What Bioinicia does

Bioinicia is a Spanish technology company founded in 2012 as a spin-off from CSIC (Consejo Superior de Investigaciones Científicas) and headquartered in a 6,800 sqm facility in Paterna, Valencia. It specializes in electro-hydrodynamic (EHD) processing, encompassing electrospinning and electrospraying, to produce nano- and micro-structured fibers and particles for pharmaceutical, cosmetic, nutraceutical, and filtration applications. Core technology platforms include the Fluidnatek® and Spinbox® electrospinning equipment lines (from benchtop LE-50 and Spinbox units to pilot-scale LE-500), the patented Capsultek® EAPG microencapsulation process (developed with IATA-CSIC), the PROVEIL® nanofiber filtration media (co-developed with CSIC), the Rivelin® mucoadhesive drug delivery patch (manufactured for Dermtreat A/S), and the Fiber Boost technology underpinning the Bioinicia Cosmetics consumer line. The company was the world's first electrospinning contract manufacturer to receive GMP certification (2017) and ISO 13485 certification (2018) for nanofiber medical device production.

Bioinicia generates revenue across five streams: contract R&D and process scale-up services for pharma/cosmetic/nutraceutical clients, GMP-certified contract manufacturing of electrospun fibers and electrosprayed particles, direct and channel-partner sales of Fluidnatek® and Spinbox® equipment (with distribution partners in the US, China, and Mexico), DTC sales of PROVEIL® branded protective masks via proveil.es, and branded consumer cosmetic products under Bioinicia Cosmetics. Capacity stands at 10 tons/year of fibers, 20 tons/year of dry particles, and 30 tons/year of nanofiber filter media. Industrial-scale GMP manufacturing of pharmaceutical products is concentrated at the Valencia site, where the company also operates an ISO 7 Class D cleanroom.

The business is funded almost entirely through non-dilutive public grants (cumulative EU and regional awards exceeding €8M, including H2020 SME Instrument Phase II, Horizon Europe REBORN, and EU4Health 2G-PROVEIL), with no private equity or venture capital rounds documented. Customers span university research labs, materials SMEs, big pharma (Janssen), biotech (Dermtreat A/S), air purification (Zonair3D), and consumer segments. Leadership is anchored by founder José María Lagarón (IATA-CSIC researcher) and co-founder/CEO Lars Markwort, supported by a small team of project managers and product specialists.

Name

Bioinicia

Legal name

BIOINICIA SL

Website

https://bioinicia.com

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

11–50 employees

Short description

Bioinicia is a Spanish CSIC spin-off providing contract R&D, GMP-certified manufacturing, and electrospinning/electrospraying equipment to pharmaceutical, cosmetic, nutraceutical, and filtration customers, supplemented by PROVEIL® mask and Bioinicia Cosmetics branded consumer products.

Ownership category

akta.pro rank

Headquarters

HQ city

Paterna

HQ country

Spain

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Operations, Infrastructure, Supply Chain

Revenue model

1. Contract R&D and Development Services: Bioinicia provides contract research and development services to pharmaceutical, cosmetic, nutraceutical, and biomedical companies for developing micro- and nano-fiber-based products, functional coatings, and encapsulation solutions. Services span from concept feasibility through process scale-up.
2. Contract Manufacturing (GMP-certified): Bioinicia offers outsourced industrial manufacturing of electrospun fibers and electrosprayed micro/nanoparticles under GMP (pharma) and ISO 13485 (medical devices) certifications. Specializes in pharmaceuticals and nutraceuticals. Annual production capacity of 10 tons of fibers, 20 tons of dry particles, and 30 tons of nanofiber filter media.
3. Electrospinning & Electrospraying Equipment Sales: Sale of Fluidnatek® and Spinbox® branded electrospinning and electrospraying equipment — from benchtop lab machines to pilot and industrial scale — to research institutions, universities, and industrial companies. Equipment is sold directly and through channel partners in the US, China, Mexico, and Canada.
4. PROVEIL® Filter Media and Consumer Masks: Sale of PROVEIL® nanofiber filter media and finished products including protective masks (PROVEIL® BIOMASK biodegradable mask, PROVEIL® KIDS) through e-commerce (proveil.es) and potentially retail channels.
5. Bioinicia Cosmetics Consumer Products: Sale of consumer cosmetic products (3 Seconds Patch and related products) under the Bioinicia Cosmetics brand, marketed as 'pure cosmetics' — 100% bio-active ingredients with no preservatives or excipients.

Go-to-market motion3 records

Distribution channels3 records

Marketing channels6 records

Core offering

Bioinicia provides contract development and GMP-certified contract manufacturing of electrospun fibers and electrosprayed nano/microparticles for pharmaceutical, cosmetic, nutraceutical, and biomedical applications, using proprietary electro-hydrodynamic (EHD) processing. The company also designs, produces, and sells its own brand of electrospinning and electrospraying equipment (Fluidnatek® and Spinbox®) for lab, pilot, and industrial scale. Consumer-facing product lines include PROVEIL® nanofiber protective masks and Bioinicia Cosmetics' 3 Seconds Patch.

Product overview

Bioinicia is a technology-based company and CSIC spin-off offering electrospinning and electrospraying equipment under the Fluidnatek® and Spinbox® brands, along with GMP-certified contract manufacturing services. The product portfolio includes laboratory-scale equipment (Spinbox, LE-50), advanced R&D systems (LE-100), and pilot/industrial production machines (LE-500). The company also manufactures finished products including PROVEIL® nanofiber filtration media for protective masks, the Rivelin® mucoadhesive drug delivery patch, and Bioinicia Cosmetics products like the 3 Seconds Patch. Key technology platforms include Capsultek® EAPG microencapsulation and Fiber Yarn devices. Services span R&D development, process engineering, and industrial manufacturing across pharmaceuticals, cosmetics, nutraceuticals, and filtration applications.

Differentiator

Problem solved

Functional benefit

Brands

• Fluidnatek: Premium electrospinning and electrospraying equipment for laboratory to industrial-scale processing, including LE-50, LE-100, and LE-500 models.
• Spinbox
• PROVEIL
• Capsultek
• Bioinicia Cosmetics
• Rivelin

Products and services

• Fluidnatek LE-50 Compact laboratory benchtop electrospinning and electrospraying machine positioned as a powerful advanced research station. Features modular configuration for electrospinning or electrospraying tasks, compatibility with AC unit for climate control, touch-control interface with data logging and multi-user level access, CE certification, and UL compatibility.
• Fluidnatek LE-100 Advanced R&D electrospinning machine for projects that require flexibility. Features a large experimental chamber, a wide range of optional features, up to 20 emitters for increased productivity, programmable X/Y/Z axes motion for patterned deposition, and optional climate control via AC unit.
• Fluidnatek LE-500 Pilot-line production tool for developing products from initial concept to pilot-scale manufacture. Features roll-to-roll collection, large-volume solution reservoirs, high-throughput multi-emitter spinning heads, and dual operating modes (R&D mode and manufacturing mode).
• Spinbox Modular benchtop electrospinning and electrospraying instrument for lab-scale fabrication of micro- or nano-structured fibers and particles. Entry-level system with simple, user-friendly design for quick experimental set-up, suitable for teaching purposes and proof-of-concept activities.
• PROVEIL Mask Line Nanofiber filtration mask line featuring non-electrostatic mechanical filtration that maintains >98% bacterial filtration efficiency over extended use. The line includes PROVEIL® (adult), PROVEIL® KIDS (ages 6–9), PROVEIL® BIO/BIOMASK (compostable, FFP2-like filtration), and a transparent hygienic mask for lip-reading accessibility. Sold via proveil.es and through distribution partners.
• Rivelin Patch Dual-layer electrospun mucoadhesive patch for oral mucosal drug delivery developed with Dermtreat A/S. One layer is drug-loaded and bio-adhesive (hydrophilic, facing mucosa); the other is a barrier layer (hydrophobic, non-adhesive, facing the mouth) enabling unidirectional drug delivery. Targeted at indications such as Oral Lichen Planus, with extended-release, occlusion for pain relief, and improved patient compliance compared to off-label creams or mouthwashes.
• 3 Seconds Patch (Bioinicia Cosmetics) Cosmetic patch product composed 100% by active ingredients. Uses electro-hydrodynamic Fiber Boost technology that increases active penetration by more than ten times compared to conventional liquid formulations. Fibers are 100× finer than human hair and dissolve instantly on skin contact, producing a cosmetic effect within 3 seconds of application.
• Capsultek EAPG Microencapsulation Platform High-throughput microencapsulation technology platform combining high voltage and pneumatic pressure for room-temperature single-step encapsulation. Produces free-flowing powder with particle sizes 1–10 µm and adjustable bulk density (90–600 kg/m³), ideally suited for thermo-sensitive bioactives including probiotics, peptides, and omega-3.
• Contract R&D and Process Development Services Contract research and development services covering micro- and nano-fiber-based products, functional coatings, and encapsulation solutions for pharmaceutical, cosmetic, nutraceutical, and biomedical clients — from concept feasibility through process scale-up.
• Contract Manufacturing (GMP-certified) Outsourced industrial manufacturing of electrospun fibers and electrosprayed micro/nanoparticles under GMP (pharmaceutical) and ISO 13485 (medical devices) certifications. Specialises in pharmaceuticals and nutraceuticals, with annual production capacity of 10 tons of fibers, 20 tons of dry particles, and 30 tons of nanofiber filter media.

Quantifiable outcome

• Nanonized valsartan showed a 4.7× increase in systemic exposure (bioavailability) compared with pure API in Bioinicia's nano-in-micro (nano-in-micro) platform.
• +6 more outcomes

Named customers7 records

Segments5 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Scale indicators11 records

Recent moves12 records

Expansion highlights6 records

Broad incumbents

• Corbion: Dutch global leader in bio-based food ingredients and biochemicals including bioactives and encapsulation. Comparable to Bioinicia's nutraceutical encapsulation business but at much larger scale and broader portfolio.
• DSM Biomedical: Royal DSM's biomedical materials business offers bioresorbable polymers and drug delivery platforms to medical device and pharma customers. Comparable in GMP-grade biomaterials manufacturing for drug delivery applications.
• Evonik Health Care: Global specialty chemicals company's health care division provides CDMO services for pharmaceutical excipients, APIs, and drug delivery systems. Broad incumbent comparable to Bioinicia's pharma manufacturing capabilities at far larger scale.

Direct peers

• Inovenso: Turkey-based electrospinning and electrospraying equipment manufacturer offering lab-to-industrial-scale systems. Directly competes with Fluidnatek in the electrospinning equipment market.
• Nanofiber Solutions: US-based company specializing in electrospun nanofiber scaffolds for 3D cell culture and tissue engineering applications. Comparable in biomedical nanofiber manufacturing with pharmaceutical/biotech customer base.
• The Electrospinning Company: UK-based specialist in electrospun materials for medical devices, drug delivery, and regenerative medicine, offering contract manufacturing and consulting. Closely comparable to Bioinicia as a specialized electrospinning CDMO with biomedical focus.
• Elmarco: Czech-based manufacturer of industrial-scale electrospinning equipment (Nanospider) for filtration, energy, and biomedical applications. Direct peer to Bioinicia in equipment manufacturing for nanofiber production.
• Yflow: Spanish electrospinning equipment manufacturer offering laboratory and industrial systems. Geographic and product peer, serving similar academic and industrial research customers.
• Finetex EnE: Korean manufacturer of electrospinning equipment and nanofiber products for filtration, energy, and biomedical markets. Direct competitor in industrial-scale nanofiber production equipment.

Emerging players

• Bio-On: Italian bioplastics company developing PHA-based biodegradable materials for packaging and specialty applications. Comparable in biodegradable materials and bio-based product development focus.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/bioinicia-s-l-
• Xx.com/bioinicia
• Facebookfacebook.com/BioiniciaFluidnatek

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Subsidiaries2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Bioinicia