AlphaStem
Alpha-Stim is a privately held US medical device company that manufactures FDA-cleared Class II electrotherapy devices (Alpha-Stim AID and Alpha-Stim M) using patented Cranial Electrotherapy Stimulation and Microcurrent Electrical Therapy to treat anxiety, insomnia, depression, and pain without drugs, selling directly to consumers, veterans, first responders, and healthcare providers.
- Company typePrivate
- Founded1981
- HeadquartersAtlanta, United States
- Headcount11–50
- GTM typeB2C
- OfferingHardware or Manufacturing
What AlphaStem does
Alpha-Stim, legally Electromedical Products International, Inc., is a privately held US medical device company founded in 1981 and headquartered in Mineral Wells, Texas. The company designs, manufactures, and markets FDA 510(k)-cleared Class II electrotherapy devices for the drug-free treatment of anxiety, insomnia, depression (approved outside the US), and acute, chronic, and post-traumatic pain. Its core technology rests on two proprietary modalities: Cranial Electrotherapy Stimulation (CES), delivered via earclip electrodes to modulate brain network activity, and Microcurrent Electrical Therapy (MET), delivered via handheld Smart Probes or self-adhesive AS-Trodes for localized pain relief. The flagship Alpha-Stim M device uniquely combines both CES and MET in a single handheld unit; the Alpha-Stim AID provides CES-only functionality. Both are protected by three granted US patents (8,612,008; 8,457,765; 8,463,406), and the company's clinical evidence dossier exceeds 100 studies covering 8,800+ participants accumulated over 40+ years.
The company sells hardware directly to consumers through alpha-stim.com at $882 for the AID and $1,363 for the M, plus a full accessories line (electrode pads, lead wires, conducting solution, carry cases) priced $10.50-$42 that generates recurring revenue. In the US, a prescription is required and can be obtained either through a healthcare provider or via the company's telehealth referral program at $99 per appointment (available in most states except Rhode Island and Vermont); internationally, devices are available over-the-counter. Alpha-Stim also operates the Provider Plus Program, which offers volume discounts and clinical education to healthcare practitioners and clinics, and publishes practitioner-targeted webinars covering integrative, telehealth, addiction, and psychiatry applications. Customer segments span individual consumers, US veterans and active military, first responders (police, fire, EMS), healthcare providers, professional sports organizations, and a long-tail of celebrity and influencer users — supported by a multi-channel marketing strategy spanning the company website, social media (Facebook, YouTube, LinkedIn, Instagram), testimonial content, and clinical research publications. The company has no disclosed external VC/PE backing and has remained bootstrapped through its 40+ year operating history.
AlphaStem firmographics
Firmographics- Name
- AlphaStem
- Legal name
- Electromedical Products International, Inc.
- Website
- https://alpha-stim.com
- Company type
- Private
- Founded year
- 1981
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Alpha-Stim is a privately held US medical device company that manufactures FDA-cleared Class II electrotherapy devices (Alpha-Stim AID and Alpha-Stim M) using patented Cranial Electrotherapy Stimulation and Microcurrent Electrical Therapy to treat anxiety, insomnia, depression, and pain without drugs, selling directly to consumers, veterans, first responders, and healthcare providers.
- Ownership category
- akta.pro rank
AlphaStem industry classification
Industry- Product category
- Neuromodulation Medical Devices
- NAICS
- Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)
- SIC
- Electromedical & Electrotherapeutic Apparatus (3845)
- akta.pro primary industry
- Mental Wellness & Stress Management Devices (Biofeedback, Meditation/Neurostimulation Devices) (CRACAQAL)
Keywords
Where AlphaStem is headquartered
LocationHeadquarters
- HQ city
- Atlanta
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
AlphaStem business model
Business model- GTM type
- B2C
- Offering type
- Hardware or Manufacturing
- Cost components
- Operations, Personnel, Technology or R&D, Marketing or Sales, Supply Chain
Revenue model
- Medical Device Sales: One-time hardware sales of Alpha-Stim AID ($882) and Alpha-Stim M ($1,363) devices. Includes 30-day money-back guarantee and 5-year limited warranty. Payment options include HSA/FSA funds, credit/debit cards, PayPal, and monthly payment plans.
- Accessories and Consumables: Recurring sales of replacement accessories including earclip electrodes, probe electrode pads, AS-Trode self-adhesive electrode pads, conducting solution refills, carry cases, and lead wires. Prices range from $10.50 to $42.00 per item.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Pay-as-you-go | Alpha-Stim AID device for anxiety, insomnia, and depression |
| One time/ perpetual license | Pay-as-you-go | Alpha-Stim M device for pain, anxiety, insomnia, and depression |
| Unit Pricing | Pay-as-you-go | Accessories and replacement parts |
Go-to-market motion2 records
Distribution channels4 records
Marketing channels7 records
AlphaStem product offering
Product offeringCore offering
Alpha-Stim manufactures and sells FDA-cleared handheld electrotherapy medical devices that deliver patented Cranial Electrotherapy Stimulation (CES) and Microcurrent Electrical Therapy (MET) to treat anxiety, insomnia, depression (outside the US), and acute, chronic, and post-traumatic pain. Its two flagship products, the Alpha-Stim AID (CES-only, $882) and Alpha-Stim M (CES + MET, $1,363), are sold direct-to-consumer via the alpha-stim.com website and dispensed through licensed healthcare providers and a telehealth prescription network.
Product overview
Alpha-Stim is a neuromodulation medical device company offering two primary FDA-cleared electrotherapy products: Alpha-Stim AID and Alpha-Stim M. Alpha-Stim AID is a cranial electrotherapy stimulation (CES) device for treating anxiety, insomnia, and depression, priced at $882. Alpha-Stim M combines CES and microcurrent electrical therapy (MET) to treat acute, chronic, and post-traumatic pain as well as anxiety, insomnia, and depression, priced at $1,363. Both devices use patented low-amplitude waveforms delivered via earclip electrodes. Alpha-Stim M additionally includes handheld Smart Probes and AS-Trode self-adhesive electrodes for targeted pain treatment. The product portfolio is supported by a comprehensive range of accessories including carry cases, electrode pads, conducting solution, and replacement parts. The company also provides telehealth consultation services and a mobile application for device control.
Differentiator
Problem solved
Functional benefit
Brands
- Alpha-Stim AID: FDA-cleared cranial electrotherapy stimulation (CES) device for treating anxiety, insomnia, and depression.
- Alpha-Stim M
Products and services
- Alpha-Stim AID FDA-cleared Class II cranial electrotherapy stimulation (CES) device that uses earclip electrodes to deliver a patented low-amplitude waveform to the brain for sustainable, long-term relief from anxiety, insomnia, and depression. Intended for adult consumers with a prescription (US) or OTC purchase (international).
- Alpha-Stim M FDA-cleared Class II medical device combining cranial electrotherapy stimulation (CES) for anxiety, insomnia, and depression with microcurrent electrical therapy (MET) for acute, chronic, and post-traumatic pain. Includes earclip electrodes and handheld Smart Probes or self-adhesive AS-Trode electrodes for targeted pain treatment.
- Alpha-Stim Felt Earclip and Probe Electrode Pads, Lead Wires, AS-Trodes, Conducting Solution, and Carry Cases Recurring-use consumables and accessories for Alpha-Stim AID and Alpha-Stim M devices, including boxes of 256 felt earclip electrode pads ($21), boxes of 100 probe electrode pads ($21), Alpha-Stim AID and M earclip electrodes ($42 each), AS-Trode self-adhesive silver electrode pads ($25), replacement lead wires for Alpha-Stim M ($10.50), Alpha-Stim M Smart Probes ($15.75), conducting solution refills ($15.75), and carry cases for both AID and M ($20 each).
Quantifiable outcome
- 61% average decrease in anxiety immediately after CES treatment; 94% after 5 weeks
- +4 more outcomes
Companies that use AlphaStem
Customer profileNamed customers6 records
Segments4 records
Ideal customer profiles4 records
AlphaStem technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature3 records
AlphaStem partnerships and signals
Strategic signalScale indicators5 records
Recent moves6 records
Expansion highlights6 records
AlphaStem competitors and assessment
Company assessmentBroad incumbents
- Cala Health: Cala Health develops FDA-cleared wearable electrical stimulation devices (Cala Trio for essential tremor) and is expanding into broader neurology indications — comparable as a transcutaneous neurostim company navigating FDA clearance and provider channels.
- Soterix Medical: Soterix Medical develops clinical-grade transcranial direct current stimulation (tDCS) and other neurostimulation platforms used in research and clinical settings — comparable as a neuromodulation hardware company serving mental health and pain indications.
- Inspire Medical Systems: Inspire markets an FDA-approved implantable neurostimulation device for obstructive sleep apnea, demonstrating the broader neurostim category's commercial and regulatory economics relevant to Alpha-Stim's insomnia positioning.
- ElectroCore: ElectroCore commercializes non-invasive vagus nerve stimulation (nVNS) devices (gammaCore) for migraine, cluster headache, and other neurological indications — comparable as a non-implantable, FDA-cleared neurostim business targeting chronic conditions.
- NeuroPace: NeuroPace markets an FDA-approved responsive neurostimulation system (RNS) for refractory epilepsy — adjacent to Alpha-Stim as a commercial neuromodulation business operating in CNS indications under FDA regulation.
Emerging players
- Pulsetto: Pulsetto is an emerging consumer vagus-nerve stimulation device focused on stress, anxiety, and sleep — overlapping with Alpha-Stim's mental wellness use cases through a lower-friction consumer OTC channel.
Direct peers
- Fisher Wallace Laboratories: Fisher Wallace makes FDA-cleared cranial electrotherapy stimulation (CES) devices for anxiety, insomnia, and depression — directly competing with Alpha-Stim AID on the same CES modality, indications, and direct-to-consumer channel.
- Apollo Neuroscience: Apollo produces a consumer wearable that delivers low-amplitude stimulation to modulate the nervous system for stress, sleep, and focus — overlapping with Alpha-Stim's mental wellness/stress indications via a consumer-DTC motion.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat5 records
Key risks5 records
Key highlights6 records
Customer concentration
AlphaStem social profiles
Digital presenceAlphaStem compliance and trust
Trust signalCompliance1 record
AlphaStem financial estimates
Financial estimateRevenue estimate
Valuation estimate
AlphaStem leadership team
Management profileNumber of profiles
Profiles2 records
AlphaStem funding detail
Funding detailFunding overview
Funding rounds2 records
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
AlphaStem M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about AlphaStem
What does AlphaStem do?
Alpha-Stim manufactures and sells FDA-cleared handheld electrotherapy medical devices that deliver patented Cranial Electrotherapy Stimulation (CES) and Microcurrent Electrical Therapy (MET) to treat anxiety, insomnia, depression (outside the US), and acute, chronic, and post-traumatic pain. Its two flagship products, the Alpha-Stim AID (CES-only, $882) and Alpha-Stim M (CES + MET, $1,363), are sold direct-to-consumer via the alpha-stim.com website and dispensed through licensed healthcare providers and a telehealth prescription network.
Is AlphaStem a public or private company?
AlphaStem is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was AlphaStem founded?
AlphaStem was founded in 1981. It employs 11 to 50 people.
Where is AlphaStem based?
AlphaStem is headquartered in Atlanta, United States, in the North America region.
How does AlphaStem make money?
Two revenue lines are on record. Medical Device Sales are the primary driver. The others are accessories and Consumables.
Who are AlphaStem's main competitors?
Broad incumbents on record are Cala Health, Soterix Medical, Inspire Medical Systems, ElectroCore and NeuroPace. Pulsetto is listed as an emerging player. Direct peers are Fisher Wallace Laboratories and Apollo Neuroscience.
Does AlphaStem have an API?
No public API is recorded for AlphaStem.
What industry is AlphaStem in?
AlphaStem's product category is Neuromodulation Medical Devices. Its primary akta.pro industry code is CRACAQAL, Mental Wellness & Stress Management Devices (Biofeedback, Meditation/Neurostimulation Devices). Its NAICS code is 334510 and its SIC code is 3845.