AMPS

What AMPS does

AMPS is a privately held software company founded in 1998 that develops quantitative ECG and Holter analysis tools primarily for pharmaceutical clinical trials and cardiac safety assessment. The company serves three primary customer segments: pharmaceutical sponsors (Pfizer, Roche, AstraZeneca, Johnson & Johnson, Sanofi-Aventis), contract research organizations (IQVIA, ERT), and ECG device manufacturers (Philips, GE Healthcare, Mortara Instrument), with secondary distribution to academic institutions and hospitals. AMPS is headquartered in New York with its core development center in Montichiari, Italy, operates as an LLC, and has 11-50 employees.

The company's product portfolio is organized into two main suites. The resting ECG suite includes CalECG (on-screen measurement application), TrialPerfect (21 CFR Part 11 compliant back-end database), ECGSolve (multi-format command-line processing tool), FAT-QT (fully automated Thorough-QT analysis), and several viewers (ViewECG, ViewECG Web, FDAEcg Suite). The continuous ECG recording (Holter) suite is anchored by CER-S, a six-module platform incorporating the proprietary ABILE beat detection/classification and BRAVO measuring algorithms, complemented by Antares, WinAtrec, and Heartscope. AMPS also licenses the PMB-AMPS Holter Database containing over 2,000 annotated continuous ECG recordings. The company defined key regulatory standards including the ISHNE Format (1998) and the aECG XML Format for FDA submissions (2003).

AMPS generates revenue through software licensing (subscription/recurring) of its ECG analysis tools, professional services for FDA submission and file format conversion (volume-based pricing from $1-$15 per ECG plus data management fees), database licensing, and occasional regulatory workshops. The go-to-market is sales-led, distributing directly to enterprise customers globally with no disclosed funding, parent company, or institutional investors. The company reinvests over 50% of annual revenues into R&D, has been recognized with the FDA Commissioner's Special Citation (2003) and the ACC Honorary Fellowship (2009), and operates a sub-brand (AMPSMedical) targeting the broader healthcare market.

Name

AMPS

Legal name

Amps LLC

Website

https://amps-llc.com

Company type

Private

Founded year

1998

Operating status

Operating

Headcount range

11–50 employees

Short description

AMPS develops specialized software tools for quantitative ECG and Holter analysis used in pharmaceutical clinical trials. The company serves global pharmaceutical companies, CROs, and medical device manufacturers with proprietary algorithms, FDA submission compliance, and continuous ECG recording platforms.

Ownership category

akta.pro rank

Product category

Clinical Trial ECG Software

NAICS

Software Publishers (5132)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Medical Laboratories (8071)

akta.pro primary industry

Electronic Data Capture (EDC) Platforms (HLACAOAA)

akta.pro secondary industries

Regulatory Submissions & Clinical Content Management (eCTD/Publishing) (HLACAOAN), Cardiac Monitoring (ECG/Holter/Event/Patch, Loop Recorders) (HLAHACAB), Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM)

Keywords

• ECG analysis software
• Holter monitoring tools
• Clinical trial cardiac safety
• FDA ECG submission
• Quantitative ECG analysis

Headquarters

HQ city

New York

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Software Licensing: Licensing of ECG analysis software tools including CalECG, FAT-QT, TrialPerfect, ECGSolve, CER-S, ViewECG, and ViewECG Web to pharmaceutical companies, CROs, and ECG core laboratories for use in clinical trials.
2. FDA Submission Services: Format verification and FDA ECG Warehouse submission services for aECG and continuous ECG recordings with tiered pricing based on volume.
3. File Format Conversion Services: Conversion of ECG files from various proprietary formats to FDA-compliant HL7 aECG XML and ISHNE formats, plus paper ECG digitization.
4. PMB-AMPS Holter Database: Licensing of annotated Holter recording database containing over 2000 annotated and anonymized continuous ECG recordings for algorithm testing and validation.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

AMPS develops quantitative ECG analysis software tools for pharmaceutical clinical trials, supporting both resting ECGs and continuous ECG (Holter) recordings. The company licenses proprietary software platforms (CalECG, TrialPerfect, FAT-QT, CER-S, ViewECG) and provides regulatory services for FDA ECG Warehouse submissions, HL7 aECG XML format conversion, and ECG file format interoperability to pharmaceutical companies, CROs, and medical device manufacturers.

Product overview

AMPS is a software company specializing in quantitative ECG analysis for the pharmaceutical and clinical research industries. The company operates a multi-product portfolio organized around two main product families: (1) Resting ECG software tools including CalECG (on-screen measurement application for pharmaceutical trials), TrialPerfect (back-end database system for clinical trials, 21 CFR Part 11 compliant), ECGSolve (command-line ECG processing tool), FAT-QT (fully automated waveform analysis and categorization), and multiple viewers (ViewECG, ViewECG Web based on HTML5/JavaScript, FDAEcg Suite, Viewer Light); and (2) Continuous ECG Recording (Holter) tools including CER-S (the primary platform with six modules: Continuous ECG Viewer, aECG Generator, Beat Detection/Classification using the ABILE algorithm, Arrhythmia Analysis, Beat Measures using the BRAVO algorithm, and Rhythm & Beat Editing), Antares (12-lead ECG snapshot extraction), WinAtrec (Holter analysis with RR bin approach), and Heartscope (spectral analysis). Supporting resources include the PMB-AMPS Holter Database (over 2000 annotated recordings). AMPS also offers services including paper ECG digitization, ECG file format conversion, HL7 format verification and FDA ECG Warehouse submission, and secondary analysis services. The company has defined key industry standards including the ISHNE Format (1998) and aECG XML Format for the FDA (2003), and has received the FDA Commissioner's Special Citation (2003) and Honorary Fellowship Award of the American College of Cardiology (2009). AMPS invests over 50% of annual revenues in R&D.

Differentiator

Problem solved

Functional benefit

Brands

• AMPSMedical: A dedicated website for medical/healthcare products and services developed by AMPS.

Products and services

• CalECG On-screen measurement application for ECG signals designed for pharmaceutical trials. Supports digital ECGs in multiple formats including the annotated ECG (aECG) HL7 XML standard format.
• ECGSolve Command-line application for processing digital resting ECGs, comprising modules for ECG format conversion, ECG image generator, PDF ECG report generator, and ECG annotator engine.
• FAT-QT Fully Automated Thorough-QT software combining CalECG and FDAEcg Suite for fully automated rule-based waveform analysis and categorization of 12-lead ECGs using quality metrics.
• FDAEcg Suite HL7 XML viewer that replaces and extends the previous XMLFDA Full Functional viewer, providing modules for analysis of 12-lead resting ECGs.
• TrialPerfect 21 CFR Part 11 compliant back-end database providing a professional, secure, client/server environment for storage, analysis, interpretation, validation, and review of ECG traces in clinical trials.
• ViewECG General-purpose MS Windows ECG trace viewer for viewing ECG waveforms.
• ViewECG Web Web-based JavaScript ECG trace viewer based on HTML5 standard, providing fully-customizable display of digital ECGs supporting 10s Rhythm strip and Representative Beats.
• Viewer Light HL7 XML viewer that replaces the previous XMLFDA Viewer Light, providing lightweight ECG viewing functionality.
• CER-S (Continuous ECG Recording Suite) Continuous ECG Recording Suite platform with six modules for managing continuous ECG recordings: Continuous ECG Viewer, aECG Generator (Pollux), ECG Beat Detection and Classification, Arrhythmia Analysis, Beat Measures, and Rhythm & Beat Editing.
• Antares Tool for extracting 12-lead ECG snapshots from raw data of commercial Holter systems.
• WinAtrec Advanced analysis system for Holter recordings incorporating the RR bin approach and time templates, originally designed by Philippe Coumel's group at Lariboisiere Hospital in Paris.
• Heartscope Software providing detailed spectral analysis of cardiovascular signals.
• PMB-AMPS Holter Database Annotated Holter recording database containing over 2000 annotated and anonymized continuous ECG recordings with documented episodes of atrial fibrillation, various arrhythmias, and normal recordings.
• Paper ECG to Digital Service Scan service converting paper ECG traces to digital FDA-compliant HL7 XML format files using patented ECGScan software.
• ECG File Format Conversion Service Service converting digital ECG traces of various formats (Mortara XML, GE MUSE XML, Philips XML, Schiller XML, AMPS binary ECG, ISHNE, SCP, MIT) into FDA-compliant HL7 XML format.
• CER File Format Conversion Service Service converting digital Continuous ECG recordings (Holters) of various formats (Mortara H-Scribe, H12+, MIT-WFDB, Getemed, ST XML, MyPatch, Borsam, VivaLnk, Cortrium C3) into FDA-compliant ISHNE format files.
• HL7 ECG Format Verification and FDA ECG Warehouse Submission Service Service verifying HL7 XML standard conformity for resting and continuous recordings and guaranteeing files will not be rejected by FDA ECG Warehouse at submission, with direct submission capability.
• Secondary Analysis Services External support services including ad hoc secondary analysis for clinical trials: Holter-bin analysis, repolarization morphology assessment, JTp/TpTe interval measurement, heart variability packages, arrhythmia detection, beat-to-beat analysis, and signal-averaged analyses.
• For the Medical World Services Products and services dedicated to the medical environment including Tele-Cardiology service and Stress Measurement service, available via the AMPSMedical website.

Quantifiable outcome

• Over 50% revenue reinvested in R&D annually for 17+ years
• +1 more outcomes

Named customers15 records

Segments5 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

AI capability5 records

Feature8 records

Partnerships

Three partnerships are on record, tiered core.

• Cardioline SpAcoreStrategic or Co-development Partner · 15 February 2021Partnership combining AMPS software analytics with Cardioline high-performance ECG devices to provide end-to-end solutions for the clinical trials market. Cardioline is entering the clinical trials market with security and workflow functionality in its device portfolio.
• Dr. Pierre Maison-BlanchecoreStrategic or Co-development Partner · 7 April 2016Joint project to launch the PMB-AMPS annotated Holter recording database containing over 2000 annotated and anonymized continuous ECG recordings. Dr. Maison-Blanche brings his expertise from Paris cardiology work with Professor Philippe Coumel.
• Mortara InstrumentcoreStrategic or Co-development Partner · 3 October 2013Co-organization of Regulatory Review of Continuous ECGs workshop for FDA ECG Warehouse compliance, bringing together sponsors, ECG core labs, and FDA officials to discuss continuous ECG data standards and submission requirements.

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Emerging players

• iRhythm Technologies: iRhythm's Zio patch and AI-driven ECG analysis platform represent an emerging, AI-first approach to cardiac monitoring. While primarily a clinical ambulatory monitoring play, it competes for the same cardiac analytics talent and FDA-aligned ECG data workflows that AMPS serves.

Broad incumbents

• Philips Healthcare: Philips offers enterprise ECG/Holter management, cardiac monitoring, and clinical-trial cardiac safety solutions including its BioTelemetry acquisition. It is both an AMPS customer (format compatibility) and a broad incumbent competitor in cardiac diagnostics.
• GE Healthcare (MUSE): GE Healthcare's MUSE ECG management system is widely deployed in hospitals and clinical research. AMPS supports GE MUSE XML format conversion, making GE both a partner in interoperability and a broad incumbent competitor for ECG analysis platforms.

Direct peers

• Schiller AG: Schiller manufactures clinical ECG and Holter devices whose formats AMPS supports (Schiller XML). Schiller competes in cardiac diagnostics hardware and software for both clinical and research use.
• Cardioline SpA: Cardioline is a European ECG device manufacturer that has an active 2021 partnership with AMPS to jointly serve the clinical trials market. The partnership combines Cardioline hardware with AMPS analytics, positioning them as collaborators with overlapping go-to-market.
• Spacelabs Healthcare: Spacelabs offers Holter monitoring, resting ECG analysis, and cardiology information systems used in clinical trials and hospitals. It competes with AMPS in cardiac monitoring and ECG analysis software for clinical research.
• Mortara Instrument (now Baxter / Hillrom): Mortara is a major Holter and resting ECG device manufacturer whose formats AMPS explicitly supports. Mortara co-organizes AMPS's regulatory workshops and is both a partner for AMPS in clinical trials and a competing ECG platform vendor.
• ERT (legacy): ERT was the dominant cardiac safety CRO for clinical trials and a major AMPS customer. Now part of Clario, it represents both a top account and a direct competitor in cardiac safety ECG services for pharma sponsors.
• Clario (formerly ERT + Bioclinica): Clario is the leading global cardiac safety services provider for clinical trials, formed from the merger of ERT and Bioclinica. It directly competes with AMPS in ECG core lab services and cardiac safety analytics, and was historically an AMPS customer/licensee.

Others

• Medidata (Dassault Systèmes): Medidata is a leading clinical-trial technology platform that competes for the same pharma sponsor IT budgets as AMPS. It does not directly offer AMPS's specialized ECG analytics but is part of the broader clinical-trial software ecosystem in which AMPS sells.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights3 records

Customer concentration

• LinkedInlinkedin.com/company/amps-llc-ecg

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about AMPS