What Permedica Orthopaedics does

Permedica S.p.A. is an Italian orthopedic implant manufacturer headquartered in Merate (Lecco), Italy, founded in 1985 and operating as a privately-held S.p.A. The company designs, develops, and manufactures joint replacement prostheses for hip, knee, shoulder, foot, and maxillofacial applications, with both anatomical and reverse configurations and both cementless press-fit and cemented fixation options. Its core product portfolio spans the PROMISE S and EXACTA femoral stems, the JUMP System dual mobility and ACORN TRASER acetabular reconstruction systems, the GKS Prime Flex family of total knee prostheses, and the Mirai shoulder system (anatomical and reverse). The differentiating layer is six proprietary in-house surface and materials technologies: TRASER (3D-printed trabecular titanium with 70% porosity), VITAL-B (TiNbN PVD ceramic coating for hypoallergenic articulating surfaces), VITAL-E/VITAL-XE (vitamin E-stabilized polyethylene), HaX-Pore (titanium plus hydroxyapatite plasma spray), MICROLOY (precision CNC mirror polishing reducing polyethylene wear by 48%), and SILVER-PORE (silver-ion antimicrobial surface). The company also offers digital surgery solutions including CUVIS patient-specific instruments, 3D MIRAI pre-operative planning, and ORTHALIGN/NAVISWISS navigation, plus the PURIST anterior-approach positioning system developed in partnership with IOT.

The company operates a direct-to-medical-professional go-to-market model, selling implants, surgical instruments, and instruments directly to hospitals and orthopedic surgeons through field sales, surgeon education programs (School of Joints, Academy Symposia, wetlabs, reference center visits), and a multilingual website infrastructure (Italian, English, French, German, Spanish) indicating international reach. Permedica runs the full manufacturing process in-house in Italy, including PVD coating, additive manufacturing, CNC finishing, and plasma spray coating. Revenue is generated through hardware sales of implants and instruments to healthcare institutions on quote-based procurement terms typical of the medical device sector. The company is founder-Marco Perego led, family-controlled with no disclosed external private equity, venture capital, or strategic acquirer ownership, and no public listing. Reported revenue is not publicly disclosed; the company employs 51-100 people.

Name

Permedica Orthopaedics

Legal name

Permedica S.p.A.

Website

https://permedica.it

Company type

Private

Founded year

1985

Operating status

Operating

Headcount range

51–100 employees

Short description

Permedica S.p.A. is an Italian orthopedic implant manufacturer, founded in 1985 and headquartered in Merate, producing hip, knee, shoulder, foot, and maxillofacial prostheses with proprietary surface technologies (TRASER, VITAL-B, HaX-Pore, MICROLOY, SILVER-PORE) sold directly to hospitals and orthopedic surgeons across European markets.

Ownership category

akta.pro rank

Product category

Orthopedic Implants

NAICS

Surgical Appliance and Supplies Manufacturing (339113), Surgical and Medical Instrument Manufacturing (339112)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Orthopedic Joint Reconstruction Implants (Hip/Knee/Shoulder/Elbow/Ankle) (HLAHAEAA)

akta.pro secondary industry

Hip & Knee Reconstruction (Arthroplasty) (HLAKALAH)

Keywords

• Orthopedic implant manufacturing
• Joint replacement prostheses
• Hip arthroplasty implants
• Knee arthroplasty implants
• Orthopedic surface technology

Headquarters

HQ city

Merate

HQ country

Italy

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Orthopedic Implant Sales: Permedica manufactures and sells orthopedic implants including hip prostheses (stems, cups, femoral heads), knee prostheses (femoral and tibial components), shoulder prostheses (anatomical and reverse), foot implants, maxillofacial implants, and custom-made solutions. The company operates in the medical devices sector with products distributed through direct engagement with medical professionals and hospitals.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels3 records

Core offering

Permedica designs, manufactures, and sells orthopedic joint replacement implants for hip, knee, shoulder, foot, and maxillofacial applications, along with the surgical instruments used to implant them. Its products are enhanced by a set of proprietary in-house surface and materials technologies (TRASER 3D-printed titanium, VITAL-B PVD coating, VITAL-E/VITAL-XE vitamin E polyethylene, HaX-Pore plasma spray coating, MICROLOY precision finishing, and SILVER-PORE antimicrobial surface), and are supported by digital pre-operative planning tools and surgeon education programs.

Product overview

Permedica S.p.A. is an Italian orthopaedic implant company offering a comprehensive portfolio of joint replacement solutions across hip, knee, and shoulder categories. The product portfolio centers on femoral stems (PROMISE S, EXACTA, EXACTA S), dual mobility systems (JUMP System, ACORN TRASER), total knee systems (GKS PRIME Flex family, GKS One Evo, GKS AMSMART, TRASER Cones), and shoulder prostheses (Mirai System Anatomical and Reverse). These implants are enhanced by proprietary surface technologies including TRASER (3D printed trabecular titanium), HaX-Pore (plasma-spray titanium/hydroxyapatite), VITAL-B (TiNbN ceramic coating), VITAL-E/VITAL-XE (vitamin E stabilized polyethylene), MICROLOY (precision surface finishing), and SILVER-PORE (silver ion antimicrobial surface). Digital surgery solutions include CUVIS surgical planning, 3D MIRAI planning & PSI, and ORTHALIGN navigation, complemented by the PURIST patient positioning system for anterior approach surgery.

Differentiator

Problem solved

Functional benefit

Brands

• TRASER: Trabecular Laser Melted Titanium - 3D additive manufacturing technology for porous structures enabling osseointegration
• VITAL-B
• VITAL-E & VITAL-XE
• HAX-PORE
• MICROLOY
• SILVER-PORE

Products and services

• PROMISE S Anatomically-shaped femoral stem for hip arthroplasty available in 7 anatomical sizes, designed for press-fit and cemented applications with bone-sparing geometry and femoral neck preservation.
• EXACTA S Shortened version of the EXACTA stem (30% shorter) for cementless press-fit and cemented hip arthroplasty, available in 12 sizes (standard and lateral) with double HaX-Pore coating for primary stability and osseointegration.
• JUMP System Dual mobility hip system including JUMP System TRASER (3D printed trabecular titanium), JUMP System CEMENTED, and JUMP System TRASER Acetabular Cage for acetabular reconstruction and dual mobility applications.
• ACORN TRASER Acetabular reconstruction system utilizing TRASER trabecular titanium technology for enhanced osseointegration.
• Universal cup removal system Surgical instrument for acetabular cup removal during revision hip surgeries.
• GKS PRIME Flex Complete knee prosthesis system with multiple configurations: GKS PRIME Flex Mobile (VITAL-B coated), GKS PRIME Flex PS Mobile, GKS PRIME Flex CR, GKS PRIME Flex TRASER, GKS PRIME Flex PS, GKS BUTTERFLY, GKS Prime Flex SMART REVISION, and GKS PRIME Flex RKT, covering various surgical approaches and patient needs.
• GKS One Evo Primary total knee replacement system designed for standard knee arthroplasty procedures.
• GKS AMSMART Knee prosthesis system component within the GKS product family.
• TRASER Cones Knee revision component utilizing TRASER trabecular titanium technology for enhanced fixation in revision procedures.
• Mirai System Shoulder prosthesis system available in Anatomical and Reverse configurations for total shoulder arthroplasty, including Mirai R Glenoideo Baseplate and Conical Humeral core components.
• CUVIS Surgical Planning Patient-specific instrument (PSI) system for pre-operative planning and surgical guidance based on 3D CT scan data, enabling precise bone cutting and implant positioning.
• 3D MIRAI Planning & PSI 3D pre-operative planning and patient-specific instruments using CT imaging for personalized joint replacement surgery.
• ORTHALIGN / NaviSwiss hip navigation Computer-assisted surgery navigation system for hip replacement procedures.
• PURIST System Patient positioning system developed in partnership with IOT for anterior approach hip surgery, designed to enhance surgeon efficiency and control during procedures.

Quantifiable outcome

• 48% reduction in polyethylene wear on knee femoral condyles with MICROLOY treatment compared to conventional finishing

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

One partnership is on record.

• IOTsupportingTechnology or IntegrationPartnership with IOT for the PURIST system - a patient positioning solution for anterior approach hip surgery. The PURIST is a next-generation positioning system designed to enhance surgeon efficiency and control during the procedure. It is easy to maneuver, user-friendly, and precise, offering clinical and operative advantages.

Recent moves6 records

Expansion highlights10 records

Broad incumbents

• Zimmer Biomet: One of the world's largest orthopedic implant manufacturers with a comprehensive hip, knee, and shoulder portfolio. Directly comparable as a broad incumbent competing in the same primary joint reconstruction segments as Permedica, though at vastly greater scale and brand recognition.
• Stryker Corporation: Global medical device leader with major orthopedic implants (hip, knee, shoulder) and the Mako robotic surgery platform. Competes with Permedica across primary and revision joint reconstruction and represents the scale ceiling for independent orthopedic players.
• Smith & Nephew: UK-based orthopedic implant manufacturer with established hip, knee, and shoulder reconstruction franchises plus the CORI robotic system. Directly comparable in product scope to Permedica, though serving a much larger global footprint.
• DePuy Synthes (Johnson & Johnson): J&J's orthopedic franchise covering hip, knee, shoulder, and trauma. Directly competes with Permedica in primary arthroplasty and benefits from deep hospital relationships and clinical evidence budgets that smaller players cannot match.
• B. Braun / Aesculap: German medical device group with an orthopedic implants division (Aesculap) covering hip and knee arthroplasty. Comparable as a broader European incumbent competing in the same primary joint reconstruction categories as Permedica.

Direct peers

• Exactech: US-based orthopedic implant company focused on hip, knee, and shoulder arthroplasty with surgeon-targeted education programs. Most closely comparable to Permedica as a focused joint reconstruction specialist with a similar scale and surgeon-relationship-driven business model.
• Medacta International: Swiss-family-owned orthopedic company specializing in hip, knee, and shoulder implants with strong European roots and growing global presence. Highly comparable to Permedica in profile: privately-held, European-anchored, focused on primary and revision joint reconstruction with proprietary technology platforms.
• Waldemar Link: German family-owned manufacturer of hip, knee, and revision orthopedic implants. Directly comparable as a similarly-sized European orthopedic specialist with a comparable product breadth and surgeon-direct sales model.
• Mathys European Orthopaedics: Swiss orthopedic implant manufacturer with hip, knee, and shoulder portfolios, owned by 41 Holding. Closely comparable in European specialty orthopedic niche, family/private ownership profile, and focus on primary and revision arthroplasty.
• Corin Group: UK-based orthopedic implant manufacturer focused on hip and knee replacement with emphasis on innovative bearing surfaces and patient-specific solutions. Directly comparable as a similarly-sized European-focused joint reconstruction specialist with proprietary technology differentiation.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xtiktok.com/@permedica
• Facebookfacebook.com/permedica
• LinkedInlinkedin.com/company/permedica-spa
• Instagramfacebook.com/permedica

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Permedica Orthopaedics