Probiora Health

What Probiora Health does

Probiora Health, LLC is a privately held, women-owned oral health company headquartered in Sarasota, Florida, that develops, manufactures, and markets a family of oral probiotic supplements under the ProBiora® brand. The company's entire portfolio is powered by ProBiora3®, a patented blend of three mouth-native bacterial strains — Streptococcus uberis KJ2®, Streptococcus oralis KJ3®, and Streptococcus rattus JH145® — originally isolated by Dr. Jeffrey Hillman from healthy adult teeth and gums during 35+ years of research at the Harvard-affiliated Forsyth Institute and the University of Florida. Product SKUs include ProBiora (standard adult daily formula, 2.0 billion CFU), ProBiora Professional Strength (2.5 billion CFU, 90-count, extra-strength), ProBiora Kids (Orange Creamsicle flavor for children), and ProBiora for Pets (flavorless powder for dogs and cats), with clinical evidence supporting reductions in S. mutans, periodontal pathogens (C. rectus), bleeding on probing, and childhood caries incidence.

The business operates a dual go-to-market model: a direct-to-consumer e-commerce storefront at probiorahealth.com offering a Subscribe & Save subscription program (15% discount) alongside one-time purchases, and a professional dental channel serving registered practices through wholesale pricing, dedicated practice portals, Lunch & Learn education events, the EdNet hygienist consulting network, and case-of-12 bulk SKUs for in-office dispensing. Pricing spans $22.95 for a 30-count standard bottle to $64.95 for a 90-count professional bottle, with case pricing negotiated through the sales team. Revenue, funding history, and ownership structure beyond the executive team are not publicly disclosed; the company currently operates only in the United States within a global oral probiotic supplements market projected to reach $376.4 million by 2031 at a 7.5% CAGR.

Name

Probiora Health

Legal name

ProBiora Health, LLC

Website

https://probiorahealth.com

Company type

Private

Founded year

2009

Operating status

Operating

Headcount range

11–50 employees

Short description

Probiora Health is a privately held oral health company that develops and sells a family of probiotic supplements (ProBiora, ProBiora Kids, ProBiora Professional, ProBiora for Pets) powered by its patented three-strain ProBiora3® blend, serving US consumers and dental professionals through e-commerce subscription and professional wholesale channels.

Ownership category

akta.pro rank

Product category

Oral Probiotic Supplements

NAICS

Pharmaceutical Preparation Manufacturing (325412), Food (Health) Supplement Retailers (456191)

SIC

Perfumes, Cosmetics & Other Toilet Preparations (2844)

akta.pro industry

PRIMARYAFAKAJAH

Probiotic, Prebiotic & Gut-Health Foods Manufacturing (Fermented Functional Foods, Synbiotics)

Agriculture & Food Production/Food Processing & Manufacturing/Specialty & Functional Foods Manufacturing (Organic, Fortified, Medical Foods)

SECONDARYAFAJAJAE

Probiotics (Human & Animal Strains, Spore-Formers, Synbiotic Bases)

Agriculture & Food Production/Food Ingredients & Additives/Cultures & Fermentation Ingredients (Starter Cultures, Probiotics, Yeast)

SECONDARYCRADAGAF

Probiotics & Digestive Health Supplements

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/Vitamins, Supplements & Sports Nutrition

SECONDARYHLAMAHAH

Nutraceuticals & Functional Ingredients for Animal Diets (Probiotics, Omega-3, Joint, GI)

Healthcare & Life Sciences/Veterinary & Animal Health/Animal Nutrition & Therapeutic Diets

Keywords

• Oral probiotics
• Dental care supplements
• Oral microbiome products
• Pet dental probiotics
• Professional dental products

Headquarters

HQ city

Sarasota

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Marketing or Sales, Technology or R&D, Operations

Revenue model

1. Direct Product Sales - Consumer: E-commerce sales of ProBiora, ProBiora Kids, and ProBiora Pets products directly to consumers through the company website. Products sold in various sizes (30-count, 60-count bottles; single packets). Subscription model available with 15% discount for Subscribe & Save customers.
2. Professional/Dental Practice Sales: Wholesale and case sales of ProBiora Professional Strength to registered dental practices. Practices can purchase cases (12 bottles of 90-count) at wholesale pricing for in-office dispensing or patient recommendations. Professional channel includes dedicated practice portal for reordering.

Pricing tiers

Go-to-market motion3 records

Distribution channels3 records

Marketing channels7 records

Core offering

ProBiora Health develops, manufactures, and markets oral probiotic supplements powered by its patented ProBiora3® blend of three mouth-native bacterial strains (Streptococcus uberis KJ2®, Streptococcus oralis KJ3®, Streptococcus rattus JH145®). The company sells daily-use lozenges and pet powder formulations direct-to-consumer via e-commerce and through registered dental practices at wholesale pricing, targeting oral microbiome balance, gum health, fresher breath, cavity prevention, and natural tooth whitening for adults, children, and pets.

Product overview

Probiora Health offers a family of oral probiotic supplements designed specifically for the mouth, powered by their proprietary ProBiora3 patented probiotic blend containing three mouth-native bacterial strains. The product portfolio includes ProBiora (standard daily formula for adults in Mint or Orange), ProBiora Kids (Orange Creamsicle flavor for children), ProBiora Professional (extra-strength formula for dental professionals in Mint or Orange), and ProBiora for Pets (flavorless powder for dogs and cats). All products deliver beneficial bacteria directly to tooth surfaces and gum tissue to support oral microbiome balance, fresher breath, healthier gums, and whiter teeth.

Differentiator

Problem solved

Functional benefit

Products and services

• ProBiora Daily oral probiotic lozenge for adults delivering 2.0 billion CFU of the ProBiora3® blend in Mint or Orange flavor to support healthier teeth and gums, fresher breath, and naturally whiter teeth.
• ProBiora Kids Daily oral probiotic lozenge for children (ages 2+) in Orange Creamsicle flavor, delivering the ProBiora3® blend to support healthy developing teeth and gums and help prevent early childhood caries.
• ProBiora Professional Extra-strength oral probiotic lozenge delivering 2.5 billion CFU of the ProBiora3® blend in Gentle Mint or Orange flavors, targeted at dental professionals and adult consumers with periodontal or higher-risk oral health concerns.
• ProBiora for Pets Flavorless oral probiotic powder for dogs and cats sprinkled on food to deliver the ProBiora3® blend for fresher breath, reduced tartar, and healthier gums without the stress of brushing.
• ProBiora Professional Strength Case Bulk packaging of ProBiora Professional Strength in cases of 12 (90-count bottles), sold at wholesale pricing to registered dental practices for in-office dispensing or patient recommendation.
• ProBiora Kids Case

Quantifiable outcome

• 100% reduction in bleeding on probing in severe periodontal case after 12 months of use
• +5 more outcomes

Named customers6 records

Segments5 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Scale indicators6 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• NOW Foods (NOW Oral Health): Large supplement manufacturer offering an oral health probiotic (BLIS K12) among a broad nutritional portfolio. Competes in the same consumer probiotic supplement channel but with vastly greater scale and retail distribution than ProBiora.
• Colgate-Palmolive (Colgate Oral Care): Dominant oral care consumer goods company with toothpaste, mouthwash, and emerging oral probiotic partnerships. Represents the most threatening large-scale entrant ProBiora could face as the oral probiotic category matures.
• Arm & Hammer (Church & Dwight) Dental Care: Major mass-market oral care brand offering toothpaste and dental products with deep retail penetration. Adjacent competitor for the 'missing step' oral care routine narrative that ProBiora markets.
• Garden of Life (Dr. Perlmutter / Nestlé Health Science): Premium supplement brand with extensive probiotics portfolio including oral care probiotics. Comparable in product category and target consumer (health-conscious, ingredient-savvy) but vastly broader distribution through natural foods retail.
• Culturelle (i-Health): Major OTC probiotic brand (Lactobacillus rhamnosus GG) sold through mass retail and pharmacies. While primarily gut-focused, its distribution scale and brand recognition make it a likely future entrant into oral probiotics adjacent to ProBiora's positioning.
• Life Extension FLORASSIST Oral Hygiene: Established direct-to-consumer supplement brand with an oral probiotic SKU using BLIS strains. Targets similar health-conscious consumers via subscription and competes on the same oral microbiome thesis.

Emerging players

• Oragenics Inc. Original developer of the ProBiora3® strain technology through Dr. Jeffrey Hillman's research. Operates in adjacent oral microbiome/lantibiotic programs; former brand identity creates a direct technology and IP linkage with Probiora Health.
• PlaqueOff (Swedencare): Pet dental care brand (algae-based supplement for dogs and cats) addressing tartar, plaque, and bad breath. Direct competitor to ProBiora for Pets within the pet oral health supplement category.

Direct peers

• Hyperbiotics PRO-Dental: Direct competitor in the oral probiotic supplement category, offering probiotic tablets targeted at oral health including gum and teeth support through e-commerce and subscription. Comparable product format, target consumer, and category to ProBiora.
• BLIS Technologies (BLIS K12 / M18): New Zealand-based oral probiotic company whose Streptococcus salivarius K12 and M18 strains are widely licensed (NOW Foods, Life Extension). Direct technology and product competitor to ProBiora's mouth-native strains for oral and throat health.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Probiora Health