CREmedical

What CREmedical does

CREmedical is a privately held medical device company headquartered in Kingston, Rhode Island, that develops electroencephalography (EEG) and neuromodulation hardware based on its proprietary Tripolar Concentric Ring Electrode (TCRE) platform. The TCRE is a three-element sensor (outer ring, middle ring, center disc) that performs Laplacian calculations and common-mode noise cancellation at the electrode level, enabling what the company describes as superior artifact rejection, signal-to-noise ratio, and spatial resolution compared with conventional disc electrodes used in standard EEG. The company's product portfolio spans sensing and stimulation: the tEEG line (t-Lead TCRE sensors paired with t-Interface 20-channel and 2-channel preamplifiers) produces simultaneous tripolar and emulated conventional EEG signals and is engineered for plug-compatibility with at least ten incumbent EEG amplifier brands; the TFS neuromodulation line pairs concentric ring stimulation electrodes with a constant-current Transcranial Focal Stimulator for noninvasive focal brain stimulation. Four US patents (US8352012B2, US8615283B2, US8626259B2, US9399133B2) cover the core electrode geometry and stimulation device.

The business model is hardware sales of research-use-only instruments and consumables, priced on a quote-only basis, targeting epilepsy research and clinical care, brain-computer interface (BCI) R&D, cognitive neuroscience, and neuromodulation researchers. Distribution combines direct sales from headquarters with regional distributors in China (Shenzhen Hanix United), Japan (Physio-Tech), and South Korea (BIOTECH); all other markets are served directly. The company maintains a research-driven go-to-market centered on peer-reviewed publications, technical demonstration videos, and exhibition at major venues including the American Epilepsy Society Annual Meeting, Society for Neuroscience, IEEE EMBC, and Japan Neuroscience Society, with the founder-CEO Dr. Walt Besio actively presenting. The firm has not disclosed revenue, has no known outside equity investors, and has limited disclosed funding to two National Science Foundation grants totaling approximately $1.4M (2012 and 2014). Headcount sits in the 1–10 range and the company operates as a founder-led spin-out leveraging Dr. Besio's academic position at the University of Rhode Island.

Name

CREmedical

Legal name

CREmedical

Website

https://cremedical.com

Company type

Private

Founded year

2011

Operating status

Operating

Headcount range

1–10 employees

Short description

CREmedical, a Kingston, Rhode Island-based private medical device company, develops Tripolar Concentric Ring Electrode (TCRE)-based EEG sensors, preamplifiers, and noninvasive transcranial focal electrical stimulators sold for research use to epilepsy, brain-computer interface, cognitive neuroscience, and neuromodulation research groups worldwide.

Ownership category

akta.pro rank

Product category

Neurotechnology EEG Equipment

NAICS

Electromedical and Electrotherapeutic Apparatus Manufacturing (334510), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (3345)

SIC

Electromedical & Electrotherapeutic Apparatus (3845)

akta.pro primary industry

Neurological Monitoring (EEG, Seizure/Sleep/Neuro Wearables) (HLAHACAE)

Keywords

• EEG electrode technology
• Brain sensing equipment
• Neuromodulation devices
• Concentric ring electrodes
• Transcranial electrical stimulation

Headquarters

HQ city

Kingston

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Personnel, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Hardware Sales - t-Leads (TCRE Sensors): Sale of t-Lead sensors (tripolar concentric ring electrodes) for EEG recording. Each sensor consists of gold-plated TCRE on FR-4 substrate with shielded cable. Sold as standalone products for research use.
2. Hardware Sales - t-Interface Pre-amplifiers: Sale of t-Interface 20-channel and t-Interface 2-channel pre-amplifiers that configure and amplify signals from t-Leads. These proprietary interfaces are required to operate the TCRE sensors with standard EEG amplifiers.
3. Hardware Sales - Concentric Ring Electrodes for Stimulation: Sale of Concentric Ring Electrodes (CRE) for transcranial focal stimulation. Includes CRE electrodes with outer ring diameters of 10mm or 6mm, and the Transcranial Focal Stimulator device that provides constant current stimulation with configurable parameters.
4. Transcranial Focal Stimulator: Constant current stimulator compatible with CRE electrodes. Provides up to 50 mA current, pulse durations 10-500 µs, frequencies 5-500 Hz, with built-in impedance checking. Four arbitrary waveforms available in addition to pulse trains.

Go-to-market motion3 records

Distribution channels4 records

Marketing channels5 records

Core offering

CREmedical designs, manufactures, and sells hardware for brain sensing and neuromodulation based on proprietary Tripolar Concentric Ring Electrode (TCRE) technology. Its product line includes t-Lead sensors and t-Interface pre-amplifiers that deliver tEEG (Tripolar EEG) recordings with superior artifact rejection and spatial resolution, plus concentric ring electrodes and a Transcranial Focal Stimulator (TFS) for noninvasive focal stimulation. Products are sold for research use to neuroscience and epilepsy researchers and clinicians globally, with distribution direct from the US and via regional partners in China, Japan, and South Korea.

Product overview

CREmedical offers an integrated platform of hardware and sensor technologies for brain sensing and neuromodulation. The core product line consists of TCRE (Tripolar Concentric Ring Electrode) sensors and two complementary systems: tEEG for brain signal acquisition and TFS for neuromodulation. The t-Lead is the TCRE-based sensor that works with t-Interface preamplifiers (available in 20-channel and 2-channel configurations) to deliver high-fidelity tEEG signals. The TFS system includes Concentric Ring Electrodes for stimulation paired with the Transcranial Focal Stimulator device. These products work together to provide researchers with superior EEG signal quality and focal electrical stimulation capabilities, with t-Interface supporting compatibility with major EEG amplifier brands including Brain Vision, Brain Products, g.tec, and others.

Differentiator

Problem solved

Functional benefit

Brands

• t-Lead: Tripolar Concentric Ring Electrode (TCRE)-based sensor for acquiring EEG signals
• t-Interface
• CRE (Concentric Ring Electrode)
• Transcranial Focal Stimulator
• tEEG
• TFS
• TCRE

Products and services

• t-Lead (TCRE Sensor)

Quantifiable outcome

• Signal-to-noise ratio improved by 375-420% compared to conventional EEG
• +8 more outcomes

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration10 records

Feature4 records

Partnerships

Three partnerships are on record, tiered regional coverage.

• Shenzhen Hanix United, Inc.regional coverageChannel Partner/ Reseller/ DistributorRegional distributor for China market. Handles sales, customer support, and service for CREmedical products in China. Located in Shenzhen with contact person Mr. Xu Feng.
• Physio-Tech Co. Ltd.regional coverageChannel Partner/ Reseller/ DistributorRegional distributor for Japan market. Provides sales and support services for CREmedical products in Japan. Located in Tokyo with contact person Mr. Shigenori Someya.
• BIOTECHregional coverageChannel Partner/ Reseller/ DistributorRegional distributor for South Korea market. Handles sales and customer support for CREmedical products in Korea. Located in Seoul with contact person Mr. T H Kim.

Scale indicators4 records

Recent moves5 records

Expansion highlights4 records

Direct peers

• Brain Products GmbH: Leading European manufacturer of EEG hardware and software for research and clinical use. Direct competitor to CREmedical in the research-grade EEG sensor and amplifier market, with overlapping customer base in academic neuroscience and clinical neurology.
• g.tec medical engineering: Austrian manufacturer of high-performance EEG, BCI, and brain-stimulation systems. Direct competitor in research-grade EEG acquisition and BCI hardware, with strong overlap in BCI and neuromodulation research customers.
• ANT Neuro: Dutch manufacturer of EEG, MEG, and TMS systems widely used in epilepsy monitoring and neuroscience research. Direct competitor in scalp-EEG hardware for clinical and research applications.
• Compumedics (Neuroscan): Australian-listed company (and its Neuroscan brand) producing EEG, PSG, and neurology diagnostic systems. Direct competitor in EEG hardware and clinical neurology applications including epilepsy monitoring.
• Wearable Sensing: US-based developer of dry-electrode EEG headsets and wearable EEG systems. Direct competitor in next-generation electrode technology targeting research, BCI, and applied neuroscience markets.

Broad incumbents

• Natus Medical (Natus Neuro): Large established neurology diagnostics company (Grass, Nicolet, XLTEK brands) selling clinical EEG, EMG, and ICU monitoring systems. Broad incumbent whose clinical-EEG and long-term epilepsy monitoring products compete in adjacent tiers of the same market.
• Philips (EGI / Electrical Geodesics): EGI (now part of Philips) makes high-density EEG systems for research and clinical use. Broad incumbent with deep clinical channels and large installed base, competing for the same research and clinical EEG budgets.

Emerging players

• OpenBCI: Open-source EEG and biosensing hardware company targeting BCI research, education, and hobbyist markets. Emerging player with partial overlap in low-cost research-grade EEG sensors and BCI applications.
• Emotiv: Consumer and research EEG headset maker (EPOC, Insight) with focus on BCI, neurofeedback, and applied research. Emerging player with overlapping BCI and neuroscience research use cases, though at lower signal-fidelity tier than CREmedical.

Others

• Blackrock Microsystems: Specialist in invasive neural recording and stimulation (NeuroPort, Utah Array) used in BCI and clinical research. Adjacent peer serving the same neuroscience and BCI research customers but with invasive rather than non-invasive electrodes.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds2 records

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about CREmedical