atSpiro

What atSpiro does

atSpiro is a privately held Danish laboratory-tools company, founded in 2019 and headquartered in Søborg, Denmark, that develops and sells the ShakeReactor — an automated, single-use bioreactor system designed to convert standard 500 mL or 1000 mL Erlenmeyer shake flasks into controlled fed-batch cultivation platforms. The company's core technology is a wireless, battery-powered module that snaps onto a standard shake flask and combines pre-sterilized pH and dissolved oxygen (DO) sensors with three programmable syringe-style pumps, enabling online monitoring of pH, DO, temperature, and humidity, plus automated controlled feeding, pH regulation, and induction. The system is complemented by the BioHub central controller, which manages communication across up to 26 parallel ShakeReactors via 4G or local network, streams data to atSpiro's cloud platform, and supports local-only deployments for closed-network environments. Software functionality includes custom recipe creation, automatic feeding profiles, pH control with configurable bounds, automatic induction scheduling, and CSV data export to Excel, MATLAB, or Python.

The company targets a horizontal set of upstream-bioprocessing customers: biopharmaceutical companies running clone selection, media and feed strategy comparison, and scale-up readiness testing; microbial fermentation labs (E. coli, Pichia pastoris, S. cerevisiae) doing strain selection and production-mimicking screening; CHO cell-culture teams requiring automated fed-batch feeding; and academic research institutions conducting bioprocessing education and early-stage process development. Named reference customers include Novozymes, Oxford Biotech (OXB), Swiftpharma, Copenhagen University (KU), and the Technical University of Denmark (DTU).

atSpiro's business model combines hardware sales (ShakeReactor units, BioHub controllers, and accessories) with a recurring revenue layer from pre-sterilized single-use sensor modules and dispensing containers that must be repurchased for each experiment, plus a cloud-platform subscription stream for remote monitoring and data management. The company sells exclusively through a direct enterprise sales motion — demo requests are routed through HubSpot scheduling, supported by a content-driven marketing funnel including a knowledge-hub blog, whitepaper downloads, and product datasheets. Pricing is quote-based and not publicly disclosed. Geographic footprint is described as global via direct sales, though only Europe is explicitly listed in operating geographies; the company has 1-10 employees, no disclosed funding rounds, no disclosed management team, no disclosed patents, and no disclosed partnerships.

Name

atSpiro

Legal name

atSpiro

Website

https://atspiro.com

Company type

Private

Founded year

2019

Operating status

Operating

Headcount range

1–10 employees

Short description

atSpiro is a Danish developer of the ShakeReactor, a wireless single-use bioreactor system that transforms standard 500 mL or 1000 mL shake flasks into controlled fed-batch cultivation platforms for biopharmaceutical, microbial fermentation, cell-culture, and academic research customers.

Ownership category

akta.pro rank

Product category

Bioprocessing Equipment

NAICS

Analytical Laboratory Instrument Manufacturing (334516), Automatic Environmental Control Manufacturing for Residential, Commercial, and Appliance Use (334512), Measuring, Dispensing, and Other Pumping Equipment Manufacturing (333914)

akta.pro primary industry

General Lab Equipment (Centrifuges, Incubators, Shakers, Ovens) (HLAGAIAC)

akta.pro secondary industry

Liquid Handling & Laboratory Automation (Pipettes, Robots, Workstations) (HLAGAIAD)

Keywords

• Single-use bioreactor
• Fed-batch fermentation
• Shake flask cultivation
• Bioprocess automation
• Microbial cultivation

Headquarters

HQ city

Søborg

HQ country

Denmark

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Supply Chain

Revenue model

1. ShakeReactor Hardware: Sale of ShakeReactor bioreactor systems including sensor modules, dispensing containers, BioHub controllers, and accessories. Hardware includes single-use components that require repurchase for each experiment.
2. Cloud Platform Services: Data management and remote monitoring services through atSpiro's cloud platform, with options for 4G connectivity or local network configuration.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels5 records

Core offering

atSpiro develops and sells the ShakeReactor, a wireless, battery-powered bioreactor system that clips onto standard 500 mL or 1000 mL Erlenmeyer shake flasks and adds online pH, dissolved oxygen, temperature, and humidity monitoring plus three programmable pumps for controlled feeding. The product enables automated fed-batch cultivation directly in shake flasks, paired with pre-sterilized single-use sensor modules, the BioHub central controller, and a cloud platform for remote monitoring. The offering is sold as hardware plus consumables to biopharma companies, biotech firms, and academic research institutions.

Product overview

atSpiro offers a single unified product platform centered on the ShakeReactor system, which transforms standard shake flasks into controlled, wireless bioreactors for fed-batch cultivation. The system comprises three integrated components: the ShakeReactor hardware (sensor and pump module that attaches to 500 mL or 1000 mL flasks), the BioHub connectivity hub for data management and multi-unit control, and the companion control software for experiment programming and remote monitoring. Together, they provide online monitoring of pH, dissolved oxygen, temperature, and humidity, along with automated feeding via three programmable pumps, enabling high-throughput fed-batch screening without the complexity of traditional bioreactors.

Differentiator

Problem solved

Functional benefit

Brands

• ShakeReactor: Wireless and battery-powered bioreactor system for standard shake flasks featuring monitoring of pH, dissolved oxygen, ambient humidity and temperature, with three programmable pumps for automated feeding and control.
• BioHub
• Sensor Module

Products and services

• ShakeReactor Wireless, battery-powered bioreactor system that attaches to standard 500 mL or 1000 mL Erlenmeyer shake flasks to enable fully monitored, automated fed-batch bioprocesses. Provides online pH, dissolved oxygen, temperature, and humidity monitoring, three programmable pumps for controlled feeding, and pH control with custom bounds. Sold to biotech and pharmaceutical companies, research institutions, and bioprocessing labs for clone selection, media and feed strategy comparison, seed train development, and scale-up readiness testing.
• BioHub Central hub that manages all communication with ShakeReactors and supports remote monitoring and control via 4G or local network. A single BioHub can connect to up to 26 ShakeReactor units in parallel and provides local storage equivalent to 12 ShakeReactors running continuously for 30 years. Sold to enterprise biopharma and academic research buyers as the connectivity backbone of the ShakeReactor system.

Quantifiable outcome

• Up to 857% higher protein yield compared to traditional shake flasks
• +5 more outcomes

Named customers5 records

Segments4 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Sartorius: Global leader in bioprocessing equipment and consumables, offering a full portfolio of benchtop and production-scale bioreactors directly competing with atSpiro's addressable workflow. Comparable as the dominant incumbent atSpiro must differentiate against.
• Cytiva (Danaher): Major bioprocessing supplier with Xuri cell expansion and single-use bioreactor systems serving biopharma. Overlaps with atSpiro in upstream bioprocessing but at much larger scale and broader portfolio.
• Thermo Fisher Scientific: Diversified life sciences giant with bioproduction equipment and consumables serving overlapping biopharma customers. Comparable as a broad incumbent whose benchtop bioreactor offerings sit in atSpiro's competitive set.

Direct peers

• Applikon Biotechnology (Getinge): Specialist bioreactor vendor (now part of Getinge) serving R&D through production bioprocess needs with benchtop and pilot systems. Closely comparable product category and customer base to atSpiro.
• Infors HT: Swiss manufacturer of lab-scale shakers and bioreactors (e.g., Minifors, Multifors). Directly competes with ShakeReactor in the early-stage microbial fermentation and cell culture R&D segment.
• PBS Biotech: Specialist in single-use, vertical-wheel bioreactors for cell and gene therapy applications. Comparable as a focused single-use bioreactor challenger targeting biopharma process development workflows similar to atSpiro's.
• Distek: US-based manufacturer of laboratory-scale bioreactors and dissolution instruments. Comparable as a niche vendor of benchtop bioreactors serving biopharma R&D and academic customers similar to atSpiro's.
• m2p-labs: Developer of micro-bioreactor platforms (BioLector) for high-throughput microbial cultivation and screening. Comparable as a specialist in miniature, high-throughput bioprocessing tools addressing the same screening use case as ShakeReactor.
• Solaris Biotech (Sartorius): Provider of stirred-tank single-use bioreactors for biopharma, now part of Sartorius. Comparable single-use, upstream bioprocessing focus relevant to atSpiro's consumable-driven model.
• Eppendorf: Manufacturer of benchtop bioreactors and shake-flask-based bioprocess tools (e.g., BioFlo, New Brunswick lines). Directly competes with ShakeReactor in the early-stage microbial and cell culture workflow atSpiro targets.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about atSpiro