry Detection System Detection system enabling simultaneous detection of multiple biomarkers on a single tissue section for advanced pathology research and diagnostics.
• SARS-CoV-2 / COVID-19 Antibodies IHC antibodies for SARS-CoV-2/COVID-19 immunohistochemistry applications to assess the pathogenesis of COVID-19.
• PRAME IVD Antibody PRAME antibody for immunohistochemistry applications in cancer diagnostics.
• 2021 New Products IHC Antibodies New IHC antibody products including Claudin-4, PRAME, and other biomarkers for cancer diagnostics.

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

One partnership is on record.

• ZytoVisioncoreChannel Partner/ Reseller/ DistributorBio SB distributes ZytoVision FISH and CISH products including ZytoLight probes, FlexISH, ZytoDot, and ZytoFast products for molecular diagnostics applications including HER2 testing, ALK/EML4 translocation detection, and other cancer biomarkers.

Scale indicators1 record

Recent moves6 records

Expansion highlights6 records

Direct peers

• Abcam: Abcam is a leading research-use antibody supplier with deep rabbit monoclonal catalogs; it overlaps directly with Bio SB's research antibody offering and increasingly competes in IHC-validated antibodies after its acquisition by Danaher.
• ZytoVision: ZytoVision is Bio SB's distribution partner and the original manufacturer of the ZytoLight FISH, FlexISH, ZytoDot CISH, and VisionArray HPV/MYCO product lines that Bio SB resells in molecular diagnostics.
• Novus Biologicals (Bio-Techne): Novus Biologicals, part of Bio-Techne, supplies a large catalog of IHC-validated antibodies and reagents to research and clinical labs — directly comparable to Bio SB's antibody and detection system portfolio.
• Epitomics (Abcam/Danaher): Epitomics specializes in rabbit monoclonal antibodies for IHC and was a pioneer in this technology; its product overlap with Bio SB's rabbit monoclonal antibody line makes it a close comparable in IHC primary antibodies.
• Cell Marque (MilliporeSigma): Cell Marque is an IHC-focused antibody and reagent manufacturer (now part of MilliporeSigma/Merck) with a similarly specialized catalog of pathology antibodies and detection reagents targeting hospital and reference-lab customers.

Broad incumbents

• Roche Diagnostics (Ventana): Roche's Ventana platform is the dominant clinical IHC system globally, bundling automated stainers with an extensive antibody menu that competes directly with Bio SB's IVD antibody and detection system portfolio.
• Bio-Rad Laboratories: Bio-Rad supplies life science research tools including IHC reagents, antibodies, and clinical diagnostics products, providing broader competition to Bio SB across both research and clinical pathology segments.
• Leica Biosystems: Leica Biosystems offers a full IHC/ISH platform including Bond staining systems, BOND antibodies, and detection reagents; competes with Bio SB across reagents and the TintoStainer Plus in the clinical pathology market.
• Agilent (Dako): Agilent's Dako pathology business offers IVD antibodies, HER2 FISH probes, and automated IHC platforms, overlapping with Bio SB's HER2/ALK biomarker reagents and IVD-validated antibody line.

Emerging players

• ACROBiosystems: ACROBiosystems is an emerging reagent supplier offering recombinant proteins and antibodies with growing IHC/diagnostics coverage; it competes for the same research and translational pathology customers that Bio SB serves.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/Bio_SB
• Facebookfacebook.com/BioSB
• Instagraminstagram.com/biosbinc

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Bio SB