Promepla

What Promepla does

Promepla S.A.M. is a Monaco-headquartered contract design and manufacturing organization (CDMO) specializing in single-use plastic medical devices, operating for approximately 50 years. The company produces fluid management components, sterile-packaged assemblies, and custom-designed disposable devices, with a flagship Tuohy Borst Adapter line producing approximately 10,000 units per month. Its manufacturing footprint spans five production sites across Monaco, France (two locations including the acquired Medical Tubing facility at Le Bousquet d'Orb), Germany (A. Hopf GmbH in Cadolzburg, acquired 2022), Tunisia, and Morocco, with over 3,300 square meters of ISO 8 cleanroom capacity supporting injection molding, tubing extrusion, cleanroom assembly, sterilization, and packaging.

The company operates three revenue streams: contract manufacturing for medical device OEMs, OEM catalog component sales, and custom component development. It also acts as the exclusive European distributor for Nordson Medical and CPC components, generating a distribution-based revenue layer distinct from its own manufacturing. The customer base spans individual inventors to large multinational organizations across medtech and biopharma verticals, with named case-study customers including Physio-Assist, AMT (Applied Medical Technology), and an unnamed contract manufacturer client. Approximately 90 products hold CE Marking under the EU Medical Device Regulation (MDR) as of January 2025, with ISO 13485 certification and FDA compliance governing quality systems.

Promepla employs 400-500 staff across the group, is privately held with no external funding rounds disclosed, and appointed Jacques-Henry Grislain as CEO in October 2025 to lead the next growth phase. Recent strategic activity has centered on expanding capabilities through the 2022 acquisition of German injection molder A. Hopf and the 2023 acquisition of Medical Tubing in France, alongside a sustained product launch cadence (High-Flow Stopcocks, Twin Tubes, PVC-Free tubing, sustainable PVC alternatives, and DOTE-free components) targeting regulatory and environmental compliance demands.

Name

Promepla

Legal name

Promepla S.A.M.

Website

https://promepla.com

Company type

Private

Founded year

1975

Operating status

Operating

Headcount range

101–250 employees

Short description

Promepla is a Monaco-based contract design and manufacturing organization (CDMO) specializing in single-use plastic medical devices and fluid management components. It serves medical device OEMs, biopharma firms, and inventors across five production sites in Monaco, France, Germany, Tunisia, and Morocco.

Ownership category

akta.pro rank

Product category

Medical Device Contract Manufacturing (Single-Use Medical Device CDMO)

NAICS

Medical Equipment and Supplies Manufacturing (3391)

SIC

Gaskets, Packg & Sealg Devices & Rubber & Plastics Hose (3050)

akta.pro primary industry

Sterile Fill-Finish & Aseptic Manufacturing CDMO (HLAGABAH)

akta.pro secondary industry

Packaging, Labeling & Serialization (Clinical/Commercial) CDMO (HLAGABAJ)

Keywords

• Contract medical manufacturing
• Single-use medical devices
• Medical injection moulding
• Medical tubing extrusion
• Medical device sterilization

Headquarters

HQ city

Monaco

HQ country

Germany

HQ region

Europe

Offices6 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Supply Chain, Infrastructure, Technology or R&D, Marketing or Sales

Revenue model

1. Contract Manufacturing: Full-service contract design and manufacturing organization (CDMO) providing turnkey solutions for single-use medical devices from concept to commercialization.
2. Component Sales: Sale of standard OEM components including fluid management components, Luer fittings, check valves, connectors, stopcocks, Tuohy Borst adapters, tubing, and other single-use medical device components through component catalog.
3. Custom Component Development: Custom part development to exact specifications when existing components don't meet requirements, including slight modifications of existing items.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels4 records

Core offering

Promepla is a Contract Design and Manufacturing Organization (CDMO) for single-use plastic medical devices, providing integrated services from product design and prototyping through injection moulding, extrusion, cleanroom assembly, packaging, and sterilization (EO, Gamma, Beta, Autoclave). The company manufactures OEM components such as Tuohy Borst adapters, fluid management components, medical stopcocks, and medical tubing, and also serves as the exclusive European distributor of Nordson Medical and CPC components. Operations span five production sites in France, Germany, Tunisia, and Morocco with over 3,300 sqm of ISO Class 8 cleanroom space.

Product overview

Promepla is a contract design manufacturer for single-use plastic medical components and devices with nearly 50 years of experience. The company operates an integrated business model combining component manufacturing (fluid management components, tubing, stopcocks, adapters) with comprehensive contract manufacturing services. The product portfolio centers on Tuohy Borst Adapters as a best-selling device (~10,000 units/month), supported by Medical Tubing (extrusion operations in France) and A. Hopf (injection molding in Germany). Core services include product design & development, prototyping, testing, cleanroom manufacturing & assembly, packaging & labelling, sterilization (EO, Gamma, Beta, Auto Clave), and quality/regulatory affairs. The company also distributes specialized components through exclusive partnerships with CPC (quick disconnect couplings) and Nordson Medical (plastic connectors/tubing components). Manufacturing footprint spans Monaco (HQ), Signes France (production hub), Tunis Tunisia, Casablanca Morocco, Cadolzburg Germany (A. Hopf), and Le Bousquet d'Orb France (Medical Tubing), with over 3,500 sqm of ISO 8 cleanrooms across all sites.

Differentiator

Problem solved

Functional benefit

Brands

• A. Hopf: A. Hopf Kunststoffverarbeitung GmbH, part of Promepla Group, specialises in injection moulding for medical components. The company provides high-quality plastic solutions for the healthcare industry, with focus on BPA-free solutions.
• Medical Tubing

Products and services

• Contract Design and Manufacturing (CDMO Services)
• Tuohy Borst Adapters
• Fluid Management Components
• Medical Tubing
• A. Hopf Stopcocks
• A. Hopf Injection Molded Components
• Cleanroom Manufacturing & Assembly Services
• Sterilization Services
• Packaging and Labelling Services
• Quality Assurance & Regulatory Affairs Services
• Testing Services
• Product Design & Development Services
• Prototyping Services
• CPC Components Distribution
• Nordson Medical Components Distribution

Quantifiable outcome

• 20+ years of experience in manufacturing, assembly and packaging of single-use medical devices
• +2 more outcomes

Named customers3 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Five partnerships are on record, tiered core and minor.

• CPC – Colder Products CompanycoreChannel Partner/ Reseller/ Distributor · 1 November 2025Promepla is one of the few exclusive distributors of CPC components in Europe. CPC is a global leader in quick disconnect couplings, fittings, and connectors for life sciences sector. Promepla's Technical Product Manager Julien Jamet participates in CPC University events for technical training and to stay updated on latest innovations.
• Medical TubingcoreOEM/ Whitelabel/ Licensing Partner · 1 September 2023Medical Tubing, based in Le Bousquet d'Orb France, was acquired in 2023. With 30 years of experience in thermoplastic extrusion, it offers tubes of all sizes including multi-layer and multi-lumen options and PVC compounding services.
• A. Hopf GmbHcoreOEM/ Whitelabel/ Licensing Partner · 1 September 2022Acquired in 2022, A. Hopf Kunststoffverarbeitung GmbH is a family-owned German company specializing in plastic injection moulding for the life sciences sector. Founded in 1949, it serves all of Europe with high-quality injection moulded medical components from its Cadolzburg facility.
• Nordson MedicalcoreChannel Partner/ Reseller/ DistributorPromepla is one of few exclusive distributors of Nordson Medical components in Europe. Nordson Medical offers over 3,100 plastic tubing components including quick connect fittings, Luer fittings, and alternatives to Luer fittings for low pressure fluid management applications.
• Biopharmaceutical Partners (Switzerland & United States)minorStrategic or Co-development PartnerPromepla has partnerships with companies in Switzerland and the United States for biopharmaceutical production, involved in development of recombinant proteins, gene therapies, cell therapies, and viral vectors.

Scale indicators5 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• SMC Ltd: Medical device contract manufacturer with cleanroom assembly, injection moulding, and finished device manufacturing capabilities. Comparable scale and service model focused on single-use medical devices and OEM contract manufacturing.
• AdvantaPure (NewAge Industries): Manufacturer of high-purity tubing, fittings, and single-use systems for pharmaceutical and medical applications. Comparable in thermoplastic extrusion and single-use fluid management component manufacturing.
• Mack Group: Vertically integrated medical device contract manufacturer with injection moulding, assembly, packaging, and sterilization services. Comparable as a family-owned, multi-site CDMO serving medical device OEMs.
• Freudenberg Medical: Global medical device CDMO specializing in silicone and plastic components, catheter tubing, and finished devices with cleanroom manufacturing. Directly comparable as a vertically integrated single-use medical device contract manufacturer serving Medtech and Biopharma OEMs.
• Phillips-Medisize: Large medical device contract manufacturer offering drug delivery, medical device, and combination product development and manufacturing. Comparable as an integrated CDMO serving global medical device OEMs with injection moulding, assembly, and packaging capabilities.
• Flexan: Medical device contract manufacturer specializing in precision-molded components and sub-assemblies for medical and diagnostics applications. Comparable as a focused medical CDMO serving OEM customers.

Broad incumbents

• West Pharmaceutical Services: Global manufacturer of pharmaceutical packaging, injectable drug delivery, and medical device components. Overlaps with Promepla's fluid management and packaging components business but operates at much larger scale with broader product portfolio.
• Teleflex Medical OEM: Medical device contract manufacturing division offering extrusion, catheter fabrication, and finished device assembly. Comparable in extrusion capabilities and single-use medical device manufacturing focus.
• Jabil Healthcare: Large-scale contract manufacturer (formerly Nypro) serving medical device, pharmaceutical, and consumer health OEMs with injection moulding, cleanroom assembly, and packaging. Significantly larger than Promepla but directly competes for similar contract manufacturing programs.

Others

• Nordson Medical: Manufacturer of medical tubing components, fluid management fittings, and connection solutions - Promepla is one of its exclusive European distributors. Comparable in product technology (medical tubing/fluid management) and serves overlapping medical device OEM customers.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/Promepla-191195207728224
• LinkedInlinkedin.com/company/promepla

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Subsidiaries2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Promepla