What Syntellix does

Syntellix AG is a Hannover, Germany-based medical device company founded in 2008 that develops and commercializes MAGNEZIX®, a biotransformable magnesium alloy platform used to manufacture orthopedic and trauma implants. The MAGNEZIX® material is engineered to provide metallic stability comparable to titanium while being progressively resorbed by the body and converted into bone tissue, eliminating the need for a second removal surgery, exhibiting osteoconductive and infection-inhibiting properties, and offering mechanical elasticity closer to human bone than conventional metal implants. Syntellix holds the world's first CE marking for a biotransformable metallic implant (granted 2013) and an HSA approval in Singapore, and is the registered holder of the MAGNEZIX® and StarFuse® trademarks plus patents covering alloy composition and implant design.

The product portfolio comprises CS compression screws (2.0–4.8 mm, cannulated and self-tapping variants), Pins in 1.5–3.2 mm sizes with mechanical stability reported at 5x PLA/PGA polymers, CBS cortical bone screws with a patented safety-drive design, StarFuse® implants for PIP toe joint fusion, and IFSc interference screws for cruciate ligament reconstruction. Syntellix produces exclusively in Germany under a "Made in Germany" positioning and sells through authorized distribution partners covering the D/A/CH region and worldwide markets spanning more than 30 countries. A wholly-owned subsidiary, Syntellix Asia Pte Ltd, manages Asia-Pacific operations from Singapore. End customers are orthopedic and trauma surgeons, sports-medicine physicians, the hospitals and orthopedic practices they work in, and—explicitly targeted—healthcare cost-bearers (Kostenträger). The company is led by Prof. Dr. Utz Claassen (CEO/Vorstand) with Annette Claassen chairing the Supervisory Board and Dr.-Ing. Jan-Marten Seitz on the Board; in 2019 Syntellix acquired Materials Science and Engineering Werkstoffzentrum Clausthal to consolidate metallurgical R&D.

Revenue is generated through B2B hardware sales of implants to hospitals and orthopedic practices via distribution partners, with pricing negotiated per volume and contract in standard med-device fashion; specific pricing is not publicly disclosed. Marketing combines a tri-audience website (doctor / patient / cost-bearer portals), LinkedIn and YouTube channels, newsletter, and conference presence. Syntellix is privately held, has not publicly disclosed funding rounds or revenue figures, and has been recognized with the German Industry Innovation Prize (2013), consecutive Top-Innovator awards (2015, 2016), the German Healthcare Future Prize (2016), the STEP Award TECH (2017), the German Medical Award (2017), and Innovator of the Year (2017).

Name

Syntellix

Legal name

Syntellix AG

Website

https://syntellix.de

Company type

Private

Founded year

2008

Operating status

Operating

Headcount range

51–100 employees

Short description

Syntellix AG develops and sells CE-marked MAGNEZIX® biotransformable magnesium-alloy orthopedic and trauma implants (screws, pins, StarFuse®, IFSc) to hospitals and orthopedic practices in 30+ countries via distribution partners and a Singapore subsidiary.

Ownership category

akta.pro rank

Product category

Orthopedic Medical Devices

NAICS

Surgical Appliance and Supplies Manufacturing (339113), Surgical and Medical Instrument Manufacturing (339112)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842)

akta.pro primary industry

Orthopedic Trauma & Extremities Fixation (Plates/Screws/Nails/External Fixation) (HLAHAEAB)

Keywords

• Bioresorbable orthopedic implants
• Magnesium alloy implants
• Bone fixation devices
• Medical device manufacturing
• Trauma surgery implants

Headquarters

HQ city

Hanover

HQ country

Germany

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Operations, Supply Chain, Personnel, Marketing or Sales, Others

Revenue model

1. Medical Device Sales: Syntellix generates revenue through the sale of its MAGNEZIX® biotransformable implant products including CS screws, pins, CBS screws, StarFuse®, and IFSc. Sales are conducted through authorized distribution partners to hospitals and orthopedic practices globally. Products are sold B2B with pricing based on product type and volume.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels5 records

Core offering

Syntellix AG develops, manufactures, and distributes MAGNEZIX® — a proprietary biotransformable magnesium alloy material used to fabricate orthopedic and trauma implants (compression screws, bone pins, cortical bone screws, StarFuse® toe-joint fusion implants, and IFSc interference screws). The implants offer metallic stability similar to titanium while being gradually resorbed and transformed by the body into bone tissue, eliminating the need for second-removal surgery. Products are CE-marked in Europe, HSA-approved in Singapore, and sold through authorized distribution partners in more than 30 countries.

Product overview

Syntellix AG offers MAGNEZIX®, a biotransformable magnesium alloy platform technology that has revolutionized orthopedic and trauma implants. The core MAGNEZIX® material serves as the foundation for a comprehensive product portfolio including CS Screws (compression screws for fracture fixation), Pins (bone pins for small bone fragments), CBS Screws (cortical screws with safety drive), StarFuse® (specialized toe joint fusion implants), and IFSc (interference screws for ligament reconstruction). All products share the key property of being metallically stable like titanium but fully resorbed and transformed into natural bone tissue, eliminating the need for removal surgery.

Differentiator

Problem solved

Functional benefit

Brands

• MAGNEZIX®: World's first biotransformable metallic material for implants. CE-marked (Europe) and HSA-approved (Singapore) for medical applications. Used for bone fixation in orthopaedics, traumatology, and sports surgery. Properties include metallic stability similar to titanium, osteoconductivity, infection inhibition, and complete biotransformation into bone tissue.

Products and services

• MAGNEZIX® CS Screws (Compression Screws) Compression screws manufactured from the MAGNEZIX® biotransformable magnesium alloy, available in diameters 2.0mm, 2.7mm, 3.2mm, and CSc 4.8mm. The screws feature self-tapping tips to reduce operation time and a cannulated design (CS 2.7, CS 3.2, CSc 4.8) for minimally invasive insertion over a guide wire. Different thread pitches generate compressive forces for interfragmentary compression. Indicated for orthopedic bone fixation in hospitals and orthopedic practices.
• MAGNEZIX® Pins Bioabsorbable bone pins made from MAGNEZIX® magnesium alloy with mechanical stability up to 5 times higher than PLA/PGA polymer implants. Available in diameters 1.5mm, 2.0mm, 2.7mm, and 3.2mm. The flat head enables stable reduction, and symmetric collars compress free bone fragments during impaction. Designed for fracture fixation in trauma and sports surgery.
• MAGNEZIX® CBS Screws (Cortical Bone Screws) Cortical bone screws manufactured from MAGNEZIX® biotransformable magnesium alloy, available in diameters 2.0mm, 2.7mm, and 3.5mm in various lengths. Designed with stable repositioning and compression characteristics. Features a patented safety drive that deforms if torsional load is too high (continued insertion possible via hexagonal screwdriver), and a thread design optimized for strong cortical bone fixation.
• MAGNEZIX® StarFuse® Specialized intramedullary arthrodesis implants made from MAGNEZIX® biotransformable magnesium alloy for PIP joint fusion of lesser toes (hammer/claw toe correction). Features a patented wing design acting as a mechanical stop during insertion and following reduction, a star-shaped profile for rotational stability, and a conical design for press-fit anchoring. Available in 0° and 10° angulation options.
• MAGNEZIX® IFSc (Interference Screw) Bioabsorbable interference screws manufactured from MAGNEZIX® magnesium alloy for cruciate ligament reconstruction. Used to fix soft tissue or bone-tendon grafts in press-fit technique. Features a dense, porous magnesium-based oxide surface layer acting as a passivating protective layer. Available in 7mm, 8mm, and 9mm diameters.
• MAGNEZIX® Biotransformable Implant Material (Platform) The underlying proprietary magnesium alloy material that forms the technology platform for all Syntellix orthopedic and trauma implants. Provides metallic stability similar to titanium combined with elasticity close to natural bone; is osteoconductive, infection-inhibiting, and fully resorbed and transformed into endogenous bone tissue with no metal remaining. CE-marked in Europe and HSA-approved in Singapore for medical applications.

Quantifiable outcome

• Implants are transformed into bone tissue by the body - no metal remains
• +1 more outcomes

Segments4 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

One partnership is on record.

• Research Institutions NetworkcoreStrategic or Co-development PartnerSyntellix established an interdisciplinary network with outstanding scientists at different research locations. The company achieved its breakthrough after only five years of research, combining scientific expertise with entrepreneurial courage. Three well-known experts in medicine, materials science and management came together in 2008 to create the disruptive magnesium alloy innovation.

Scale indicators2 records

Recent moves7 records

Expansion highlights5 records

Broad incumbents

• Integra LifeSciences: US-listed specialty medtech with strong orthopedic extremity and neurosurgery franchises including bioresorbable and traditional fixation products. Comparable as a mid-sized platform that has historically in-licensed/integrated smaller innovation-driven implant companies.
• DePuy Synthes (Johnson & Johnson): J&J's orthopedic and trauma franchise, the dominant global supplier of screws, plates, and intramedullary nails. Sets the standard of care against which any new fixation material (including bioresorbable) must compete; also the most likely strategic partner for global rollout of magnesium technology.
• Stryker: Global orthopedic trauma and extremities incumbent with extensive screw and plate portfolio plus acquired Wright Medical extremities business. Comparable as the dominant channel through which bioabsorbable implant technology eventually reaches hospitals and as potential acquirer/licensor of magnesium IP.
• Arthrex: Privately held leader in sports medicine and orthopedics with deep roots in bioabsorbable interference screws, suture anchors, and toe fusion devices. Strong direct competitor in the IFSc and StarFuse® call points and a benchmark for surgeon-training-driven sales execution.
• Smith & Nephew: Global orthopedic and sports medicine major with screw, pin, and anchor product lines serving the same orthopedic/trauma/sports surgeon customer base. Broad incumbent whose sports medicine franchise competes head-to-head with MAGNEZIX® IFSc interference screws.

Direct peers

• Bioretec: Finnish orthopedics company commercializing bioresorbable PLA-based bone implants (screws, pins, anchors) for fracture fixation and sports injuries. Direct substitute to MAGNEZIX® but polymer-based rather than magnesium-based, serving the same orthopedic trauma and sports surgeons.
• Biotronik: German privately-held medical device company best known for bioresorbable magnesium-alloy stents (Magmaris, DREAMS). Closest technological analog: also uses magnesium-alloy platform for transient implants and is headquartered in the same country, competing for the same underlying materials science expertise.
• Acumed: US-based extremities and trauma fixation specialist with screw and plate products targeting hand, wrist, foot and ankle surgeons. Overlaps directly with Syntellix's orthopedic and trauma indications and represents a potential US commercialization/distribution partner.

Emerging players

• ConforMIS: US-listed patient-specific knee implant company whose value proposition (customized, bone-preserving implants) intersects Syntellix's patient-friendly, bone-bioresorbable positioning in orthopedics, though focused on joint reconstruction rather than trauma fixation.
• Inion Oy: Finnish developer of bioresorbable polymer (PLGA, PLA) implants for craniomaxillofacial, orthopedic, and sports surgery. Competes for the same 'second-surgery elimination' positioning with the same surgeons, but in polymer rather than magnesium chemistry.

Market position

Strengths5 records

Weaknesses6 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/c/syntellixde
• LinkedInlinkedin.com/company/syntellix-ag

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Syntellix