What Halex Istar does

Halex Istar Ind\u00fastria Farmac\u00eautica S.A. is a Brazilian pharmaceutical manufacturer founded in 1959, headquartered in Goi\u00e2nia (Goi\u00e1s), specializing in ready-to-use injectable medications and parenteral solutions for the hospital channel. The company produces both large-volume and small-volume parenterals\u2014including saline, glucose, Ringer's lactate, metronidazole, ciprofloxacin, levofloxacin, tramadol, ondansetron, diclofenac, mannitol, and parenteral nutrition bags (PlasmaIstar, MixIstar, Istarhes)\u2014plus a flagship proprietary product, Halexminophen\u00ae, the only injectable paracetamol approved in Brazil (ANVISA 2020). All products are manufactured under ANVISA regulatory oversight, and the company holds multiple product registrations.

The company's operating footprint includes headquarters and main manufacturing in Goi\u00e2nia, a second manufacturing facility in Eus\u00e9bio (Cear\u00e1), a distribution center in S\u00e3o Paulo, and subsidiary Medicone (Cachoeirinha, RS) which exports to more than 20 countries. Halex Istar employs 5,001-10,000 people and sells through a direct sales-led model: a multi-state field representative network (covering at least 14 Brazilian states) targets hospitals, clinics, and healthcare institutions directly, supplemented by an SAC customer service channel (phone, WhatsApp, email). Ownership is family-controlled (founders Dr. Zanone Alves de Carvalho, Heno J\u00e1como Perillo, and Geraldo Rezende), with Carmen L\u00facia Perillo as Board President, Dr. Zanone as Founder and Board Chair, and Tiago Salinas as CEO.

Revenue is generated through one-time product sales of the hospital injectable portfolio to institutional buyers across Brazil and select international markets via Medicone. Pricing is not publicly disclosed and is handled through commercial quotes. Strategic R&D investment is supported by association with FINEP (Brazil's innovation financing agency). A 2016 funding round involved H.I.G. Capital. In 2025, Halex Istar partnered with Sindusfarma to donate approximately R$500,000 in medications to flood victims in Rio Grande do Sul, reinforcing its brand position within the Brazilian hospital ecosystem.

Name

Halex Istar

Legal name

Halex Istar Indústria Farmacêutica S.A.

Website

https://halexistar.com.br

Company type

Private

Founded year

1959

Operating status

Operating

Headcount range

5,001–10,000 employees

Short description

Halex Istar is a Brazilian pharmaceutical manufacturer of ready-to-use injectable medications and parenteral solutions, serving hospitals, clinics, and healthcare institutions across Brazil and exporting to more than 20 countries via its subsidiary Medicone.

Ownership category

akta.pro rank

Product category

Hospital Pharmaceuticals

SIC

Pharmaceutical Preparations (2834)

akta.pro primary industry

Pain Relief & Anti-Inflammatory (Analgesics) (HLAIADAA)

Keywords

• Parenteral solutions
• Injectable medications
• Hospital pharmaceuticals
• IV solutions
• Parenteral nutrition

Headquarters

HQ city

Goiânia

HQ country

Brazil

HQ region

Latin America

Offices4 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Personnel, Supply Chain, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Pharmaceutical Product Sales: Halex Istar develops, produces, and commercializes a broad portfolio of injectable medications and parenteral solutions, selling directly to hospitals, clinics, and healthcare institutions across Brazil. Revenue is generated through product sales across its full medication portfolio including analgesics, antibiotics, anti-inflammatories, and parenteral nutrition products.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels5 records

Core offering

Halex Istar develops, produces, and commercializes ready-to-use injectable medications and parenteral solutions (large and small volume) for the Brazilian hospital segment. Its portfolio spans analgesics (including the only injectable paracetamol in Brazil, Halexminophen®), antibiotics, anti-inflammatories, antiemetics, osmotic diuretics, neuromuscular blockers, and parenteral nutrition products — all ANVISA-registered and manufactured at facilities in Goiás and Ceará with distribution through a national field-sales network and a São Paulo distribution center.

Product overview

Halex Istar is a Brazilian pharmaceutical company specializing in hospital-grade injectable medications and parenteral solutions. The company operates a unified product portfolio centered on ready-to-use injectable pharmaceuticals including solutions (large and small volume parenterals), antibiotics, analgesics, and nutritional products. Key products include Halexminophen (the only injectable paracetamol in Brazil), various IV solutions (Ringer, glucose, saline), antibiotics (ciprofloxacin, levofloxacin, metronidazole), and specialty hospital products. The company also has a subsidiary, Medicone, which exports to over 20 countries. All products are ANVISA-registered and the company maintains facilities in Goiânia (headquarters), Eusébio (Ceará), and a distribution center in São Paulo.

Differentiator

Problem solved

Functional benefit

Brands

• Halexminophen: Injectable paracetamol product - the only injectable paracetamol available in Brazil, approved by ANVISA in 2020
• Halex Istar Solução Glicofisiológica
• Medicone
• MixIstar
• PlasmaIstar
• Istarhes

Products and services

• Halexminophen® (Injectable Paracetamol) Injectable paracetamol medication — the only paracetamol in injectable form available in Brazil. Approved by ANVISA in 2020, it is used for acute pain and fever treatment in hospital settings including post-operative, ICU, and emergency environments, and as a non-opioid alternative in multimodal pain management regimens.
• Large-Volume Parenteral Solutions (Saline, Glucose, Ringer's) Large-volume parenteral IV solutions including 0.9% Sodium Chloride (saline solution), Glucose Halex Istar (5% and other concentrations), Ringer solution, and Lactated Ringer's (containing sodium chloride, sodium lactate, potassium chloride, and calcium chloride) for fluid replacement and electrolyte correction in hospital settings. Halex Istar was the first industry to produce large-volume parenteral solutions in the state of Goiás.
• Small-Volume Parenteral Solutions Small-volume injectable pharmaceutical products in the Halex Istar and Isofarma lines, covering ciprofloxacin 2 mg/mL, fluconazole 2 mg/mL, levofloxacin 5 mg/mL, metronidazole 5 mg/mL, potassium chloride, potassium phosphate, calcium gluconate, magnesium sulfate, água para injeção (sterile water for injection), and other concentrated injectable formulations for hospital use.
• Injectable Antibiotics (Hidazol/Metronidazole, Ciprofloxacino, Levofloxacino) Injectable antibiotic portfolio including Hidazol (metronidazole) for anaerobic infections, Ciprofloxacino (fluoroquinolone) for bacterial infections, and Levofloxacino Hemi-Hidratado (fluoroquinolone) for respiratory and urinary tract infections, all ANVISA-registered for use in hospital settings.
• Injectable Analgesics and Anti-Inflammatories (Tramadol, Diclofenaco Sódico) Injectable analgesic and anti-inflammatory medications including Cloridrato de Tramadol (opioid analgesic for moderate to severe pain) and Diclofenaco Sódico (NSAID for pain and inflammation), intended for hospital use alongside Halexminophen® in multimodal pain management protocols.
• Parenteral Nutrition Products (Bolsa para Nutrição Parenteral, MixIstar, PlasmaIstar) Parenteral nutrition portfolio including Bolsa para Nutrição Parenteral Automática (automated parenteral nutrition bag for IV feeding), Bolsa para Nutrição Parenteral Gravitacional (gravity-fed parenteral nutrition bag for IV feeding), MixIstar (parenteral nutrition mixture product), and PlasmaIstar (plasma volume expander) for hospital nutritional support.
• Other Hospital Injectables (Ondansetrona, Manitol, ANMEIXIN/Rocurônio, Istarhes) Miscellaneous hospital injectable products including Cloridrato de Ondansetrona (antiemetic for prevention of nausea and vomiting), Manitol 20% (osmotic diuretic for reducing intracranial pressure), ANMEIXIN / Brometo de Rocurônio (neuromuscular blocking agent used as an adjunct to anesthesia), and Istarhes (hospital pharmaceutical product). Also encompasses the Glycophysiological solution (Halex Istar Solução Glicofisiológica).
• Medicone International Pharmaceutical Exports International export of pharmaceutical products through subsidiary Medicone Projetos e Soluções para a Indústria e a Saúde Ltda., located in Cachoeirinha, Rio Grande do Sul. Exports to more than 20 countries including Italy, Norway, Denmark, Sweden, and Chile, distributing Halex Istar Group injectable medications and parenteral solutions into international hospital markets.

Quantifiable outcome

• Halexminophen® offers 100% bioavailability via IV route, avoiding first-pass hepatic metabolism
• +1 more outcomes

Named customers1 record

Segments1 record

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature2 records

Partnerships

Three partnerships are on record, tiered core and minor.

• Sindusfarma (Sindicato da Indústria de Produtos Farmacêuticos)coreStrategic or Co-development PartnerHalex Istar partnered with Sindusfarma (Sindicato da Indústria de Produtos Farmacêuticos) to perform a solidarity action donating R$500,000 in medications (approximately 100,000 units) to the population of Rio Grande do Sul affected by floods. The donation included injectable paracetamol, antibiotics, anti-inflammatories, analgesics, glucose solutions, and sodium chloride solutions.
• FINEP (Financiadora de Estudos e Projetos)minorStrategic or Co-development PartnerHalex Istar is associated with FINEP (Financiadora de Estudos e Projetos), a Brazilian innovation agency, suggesting involvement in public funding or research and development support.
• Medicone Projetos e Soluções para a Indústria e a Saúde Ltda.coreOthersMedicone is a subsidiary of the Halex Istar Group. Located in Cachoeirinha (RS), Medicone manufactures pharmaceutical products and exports to over 20 countries including Italy, Norway, Denmark, Sweden, and Chile. The subsidiary was also affected by the Rio Grande do Sul floods and received internal support from Halex Istar.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• B. Braun: Global medical and pharmaceutical company specializing in IV solutions, infusion therapy, and clinical nutrition products. Highly comparable to Halex Istar in large- and small-volume parenteral solutions, with established presence in Brazil through its local subsidiary.
• EMS: Largest Brazilian pharmaceutical company by revenue, offering branded generics and hospital injectables including analgesics and IV solutions. Competes with Halex Istar in the Brazilian hospital channel but operates across a much broader portfolio including oral solids and OTC.
• Eurofarma: Major Brazilian pharmaceutical company with a substantial hospital injectables and specialty portfolio, including oncology and critical care products. Comparable to Halex Istar in serving Brazilian hospitals but with significantly broader therapeutic reach and international footprint.
• Biolab Farmacêutica: Brazilian pharmaceutical company with a strong hospital and specialty care presence. Overlaps with Halex Istar in Brazilian hospital injectables and IV solutions but extends further into cardiology, dermatology, and prescription brands.
• Baxter International: Global leader in IV solutions, parenteral nutrition, and injectable pharmaceuticals. While not a direct Brazil competitor, Baxter is the international reference point for Halex Istar's core parenteral solutions business and competes in adjacent Latin American markets.
• Fresenius Kabi: Global manufacturer of IV drugs, clinical nutrition, and medical devices for hospitals. Comparable to Halex Istar in parenteral nutrition (MixIstar, Bolsa para Nutrição Parenteral) and large-volume IV solutions, serving similar hospital customers worldwide.
• Aché Laboratórios: Brazilian pharmaceutical incumbent with a hospital division covering injectables, anti-infectives, and critical care products. Comparable in target customer (Brazilian hospitals) and product overlap with Halex Istar, though Aché has a more diversified branded-generic and consumer health portfolio.

Direct peers

• Cristália: Brazilian pharmaceutical manufacturer specialized in hospital injectables, anesthetics, and parenteral solutions—directly comparable to Halex Istar's portfolio of ready-to-use IV products and analgesics, serving the same SUS and private hospital channels in Brazil.
• Isofarma: Brazilian manufacturer of hospital injectables and parenteral solutions, including an overlapping product line with Halex Istar (note: 'Isofarma' products appear within Halex Istar's ANVISA registrations). Directly comparable in product mix and target customers within Brazilian hospitals.
• Hipolabor: Brazilian pharmaceutical manufacturer focused on generic injectables and hospital solutions, with similar manufacturing scale and customer base as Halex Istar. Directly competes in the same ready-to-use IV solutions and analgesic injectable categories within Brazil.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/halexistar
• LinkedInlinkedin.com/company/halexistar/posts/?feedView=all
• Instagraminstagram.com/halexistaroficial
• Xx.com/halexistarind

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Subsidiaries1 record

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Halex Istar