Medspray
Medspray B.V. is a Dutch manufacturer of silicon microchip spray nozzle technology serving pharmaceutical, consumer health, and beauty brands with propellant-free, mono-disperse soft mist inhaler and spray device platforms.
- Company typePrivate
- Founded2002
- HeadquartersEnschede, Netherlands
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Medspray does
Medspray B.V. is a Dutch specialty manufacturer founded in 2002 and headquartered in Enschede, Netherlands, focused on silicon microchip-based spray nozzle technology for the pharmaceutical, consumer health, and beauty markets. The company's core technology consists of spray nozzle units (SNUs) fabricated from silicon wafers using lithography and etching techniques borrowed from semiconductor manufacturing, producing orifices of 1-30 micrometers that generate mono-disperse fine mist aerosols via the Rayleigh jet principle at production rates of approximately 2,400 SNUs per hour in ISO 8 cleanrooms. This engineering approach delivers quantitative performance advantages including 3-4x higher lung deposition versus conventional pressurized metered-dose and dry powder inhalers, greater than 50% lung dose of metered dose in the pre-filled syringe inhaler (PFSI) platform, 50x lower energy consumption than classical nebulizers, and roughly 10x less degradation of biological active ingredients during nebulization.
The product portfolio spans pharmaceutical soft mist inhalers (Ecomyst90, Soft Breezer, PFSI, Pulmospray), nasal delivery devices (Nasal Atomiser Adapter, multi-dose soft mist nasal spray), the Trachospray local anesthesia device for upper airway procedures, preservative-free ophthalmic sprays, and the Silk fine fragrance system. Six patent families protect the underlying technology and ISO 13485 certification has been maintained since 2010. The company is structured under five wholly-owned subsidiaries (Medspray Pharma B.V., Medspray Non-Pharma B.V., Medspray Technology & Manufacturing B.V., Medspray Anesthesia B.V., Medspray Mystic B.V.) plus a 49% stake in the Resyca joint venture with Recipharm (established 2020, EUR 15 million investment) which commercializes soft mist inhaler platforms for pharmaceutical and biologic customers.
Medspray operates a hybrid B2B revenue model combining direct sales of SNUs and custom device development services, an OEM/licensing model in which its nozzle technology is embedded inside partner-branded products such as Aptar Pharma's PureHale and Aptar Beauty & Home's Silk, and royalty/equity participation through the Resyca JV. Customers span pharmaceutical companies (prescription and OTC drug delivery), consumer health brands (nasal, eye, cough/cold, skin care), beauty and home care companies (fine fragrances and deodorants), medical device partners (respiratory humidification, anesthesia), and public health programs (Bill & Melinda Gates Foundation-funded nebulizer for premature infant respiratory distress syndrome). The company maintains enterprise sales through email and direct contact, with a 40-person operating team as of late 2023.
Medspray firmographics
Firmographics- Name
- Medspray
- Legal name
- Medspray B.V.
- Website
- https://medspray.com
- Company type
- Private
- Founded year
- 2002
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Medspray B.V. is a Dutch manufacturer of silicon microchip spray nozzle technology serving pharmaceutical, consumer health, and beauty brands with propellant-free, mono-disperse soft mist inhaler and spray device platforms.
- Ownership category
- akta.pro rank
Medspray industry classification
Industry- Product category
- Medical Device Components / Drug Delivery Technology
- NAICS
- Pharmaceutical Preparation Manufacturing (325412)
- SIC
- Pharmaceutical Preparations (2834)
- akta.pro primary industry
- Inhalers (MDI/DPI/SMI) (HLAHAIAI)
- akta.pro secondary industries
- Trigger Sprayers & Mist Sprayers (IMALALAE), Body Sprays & Mists (CRABADAC), Needle-Free Injection Systems (Jet Injectors/Microneedle Patches) (HLAHAIAD)
Keywords
Where Medspray is headquartered
LocationHeadquarters
- HQ city
- Enschede
- HQ country
- Netherlands
- HQ region
- Europe
Offices1 record
Markets served
Medspray business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Supply Chain, Operations, Infrastructure, Personnel, Marketing or Sales
Revenue model
- Spray Nozzle Unit (SNU) Sales: Manufacturing and selling spray nozzle units to pharmaceutical and consumer product companies. Units produced from silicon wafers in batch processes.
- Licensing of Technology: Licensing Medspray's patented spray nozzle technology to partners for integration into their products (e.g., Aptar for PureHale and Silk, Aero Pump for Ecomyst90).
- Custom Device Development: Developing customized inhaler and spray devices for specific pharmaceutical and consumer health applications, often in collaboration with partners.
- Resyca Joint Venture Revenue: Through 49% owned joint venture Resyca with Recipharm, generating revenue from pharmaceutical soft mist inhaler development and manufacturing.
Go-to-market motion3 records
Distribution channels5 records
Marketing channels6 records
Medspray product offering
Product offeringCore offering
Medspray designs and manufactures silicon-based micro- and nano-technology spray nozzle units (SNUs) that generate propellant-free mono-disperse fine mist sprays. The nozzles are produced from silicon wafers using lithography and etching techniques from semiconductor manufacturing, with orifice sizes of 1-30 micrometers. The company sells these nozzles and integrated soft mist inhaler, nasal, ocular, and fragrance delivery devices to pharmaceutical companies, consumer health brands, and beauty/home care manufacturers under OEM/embedded and licensing models.
Product overview
Medspray is a spray nozzle technology company offering a portfolio of soft mist inhaler devices and spray products across pharma, consumer health, and beauty sectors. The core technology consists of micro and nano-technology based spray nozzle units (SNUs) that create fine mist sprays without propellants. Key products include soft mist inhalers for respiratory conditions (Ecomyst90, Soft Breezer, PFSI inhaler, Pulmospray), nasal delivery devices (Nasal Atomiser Adapter, Nasal Spray), anesthesia devices (Trachospray), ophthalmic products (Eye Spray), and fragrance systems (Silk). The company also develops respiratory humidification technology. Medspray's nozzles produce mono-disperse droplets (4µm with 2µm hole) and are manufactured using silicon chip technology with orifices of 1-30 micrometers.
Differentiator
Problem solved
Functional benefit
Brands
- Resyca: Joint venture with Recipharm developing soft mist inhalers based on pre-filled syringes and Medspray's nozzle technology for pharma and biologic customers
- Trachospray
- Ecomyst90
- Silk
Quantifiable outcome
- Lung dose 3-4x larger than conventional pMDIs or dry powder inhalers
- +4 more outcomes
Companies that use Medspray
Customer profileNamed customers11 records
Segments3 records
Ideal customer profiles4 records
Medspray technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature8 records
Medspray partnerships and signals
Strategic signalPartnerships
19 partnerships are on record, tiered core, major and minor.
- RecipharmcoreJoint venture Resyca established with Recipharm investing EUR 15 million for 51% of shares. Medspray transfers softmist IP relating to pharmaceutical applications to Resyca. Resyca operates development facilities in Munich and manufacturing via Recipharm affiliates including King's Lynn, UK.
- ResycacoreJoint venture between Medspray and Recipharm combining spray nozzle technology with pharmaceutical device expertise. Medspray supplies nozzles exclusively to Resyca.
- Trachospray / Medspray AnesthesiacoreMedspray Anesthesia is a spin-off from Medspray, developing and supplying the Trachospray microdroplet spray device for local anesthesia. CE marked and available to medical professionals in EU.
- Aptar PharmamajorAptar Pharma's PureHale device uses Medspray's nozzle technology for upper airway condition relief products. PureHale uses Bag-on-Valve technology with compressed air.
- Aptar Beauty & HomemajorPartnership with Aptar Beauty & Home combining their dispensing systems knowledge with Medspray's spray technology to create Silk - ultimate refined fragrance spray.
- Aero PumpmajorJoint development of Ecomyst90 soft mist inhaler and Soft breezer device combining Aero Pump's pump system with Medspray's nozzle technology.
- Radboud University Medical CentermajorClinical partnership for Trachospray development. Prof. dr Jörgen Bruhn and dr. Geert-Jan van Geffen invented the concept. Radboud umc ran clinical trials validating safety and efficacy.
- Surterra WellnessmajorSurterra Wellness distributes Ecomyst90 CBD inhaler in US market. Their subsidiary Molecular Infusions developed the CBD formulation optimized for Medspray's soft mist inhaler device.
- ResycacoreDaughter company Resyca supplied Pulmospray soft mist inhalation devices for Phase IIb clinical trial of COVID-19 induced hypoxemia treatment with low molecular weight Heparin.
- PCV GroupmajorPartnership to develop innovative active humidifier controlling absolute humidity instead of relative humidity for improved respiratory care and medication delivery efficiency.
- UnitronmajorPartnership with PCV Group and Unitron to develop active humidifier technology for respiratory care with focus on absolute humidity control.
- ProfTechminorVIVA project partner alongside Medspray and Saxion University developing image-driven inspection system for micro-fluidic chip assembly quality control.
- Saxion University of Applied SciencesminorVIVA project partner alongside Medspray and ProfTech developing image-driven inspection system for micro-fluidic chip assembly quality control.
- AmferiaminorEurostars Grant collaboration for development of antimicrobial spray for wound care using Amferia's antimicrobial peptide-hydrogel materials with Medspray's spray technology.
- Silo PharmamajorExclusive license agreement for Medspray's soft mist nasal spray technology for use with SPC-15 therapeutic drug for PTSD, anxiety, Alzheimer's disease, and anorexia treatment.
- Royal Netherlands Aerospace Centre (NLR)minorProvided expertise and equipment for COVID-19 research on aerosol spreading behavior in airplane cabins.
- Dutch National Institute for Public Health and the Environment (RIVM)minorCollaborated on COVID-19 aerosol research validating models for infection risk during airplane flights.
- Twente UniversityminorR&D operations conducted at extensive Nanolab facilities of Twente University where operators create silicon nozzle chips for research purposes.
- Seattle Children's HospitalminorPrototypes being tested at Seattle Children's Hospital to validate nebulization technique for liquid surfactants for premature infant treatment.
Scale indicators13 records
Recent moves7 records
Expansion highlights6 records
Medspray competitors and assessment
Company assessmentDirect peers
- Vectura Group (Kindeva Drug Delivery): Inhalation drug delivery specialist developing DPI and pMDI platforms for pharma partners. Operates in overlapping soft mist and propellant-free inhaler licensing territory where Medspray competes.
- Aptar Pharma: Global drug delivery device company serving pharma and consumer health. Directly comparable because Aptar Pharma partners with Medspray to embed its nozzle chip in PureHale and Silk devices, competing in pMDI, soft mist, nasal, and topical spray platforms.
- Recipharm: Pharmaceutical contract development and manufacturing organization. Recipharm co-owns the Resyca JV with Medspray (51%/49%) for soft mist inhaler development and fill-finish services, operating in the same pharmaceutical device and inhalation therapy value chain.
- Aero Pump: German specialty pump and inhaler manufacturer. Aero Pump combines its pump systems with Medspray's nozzle technology in Ecomyst90 and Soft Breezer soft mist inhalers, directly competing in propellant-free multi-dose inhalers.
- Nemera: Drug delivery device company specializing in inhalers, nasal, ophthalmic, and parenteral devices. Nemera competes directly in soft mist and nasal spray device platforms with equivalent regulatory and OEM partnerships.
- PARI Pharma: Manufacturer of nebulizers and inhalation drug delivery systems. PARI's eFlow and LC Sprint jet nebulizers compete with Medspray's Pulmospray and PFSI platforms for pulmonary drug delivery, particularly in hospital and home-care settings.
- Resyca: Joint venture between Medspray (49%) and Recipharm (51%) developing soft mist inhalers based on pre-filled syringes. Medspray supplies nozzle technology exclusively to Resyca, creating an internal commercial arm that competes with established inhaler CDMOs.
Emerging players
- HCmed Innovations: Taipei-based developer of mesh nebulizer and portable drug delivery technology. Competes in portable inhalation drug delivery with its own MEMS-driven mesh nebulizer platform overlapping with Medspray's soft mist inhaler use cases.
Broad incumbents
- Gerresheimer: Global manufacturer of pharmaceutical primary packaging including glass syringes, plastic containers and inhaler components. Provides adjacent drug delivery components relevant to Medspray's PFSI pre-filled syringe inhaler platform.
- Stevanato Group: Provider of drug containment and delivery solutions including pre-filled syringes and device integration. Its pharma device platform competes in adjacent delivery systems relevant to Medspray's syringe-based inhaler.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights6 records
Customer concentration
Medspray social profiles
Digital presenceMedspray compliance and trust
Trust signalCompliance3 records
Medspray financial estimates
Financial estimateRevenue estimate
Valuation estimate
Medspray leadership team
Management profileNumber of profiles
Profiles3 records
Medspray subsidiaries and ownership
Company hierarchySubsidiaries6 records
Medspray funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Medspray M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Medspray
What does Medspray do?
Medspray designs and manufactures silicon-based micro- and nano-technology spray nozzle units (SNUs) that generate propellant-free mono-disperse fine mist sprays. The nozzles are produced from silicon wafers using lithography and etching techniques from semiconductor manufacturing, with orifice sizes of 1-30 micrometers. The company sells these nozzles and integrated soft mist inhaler, nasal, ocular, and fragrance delivery devices to pharmaceutical companies, consumer health brands, and beauty/home care manufacturers under OEM/embedded and licensing models.
Is Medspray a public or private company?
Medspray is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Medspray founded?
Medspray was founded in 2002. It employs 11 to 50 people.
Where is Medspray based?
Medspray is headquartered in Enschede, Netherlands, in the Europe region.
How does Medspray make money?
Four revenue lines are on record. Spray Nozzle Unit (SNU) Sales are the primary driver. The others are licensing of Technology, custom Device Development and resyca Joint Venture Revenue.
Who are Medspray's main competitors?
Direct peers on record are Vectura Group (Kindeva Drug Delivery), Aptar Pharma, Recipharm, Aero Pump, Nemera, PARI Pharma and Resyca. HCmed Innovations is listed as an emerging player. Broad incumbents are Gerresheimer and Stevanato Group.
Does Medspray have an API?
No public API is recorded for Medspray.
What industry is Medspray in?
Medspray's product category is Medical Device Components / Drug Delivery Technology. Its primary akta.pro industry code is HLAHAIAI, Inhalers (MDI/DPI/SMI), with a secondary code of IMALALAE, Trigger Sprayers & Mist Sprayers. Its NAICS code is 325412 and its SIC code is 2834.